Serotonin Receptor Agonists: all 773 studies that test it

Page 4 of 8. Open to participants first (148), then studies with results posted, then the rest; newest registration first within each.

• A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine (0462-087)CompletedNCT00894556Phase 3Results posted
• "Completeness of Response" Following Treatment With Treximet™ for MigraineCompletedNCT00893737Phase 4Results posted
• Dose-ranging Study of Oral COL-144 in Acute Migraine TreatmentCompletedNCT00883051Phase 2Results posted
• Buspirone Treatment for Marijuana DependenceCompletedNCT00875836Phase 4Results posted
• Sumatriptan Succinate 100 mg Tablets Under Fasting ConditionsCompletedNCT00847405Phase 1Results posted
• Sumatriptan Succinate 100 mg Tablets Under Non-Fasting ConditionsCompletedNCT00846885Phase 1Results posted
• Pilot Study to Compare Frovatriptan vs. Topiramate for Prevention of MigraineCompletedNCT00846495Phase 4Results posted
• Migraine Study in Adolescent PatientsCompletedNCT00843024Phase 3Results posted
• A Study of Rizatriptan for the Treatment of Acute Migraine in Patients on Topiramate for Migraine ProphylaxisCompletedNCT00812006Phase 3Results posted
• An Open-Label Study to Evaluate the Safety of NP101 in the Treatment of Acute Migraine Over Twelve MonthsCompletedNCT00806546Phase 3Results posted
• An Open-Label Study to Evaluate the Safety of NP101 in the Treatment of Acute Migraine Over 12 MonthsCompletedNCT00792103Phase 3Results posted
• Buspirone as a Potential Treatment for Recurrent Central ApneaTerminatedNCT00746954Phase 3Results posted
• Randomized Trial of Mosapride Versus Placebo in the Treatment of Constipation-Predominant Irritable Bowel SyndromeTerminatedNCT00742872Phase 3Results posted
• Open Label Extension Assessing the Tolerability of BCI-024 in Combination With BCI-049 in Patients With Major Depressive Disorder (MDD)CompletedNCT00731653Phase 2Results posted
• The Efficacy and Tolerability of NP101 Patch in the Treatment of Acute MigraineCompletedNCT00724815Phase 3Results posted
• The Effects of Expectation and Knowledge on Rizatriptan and Placebo Treatment of Acute Migraine HeadacheCompletedNCT00719134Phase 4Results posted
• Study to Evaluate the Safety, Tolerability, and Blood Pressure Effect of an Oral Dose of Sumatriptan Alone and in Combination With MK-0974 (Telcagepant) in Migraine Patients (0974-026)CompletedNCT00701389Phase 1Results posted
• Randomized, Double-Blind, Placebo Controlled Study of Vilazodone's Efficacy, Safety, and Biomarkers of Response in Major Depressive Disorder (MDD)CompletedNCT00683592Phase 3Results posted
• A One Year Open Label Study Assessing the Safety and Tolerability of Vilazodone in Patients With Major Depressive Disorder (MDD)CompletedNCT00644358Phase 3Results posted
• Preliminary Study of Piclozotan in Patients With Motor Complications Associated With Parkinson's DiseaseCompletedNCT00623363Phase 2Results posted
• A Study on the Effects of Repeat Doses of Intraject® Sumatriptan on Local Site SignsCompletedNCT00620425Phase 1Results posted
• Drug Study in Pediatric Subjects With Migraines (MK0462-083 AM1)CompletedNCT00604812Phase 1Results posted
• BLOSSOM: Behavioral Modification and Lorcaserin Second Study for Obesity ManagementCompletedNCT00603902Phase 3Results posted
• BLOOM-DM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management in Diabetes MellitusCompletedNCT00603291Phase 3Results posted
• TREXIMET® Versus Butalbital-containing Combination Medications for the Acute Treatment of Migraine in AdultsCompletedNCT00573170Phase 3Results posted
• Study Evaluating Vabicaserin in Subjects With SchizophreniaCompletedNCT00563706Phase 2Results posted
• Study to Test Rizatriptan in the Early Treatment of Acute Migraine (0462-081)CompletedNCT00516737Phase 3Results posted
• Naratriptan for the Treatment of Post Traumatic Headache Associated With Cognitive DysfunctionTerminatedNCT00487578Phase 4Results posted
• Psychopharmacology of Psilocybin in Cancer PatientsCompletedNCT00465595Phase 2Results posted
