Drug
Soticlestat clinical trials
Also written TAK-935.
- studies test it
- 20
- open now
- 0
- in phase 3
- 4
- first study started
- 2014
How studies write it
Studies that test it under each name
Name
Studies by the year they started
20 studies that test it; most in 2021 (4)
| Year | Studies |
|---|---|
| 2014 | 1 |
| 2015 | 2 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 3 |
| 2019 | 1 |
| 2020 | 2 |
| 2021 | 4 |
| 2022 | 4 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 12
- Phase 2
- 5
- Phase 3
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 20 · Other 0
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses soticlestat is read from its arms, and is right about nine times in ten.
Testing it · 20
- A Study of Soticlestat in Healthy Adult Nondependent Recreational Drug Users With Central Nervous System (CNS) Depressant ExperienceCompletedPhase 1TakedaNCT05602818Written as Soticlestat 300 mg
- A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single Ascending Dose and Multiple Doses With Titration of TAK-935 in Healthy Japanese ParticipantsCompletedPhase 1TakedaNCT04461483Written as TAK-935
- A Phase 1 Positron Emission Tomography Study to Measure Cholesterol 24S-Hydroxylase Target Occupancy of TAK-935CompletedPhase 1TakedaNCT02497235Written as TAK-935
- TAK-935 Multiple Rising Dose Study in Healthy ParticipantsCompletedPhase 1TakedaNCT02539134Written as TAK-935
- Safety, Tolerability, and Pharmacokinetics of Escalating Single Doses of TAK-935CompletedPhase 1TakedaNCT02201056Written as TAK-935
- A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver FunctionCompletedPhase 1TakedaNCT05098054Written as Soticlestat
- A Study to Determine the Bioavailability and Food Effect of a Single TAK-935 Dose in Healthy ParticipantsCompletedPhase 1TakedaNCT02906813Written as TAK-935 Tablets
- A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic EncephalopathiesCompletedPhase 2TakedaNCT03650452Written as TAK-935
- Study of TAK-935 as an Adjunctive Therapy in Participants With Developmental and/or Epileptic EncephalopathiesCompletedPhase 1/2TakedaNCT03166215Written as TAK-935
- Study of TAK-935 as an Adjunctive Therapy in Adult Participants With Complex Regional Pain Syndrome (CRPS)CompletedPhase 2Millennium Pharmaceuticals, Inc.NCT03990649Written as Soticlestat
- Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male ParticipantsCompletedPhase 1TakedaNCT04992442Written as TAK-935 Oral Tablet
- A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut SyndromeCompletedPhase 3TakedaNCT04938427Written as Soticlestat
- A Study of Soticlestat Tablets in Healthy AdultsCompletedPhase 1TakedaNCT05284760Written as Soticlestat
- A Study of Soticlestat and Rifampin in Healthy AdultsCompletedPhase 1TakedaNCT05098041Written as Soticlestat
- A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)CompletedPhase 2TakedaNCT03694275Written as Soticlestat
- A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet SyndromeCompletedPhase 3TakedaNCT04940624Written as Soticlestat
- A Study of Soticlestat in Adults and Children With Rare EpilepsiesTerminatedPhase 2TakedaNCT03635073Written as Soticlestat
- A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut SyndromeTerminatedPhase 3TakedaNCT05163314Written as Soticlestat
- A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to FenfluramineTerminatedPhase 3TakedaNCT06422377Written as Soticlestat
- A Study of Soticlestat in Healthy Adults To Evaluate the Effect on QTc IntervalWithdrawnPhase 1TakedaNCT05309902Written as Soticlestat
Given in every arm · 1 — soticlestat is usual care beside what is tested
Codes
What other systems call soticlestat · ClinicalTrials.gg INT001520
- MeSH (NLM) C000712808soticlestatConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 1766MU795LSOTICLESTATConfirmed FDA, NLM
- NCI Thesaurus C166470SoticlestatOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000712808 | soticlestat | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 1766MU795L | SOTICLESTAT | Confirmed FDA, NLM |
| NCI Thesaurus | C166470 | Soticlestat | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.