Drug
Silymarin clinical trials
- studies test it
- 44
- open now
- 9
- in phase 3
- 11
- first study started
- 2000
Keep track of what changes. Save the Silymarin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
44 studies that test it; most in 2022 (4)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2001 | 2 |
| 2003 | 2 |
| 2005 | 1 |
| 2006 | 2 |
| 2008 | 3 |
| 2009 | 2 |
| 2010 | 3 |
| 2011 | 1 |
| 2012 | 3 |
| 2013 | 1 |
| 2016 | 2 |
| 2019 | 3 |
| 2020 | 1 |
| 2021 | 2 |
| 2022 | 4 |
| 2023 | 2 |
| 2024 | 3 |
| 2025 | 4 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 7
- Phase 2
- 17
- Phase 3
- 11
- Phase 4
- 7
- No phase
- 8
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 42
Tanta University (6) · National Center for Complementary and Integrative Health (NCCIH) (4) · University of Maryland, Baltimore (2) · Isfahan University of Medical Sciences (2) · Assiut University (2) · University of Mosul (1) · University of Novi Sad (1) · Lahore General Hospital (1)
Often tested with
Tested in the same studies.
Ursodeoxycholic Acid (1) · Antioxidants (1) · Colchicine (1) · Green Tea Extract (1) · Silybin (1) · Vitamin E (1) · Fenofibrate (1) · Acetylcysteine (1)
Studies
Open first, then newest update. How each study uses Silymarin is read from its arms, and is right about nine times in ten.
Testing it · 44
- Vitamin E Versus Silymarin in Non Diabetic MASLD PatientsNot yet recruitingPhase 3Kafrelsheikh UniversityNCT07863648Written as Silymarin 420 mg
- Clinical Study Evaluating the Efficacy and Safety of Fenofibrates Versus Silymarin in Adult Patients With SepsisNot yet recruitingPhase 2Tanta UniversityNCT07572552Written as Silymarin
- Silymarin vs Hesperidin/Diosmin in FibromyalgiaRecruitingNot applicableAin Shams UniversityNCT07293767Written as Silymarin (LEGALON)
- Role of Silymarin in Neuroprotection and Symptom Management in Parkinson's DiseaseRecruitingPhase 2Tanta UniversityNCT07001150Written as Silymarin
- Effect of Silymarin as Add on Therapy on Oxidative Stress, Pulmonary Function and Quality of Life in Stable COPD Patients.Enrolling by invitationNot applicableBangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshNCT07123922Written as Silymarin
- Comparison of the Outcome of Treatment With Silymarin or N-Aceylcysteine in Patients Taking Anti-Tuberculous Drugs for Tuberculosis at a Tertiary Care Hospital , KarachiNot yet recruitingPhase 1Liaquat National Hospital & Medical CollegeNCT07058090Written as Silymarin 420 mg
- Beneficial Effect of Silymarin in Ulcerative ColitisRecruitingPhase 2Tanta UniversityNCT06213857Written as Silymarin
- Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic DiseasesRecruitingNot applicablePhramongkutklao College of Medicine and HospitalNCT06277635Written as Silymarin
- Effect of Silymarin in Metastatic Colorectal Cancer PatientsRecruitingPhase 3Tanta UniversityNCT05631041Written as Silymarin
- Silymarin Effects on Fatty Liver in Type 2 DiabeticsCompletedNot applicableUniversity of MosulNCT07871370Written as Silymarin (Silybum marianum)
- Silymarin for the Prevention of Atrial Fibrillation After Cardiac SurgeryCompletedPhase 3University of Novi SadNCT06114719Written as Silymarin
- Impact of Silymarin Adjunct Therapy on Proteinuria in Type 2 Diabetic Patients on RAS InhibitorsCompletedPhase 2Lahore General HospitalNCT06425705Written as Silymarin
- Comparison Between Isotretinoin, Silymarin and Both in the Treatment of Acne VulgarisStatus unknownPhase 4Tanta UniversityNCT05666765Written as Isotretinoin ,silymarin
- Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer PatientsStatus unknownPhase 2/3Tanta UniversityNCT05595109Written as Silymarin
- Silymarin in COVID-19 Patients Admitted to Hospital With Elevated Liver EnzymesCompletedPhase 4F.D. Roosevelt Teaching Hospital with Policlinic Banska BystricaNCT04816682Written as Silymarin
- Efficacy of Silymarin in Patients With Non-alcoholic Fatty Liver Disease - The SILIVER TrialStatus unknownNot applicableCamila Ribeiro de AvelarNCT03749070Written as Silymarin
- Silymarin Cream Versus Combined Silymarin Cream and Microneedling in Treatment of MelasmaStatus unknownPhase 4Assiut UniversityNCT05099601Written as Silymarin
- Efficacy of Silymarin for Acute HepatitisCompletedPhase 4University of Maryland, BaltimoreNCT00412763Written as Silymarin (Silybum marianum)
- Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral HepatitisTerminatedPhase 2/3University of Maryland, BaltimoreNCT00755950Written as Silymarin
- Silymarin Cream Versus Salicylic Acid in Treatment of Acne VulgarisStatus unknownPhase 4Assiut UniversityNCT04490967Written as Silymarin
See all 44 studies that test Silymarin →
Given in every arm · 2 — Silymarin is usual care beside what is tested
- Misocholic Tablets for Non-Viral Elevated Liver EnzymesNot yet recruitingPhase 3Hanoi Medical UniversityNCT07833514Written as Silymarin (Silybum marianum)
- Glucocorticoids for Acute Drug Induced Liver Injury With HyperbilirubinemiaRecruitingNot applicableGeneral Hospital of Shenyang Military RegionNCT06922669Written as Silymarin
As the comparator · 3 — what is tested is compared with Silymarin
- The Efficacy and Safety of Ornithine Aspartic Acid Granules in NAFLD Against Silymarin CapsulesCompletedPhase 4Xinhua Hospital, Shanghai Jiao Tong University School of MedicineNCT05042245Written as Silymarin capsule
- TONKA Versus Legalon for Lowering Hepatic Enzymes in Liver Function Disorder Patients.Status unknownPhase 3Nhat Nhat Pharmaceutical CompanyNCT03216668Written as LEGALON
- To Evaluate the Efficacy of DDB/Garlic Oil in Patients With Elevated Transaminase Chronic Liver DiseaseCompletedPhase 4PharmaKingNCT02347319Written as Legalon
Codes
What other systems call Silymarin · ClinicalTrials.gg INT008202
- MeSH (NLM) D012838SilymarinOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D012838 | Silymarin | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.