• Comparing Naproxen to Sumatriptan for Emergency Headache PatientsCompletedNCT00449787Phase 4Results posted
• A Research Study To Evaluate If Frovatriptan Is Safe And Effective In Preventing Migraine Headache After FastingCompletedNCT00440232Not applicableResults posted
• Two Rizatriptan Prescribing Portions for Treatment of MigraineCompletedNCT00397254Phase 4Results posted
• BLOOM: Behavioral Modification and Lorcaserin for Overweight and Obesity ManagementCompletedNCT00395135Phase 3Results posted
• TREXIMET (Formerly Known as TREXIMA) for the Acute Treatment of Probable Migraine (ICHD-II 1.6.1)CompletedNCT00387881Phase 3Results posted
• TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a MigraineCompletedNCT00385008Phase 3Results posted
• A Placebo-Controlled Adaptive Treatment Assignment Study of Intravenous COL-144 in the Acute Treatment of MigraineCompletedNCT00384774Phase 2Results posted
• Does a Migraine Medication Decrease Rotational Motion Sickness in People Suffering From Migraines?CompletedNCT00360282Not applicableResults posted
• Study Of Sumatriptan Succinate Injection Kit In Patients With Migraine or Cluster Headache In JapanCompletedNCT00356603Phase 3Results posted
• Prospective Survey of Menstrual Migraine & Prevention With EletriptanCompletedNCT00259649Phase 4Results posted
• A 1-year Study in Adolescents to Assess the Long-term Safety of Almotriptan Malate When Treating Their Migraine HeadachesCompletedNCT00257010Phase 3Results posted
• Study to Test a Marketed Product in the Treatment of Migraine-associated NauseaCompletedNCT00250458Phase 3Results posted
• Buspirone in Reducing Shortness of Breath in Patients With CancerCompletedNCT00053846Phase 2/3Results posted
• A Study to Assess the Adverse Events and How Bretisilocin Intramuscular Injection Moves Through the Body of Healthy Adult ParticipantsCompletedNCT07604558Phase 1
• Pharmacokinetics and Safety of GH001 Delivered Via a GH001 Aerosol Delivery System in Healthy SubjectsCompletedNCT07540494Phase 1
• Acute Effect of Polyphenols Supplementation on Endothelial Function and Exercise Related Markers, in Physically Active Healthy Volunteers.Active, not recruitingNCT07518758Not applicable
• Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic MalignanciesActive, not recruitingNCT07336238Phase 2
• The Effect of Two Prokinetics in Patients With Functional DyspepsiaActive, not recruitingNCT07096921Not applicable
• Drug Effects on Mood and Behavior - ExpectancyCompletedNCT07061886Early Phase 1
• A Study Assessing Brain Activity, Safety, Tolerability, and Pharmacokinetics Following Multiple Doses of MLS101 (Psilocybin) in Healthy VolunteersCompletedNCT07050368Phase 1
• Mood Effects of Serotonin Agonists: DepressionCompletedNCT07017478Early Phase 1
• A Phase 3 Trial of DT120 for Major Depressive Disorder (Emerge)Active, not recruitingNCT06941844Phase 3
• Acute Effects of MDMA Co-administration on the Response to Psilocybin in Healthy SubjectsCompletedNCT06884514Phase 1
• PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)Active, not recruitingNCT06853912Phase 2
• Safety, Tolerability, and Efficacy of Sublingual Microdoses of 5-MeO-DMT for Depression and AnxietyCompletedNCT06816667Phase 1/2
• Trifecta Research StudyWithdrawnNCT06810765Phase 2
• A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)Active, not recruitingNCT06809595Phase 3
• Effect of Psilocybin Only and Psilocybin Assisted Cognitive Behavioral Therapy in the Management of Major Depressive Disorder and Associated Metabolic, Immune, Inflammatory, Neuroplasticity and Electrical Activity MarkersCompletedNCT06746441Phase 2
• A Phase 3 Trial of DT120 for Generalized Anxiety Disorder (Voyage)Active, not recruitingNCT06741228Phase 3
• Psilocybin for Treatment-Resistant Depression in AutismActive, not recruitingNCT06731621Phase 1
• A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)Active, not recruitingNCT06719141Phase 3
• A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)Active, not recruitingNCT06660394Phase 3
