Drug
Voclosporin clinical trials
Also written ISA247, LX211 and LUPKYNIS.
- studies test it
- 26
- open now
- 3
- in phase 3
- 13
- first study started
- 2004
Keep track of what changes. Save the voclosporin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
26 studies that test it; most in 2007 (3)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 2 |
| 2007 | 3 |
| 2009 | 1 |
| 2011 | 1 |
| 2013 | 1 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 2 |
| 2019 | 2 |
| 2020 | 1 |
| 2022 | 2 |
| 2023 | 1 |
| 2024 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 8
- Phase 3
- 13
- Phase 4
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 22 · Other 4
Aurinia Pharmaceuticals Inc. (17) · Lux Biosciences, Inc. (5) · Leiden University Medical Center (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · NephroNet, Inc. (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
Often tested with
Tested in the same studies.
Simvastatin (1) · Tacrolimus (1) · Cyclosporine (1) · Prednisolone (1) · Mycophenolic Acid (1)
Studies
Open first, then newest update. How each study uses voclosporin is read from its arms, and is right about nine times in ten.
Testing it · 26
- Assessing Residual Inflammation and Macrophage Presence in Lupus Nephritis After 3 Months of Intensified Treatment With Prednisolone, Mycofenolate Mofetil and Voclosporin as Compared to Mycofenolate Mofetil and PrednisoloneRecruitingPhase 4Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT07760480Written as Voclosporin (LUPKYNIS)
- PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus NephritisRecruitingPhase 4Aurinia Pharmaceuticals Inc.NCT07611214Written as LUPKYNIS
- Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy TrialRecruitingPhase 4NephroNet, Inc.NCT07225387Written as Voclosporin
- Voclosporin in Adolescent and Pediatric Subjects With Lupus NephritisTerminatedPhase 3Aurinia Pharmaceuticals Inc.NCT05288855Written as Voclosporin
- Long-Term Voclosporin Treatment in Adolescent and Pediatric Subjects With Lupus NephritisTerminatedPhase 3Aurinia Pharmaceuticals Inc.NCT05962788Written as voclosporin
- Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic LupusTerminatedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT05306873Written as Voclosporin
- Anti-Viral Effects of Voclosporin in COVID-19 Positive Kidney Transplant RecipientsCompletedPhase 2Leiden University Medical CenterNCT04701528Written as Voclosporin
- Aurinia Renal Response in Active Lupus With VoclosporinCompletedPhase 3Aurinia Pharmaceuticals Inc.NCT03021499Written as Voclosporin
- Randomized Placebo-controlled Study of ISA247 in Plaque PsoriasisCompletedPhase 3Aurinia Pharmaceuticals Inc.NCT00244842Written as voclosporin
- Aurinia Renal Assessments 2: Aurinia Renal Response in Lupus With VoclosporinCompletedPhase 3Aurinia Pharmaceuticals Inc.NCT03597464Written as Voclosporin
- Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of SimvastatinCompletedPhase 1Aurinia Pharmaceuticals Inc.NCT05306379Written as Voclosporin
- Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye SyndromeCompletedPhase 2/3Aurinia Pharmaceuticals Inc.NCT04147650Written as 0.05% Voclosporin Ophthalmic Solution (VOS)
- Dose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental GlomerulosclerosisTerminatedPhase 2Aurinia Pharmaceuticals Inc.NCT03598036Written as Voclosporin
- Ocular Tolerability of Voclosporin Ophthalmic Solution Versus Restasis® in Subjects With Dry Eye DiseaseCompletedPhase 2Aurinia Pharmaceuticals Inc.NCT03597139Written as Voclosporin Ophthalmic Solution
- AURA-LV: Aurinia Urinary Protein Reduction Active - Lupus With Voclosporin (AURA-LV)CompletedPhase 2Aurinia Pharmaceuticals Inc.NCT02141672Written as Voclosporin High Dose
- Aurinia Early Urinary Protein Reduction Predicts ResponseCompletedPhase 2Aurinia Pharmaceuticals Inc.NCT02949973Written as voclosporin
- Voclosporin in Healthy Japanese VolunteersCompletedPhase 1Aurinia Pharmaceuticals Inc.NCT02949999Written as Voclosporin
- Safety and Efficacy Study of Voclosporin and Tacrolimus in TransplantationWithdrawnPhase 3Aurinia Pharmaceuticals Inc.NCT01586845Written as voclosporin
- Study of ISA247 (Voclosporin) in De Novo Renal TransplantationCompletedPhase 2Aurinia Pharmaceuticals Inc.NCT00270634Written as Voclosporin
- Efficacy and Safety of Voclosporin to Treat Active Noninfectious UveitisCompletedPhase 3Lux Biosciences, Inc.NCT01243983Written as LX211
Codes
What other systems call voclosporin · ClinicalTrials.gg INT004628
- MeSH (NLM) C484071voclosporinConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 2PN063X6B1VOCLOSPORINConfirmed FDA, NLM, Wikidata
- RxNorm 2475166One source FDA
- Wikidata Q7939256voclosporinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C152902VoclosporinOne source FDA
- DrugBank DB11693One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C484071 | voclosporin | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 2PN063X6B1 | VOCLOSPORIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2475166 | — | One source FDA |
| Wikidata | Q7939256 | voclosporin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C152902 | Voclosporin | One source FDA |
| DrugBank | DB11693 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.