Drug
Artemether clinical trials
- studies test it
- 17
- open now
- 1
- in phase 3
- 2
- first study started
- 2004
Keep track of what changes. Save the Artemether studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
16 studies that test it; most in 2012 (3)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 1 |
| 2008 | 1 |
| 2009 | 2 |
| 2011 | 1 |
| 2012 | 3 |
| 2014 | 2 |
| 2016 | 1 |
| 2022 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 2
- Phase 3
- 2
- Phase 4
- 9
What it is tested for
Each study’s main condition, where its own words name it.
- Malaria
- 10
Who runs them
Industry 4 · Other 13
University of California, San Francisco (2) · University of Cape Town (2) · Centers for Disease Control and Prevention (1) · Epicentre (1) · Thierry Buclin (1) · GlaxoSmithKline (1) · Universiteit Antwerpen (1) · Muhimbili University of Health and Allied Sciences (1)
Often tested with
Tested in the same studies.
Lumefantrine (14) · Artesunate (3) · Amodiaquine (3) · Tafenoquine (2) · Efavirenz (2) · Quinine (1) · Sulfadoxine (1) · Pyrimethamine (1)
Studies
Open first, then newest update. How each study uses Artemether is read from its arms, and is right about nine times in ten.
Testing it · 17
- Southeast Asia Dose Optimization of TafenoquineRecruitingPhase 4University of OxfordNCT04704999Written as Artemether 20 mg-Lumefantrine 120 mg
- Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in LiberiaCompletedPhase 4Centers for Disease Control and PreventionNCT06300970Written as Artemether+Lumefantrine (AL)
- Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During PregnancyCompletedPhase 4EpicentreNCT00495508Written as artemether / lumefantrine
- Longitudinal Antimalarial Combinations in UgandaCompletedPhase 3University of California, San FranciscoNCT00123552Written as Artemether+Lumefantrine
- Lumefantrine in Venous Plasma Versus Dried Capillary Blood SpotCompletedPhase 4Thierry BuclinNCT02742285Written as Artemether + lumefantrine
- A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine TetraphosphateCompletedPhase 1GlaxoSmithKlineNCT02184637Written as Artemether + Lumefantrine
- A Phase 1/2a Study of LON002 in Subjects With Advanced Solid TumoursStatus unknownPhase 1/2LondonPharma Ltd.NCT02263950Written as Artemether
- Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated MalariaCompletedPhase 3Universiteit AntwerpenNCT01374581Written as Artemether/Lumefantrine
- Pharmacology of Antimalarial Therapy With or Without Antiretroviral TherapyTerminatedPhase 4International Maternal Pediatric Adolescent AIDS Clinical Trials GroupNCT01728961Written as Artemether/Lumefantrine (AL)
- Parasite Clearance Time and Time to Recurrent Infection Following Treatment With Artemether/LumefantrineCompletedPhase 4Muhimbili University of Health and Allied SciencesNCT01998295Written as Artemether/lumefantrine
- Interaction Between Etravirine or Darunavir/Ritonavir and Artemether / LumefantrineCompletedPhase 1Janssen Pharmaceutica N.V., BelgiumNCT01876966Written as artemether/lumefantrine
- Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug CombinationsCompletedPhase 1Fran AweekaNCT00697892Written as artemether/lumefantrine
- Drug Interaction Study Between Antimalarial and Anti-HIV MedicationsCompletedPhase 1University of California, San FranciscoNCT00266058Written as Lopinavir/Ritonavir, Efavirenz, Artemether/lumefantrine
- Efficacy of ArTiMist™ in ChildrenCompletedPhase 2Proto Pharma LtdNCT01047436Written as Artemether
- Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected AdultsCompletedPhase 4University of Cape TownNCT00790881Written as Artemether/Lumefantrine
- Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected AdultsCompletedPhase 4University of Cape TownNCT00869700Written as Artemether/Lumefantrine
- Ototoxicity of Artemether / Lumefantrine (Coartem) and Other AntimalarialsCompletedPhase 4Jimma UniversityNCT00451139Written as artemether/lumefantrine
Given in every arm · 6 — Artemether is usual care beside what is tested
- Investigating the Pharmacology of Tafenoquine in Papua New Guinean Children With Uncomplicated MalariaNot yet recruitingPhase 4Curtin UniversityNCT07403643Written as Artemether + Lumefantrine
- A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)CompletedPhase 1Merck Sharp & Dohme LLCNCT06294912Written as Artemether/lumefantrine
- Study of Malaria Vaccine RTS,S/AS01E in Plasmodium Falciparum-infected and Uninfected Adults Pre-treated With Anti-malarial TherapyCompletedPhase 2PATHNCT04661579Written as Artemether / Lumefantrine
- Ivermectin-artemisinin Combination Therapy for Eradication of MalariaStatus unknownPhase 4Makerere UniversityNCT05605925Written as Artemether/lumefantrine
- Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in MaliCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT03510481Written as artemether 20mg/lumefantrine 120mg (AL)
- Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy SubjectsCompletedPhase 1Idorsia Pharmaceuticals Ltd.NCT02223871Written as Artemether 20 mg and lumefantrine 120mg combination tablet:
As the comparator · 3 — what is tested is compared with Artemether
- Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-LumefantrineCompletedPhase 2/3University of IbadanNCT05192265Written as Antimalarials, Artemether + Lumefantrine
- Antioxidant Micronutrients in MalariaCompletedPhase 3University of Lagos, NigeriaNCT01152931Written as Lumefantrine + Artemether
- Randomised Efficacy Study of Two Artemether-Lumefantrine Oral Formulations for the Treatment of Uncomplicated P. Falciparum MalariaCompletedPhase 4Dafra PharmaNCT00529867Written as Artemether/lumefantrine tablets
Codes
What other systems call Artemether · ClinicalTrials.gg INT006745
- MeSH (NLM) D000077549ArtemetherConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) C7D6T3H22JARTEMETHERConfirmed FDA, NLM, Wikidata
- RxNorm 18343Confirmed FDA, Wikidata
- Wikidata Q416199artemetherConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C73001ArtemetherOne source FDA
- DrugBank DB06697One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077549 | Artemether | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | C7D6T3H22J | ARTEMETHER | Confirmed FDA, NLM, Wikidata |
| RxNorm | 18343 | — | Confirmed FDA, Wikidata |
| Wikidata | Q416199 | artemether | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C73001 | Artemether | One source FDA |
| DrugBank | DB06697 | — | One source Wikidata |
Also registered as .alpha.-artemether (UNII 111W6L37CC).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.