National Heart, Lung, and Blood Institute (NHLBI): all 1,143 studies

Page 1 of 12. Open to participants first (72), then studies with results posted, then the rest; newest registration first within each.

• Epcoritamab as Consolidative Therapy for Waldenstr(SqrRoot)(Delta)m Macroglobulinemia (WM) Treated With a Bruton Tyrosine Kinase Inhibitor (BTKi)Not yet recruitingNCT07882173Phase 2
• Metabolic Impact of VLCPUFA-Rich Fish Oil: A Clinical Study on Omega-3 Index Enhancement in Healthy IndividualsRecruitingNCT07882160Not applicable
• NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label DevicesNot yet recruitingNCT07806149Not applicable
• Nemtabrutinib for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Leukemia (SLL) Refractory to Covalent Bruton Tyrosine Kinase Inhibitor or Pirtobrutinib and Previously Treated With a BCL2 InhibitorNot yet recruitingNCT07796373Phase 2
• Immune Dysregulation During Sepsis: A Natural History CohortNot yet recruitingNCT07735741
• Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic HyperlipidemiaNot yet recruitingNCT07715890Not applicable
• Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT ImagingRecruitingNCT07613099Phase 3
• Partial Stem Cell Transplant for Sickle Cell Disease From Matched DonorsRecruitingNCT07599176Phase 1/2
• Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell DiseaseRecruitingNCT07566494Phase 1
• GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chronic Rejection in Lung TransplantationRecruitingNCT07516379
• Immune Profiling of CLL/SLL Treated With First-Line PirtobrutinibRecruitingNCT07428707Early Phase 1
• EDEN Intracardiac Electrogram Recording and Classifying SystemEnrolling by invitationNCT07137455Not applicable
• Platelet Volunteers, Longitudinal and Multi-omic StudyRecruitingNCT07137429
• Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research StudyEnrolling by invitationNCT07102849
• Healing Within: Mindfulness Smoking Cessation InterventionRecruitingNCT07013968Not applicable
• Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific AntibodiesRecruitingNCT06948097Phase 1
• VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) CathetersEnrolling by invitationNCT06940752Not applicable
• Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological InvolvementRecruitingNCT06923072Phase 2
• Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic ConditionsRecruitingNCT06676046
• OurSleepKit To Support CPAP AdherenceRecruitingNCT06621511Not applicable
• Thrombosis and Inflammation in Vessels Initiative (TIVI)RecruitingNCT06552767
• Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin LabelingRecruitingNCT06313398Early Phase 1
• Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)Enrolling by invitationNCT06280820
• Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell TransplantationRecruitingNCT06093867
• Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus ErythematosusRecruitingNCT06032923Phase 1/2
• Study of Intravenous ZMA001 in Healthy SubjectsRecruitingNCT05967299Phase 1
• Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell DiseaseRecruitingNCT05904093Phase 1
• Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or VenetoclaxRecruitingNCT05724121
• Controls and Healthy Vasculature InitiativeRecruitingNCT05403151
• NHLBI-Emory Advanced Cardiac CT ReconstructionNot yet recruitingNCT05372627
• Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative TherapiesRecruitingNCT05213572
• Vaccine Responses in Patients With B Cell MalignanciesRecruitingNCT05170399Phase 4
• Natural History Study of CADASILRecruitingNCT05072483
• Natural History of Acquired and Inherited Bone Marrow Failure SyndromesRecruitingNCT05012111
• Technical Development of Cardiovascular Magnetic Resonance ImagingRecruitingNCT04927429
• Data Collection of Standard Care and Evaluation of NHLBI Patients and DonorsEnrolling by invitationNCT04450927
• Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)RecruitingNCT04304820Phase 2Results posted
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy VolunteersRecruitingNCT04216342Phase 1
• CHIP/CCUS Natural History ProtocolRecruitingNCT04102423
• Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in WomenRecruitingNCT04014348
• Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism LevelsRecruitingNCT04008368Phase 1/2
• Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)RecruitingNCT03986034Phase 2
• Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell DiseaseRecruitingNCT03685721
• Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) ImagingRecruitingNCT03581318
• Vascular Disease Discovery ProtocolRecruitingNCT03538639
• Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD ProphylaxisRecruitingNCT03520647Phase 2
• Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner SystemRecruitingNCT03331380Not applicable
• Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood EnvironmentsRecruitingNCT03288207Not applicable
• Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant OutcomeRecruitingNCT03173937Phase 1/2
• Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)RecruitingNCT02543996