• RE104 Clinical Lactation StudyCompletedNCT06659263Phase 1
• Effect of Psilocybin on the Positive Valence System in Treatment-resistant DepressionCompletedNCT06650800Not applicable
• Evaluation of the Effect of a Single Dose of Psilocybin on Neural Correlates of Cognitive Control in Patients With Psychogenic Nonepileptic SeizuresCompletedNCT06647056Not applicable
• A Second Psilocybin Group Therapy for the Treatment of Cancer-Related Anxiety in Partial Responders With Metastatic CancerCompletedNCT06644170Phase 1
• A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of MLS101 in Healthy ParticipantsCompletedNCT06643637Phase 1
• Nebulized Dexmedetomidine Versus Oral Sumatriptan in Treatment of Post Dural Puncture Headache in Cesarean SectionCompletedNCT06514040Not applicable
• Pharmacokinetics of GH001 Delivered Via a Proprietary Aerosol Delivery Device in Healthy SubjectsTerminatedNCT06511947Phase 1
• Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar DepressionActive, not recruitingNCT06506019Phase 1
• Safety for Home Administration of Microdose Psilocybin UseCompletedNCT06450210Phase 1
• Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced CancerActive, not recruitingNCT06416085Phase 2
• Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSDActive, not recruitingNCT06386003Phase 2
• Low-Income Group Psilocybin Assisted Therapy for DepressionCompletedNCT06372197Not applicable
• RE104 Safety and Efficacy Study in Postpartum DepressionCompletedNCT06342310Phase 2
• A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MLS101 in Healthy ParticipantsCompletedNCT06326606Phase 1
• Psilocybin for Major Depressive Disorder (MDD)Active, not recruitingNCT06308653Phase 3
• Psilocybin-Assisted Therapy in Treatment-Resistant DepressionActive, not recruitingNCT06303739Phase 3
• Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCDCompletedNCT06299319Phase 1
• PsilOCD: A Pharmacological-Challenge Feasibility StudyCompletedNCT06258031Phase 1
• Psilocybin in Alcohol Use Disorder With Comorbid DepressionCompletedNCT06235411Not applicable
• Psilocybin for Treatment-Resistant DepressionCompletedNCT06230757Phase 2
• Safety Profile of Psilocybin for Cocaine Use DisorderSuspendedNCT06102434Early Phase 1
• Safety, Tolerability and Antidepressant Effects of DMT in Patients With DepressionCompletedNCT06094907Phase 2
• Does Serotonin System Stimulation Increase Pro-social Behavior? - A Comparative Pharmacological Neuroscientific Study in Healthy HumansCompletedNCT06081179Phase 1
• Does Psilocybin Change Synaptic Density in Amnestic Mild Cognitive ImpairmentCompletedNCT06041152Phase 2
• Inpatient Buprenorphine Induction With Psilocybin for Opioid Use DisorderWithdrawnNCT06005662Phase 2
• Psilocybin in Cancer Pain StudyActive, not recruitingNCT06001749Phase 2
• LSD-Perceptual-Choice-StudyCompletedNCT05976698Not applicable
• Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy SubjectsCompletedNCT05964647Phase 1
• LSD Occupancy of the Serotonin 2A Receptor in the Human BrainActive, not recruitingNCT05953038Early Phase 1
• Two Doses of Psilocybin for the Treatment of MDD in Adults With CancerActive, not recruitingNCT05947383Phase 2
• Safety and Tolerability of DMT in Healthy AdultsCompletedNCT05901012Phase 1
• Phase 2 Clinical Trial of GH001 in Bipolar II DisorderTerminatedNCT05839509Phase 2
• An Investigation of Psilocybin on Behavioural and Cognitive Symptoms of Adults With Fragile X SyndromeSuspendedNCT05832255Phase 2
• Phase 2 Clinical Trial of GH001 in Postpartum DepressionTerminatedNCT05804708Phase 2
• A Trial of GH001 in Patients With Treatment-resistant DepressionCompletedNCT05800860Phase 2
• Mindfulness and PsychedelicsCompletedNCT05780216Early Phase 1
• Safety and Pharmacokinetics of GH002 in Healthy VolunteersCompletedNCT05753956Phase 1
• A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive DisorderActive, not recruitingNCT05733546Phase 2
• Bowel Preparation Regimen for Colon Capsule Endoscopy ProcedureCompletedNCT05726097Phase 3

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