Serotonin Receptor Agonists: all 773 studies that test it

Page 3 of 8. Open to participants first (148), then studies with results posted, then the rest; newest registration first within each.

• A Study of Lasmiditan and Propranolol in Healthy ParticipantsCompletedNCT03270644Phase 1Results posted
• Effect of Lorcaserin on Cannabis Withdrawal and Self-administrationCompletedNCT03253926Phase 1/2Results posted
• A Study of Multiple Doses of Lasmiditan in Healthy ParticipantsCompletedNCT03252015Phase 1Results posted
• A Study of Lasmiditan in Participants With MigraineCompletedNCT03247790Phase 1Results posted
• Treatment With Lorcaserin for Cocaine Use: The TLC StudyTerminatedNCT03192995Phase 2Results posted
• A Study of Lasmiditan in Healthy ParticipantsCompletedNCT03182920Phase 1Results posted
• Effects of Psilocybin in Major Depressive DisorderCompletedNCT03181529Phase 2Results posted
• A Study to Evaluate the Effect of the Potent Cytochrome P-450 3A4 (CYP3A4) Inhibitor Itraconazole on the Pharmacokinetics (PK) of TAK-954 in Healthy Adult ParticipantsCompletedNCT03173170Phase 1Results posted
• Lorcaserin in Combination With XR-Naltrexone for Relapse Prevention in Opioid Use DisorderCompletedNCT03169816Phase 2/3Results posted
• Drug Interaction and Subjective Effects of Compounds for Opioid Use DisorderCompletedNCT03143855Phase 1Results posted
• Effect of Single Oral Doses of Lasmiditan When Coadministered With Single Oral Doses of Sumatriptan in Healthy ParticipantsCompletedNCT03076970Phase 1Results posted
• Pharmacokinetic Single Dose Study of Oral Lasmiditan in Participants With Normal and Impaired Hepatic FunctionCompletedNCT03040479Phase 1Results posted
• Absorption, Metabolism and Excretion of [14C]-Lasmiditan - Single Oral Dose AdministrationCompletedNCT03040362Phase 1Results posted
• The Effects of Lasmiditan on Simulated Driving Performance - Healthy ParticipantsCompletedNCT03012334Phase 1Results posted
• Study of Oral Lasmiditan in Participants With Normal and Impaired Renal FunctionCompletedNCT03009162Phase 1Results posted
• Lorcaserin in the Treatment of Cocaine Use DisorderCompletedNCT03007394Phase 2Results posted
• Persisting Effects of PsilocybinCompletedNCT02971605Phase 1/2Results posted
• Psilocybin-assisted Group Therapy for Demoralization in Long-term AIDS SurvivorsCompletedNCT02950467Phase 1Results posted
• Combination Nicotine Patch / Lorcaserin for Smoking CessationCompletedNCT02906644Phase 2Results posted
• An Efficacy and Safety Study of DFN-02 (Sumatriptan Nasal Spray 10 mg)CompletedNCT02856802Phase 2Results posted
• Buspirone in Parkinson's DiseaseCompletedNCT02803749Phase 2Results posted
• MEtformin and Lorcaserin for WeighT Loss in SchizophreniaTerminatedNCT02796144Phase 4Results posted
• Buspirone for Functional DysphagiaCompletedNCT02674412Not applicableResults posted
• Three Doses of Lasmiditan (50 mg, 100 mg and 200 mg) Compared to Placebo in the Acute Treatment of MigraineCompletedNCT02605174Phase 3Results posted
• Pilot Study of DFN-11 Injection in Medication Overuse HeadacheTerminatedNCT02583425Phase 2Results posted
• Pilot Study of Two Different Strengths of DFN-11 Injection for Rapidly Escalating MigraineCompletedNCT02571049Phase 2Results posted
• DFN-11 Injection in Episodic Migraine With or Without AuraCompletedNCT02569853Phase 3Results posted
• An Open-label, Long-term, Safety Study of Lasmiditan for the Acute Treatment of MigraineCompletedNCT02565186Phase 3Results posted
• Evaluating Muscle Weakness Improvement With Lorcaserin in ICUTerminatedNCT02523690Phase 1/2Results posted
• Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCICompletedNCT02458469Phase 2Results posted
• Rizatriptan for Episodic Dizziness in Vestibular MigraineCompletedNCT02447991Phase 2/3Results posted
• Lasmiditan Compared to Placebo in the Acute Treatment of Migraine:CompletedNCT02439320Phase 3Results posted
• A Study of Vilazodone in Pediatric Patients With Major Depressive DisorderCompletedNCT02436239Phase 3Results posted
• Addressing Post Cessation Weight GainTerminatedNCT02412631Phase 2/3Results posted
