Breast Neoplasms, Male clinical trials
The registry lists 286 studies for Breast Neoplasms, Male across more than 10 countries. 5 are recruiting or about to start. 94 of them are mainly about Breast Neoplasms, Male (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Cancer Institute (NCI) (57) · Alliance for Clinical Trials in Oncology (17) · University of Washington (17) · Memorial Sloan Kettering Cancer Center (9) · Case Comprehensive Cancer Center (8) · H. Lee Moffitt Cancer Center and Research Institute (7) · City of Hope Medical Center (7) · SWOG Cancer Research Network (6)
What is being tested here
Drugs under test in Breast Neoplasms, Male studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Anastrozole | 1 | 0 | 3 |
| Tamoxifen | 1 | 1 | 2 |
| Degarelix | 1 | 0 | 1 |
| Abemaciclib | 1 | 0 | 1 |
| Paclitaxel | 0 | 1 | 20 |
| Cyclophosphamide | 0 | 2 | 19 |
| Docetaxel | 0 | 0 | 15 |
| Trastuzumab | 0 | 1 | 14 |
| Doxorubicin | 0 | 2 | 14 |
| Bevacizumab | 0 | 2 | 12 |
Drug classes tested here Aromatase inhibitors 1 open · Antimitotic agents 47 · Tyrosine kinase inhibitors (TKIs) 34 · Antimetabolites 23 · Alkylating agents 22
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Apr 2027ETHAN - ET for Male BC · Jose Pablo Leone
- Apr 2027MALE Mamm Organoids · Regina Elena Cancer Institute
- Oct 2027Male breAsT cAncer preDisposition Factor: Creation of a Control Cohort 2 · Institut Claudius Regaud
- Oct 2027Access to Genetic Testing in Underserved Patients With Cancer · University of Southern California
Who these studies take
Of the 5 Breast Neoplasms, Male studies recruiting now, 5 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 3 (60%) for men only; 1 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 2 (40%) | 4 (80%) |
| 30 | 2 (40%) | 4 (80%) |
| 40 | 2 (40%) | 4 (80%) |
| 50 | 2 (40%) | 4 (80%) |
| 65 | 2 (40%) | 4 (80%) |
| 75 | 2 (40%) | 5 (100%) |
| 85 | 2 (40%) | 5 (100%) |
Across all 286 studies, recruiting or not: 3% stop at 75 or younger and 2% at 65; 7% take children; 2% are for women only and 5% for men only; 1% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Breast Neoplasms, Male studies take
Of 20 phase 2 interventional studies under Breast Neoplasms, Male, half reached primary completion within 49 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 44 mo20–54 · 15 studies | — | — |
| Phase 2 | 49 mo25–75 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting1
- Male breAsT cAncer preDisposition Factor: Creation of a Control Cohort 2Oct 29, 2026NCT07558343
Studies
Recruiting first, then most recently updated. Showing 50 of 286. Browse all 286 → or search them.
- Male breAsT cAncer preDisposition Factor: Creation of a Control Cohort 2RecruitingNCT07558343Not applicable1 country
- ETHAN - ET for Male BCRecruitingNCT05501704Phase 21 country
- Access to Genetic Testing in Underserved Patients With CancerRecruitingNCT06422455Not applicable1 country
- Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 StudyRecruitingNCT068058121 country
- MALE Mamm OrganoidsRecruitingNCT067866631 country
- Phase IIIb Study of Ribociclib + ET in Early Breast CancerActive, not recruitingNCT05827081Phase 316 countries
- A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of RecurrenceActive, not recruitingNCT06492616Phase 328 countries
- Ixabepilone and Vorinostat in Treating Patients With Metastatic Breast CancerCompletedNCT01084057Phase 11 country
- S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast CancerActive, not recruitingNCT01674140Phase 32 countries
- Divergent Long-Term Clinical Courses in Two Men With Breast CancerCompletedNCT078655071 country
- Combination Chemotherapy With or Without Trastuzumab in Treating Patients With Stage II or Stage III Breast CancerActive, not recruitingNCT00295893Phase 21 country
- HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast CancerCompletedNCT03387553Early Phase 11 country
- S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast CancerActive, not recruitingNCT00070564Phase 33 countries
- Paclitaxel and Trastuzumab With or Without Lapatinib in Treating Patients With Stage II or Stage III Breast Cancer That Can Be Removed by SurgeryCompletedNCT00770809Phase 32 countries
- Paclitaxel With or Without Carboplatin and/or Bevacizumab Followed by Doxorubicin and Cyclophosphamide in Treating Patients With Breast Cancer That Can Be Removed by SurgeryCompletedNCT00861705Phase 21 country
- Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Breast Cancer, Non-small Cell Lung Cancer, or Prostate CancerCompletedNCT02206334Phase 13 countries
- Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients of Different Ages With Metastatic Breast CancerActive, not recruitingNCT00609791Phase 21 country
- EORTC Quality of Life Measurement in Males With Breast CancerCompletedNCT074551101 country
- Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast CancerActive, not recruitingNCT03384914Phase 21 country
- Molecular Mechanisms of Clinical Resistance to Targeted Therapy Among Patients With Breast CancerCompletedNCT008977021 country
- Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)CompletedNCT02950259Phase 11 country
- A Study of PF-06873600 in People With CancerTerminatedNCT03519178Phase 1/26 countries
- Romidepsin and Abraxane in Treating Patients With Metastatic Inflammatory Breast CancerTerminatedNCT01938833Phase 1/21 country
- Azacitidine and Entinostat in Treating Patients With Advanced Breast CancerCompletedNCT01349959Phase 21 country
- Study on the Progress of Breast Cancer Cases in Males and the Assessment of Relapse RiskCompletedNCT038003551 country
- QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast CancerTerminatedNCT02751528Phase 11 country
- RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast CancerTerminatedNCT01217411Phase 1/21 country
- Testosterone & Tamoxifen TrialTerminatedNCT05156606Not applicable1 country
- Hypofractionated Image Guided Radiation Therapy in Treating Patients With Stage IV Breast CancerCompletedNCT017064321 country
- Finasteride (MK-0906) and Male Breast Cancer - A Register-Based Nested Case-Control Study (MK-0906-162/2003.021).CompletedNCT01703520
- Lapatinib and Tamoxifen in Treating Patients With Advanced or Metastatic Breast CancerCompletedNCT00424164Phase 11 country
- Sorafenib in Treating Patients With Metastatic Breast CancerCompletedNCT00096434Phase 21 country
- Vaccine Therapy in Treating Patients With Metastatic CancerCompletedNCT00020267Phase 11 country
- Sunitinib in Treating Patients With Newly Diagnosed Stage II or Stage III Breast Cancer That Can Be Removed by SurgeryCompletedNCT00482755Phase 21 country
- FDG PET and DCE-MRI in Predicting Response to Treatment in Patients With Breast CancerTerminatedNCT01931709Not applicable1 country
- Breast Cancer Registry for Participants With Breast Cancer or Characteristics of Hereditary Breast CancerCompletedNCT006667311 country
- A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast CancerCompletedNCT01101438Phase 34 countries
- The Genetic Education for Men Trial: Web-Based Education vs. Standard CareCompletedNCT02957981Not applicable1 country
- Ixabepilone and Hydroxychloroquine in Treating Patients With Metastatic Breast CancerTerminatedNCT00765765Phase 1/21 country
- Everolimus in Treating Patients WIth Recurrent or Metastatic Breast CancerCompletedNCT00255788Phase 21 country
- OGX-011 and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Solid TumorsCompletedNCT00471432Phase 1
- Pilot Study of Paclitaxel Plus Pembrolizumab in Metastatic HER2-Negative Breast CancerCompletedNCT03018080Phase 21 country
- Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal CancerCompletedNCT003039141 country
- Paclitaxel With or Without Bevacizumab in Treating Patients With Locally Recurrent or Metastatic Breast CancerCompletedNCT00028990Phase 32 countries
- Targeted T Cells After Neoadjuvant Chemotherapy in Treating Women With Stage II or III Breast Cancer Undergoing SurgeryTerminatedNCT01147016Phase 21 country
- Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast CancerCompletedNCT03112590Phase 1/21 country
- Optical Spectroscopy in Evaluating Tumor Margins in Patients Who Have Undergone Surgery for Breast TumorsCompletedNCT00625417Not applicable1 country
- Gemcitabine +/- Imatinib Mesylate, Patients w/Previously Treated Metastatic Breast CancerTerminatedNCT00323063Phase 21 country
- Propranolol Hydrochloride in Treating Patients With Locally Recurrent or Metastatic Solid Tumors That Cannot Be Removed By SurgeryCompletedNCT02013492Early Phase 11 country
- Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain MetastasesCompletedNCT00377156Phase 32 countries