5-HT3 antagonists: all 422 studies that test it
Page 1 of 5. Open to participants first (39), then studies with results posted, then the rest; newest registration first within each.
- Netupitant/Palonosetron for Prevention of Nausea and Vomiting in Breast Cancer ADC TherapyNot yet recruitingNCT07918079Phase 2
- Effect of Ondansetron on the Incidence of Spinal Anaesthesia-Induced Hypotension in Elderly Patients Undergoing Fracture Hip SurgeryNot yet recruitingNCT07914868Phase 4
- Prophylaxis for Emetogenic radioTherapy With AkynzeoNot yet recruitingNCT07882966Phase 2
- Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial FibrillationRecruitingNCT07877519Not applicable
- Effects of Ondansetron Timing During Spinal Anesthesia for Urologic SurgeryNot yet recruitingNCT07858149Phase 4
- Ondansetron to Prevent Oral Rehydration Failure in Children With CholeraNot yet recruitingNCT07795060Phase 2
- Sleep Quality - Comparing the Effect of Ondansetron or Dexamethasone Given as Routine Prophylaxis Intraoperatively to Prevent Post Operative Nausea and Vomiting (SCORPION)Not yet recruitingNCT07777276Phase 4
- Routine Antiemetic Prophylaxis for Nonfasted Parturients Undergoing Cesarean Sections Under Spinal AnesthesiaRecruitingNCT07740577Phase 4
- A Simplified Regimen to Prevent Nausea and Vomiting Using Netupitant/Palonosetron in Germ Cell Cancer Patients Receiving ChemotherapyNot yet recruitingNCT07662200Early Phase 1
- Time to First Rescue Antiemetic With Ondansetron Plus Metoclopramide Versus Dexamethasone Plus Metoclopramide for PONV Prophylaxis in Laparoscopic CholecystectomyRecruitingNCT07638527Phase 4
- Ondansetron Versus Lidocaine for Preventing Pain on Propofol Injection.Not yet recruitingNCT07632144Not applicable
- Ondansetron for the Prevention of Patient Self-Inflicted Lung Injury in Patients With ARDS - Pilot RCTNot yet recruitingNCT07588217Phase 2/3
- Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Cesarean SectionRecruitingNCT07511491Not applicable
- Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in TonsillectomyRecruitingNCT07489742Not applicable
- The Safety and Efficacy of Ondansetron in Reducing Immune Checkpoint Inhibitor-Related ToxicitiesRecruitingNCT07381634Phase 2
- Post Operative Shivering Following AnesthesiaNot yet recruitingNCT07377903Not applicable
- Granisetron Combined With Dexamethasone or Metoclopramide for PONV Prevention After Laparoscopic CholecystectomyNot yet recruitingNCT07360431Phase 4
- Comparison Between Intravenous Hydrocortisone and Ondansetron in Prevention of Post Spinal Anesthesia HypotensionEnrolling by invitationNCT06930456Not applicable
- Evaluating the Safety and Efficacy of Ondansetron in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography PancreatitisRecruitingNCT06861010Phase 3
- Efficacy of Co-Spinal Ondansetron In Inguinal HerniorrhaphyEnrolling by invitationNCT06850740Not applicable
- Intravenous Granisetron Vs Dexmedetomidine on Postspinal in the Cesarean Section.Enrolling by invitationNCT06762860Not applicable
- Preventative Effect of Combining Dexamethasone with Ondansetron on Postoperative Nausea, Vomiting and Shivering in Children Undergoing Caudal Anesthesia on Hypospadias SurgeryNot yet recruitingNCT06747975Phase 4
- Role of Ondansetron in Spinal Anaesthesia Induced HypotensionNot yet recruitingNCT06727201Phase 2/3
- Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal AnesthesiaRecruitingNCT06444737Not applicable
- Comparative Study Between Intravenous Granisetron and Ondansetron on Their Effect on Hemodynamics and Shivering After Spinal Anesthesia in Elective Cesarean DeliveryRecruitingNCT06437236Not applicable
- Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean SectionRecruitingNCT06297499Phase 1
- Ondansetron (ODF) Versus Ondansetron Intravenously for the Prevention of Chemotherapy-induced Nausea and Vomiting Compare in ChildrenRecruitingNCT06208917Phase 3
- Prevention of Breakthrough CINV in Patients Receiving Moderately or Highly Emetogenic ChemotherapyRecruitingNCT06065722Phase 2
- Clonidine Versus Granisetron for Shivering PrevensionRecruitingNCT06031090Phase 2
- Clinical Trial to Investigate the Efficacy and Safety of Ondansetron (Danset - Adwia) Versus Placebo Plus the Standard of Care in the Treatment of Nausea and Vomiting in Adult Patients With Acute GastroenteritisNot yet recruitingNCT05876585Phase 3
- Ondansetron for the Management of Atrial FibrillationRecruitingNCT05844501Phase 4
- A Proof of Principle Study of Ondansetron for the Prevention of Vasovagal Syncope: The Eleventh Prevention of Syncope Trial (POST11)RecruitingNCT05755737Phase 2