• Lorcaserin for Preventing Weight Gain Among SmokersCompletedNCT02393547Phase 1/2Results posted
• Lifestyle Modification and Lorcaserin for Weight Loss MaintenanceCompletedNCT02388568Not applicableResults posted
• Safety and Efficacy of Vilazodone in Pediatric Patients With Major Depressive Disorder (VLZ-MD-22)CompletedNCT02372799Phase 3Results posted
• Long Term Effect of Buspirone on Esophageal Function and Esophageal Symptoms in Patients With Systematic Sclerosis (SSc)CompletedNCT02363478Early Phase 1Results posted
• Food-Effect Study in Healthy ParticipantsCompletedNCT02233296Phase 1Results posted
• Buspirone, Stress, and Attentional Bias to Marijuana CuesCompletedNCT02132832Phase 2Results posted
• Low Level Laser Treatment (LLLT) and Lorcaserin for Weight ManagementCompletedNCT02129608Phase 3Results posted
• Phase 1 Safety Study of Dimethyl Sulfoxide Cryopreserved PlateletsCompletedNCT02078284Phase 1Results posted
• A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol DependenceCompletedNCT02061293Phase 2Results posted
• A Study to Evaluate the Effect of Lorcaserin Hydrochloride on Smoking CessationCompletedNCT02044874Phase 2Results posted
• Psilocybin-facilitated Treatment for Cocaine UseCompletedNCT02037126Phase 2Results posted
• A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk FactorsCompletedNCT02019264Phase 4Results posted
• Switching From Generic Selective Serotonin Reuptake Inhibitors (SSRIs) and Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) to Three Different Dose Initiation Strategies With VilazodoneCompletedNCT02015546Phase 3Results posted
• Vilazodone for Separation Anxiety DisorderCompletedNCT01999920Phase 4Results posted
• A Multicenter, Double-blind, Randomized, Parallel-group, Pilot Study of 12-week Duration to Assess the Short-term Safety and Tolerability of Lorcaserin Plus Two Doses of Immediate-Release Phentermine-HCl Compared With Lorcaserin Alone in Overweight and Obese AdultsCompletedNCT01987427Phase 4Results posted
• A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding IntoleranceCompletedNCT01953081Phase 1/2Results posted
• Safety and Efficacy of Vilazodone in Adolescent Patients With Major Depressive DisorderCompletedNCT01878292Phase 3Results posted
• Sumatriptan as Treatment for Post-traumatic HeadacheCompletedNCT01854385Phase 2Results posted
• An Open-Label Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum DisordersCompletedNCT01850355Not applicableResults posted
• Safety, Efficacy and Tolerability of Vilazodone in (GAD) Generalized Anxiety DisorderCompletedNCT01844115Phase 3Results posted
• Vilazodone for Corticosteroid-Induced Memory ImpairmentCompletedNCT01828515Phase 2Results posted
• Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and AggressionCompletedNCT01821690Phase 4Results posted
• Comparison of Ketorolac Nasal Spray to Sumatriptan Nasal Spray and Placebo for Acute Treatment of MigraineCompletedNCT01807234Phase 4Results posted
• Double-Blind Treatment of Major Depressive Disorder With VilazodoneCompletedNCT01742832Phase 2Results posted
• Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon ActivityCompletedNCT01707667Phase 4Results posted
• Vilazodone for Menopausal Hot FlashesCompletedNCT01680900Not applicableResults posted
• A Phase 1, Multiple Intravenous Dose Study to Examine Safety, Tolerability, and PK of Intravenous TD-8954, a 5-HT4 Receptor Agonist, in Healthy SubjectsTerminatedNCT01644240Phase 1Results posted
• Study of Buspirone for Relapse-Prevention in Adults With Cocaine DependenceCompletedNCT01641159Phase 2Results posted
• Impact of Buspirone Maintenance on the Reinforcing Effects of CocaineCompletedNCT01639157Not applicableResults posted
• Safety, Efficacy and Tolerability of Vilazodone in Generalized Anxiety DisorderCompletedNCT01629966Phase 3Results posted
• Vilazodone for Treatment of Geriatric DepressionCompletedNCT01608295Phase 4Results posted
• Vilazodone Treatment for Marijuana DependenceCompletedNCT01574183Phase 2Results posted
