Drug
Thioguanine clinical trials
Also written Tabloid, Lanvis, WR-1141 and Tioguanine.
- studies test it
- 38
- open now
- 3
- in phase 3
- 20
- first study started
- 1994
Keep track of what changes. Save the Thioguanine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Combined with it in one product
Studies by the year they started
38 studies that test it; most in 2000 (3)
| Year | Studies |
|---|---|
| 1994 | 2 |
| 1995 | 1 |
| 1996 | 2 |
| 1997 | 1 |
| 1998 | 1 |
| 1999 | 1 |
| 2000 | 3 |
| 2001 | 1 |
| 2002 | 2 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 1 |
| 2007 | 2 |
| 2008 | 1 |
| 2010 | 2 |
| 2012 | 2 |
| 2014 | 2 |
| 2015 | 1 |
| 2016 | 2 |
| 2017 | 1 |
| 2019 | 3 |
| 2022 | 1 |
| 2024 | 1 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 19
- Phase 3
- 20
- Phase 4
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 38
Children's Oncology Group (14) · St. Jude Children's Research Hospital (4) · National Cancer Institute (NCI) (3) · Kjeld Schmiegelow (2) · Memorial Sloan Kettering Cancer Center (2) · Alliance for Clinical Trials in Oncology (1) · Kristoffer Rohrberg (1) · Universitätsklinikum Hamburg-Eppendorf (1)
Often tested with
Tested in the same studies.
Cyclophosphamide (23) · Cytarabine (23) · Daunorubicin (23) · Mercaptopurine (19) · Methotrexate (19) · Doxorubicin (16) · Vincristine (15) · Pegaspargase (14)
Studies
Open first, then newest update. How each study uses Thioguanine is read from its arms, and is right about nine times in ten.
Testing it · 38
- Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLyRecruitingPhase 3Children's Oncology GroupNCT03959085Written as Thioguanine
- Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and LymphomaRecruitingPhase 2St. Jude Children's Research HospitalNCT06533748Written as Thioguanine
- International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic LymphomaRecruitingPhase 3University Hospital MuensterNCT04043494Written as Thioguanine
- Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic LeukemiaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT02101853Written as Thioguanine
- A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic LeukemiaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT03914625Written as Thioguanine
- Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down SyndromeActive, not recruitingPhase 3Children's Oncology GroupNCT02521493Written as Thioguanine
- Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaActive, not recruitingPhase 2/3St. Jude Children's Research HospitalNCT03117751Written as Thioguanine
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive MutationsCompletedPhase 3National Cancer Institute (NCI)NCT02883049Written as Thioguanine
- Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic LymphomaCompletedPhase 3Children's Oncology GroupNCT01190930Written as Thioguanine
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedPhase 2Alliance for Clinical Trials in OncologyNCT00558519Written as thioguanine
- Thiopurine Enhanced Mutations for PD-1/Ligand-1 EfficacyCompletedPhase 1/2Kristoffer RohrbergNCT05276284Written as Atezolizumab, 6-mercaptopurine, 6-thioguanine
- DEC-C and Thioguanine for R/R AMLWithdrawnPhase 2Columbia UniversityNCT06351306Written as Thioguanine (Tabloid ®)
- Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALLCompletedPhase 2/3Universitätsklinikum Hamburg-EppendorfNCT01228331Written as Thioguanine
- Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedPhase 3Children's Oncology GroupNCT00005596Written as thioguanine
- Combination Chemotherapy in Treating Children With Acute Lymphoblastic LeukemiaCompletedPhase 3Children's Oncology GroupNCT00005585Written as thioguanine
- Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic LeukemiaCompletedPhase 3St. Jude Children's Research HospitalNCT00549848Written as Prednisone, Vincristine, Daunorubicin, PEG-L-asparaginase, Erwinia L-asparaginase, Doxorubicin, Cyclophosphamide, Cytarabine, Thioguanine
- German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)CompletedPhase 4Goethe UniversityNCT00198991Written as Thioguanine
- NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic LymphomaCompletedPhase 2St. Jude Children's Research HospitalNCT01451515Written as Thioguanine
- Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic SyndromesCompletedPhase 3Children's Oncology GroupNCT00369317Written as thioguanine