- Aprepitant Plus Granisetron and Dexamethasone for the Prevention of Vomiting in Patients With HAIC Therapy for HCCNot yet recruitingNCT05711823Phase 3
- The Safety and Effectiveness of Palonosetron Hydrochloride Capsule Was Used to CINVRecruitingNCT05690802Not applicable
- Study of Ondansetron in the Prevention of Sleep Syncope: The Nineth Prevention of Syncope Trial (POST9)Not yet recruitingNCT05657925Phase 3
- 5-HT3 Receptor Antagonist (Ramosetron) vs Loperamide for the Treatment of Low Anterior Resection Syndrome(RALARS)RecruitingNCT05577845Not applicable
- 5-HT3 Receptor Antagonist and Respiratory Drive in Patients With ARDSRecruitingNCT05514483Phase 4
- BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to OndansetronRecruitingNCT04150614Phase 4
- Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and DyspepsiaRecruitingNCT03865290Phase 2
- Dexamethasone vs Ondansetron After Cesarean DeliveryCompletedNCT05692245Phase 4Results posted
- SENS-401 to Prevent the Ototoxicity Induced by Cisplatin in Adult Subjects With a Neoplastic DiseaseCompletedNCT05628233Phase 2Results posted
- Ondansetron as a Strategy for Reducing Propofol Injection Pain in Pediatrics: a Randomized Controlled TrialTerminatedNCT05378113Phase 2Results posted
- Evaluation of the Presence of SENS-401 in the PerilymphCompletedNCT05258773Phase 2Results posted
- Haloperidol, Droperidol, Ondansetron in Cannabis HyperemesisTerminatedNCT05065567Phase 3Results posted
- Oral Akynzeo® vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk)CompletedNCT04817189Phase 4Results posted
- PROUD Study - Preventing Opioid Use DisordersTerminatedNCT04766996Phase 4Results posted
- Tariquidar-ondansetron Combination in Neuropathic PainCompletedNCT04603066Phase 1/2Results posted
- A Study of TAK-951 to Stop Adults Getting Nausea and Vomiting After Planned SurgeryCompletedNCT04557189Phase 2Results posted
- Efficacy of SENS 401 in Subjects With Severe or Profound Sudden Sensorineural Hearing LossCompletedNCT03603314Phase 2/3Results posted
- Pharmacogenomics and Post-Operative Nausea and VomitingCompletedNCT03503292Phase 4Results posted
- A Study to Assess the Safety and the Efficacy of IV Fosnetupitant/Palonosetron (260 mg/0.25 mg) Combination Compared to Oral Netupitant/Palonosetron (300 mg/0.5 mg) Combination for the Prevention of CINV in AC Chemotherapy in Women With Breast CancerCompletedNCT03403712Phase 3Results posted
- Treatment of Refractory Nausea and Vomiting in Patients With Breast CancerCompletedNCT03367572Phase 3Results posted
- Effects of Ondansetron Dose and Timing on Post-operative Nausea and VomitingCompletedNCT03297021Phase 4Results posted
- Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients?TerminatedNCT03262038Phase 4Results posted
- Effects of Ondansetron in Obsessive-compulsive and Tic DisordersCompletedNCT03239210Phase 4Results posted
- PK/PD Study of Netupitant and Palonosetron in Pediatric Patients for Prevention of Chemotherapy-induced Nausea and VomitingCompletedNCT03204279Phase 2Results posted
- Netupitant and Palonosetron Hydrochloride in Preventing Chemotherapy Induced Nausea and Vomiting in Patients With Cancer Undergoing BEAM Conditioning Regimen Before Stem Cell TransplantCompletedNCT03097588Phase 2Results posted
- Netupitant and Palonosetron Hydrochloride in Preventing Chronic Nausea and Vomiting in Patients With CancerCompletedNCT03040726Phase 2/3Results posted
- Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine AdministrationCompletedNCT03035942Phase 4Results posted
- Combination of Netupitant and Palonosetron (Akynzeo®) in the Treatment of Refractory CINVTerminatedNCT03008213Phase 2Results posted
- Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and TemozolomideCompletedNCT02991456Phase 2Results posted
- CSF Pharmacokinetics of OndansetronCompletedNCT02901054Not applicableResults posted
- Effectiveness of Triple Therapy With Palonosetron for PON ProphylaxisCompletedNCT02635828Phase 4Results posted
- Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) ProphylaxisCompletedNCT02625181Not applicableResults posted
- Postoperative Nausea and Vomiting: Ramosetron Plus Aprepitant vs Palonosetron Plus AprepitantCompletedNCT02597907Not applicableResults posted
- An Efficacy and Safety Study of Intravenous Palonosetron Administered as an Infusion and as a Bolus for the Prevention of Nausea and VomitingCompletedNCT02557035Phase 3Results posted
- Efficacy and Safety Study of Fosaprepitant (MK-0517) Plus Ondansetron Versus Ondansetron Alone for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Participants (MK-0517-044)TerminatedNCT02519842Phase 3Results posted
