DrugBiological

Siltuximab clinical trials

Also written CNTO 328 and Sylvant.

studies test it: 39
open now: 8
in phase 3: 3
first study started: 2003

Keep track of what changes. Save the siltuximab studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.

Watch these studies

How studies write it

Studies that test it under each name

Studies by the year they started

38 studies that test it; most in 2011 (4)

Studies that test siltuximab, by start year
Year	Studies
2003	1
2005	2
2006	3
2007	1
2008	1
2009	2
2010	2
2011	4
2012	2
2016	3
2017	1
2020	4
2021	2
2023	4
2024	2
2025	4

By phase

A phase 1/2 study counts in both.

Early Phase 1: 3
Phase 1: 14
Phase 2: 24
Phase 3: 3

What it is tested for

Each study’s main condition, where its own words name it.

Multiple Myeloma: 11
Lymphoma, Non-Hodgkin: 3
Castleman Disease: 3
Prostatic Neoplasms: 3
Cytokine Release Syndrome: 2
COVID-19: 2
Carcinoma, Renal Cell: 2
Pancreatic Neoplasms: 1
Diabetes Mellitus, Type 1: 1
Neoplasms: 1
Neurilemmoma: 1
Schizophrenia: 1

Who runs them

Industry 18 · Other 21

Centocor, Inc. (8) · Janssen Research & Development, LLC (7) · Memorial Sloan Kettering Cancer Center (2) · SWOG Cancer Research Network (2) · Recordati UK (2) · University of Alabama at Birmingham (1) · Emory University (1) · Timothy Voorhees (1)

Often tested with

Tested in the same studies.

Bortezomib (2) · Dexamethasone (2) · Spartalizumab (1) · Interleukin 1 Receptor Antagonist Protein (1) · Tocilizumab (1) · Lenalidomide (1) · Docetaxel (1) · Anti-IL-6 Monoclonal Antibody (1)

Studies

Open first, then newest update. How each study uses siltuximab is read from its arms, and is right about nine times in ten.

Testing it · 39

See all 39 studies that test siltuximab →

Given in every arm · 3 — siltuximab is usual care beside what is tested

Codes

What other systems call siltuximab · ClinicalTrials.gg INT004818

MeSH (NLM) C504234siltuximabConfirmed ClinicalTrials.gov, NLM, Wikidata
UNII (FDA) T4H8FMA7IMSILTUXIMABConfirmed FDA, NLM, Wikidata
RxNorm 1535218Confirmed FDA, Wikidata
Wikidata Q3960572siltuximabConfirmed FDA, NLM, Wikidata
NCI Thesaurus C61084SiltuximabOne source FDA
DrugBank DB09036One source Wikidata

System	Code	Name there	Checked by
MeSH (NLM)	C504234	siltuximab	Confirmed ClinicalTrials.gov, NLM, Wikidata
UNII (FDA)	T4H8FMA7IM	SILTUXIMAB	Confirmed FDA, NLM, Wikidata
RxNorm	1535218	—	Confirmed FDA, Wikidata
Wikidata	Q3960572	siltuximab	Confirmed FDA, NLM, Wikidata
NCI Thesaurus	C61084	Siltuximab	One source FDA
DrugBank	DB09036	—	One source Wikidata

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.