Serotonin Receptor Agonists: all 773 studies that test it

Page 2 of 8. Open to participants first (148), then studies with results posted, then the rest; newest registration first within each.

• Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)RecruitingNCT06518720Phase 2
• Zuojin Wan Combined With Rabeprazole or Mosapride for the Treatment of Functional Dyspepsia Combined With DepressionNot yet recruitingNCT06481371Not applicable
• Prucalopride for Cognitive Functioning in SchizophreniaNot yet recruitingNCT06474286Not applicable
• A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine HeadacheRecruitingNCT06473597Phase 4
• Psychedelic-assisted Group Program for First RespondersRecruitingNCT06471959Phase 1/2
• Mechanistic Studies of Psilocybin in Headache DisordersRecruitingNCT06464367Early Phase 1
• Psilocybin Therapy for Depression in Parkinson's DiseaseRecruitingNCT06455293Phase 2
• Psilocybin-assisted Therapy for Alcohol Use DisorderNot yet recruitingNCT06444243Phase 2
• Open-Label Psilocybin Study in Transdiagnostic PopulationRecruitingNCT06442423Phase 1
• Study of Psilocybin Assisted Psychotherapy to Address Fear of RecurrenceRecruitingNCT06430541Phase 1
• Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator TrialRecruitingNCT06405607Phase 2
• Study of Psilocybin for Anorexia in Young AdultsRecruitingNCT06399263Phase 2
• Psilocybin for Hospitalized Patients with Treatment-resistant DepressionRecruitingNCT06378229Phase 2
• The Impact of Psilocybin on Pain in Fibromyalgia PatientsRecruitingNCT06368492Not applicable
• Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older AdultsRecruitingNCT06367738Phase 1
• Psilocybin in Chronic Low Back Pain and DepressionRecruitingNCT06355414Phase 1
• Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUDRecruitingNCT06349083Phase 2
• Cancer Related Major Depression Treated With a Single Dose of PsilocybinRecruitingNCT06319378Phase 2
• The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive DisorderRecruitingNCT06247839Phase 3
• Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance TherapyRecruitingNCT06200155Phase 2
• Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)RecruitingNCT06160284Phase 1
• Psilocybin-Assisted Therapy for Severe Alcohol Use DisorderRecruitingNCT06160232Phase 2
• Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSDNot yet recruitingNCT06141876Phase 2
• Psilocybin rTMS for Treatment Resistant DepressionRecruitingNCT06132178Phase 2
• A Randomized Neuroimaging Trial of Psilocybin in DepressionRecruitingNCT06072898Phase 2
• Outpatient Buprenorphine Induction With Psilocybin for Opioid Use DisorderRecruitingNCT06067737Phase 2
• Psilocybin-Assisted Psychotherapy for Alcohol Use DisorderRecruitingNCT05995769Phase 2
• Lysergic Acid Diethylamide (LSD) in Palliative CareRecruitingNCT05883540Phase 2
• Evaluation of Psilocybin-assisted Psychotherapy (PaP) for the Treatment of Post-traumatic Stress Disorder (PTSD) in Military VeteransNot yet recruitingNCT05876481Phase 2
• Buspirone for Weak or Absent Esophageal PeristalsisRecruitingNCT05629325Phase 4
• Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid MedicationRecruitingNCT05585229Phase 2
• The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy TrainingEnrolling by invitationNCT05570708Not applicable
• Evaluating Buspirone to Treat Opioid WithdrawalRecruitingNCT05511909Phase 2
• LSD to Improve Cluster Headache Impact TrialRecruitingNCT05477459Phase 2
• LSD Treatment for Persons With Alcohol Use DisorderRecruitingNCT05474989Phase 2
• Gastrointestinal Dysmotility on Aspiration RiskRecruitingNCT05455359Phase 4
• 5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use DisorderRecruitingNCT05452772Phase 2
• Pragmatic Trial of Psilocybin Therapy in Palliative CareRecruitingNCT05403086Phase 2
• Psilocybin Versus Ketamine in Treatment-Resistant DepressionRecruitingNCT05383313Phase 2
• Effects of Psilocybin on Electrophysiology and the Dynamic Content of ThoughtRecruitingNCT05301608Phase 1/2
• Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the BrainRecruitingNCT05265546Phase 1
• Psilocybin-facilitated Treatment for Chronic PainRecruitingNCT05068791Early Phase 1
• Northwest Therapies Trauma Psilocybin Study Compassionate Use StudyNot yet recruitingNCT05042466Phase 1
• Buspirone and Melatonin for Depression Following Traumatic Brain InjuryRecruitingNCT04400266Phase 4
• Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's DiseaseRecruitingNCT04123314Early Phase 1
• Central Sleep Apnea : Physiologic Mechanisms to Inform TreatmentRecruitingNCT04118387Phase 4
• Measurement of the Hippocampal Theta Rhythm From the Outer Ear CanalRecruitingNCT03954483Not applicable
• Lysergic Acid Diethylamide (LSD) as Treatment for Cluster HeadacheRecruitingNCT03781128Phase 2
• Psilocybin-Assisted Therapy for the Treatment of Cancer-Related Anxiety in Patients With Metastatic CancerCompletedNCT05847686Phase 1/2Results posted
• Different Doses of Naronapride vs. Placebo in GastroparesisCompletedNCT05621811Phase 2Results posted
• A Dose-Finding Study of MM120 (LSD D-Tartrate) for the Treatment of Anxiety SymptomsCompletedNCT05407064Phase 2Results posted
• The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress DisorderCompletedNCT05312151Phase 2Results posted
• Psilocybin-assisted CBT for DepressionCompletedNCT05227612Phase 1Results posted
