Drug
Zileuton clinical trials
Also written Zyflo.
- studies test it
- 15
- open now
- 0
- in phase 3
- 1
- first study started
- 2001
How studies write it
Studies that test it under each name
Studies by the year they started
15 studies that test it; most in 2007 (3)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2003 | 2 |
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 1 |
| 2007 | 3 |
| 2010 | 2 |
| 2011 | 1 |
| 2013 | 1 |
| 2014 | 1 |
| 2016 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 5
- Phase 2
- 8
- Phase 3
- 1
- Phase 4
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 4 · Other 11
Critical Therapeutics (3) · University of Massachusetts, Worcester (2) · National Cancer Institute (NCI) (1) · Alliance for Clinical Trials in Oncology (1) · University of Michigan (1) · Cornerstone Therapeutics Inc. (1) · Children's Hospital Medical Center, Cincinnati (1) · Washington University School of Medicine (1)
Often tested with
Tested in the same studies.
Aspirin (1) · Celecoxib (1) · Pioglitazone (1) · Losartan (1) · Acetylcysteine (1) · Pravastatin (1) · Erythromycin (1)
Studies
Open first, then newest update. How each study uses zileuton is read from its arms, and is right about nine times in ten.
Testing it · 15
- Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current SmokersCompletedPhase 2National Cancer Institute (NCI)NCT02348203Written as Zileuton
- Zileuton to Treat Adults With Chronic Obstructive Pulmonary Disease (The LEUKO Study)TerminatedPhase 3University of MinnesotaNCT00493974Written as Zileuton
- Evaluating the Safety of Zileuton (Zyflo®) in Combination With Dasatinib (Sprycel®) in Chronic Myelogenous LeukemiaTerminatedPhase 1University of Massachusetts, WorcesterNCT02047149Written as Zileuton (Zyflo®) Dasatinib (Sprycel®)
- Carboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung CancerCompletedPhase 2Alliance for Clinical Trials in OncologyNCT00070486Written as zileuton
- Zileuton for the Treatment of Idiopathic Pulmonary FibrosisCompletedPhase 2University of MichiganNCT00262405Written as zileuton
- Safety of Zileuton (Zyflo) in Combination With Imatinib Mesylate (Gleevec) in CML.TerminatedPhase 1University of Massachusetts, WorcesterNCT01130688Written as Zileuton
- Single Dose Bronchodilatory Study in AsthmaCompletedPhase 4Cornerstone Therapeutics Inc.NCT01805687Written as Zileuton extended release
- Trial of Zileuton CR in Children and Adults With Sickle Cell DiseaseCompletedPhase 1Children's Hospital Medical Center, CincinnatiNCT01136941Written as Zileuton
- Evaluation of Rosiglitazone Anti-inflammatory Effect With FDG-PET ImagingCompletedEarly Phase 1Washington University School of MedicineNCT01174056Written as Zileuton
- Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak SyndromeTerminatedPhase 1/2National Human Genome Research Institute (NHGRI)NCT00467831Written as Zileuton
- Zileuton in Preventing Lung Cancer in Patients With Bronchial DysplasiaCompletedPhase 2Barbara Ann Karmanos Cancer InstituteNCT00056004Written as zileuton
- Assessment of PFT, Safety, and PK of Zileuton Injection in Asthma PatientsCompletedPhase 2Critical TherapeuticsNCT00534625Written as zileuton
- Zileuton and Exhaled Nitric Oxide in AsthmaticsCompletedPhase 4Gelb, Arthur F., M.D.NCT00575861Written as zileuton
- Safety Study of Zileuton Injection in Patients With AsthmaCompletedPhase 1/2Critical TherapeuticsNCT00299065Written as Zileuton injection
- Study of Oral Zileuton in the Treatment of Moderate to Severe Facial Acne VulgarisStatus unknownPhase 2Critical TherapeuticsNCT00098358Written as Zileuton
Given in every arm · 1 — zileuton is usual care beside what is tested
As the comparator · 1 — what is tested is compared with zileuton
Codes
What other systems call zileuton · ClinicalTrials.gg INT003500
- MeSH (NLM) C063449zileutonConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) V1L22WVE2SZILEUTONConfirmed FDA, NLM, Wikidata
- RxNorm 40575Confirmed FDA, Wikidata
- Wikidata Q202998zileutonConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C26667ZileutonOne source FDA
- DrugBank DB00744One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C063449 | zileuton | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | V1L22WVE2S | ZILEUTON | Confirmed FDA, NLM, Wikidata |
| RxNorm | 40575 | — | Confirmed FDA, Wikidata |
| Wikidata | Q202998 | zileuton | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C26667 | Zileuton | One source FDA |
| DrugBank | DB00744 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.