Zotiraciclib clinical trials
Also written TG02.
Includes 3 studies of Zotiraciclib citrate.
How each study uses zotiraciclib is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
8 studies that test it; most in 2016 (2)
| Year | Studies |
|---|---|
| 2010 | 1 |
| 2012 | 1 |
| 2016 | 2 |
| 2018 | 2 |
| 2019 | 1 |
| 2023 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 5 · Other 3
Tragara Pharmaceuticals, Inc. (2) · National Cancer Institute (NCI) (2) · Lee's Pharmaceutical Limited (2) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Targovax ASA (1)
Related medicines
As reviewed, each with the page that says it.
- One of Protein Kinase Inhibitors source
Studies
Open first, then newest update. How each study uses zotiraciclib is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 8
- 000860: A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) MutationsRecruitingPhase 1/2National Cancer Institute (NCI)NCT05588141Written as Zotiraciclib
- Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and GlioblastomaTerminatedPhase 1/2National Cancer Institute (NCI)NCT02942264Written as Zotiraciclib (TG02)
- Multi-kinase Inhibitor TG02 (TG02) in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma.CompletedPhase 1European Organisation for Research and Treatment of Cancer - EORTCNCT03224104Written as TG02
- Exploratory Study of TG02-treatment as Monotherapy or in Combination With Pembrolizumab to Assess Safety and Immune Activation in Patients With Locally Advanced Primary and Recurrent Oncogenic RAS Exon 2 Mutant Colorectal CancerTerminatedPhase 1Targovax ASANCT02933944Written as TG02-treatment
- Phase I Clinical Study of Oral TG02 Capsule in the Treatment of Recurrent / Progressive High-grade Glioma PatientsStatus unknownPhase 1Lee's Pharmaceutical LimitedNCT03904628Written as TG02 capsules oral administration, BIW in every 28d
- Study of TG02 Citrate in Patients With Advanced Hepatocellular CarcinomaWithdrawnPhase 1Lee's Pharmaceutical LimitedNCT03738111Written as TG02 Citrate
- Phase 1 Study of TG02 Citrate in Patients With Chronic Lymphocytic Leukemia and Small Lymphocytic LymphomaCompletedPhase 1Tragara Pharmaceuticals, Inc.NCT01699152Written as TG02 citrate
- Phase 1 Study of TG02 Citrate in Patients With Advanced Hematological MalignanciesCompletedPhase 1Tragara Pharmaceuticals, Inc.NCT01204164Written as TG02 citrate
Codes
What other systems call zotiraciclib · ClinicalTrials.gg INT035069
- UNII (FDA) 40D08182TTZOTIRACICLIBConfirmed FDA, Wikidata
- Wikidata Q27088971zotiraciclibConfirmed FDA, Wikidata
- NCI Thesaurus C171725ZotiraciclibOne source FDA
- DrugBank DB16656One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | 40D08182TT | ZOTIRACICLIB | Confirmed FDA, Wikidata |
| Wikidata | Q27088971 | zotiraciclib | Confirmed FDA, Wikidata |
| NCI Thesaurus | C171725 | Zotiraciclib | One source FDA |
| DrugBank | DB16656 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.