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedPhase 3Children's Oncology GroupNCT00103285Written as Thioguanine
See all 38 studies that test Thioguanine →
Given in every arm · 30 — Thioguanine is usual care beside what is tested
- A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)RecruitingPhase 2National Cancer Institute (NCI)NCT06124157Written as Thioguanine
- Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged LeukemiaRecruitingPhase 2National Cancer Institute (NCI)NCT06317662Written as Thioguanine
- Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic LeukemiaRecruitingPhase 3Alliance for Clinical Trials in OncologyNCT03150693Written as Thioguanine
- Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More TreatmentNot yet recruitingPhase 2SWOG Cancer Research NetworkNCT07636564Written as Thioguanine
- Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)RecruitingPhase 2St. Jude Children's Research HospitalNCT06390319Written as Thioguanine
- Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)Not yet recruitingPhase 2/3Children's Oncology GroupNCT07072585Written as Thioguanine
- Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic LeukemiaRecruitingPhase 1University of ChicagoNCT03571321Written as Thioguanine
- Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017RecruitingPhase 3Martin SchrappeNCT03643276Written as Tioguanin
- Ma-Spore ALL 2020 StudyRecruitingPhase 2National University Hospital, SingaporeNCT06336395Written as Thioguanine
- Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic LymphomaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT02112916Written as Thioguanine
- Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaActive, not recruitingPhase 3Children's Oncology GroupNCT03007147Written as Thioguanine
- A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic LeukemiaCompletedPhase 2Incyte CorporationNCT02723994Written as Thioguanine
- Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene RearrangementCompletedPhase 2National Cancer Institute (NCI)NCT02828358Written as Thioguanine
- Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)WithdrawnPhase 2National Cancer Institute (NCI)NCT06210750Written as Thioguanine
- International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic LeukemiaCompletedPhase 3University Hospital Schleswig-HolsteinNCT01117441Written as thioguanine
- Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic LeukemiaCompletedPhase 3Children's Oncology GroupNCT00075725Written as Thioguanine
- Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic LeukemiaCompletedPhase 3Children's Oncology GroupNCT00671034Written as Thioguanine
- Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia (Closed to Accrual 4-22-2011)CompletedPhase 1Children's Oncology GroupNCT00866307Written as Thioguanine
- ABT-751 With Chemotherapy for Relapsed Pediatric ALLTerminatedPhase 1/2Therapeutic Advances in Childhood Leukemia ConsortiumNCT00439296Written as 6-thioguanine
- Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic LymphomaCompletedPhase 3Children's Oncology GroupNCT00004228Written as thioguanine
Showing 20 of 30.
As the comparator · 2 — what is tested is compared with Thioguanine
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic LymphomaCompletedPhase 3National Cancer Institute (NCI)NCT00408005Written as Thioguanine
- Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First RemissionCompletedPhase 3Eastern Cooperative Oncology GroupNCT00002514Written as thioguanine
Codes
What other systems call Thioguanine · ClinicalTrials.gg INT008308
- MeSH (NLM) D013866ThioguanineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) FTK8U1GZNXTHIOGUANINEConfirmed FDA, NLM, Wikidata
- RxNorm 10485Confirmed FDA, Wikidata
- Wikidata Q27895847thioguanine hydrateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C876ThioguanineOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D013866 | Thioguanine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | FTK8U1GZNX | THIOGUANINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 10485 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27895847 | thioguanine hydrate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C876 | Thioguanine | One source FDA |
Also registered as thioguanine anhydrous (UNII WIX31ZPX66 · RxNorm 1546005).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.