- Granisetron Transdermal Patch for Prevention of Postoperative Nausea and VomitingCompletedNCT02457195Phase 2Results posted
- Scheduled Prophylactic Antiemetics for Reduction of Emesis With Doxycycline (SPARED) TrialCompletedNCT02456662Not applicableResults posted
- Pharmacogenetic Study of Ondansetron in Alcohol Use DisorderCompletedNCT02354703Phase 2Results posted
- Ondansetron for Bipolar Disorder and Alcohol Use DisordersCompletedNCT02082678Phase 4Results posted
- Ondissolve in the Prophylaxis/Rescue of Radiation Induced Nausea and VomitingCompletedNCT02006056Phase 2Results posted
- Sancuso® for Gastroparesis: An Open Label Study.CompletedNCT01989221Phase 3Results posted
- Can Ondansetron Prevent Neonatal Abstinence Syndrome (NAS) in Babies Born to Narcotic-dependent WomenCompletedNCT01965704Phase 2Results posted
- Emergency Department (ED) Drug Interaction in Emergency Department PatientsCompletedNCT01859715Not applicableResults posted
- The Effect of Ondansetron on Cardiac Output in Elective Cesarean DeliveriesCompletedNCT01841606Phase 2Results posted
- How Pregnant Women and Their Babies Metabolize Ondansetron Compared to a Group of Non-pregnant WomenCompletedNCT01801475Phase 1/2Results posted
- Study of the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Fosaprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Children (MK-0517-029)CompletedNCT01697579Phase 2Results posted
- Ondansetron Versus Palonosetron Antiemetic Regimen Prior to Highly Emetogenic Chemotherapy(HEC)CompletedNCT01640340Not applicableResults posted
- 5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical DependenceCompletedNCT01549652Not applicableResults posted
- Oral Ondansetron Versus Transdermal Granisetron (Sancuso) for Women With Cervical, Endometrial or Vaginal Cancer Receiving Pelvic ChemoradiationCompletedNCT01536392Phase 3Results posted
- Reletex Versus Standard of Care Therapy for Post-Operative Nausea Control in Patients Undergoing Foregut SurgeryCompletedNCT01510379Not applicableResults posted
- Aprepitant Versus Ondansetron in Preoperative Triple-therapy Treatment of Nausea and VomitingCompletedNCT01474915Phase 4Results posted
- Efficacy and Safety of Palonosetron Intravenous in Prevention of Chemotherapy Induced Nausea and Vomiting in Pediatric PatientsCompletedNCT01442376Phase 3Results posted
- Safety and Efficacy of Palonosetron IV to Prevent Postoperative Nausea and Vomiting in Pediatric PatientsCompletedNCT01395901Phase 3Results posted
- A Safety Study of Oral Netupitant and Palonosetron for the Prevention of Nausea and VomitingCompletedNCT01376297Phase 3Results posted
- Palonosetron, Ondansetron, and Dexamethasone for Delayed Nausea and Vomiting in Autologous Transplant PatientsCompletedNCT01370408Phase 2Results posted
- An Efficacy and Safety Study of Oral and Intravenous Palonosetron for the Prevention of Nausea and VomitingCompletedNCT01363479Phase 3Results posted
- Ondansetron, Alcohol Use, and Alcohol-Related Symptoms In HIV+ PersonsCompletedNCT01254877Phase 2Results posted
- Three-way Crossover Study Comparing Ondansetron ODFS Administered With and Without Water to Zofran ODT Without WaterCompletedNCT01220167Phase 1Results posted
- Two Way Bioequivalence Study Under Fed ConditionsCompletedNCT01217801Phase 1Results posted
- Crossover Study Comparing Ondansetron Orally Dissolving Film Strip (ODFS) With Zofran Orally Disintegrating TabletsCompletedNCT01217190Phase 1/2Results posted
- Aprepitant and Granisetron for the Prophylaxis of Radiation Induced Nausea and Vomiting - A Pilot StudyTerminatedNCT01183481Phase 2Results posted
- Additional Anti-emetic Effect of Ramosetron Prophylaxis After Total Knee ArthroplastyCompletedNCT01102491Phase 4Results posted
- A Study of Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Participants Who Have Experienced CINV(Chemotherapy-Induced Nausea and Vomiting) During the Previous Cycle of Low Emetogenic Chemotherapy (LEC)CompletedNCT01054456Phase 2Results posted
- Palonosetron Versus Ondansetron for the Prevention of Nausea and VomitingCompletedNCT01031498Phase 2Results posted
- Safety and Efficacy of Aprepitant, Ramosetron, and Dexamethasone for Chemotherapy-Induced Nausea and Vomiting in Patients With Ovarian Cancer Treated With Taxane/CarboplatinCompletedNCT01012336Phase 2Results posted
- Functional Magnetic Resonance Imaging of Opioid Withdrawal in Healthy Human VolunteersCompletedNCT01006707Not applicableResults posted
- Palonosetron for the Treatment of Nausea and Vomiting in Terminally Ill PatientsTerminatedNCT00982995Phase 2Results posted
- Bioequivalence of Two Formulations of Ondansetron in Healthy Adults (0869-106)CompletedNCT00972595Phase 1Results posted