• Safety and Efficacy of Low Dose MM120 for ADHD Proof of Concept TrialCompletedNCT05200936Phase 2Results posted
• Frontline Clinician Psilocybin StudyCompletedNCT05163496Phase 3Results posted
• Open-label Study to Assess the Safety and Efficacy of Psilocybin With Psychotherapy in Adult Participants With FibromyalgiaCompletedNCT05128162Phase 2Results posted
• Drug-Drug Interaction Study of Evobrutinib and Transporter SubstratesCompletedNCT05064488Phase 1Results posted
• Improving Ventilatory Capacity in Those With Chronic High Level SCICompletedNCT05041322Phase 2Results posted
• Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice CareCompletedNCT04950608Phase 2Results posted
• Psilocybin Therapy for Depression and Anxiety in Parkinson's DiseaseCompletedNCT04932434Phase 2Results posted
• A Study to Compare Two Different Formulations of Lasmiditan in Healthy ParticipantsCompletedNCT04881747Phase 1Results posted
• Buspirone Treatment of Anxiety in Williams SyndromeCompletedNCT04807517Phase 4Results posted
• A Study of Prucalopride For Functional Constipation in Children and TeenagersTerminatedNCT04759833Phase 3Results posted
• A Study of Lasmiditan in Healthy VolunteersCompletedNCT04749914Phase 1Results posted
• The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant DepressionCompletedNCT04739865Phase 2Results posted
• Safety and Efficacy of Psilocybin for Body Dysmorphic DisorderCompletedNCT04656301Phase 2Results posted
• A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet SyndromeTerminatedNCT04572243Phase 3Results posted
• Visual Surround Suppression and Perceptual Expectation Under PsilocybinTerminatedNCT04424225Phase 1Results posted
• Laboratory Screening of Lorcaserin for Alcohol Use DisorderTerminatedNCT04396847Phase 2Results posted
• Mechanisms of Lorcaserin for Smoking CessationTerminatedNCT04396834Phase 2Results posted
• A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With MigraineTerminatedNCT04396574Phase 3Results posted
• A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With MigraineTerminatedNCT04396236Phase 3Results posted
• A Study of Lasmiditan in Healthy Chinese ParticipantsCompletedNCT04081324Phase 1Results posted
• A Study of Lasmiditan (LY573144) in Children Aged 6 to 17 With MigraineCompletedNCT03988088Phase 1Results posted
• A Four-way Crossover Study of 3 Formulations of M207 With Intranasal Zolmitriptan in Healthy VolunteersCompletedNCT03978403Phase 1Results posted
• A Study Lasmiditan (LY573144) in a Single Migraine Attack in Japanese Participants With MigraineCompletedNCT03962738Phase 2Results posted
• Mood Effects of Serotonin Agonists ExtendedCompletedNCT03934710Phase 1Results posted
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of TAK-954 in Healthy Adult ParticipantsCompletedNCT03870555Phase 1Results posted
• A Study of Psilocybin for Major Depressive Disorder (MDD)CompletedNCT03866174Phase 2Results posted
• A Study of TAK-954 to Treat Gastrointestinal Dysfunction in Adults After SurgeryCompletedNCT03827655Phase 2Results posted
• The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant DepressionCompletedNCT03775200Phase 2Results posted
• A Study of Lasmiditan (LY573144) Over Four Migraine AttacksCompletedNCT03670810Phase 3Results posted
• Lorcaserin for Cannabis Use DisorderTerminatedNCT03637842Early Phase 1Results posted
• Buspirone for Early Satiety and Symptoms of GastroparesisCompletedNCT03587142Phase 2Results posted
• A Study of Lasmiditan in Healthy Japanese and Caucasian ParticipantsCompletedNCT03579940Phase 1Results posted
• Improving Driving in Young People With Autism Spectrum DisordersCompletedNCT03538431Phase 4Results posted
• A Study to Evaluate the Mass Balance, Pharmacokinetics (PK), Metabolism and Excretion of TAK-954 Containing Microtracer ([14C]-TAK-954) in Healthy Male ParticipantsCompletedNCT03500224Phase 1Results posted
• TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)TerminatedNCT03477903Phase 2Results posted
• A Study of Lasmiditan on the Heart in Healthy ParticipantsCompletedNCT03465436Phase 1Results posted
• A Study of Lasmiditan on Simulated Driving Performance in Healthy ParticipantsCompletedNCT03459612Phase 1Results posted
• A Study of Lasmiditan in Healthy Elderly ParticipantsCompletedNCT03406260Phase 1Results posted
• Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.CompletedNCT03356483Phase 1Results posted
• Predictors of Lorcaserin-Induced Weight LossTerminatedNCT03353220Phase 4Results posted
• Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Loss in Obese Adolescents, Age 12 to 17 YearsTerminatedNCT03338296Phase 4Results posted
• A Study of Lasmiditan When Given With Sumatriptan in Healthy ParticipantsCompletedNCT03310411Phase 1Results posted
• A Study of Lasmiditan in Healthy Participants When Co-administered With TopiramateCompletedNCT03308669Phase 1Results posted
• A Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics (PK) of a Single Intravenous (IV) TAK-954CompletedNCT03296787Phase 1Results posted
• A Study of the Abuse Potential of Lasmiditan in Participants Who Are Recreational Drug UsersCompletedNCT03286218Phase 1Results posted
• Effect of TAK-954 on Gastrointestinal and Colonic Transit in Diabetic or Idiopathic Gastroparesis ParticipantsCompletedNCT03281577Phase 2Results posted
• A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954CompletedNCT03277274Phase 1Results posted

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