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Blast Crisis clinical trials

The registry lists 361 studies for Blast Crisis across more than 10 countries. 16 are recruiting or about to start. 43 of them are mainly about Blast Crisis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Status

Completed
252
Terminated
61
Recruiting
14
Withdrawn
11
Status unknown
10
Active, not recruiting
8

Phase

Phase 2
163
Phase 1
149
Phase 3
26
Phase 4
3
Early Phase 1
1

Where

United States
319
Canada
21
Germany
13
Italy
13
France
13
United Kingdom
7

Who runs them

Fred Hutchinson Cancer Center (41) · National Cancer Institute (NCI) (40) · M.D. Anderson Cancer Center (30) · Memorial Sloan Kettering Cancer Center (18) · Case Comprehensive Cancer Center (14) · City of Hope Medical Center (12) · Roswell Park Cancer Institute (8) · Masonic Cancer Center, University of Minnesota (8)

What is being tested here

Drugs under test in Blast Crisis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Ponatinib206
Cytarabine1020
Imatinib1015
Methotrexate1011
Dasatinib1011
Nilotinib106
Venetoclax103
Blinatumomab102
Edetic Acid102
Dexrazoxane101

Drug classes tested here Tyrosine kinase inhibitors (TKIs) 3 open · Antimetabolites 1 open · Alkylating agents 56 · Calcineurin inhibitors 20 · HDAC inhibitors 11

Coming up

0phase 3 studies under way
7studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 7

Who these studies take

Of the 14 Blast Crisis studies recruiting now, 9 (64%) set no upper age limit and 2 (14%) stop at 75 or younger. 6 (43%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 14
AgeWomenMen
104 (29%)4 (29%)
1812 (86%)12 (86%)
3012 (86%)12 (86%)
4012 (86%)12 (86%)
5012 (86%)12 (86%)
6513 (93%)13 (93%)
7512 (86%)12 (86%)
8511 (79%)11 (79%)

Across all 361 studies, recruiting or not: 34% stop at 75 or younger and 27% at 65; 47% take children; 0% are for women only and <1% for men only; 1% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Blast Crisis studies take

Of 25 phase 2 interventional studies under Blast Crisis, half reached primary completion within 119 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 1/288 mo65–106 · 13 studies——
Phase 2119 mo64–165 · 25 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Stopped1

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 361. Browse all 361 → or search them.