• Genome Transplant DynamicsRecruitingNCT02423070
• Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)RecruitingNCT02417714
• Heart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss InterventionRecruitingNCT01927783
• Nebulized or Inhaled Albuterol for LymphangioleiomyomatosisRecruitingNCT01799538Phase 1/2
• Evaluating New Radiation Techniques for Cardiovascular ImagingRecruitingNCT01621594Not applicable
• Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cellsRecruitingNCT01174108Phase 2
• Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular SystemRecruitingNCT01143454
• Natural History of BronchiectasisRecruitingNCT00943514
• Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)RecruitingNCT00923507
• Collection of Lung Fluid and Tissue Samples for ResearchRecruitingNCT00471250
• Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy VolunteersRecruitingNCT00442195
• Causes and Natural History of DyslipidemiasRecruitingNCT00353782
• Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell TransplantsRecruitingNCT00106925
• Natural History of Sickle Cell DiseaseRecruitingNCT00081523
• Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family MembersEnrolling by invitationNCT00071045
• Genetic Basis of ImmunodeficiencyRecruitingNCT00055172
• Blood Collection for Research Related to Certain Diseases Involving Blood VesselsEnrolling by invitationNCT00047996
• Study of Skin Tumors in Tuberous SclerosisRecruitingNCT00001975
• Screening for Hematology Branch ProtocolsEnrolling by invitationNCT00001620
• Role of Genetic Factors in the Development of Lung DiseaseRecruitingNCT00001532
• Improved Methods of Cell Selection for Bone Marrow Transplant AlternativesRecruitingNCT00001529
• Study of the Disease Process of LymphangioleiomyomatosisRecruitingNCT00001465
• NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility StudyTerminatedNCT06269640Not applicableResults posted
• Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ FunctionActive, not recruitingNCT06145282Phase 1/2Results posted
• JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow FailureActive, not recruitingNCT05998408Phase 1/2Results posted
• JAK/STAT Inhibition in CNS Kohlmeier-Degos DiseaseCompletedNCT05998395Phase 1/2Results posted
• Study of the Selective GlyT1 Inhibitor Bitopertin for Steroid-Refractory Diamond-Blackfan AnemiaCompletedNCT05828108Phase 1/2Results posted
• NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR TrialCompletedNCT05666713Not applicableResults posted
• Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated CytopeniasTerminatedNCT05502783Phase 2Results posted
• Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human LungCompletedNCT05027958Early Phase 1Results posted
• Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENE-FORECAST): Sodium Intervention Trial (SIT)CompletedNCT04717336Not applicableResults posted
• Fostamatinib for Hospitalized Adults With COVID-19CompletedNCT04579393Phase 2Results posted
• Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell DiseaseCompletedNCT04514510Phase 2Results posted
• Red Cell Half Life Determination in Patients With and Without Sickle Cell DiseaseCompletedNCT04476277Early Phase 1Results posted
• Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in PsoriasisCompletedNCT04271735Not applicableResults posted
• Treatment of Refractory Diamond-Blackfan Anemia With EltrombopagCompletedNCT04269889Phase 1/2Results posted
• Duvelisib for Ibrutinib-Resistant Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaTerminatedNCT04209621Phase 2Results posted
• NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility StudyCompletedNCT03929913Not applicableResults posted
• Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni SyndromeCompletedNCT03789175Phase 1/2Results posted
• Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's Tyrosine Kinase Inhibitor (BTK-I)CompletedNCT03702231Phase 2Results posted
• HEPLISAV-B Hepatitis B Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's-Tyrosine Kinase Inhibitor (BTK-I)CompletedNCT03685708Phase 2Results posted
• The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure SubjectsTerminatedNCT03565328Phase 2Results posted
• Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve ReplacementTerminatedNCT03432494Not applicableResults posted
• Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective InvestigationCompletedNCT03381989Not applicableResults posted
• HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell CarcinomaActive, not recruitingNCT03354390Phase 1Results posted
• Discovery of Sirolimus Sensitive Biomarkers in BloodCompletedNCT03304678Phase 2Results posted
• Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) PatientsCompletedNCT03226691Phase 1Results posted
• Eltrombopag for Fanconi AnemiaActive, not recruitingNCT03206086Phase 2Results posted
• Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaCompletedNCT03204188Phase 2Results posted
• Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive GuidewiresTerminatedNCT03152773Not applicableResults posted

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