• Effects and Therapeutic Potential of Psilocybin in Alcohol DependenceCompletedNCT01534494Phase 2Results posted
• Buspirone Therapy for Localized EpilepsyTerminatedNCT01496612Phase 2Results posted
• Safety, Efficacy, and Tolerability of Vilazodone in Major Depressive DisorderCompletedNCT01473394Phase 4Results posted
• Safety and Efficacy of Vilazodone in Major Depressive DisorderCompletedNCT01473381Phase 4Results posted
• Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)CompletedNCT01472939Phase 2Results posted
• Safety & Efficacy of a Single Dose of Sumatriptan Powder Delivered Intranasally With the Bi-directional Device in Adults With Acute MigraineCompletedNCT01462812Phase 3Results posted
• Evaluation of Long-term Prucalopride Treatment With Chronic Constipation in Subjects Aged ≥ 18 YearsCompletedNCT01424228Phase 4Results posted
• SSP-002358 Drug Interaction Study With OmeprazoleCompletedNCT01415349Phase 1Results posted
• An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD PatientsTerminatedNCT01370863Phase 2Results posted
• Prucalopride in Pediatric Subjects With Functional ConstipationCompletedNCT01330381Phase 3Results posted
• CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After TreximetCompletedNCT01329562Phase 4Results posted
• Treximet Trademark (TM) in the Prevention and Modification of Disease Progression in MigraineCompletedNCT01300546Phase 4Results posted
• Long-Term Exposure to Rizatriptan 5-mg and 10-mg Oral Tablet (Combined Extension Protocols MK-0462-022, MK-0462-025, MK-0462-029)CompletedNCT01286207Phase 3Results posted
• Psychopharmacology for Cocaine Dependence - BuspironeCompletedNCT01267292Phase 2Results posted
• Zomig - Treatment of Acute Migraine Headache in AdolescentsCompletedNCT01211145Phase 4Results posted
• Evaluation of Prucalopride in Male Subjects With Chronic Constipation.CompletedNCT01147926Phase 3Results posted
• Ictal and Interictal Inflammatory Markers in MigraineCompletedNCT01138150Phase 4Results posted
• Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced ConstipationTerminatedNCT01117051Phase 3Results posted
• Treximet in the Treatment of Chronic MigraineCompletedNCT01090050Phase 4Results posted
• Does Treximet Improve Productivity and Patient Satisfaction Due to Sustained Response and Consistency of Response?CompletedNCT01086358Phase 4Results posted
• Trial of Comprehensive Migraine InterventionCompletedNCT01071317Phase 4Results posted
• Treximet for Prevention of Post Traumatic Headache Associated With Cognitive DysfunctionTerminatedNCT01053507Phase 4Results posted
• Evaluation of Treatment Satisfaction and Preference for Sumavel DosePro in the Treatment of MigraineCompletedNCT01016834Phase 4Results posted
• Treximet Early Intervention Adolescent MigraineCompletedNCT01016678Phase 2/3Results posted
• A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Treatment of Acute Migraine in Children and Adolescents (MK-0462-086 AM3)CompletedNCT01004263Phase 3Results posted
• A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine in Children and Adolescents (MK-0462-082 AM7)CompletedNCT01001234Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Oral Sumatriptan for the Acute Treatment of Migraine in Children and AdolescentsCompletedNCT00963937Phase 3Results posted
• Psilocybin Cancer Anxiety StudyCompletedNCT00957359Early Phase 1Results posted
• Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related AnxietyCompletedNCT00920387Phase 2Results posted
• Treatment of Multiple Attacks of Acute Migraine (0462-025)CompletedNCT00899379Phase 3Results posted
• Rizatriptan 5 mg and 10 mg, Sumatriptan 100 mg, and Placebo Comparison Study (0462-030)CompletedNCT00898677Phase 3Results posted
• MK0462 in Treatment of Migraine With Recurrence (MK0462-022)CompletedNCT00897949Phase 3Results posted
• MK0462 5 mg, Sumatriptan 50 mg, and Placebo Comparison Study (0462-029)CompletedNCT00897104Phase 3Results posted
• Dose-ranging Study of APD405 in Post-operative Nausea and Vomiting (PONV)CompletedNCT00895830Phase 2Results posted

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