5-HT3 antagonists: all 422 studies that test it
Page 2 of 5. Open to participants first (39), then studies with results posted, then the rest; newest registration first within each.
- Pilot Study to Assess Palonosetron Versus Ondansetron as Rescue Medication in Subjects That Develop Postoperative Nausea and Vomiting (PONV) in the Postanesthesia Care Unit (PACU)CompletedNCT00967499Phase 2Results posted
- Ondansetron Versus Aprepitant Plus Ondansetron for EmesisCompletedNCT00954941Phase 2Results posted
- Efficacy of IV Palo With IV Dexamethasone vs IV Palo for Prevention of Immediate & Delayed PONVCompletedNCT00952133Phase 4Results posted
- Ondansetron HCl Orally Disintegrating Tablets Under Non-Fasting ConditionsCompletedNCT00934921Phase 1Results posted
- Ondansetron HCl Orally Disintegrating Tablets Under Fasting ConditionsCompletedNCT00934180Phase 1Results posted
- Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal CancerTerminatedNCT00903396Phase 2Results posted
- Intravenous Palonosetron With Radiotherapy and Concomitant TemozolomideCompletedNCT00900757Phase 2Results posted
- Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation TherapyTerminatedNCT00895245Phase 2Results posted
- Antiemetic Prophylaxis for Postdischarge Nausea and Vomiting After Hip ArthroscopyCompletedNCT00878228Phase 4Results posted
- Granisetron 1 mg Tablets Under Fasting ConditionsCompletedNCT00834717Phase 1Results posted
- Granisetron 1 mg Tablets, Non-fastingCompletedNCT00834522Phase 1Results posted
- Safety and Efficacy of Palonosetron IV to Prevent Postoperative Nausea and Vomiting in Pediatric PatientsCompletedNCT00828295Phase 3Results posted
- A Study of MK-0869 (Aprepitant) and MK-0517 (Fosaprepitant) in Pediatric Participants Receiving Chemotherapy (MK-0869-134)TerminatedNCT00818259Phase 1Results posted
- Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell TransplantCompletedNCT00795769Phase 2Results posted
- Phase 2 Study of Efficacy, Tolerability, and Safety of Intranasal Granisetron for Chemo-Induced Nausea and VomitingCompletedNCT00787566Phase 2Results posted
- Emend for Multiple-day Emetogenic ChemotherapyCompletedNCT00711555Phase 2Results posted
- New Medication Treatment for Stimulant DependenceCompletedNCT00689572Phase 2Results posted
- Palonosetron and Hydroxyzine to Reduce Opioid WithdrawalCompletedNCT00661674Not applicableResults posted
- Aprepitant for PONV Prophylaxis in Outpatient Plastic SurgeryCompletedNCT00659945Phase 4Results posted
- Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult EDTerminatedNCT00655642Not applicableResults posted
- Aprepitant's Effect on Drug Metabolism in Multi-Day Combination (CHOP/R-CHOP) Chemotherapy Regimen in Lymphoma PatientsCompletedNCT00651755Not applicableResults posted
- Aloxi for Prevention of Chemotherapy Induced Nausea and Vomiting in Malignant Glioma Patients Receiving Irinotecan With BevacizumabTerminatedNCT00636805Phase 2Results posted
- Multi-day Doses in Prevention of Nausea and EmesisCompletedNCT00600353Phase 2Results posted
- Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency DepartmentCompletedNCT00590317Phase 2Results posted
- Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical TrialCompletedNCT00475085Phase 3Results posted
- Effectiveness of Tropisetron Plus Risperidone for Improving Cognitive and Perceptual Disturbances in SchizophreniaCompletedNCT00435370Phase 3Results posted
- Palonosetron for Prevention of Biochemotherapy Induced Nausea and VomitingCompletedNCT00412425Phase 1/2Results posted
- Palonosetron in Sarcoma Patients Receiving Chemotherapy With Adriamycin and Ifosfamide (AI)CompletedNCT00410488Not applicableResults posted
- Phase II Trial of Aprepitant & Palonosetron for CINV Prevention w FOLFOXCompletedNCT00381862Phase 2Results posted
- Study to Assess the Effect Of Alosetron On Mucosal Blood FlowCompletedNCT00370032Phase 4Results posted
- Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast CancerCompletedNCT00343863Not applicableResults posted
- Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell TransplantCompletedNCT00293384Not applicableResults posted
- A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or AdenotonsillectomyCompletedNCT00231478Phase 4Results posted
- Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean SectionCompletedNCT07886151Phase 4
- Prophylactic Ondansetron and Maternal Hemodynamics During Spinal Anesthesia for Elective Cesarean SectionCompletedNCT07883772Not applicable
- Occlusal Splint Combined With Granisetron Injection for Management of Myofascial Pain Related to Temporomandibular DisordersActive, not recruitingNCT07401745Phase 4
- Effect of Ondansetron on Patient Tolerance, Efficacy and Endoscopist Workload in Unsedated Endoscopy for Upper Gastrointestinal BleedingCompletedNCT07336680Phase 4
- Comparison of Intravenous Ondansetron and Low Dose Ketamine in Preventing Post Spinal ShiveringCompletedNCT07334223Not applicable
- Oral Ondansetron to Improve Patient Experience of Unsedated Esophagogastroduodenoscopy Pilot StudyActive, not recruitingNCT07264738Phase 4
- Ondansetron and Dexamethasone for Prevention of PDPH, Nausea, and VomitingCompletedNCT07068230Phase 4
- The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic CholecystectomyCompletedNCT06927817Phase 4
- Efficacy and Safety of Ondansetron Versus Metaclopromide Treatment in Infants With Gastro Oesophageal RefluxCompletedNCT06898268Not applicable
- Ondansetron vs. Dexamethasone for Postoperative NauseaCompletedNCT06886230Phase 4
- A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)Active, not recruitingNCT06780085Phase 2
- Aprepitant and Ondansetron Monotherapy or Combination for Postoperative Nausea and Vomiting in Thyroid CancerCompletedNCT06697782Phase 4
- Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic CholecystectomyActive, not recruitingNCT06632184Phase 4
- A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine SurgeryCompletedNCT06540885Phase 4
- Granisetron Versus Pethidine in Treatment of Post Spinal Shivering in Cesarean SectionsCompletedNCT06513806Phase 4
- Comparative Efficacy of Dexamethasone - Ondansetron Versus Dexamethasone - Haloperidol in Reducing PONVCompletedNCT06428084Phase 2
- NEPA Combined With Olanzapine, Dexamethasone-sparing for the Effect of CINV in Patients Receiving HEC RegimensCompletedNCT06331520Phase 3
- Postoperative Intraperitoneal Pain Management Following Laparoscopic CholecystectomyCompletedNCT06281418Phase 3
- Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Caesarean SectionCompletedNCT06254131Not applicable
- Granisetron Versus Ondansetron for Nausea and Vomiting in Pediatric Age GroupCompletedNCT06175806Not applicable
- The Safety and Efficacy of 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Fecal IncontinenceActive, not recruitingNCT06166615Phase 2/3
- Palonosetron vs Combination of Granisetron and Dexamethasone in Preventing PONV in Laparoscopic Cholecystectomy.CompletedNCT06043336Phase 4
- Palonosetron vs Ondansetron In PONV Prophylaxis Among Idiopathic Scoliosis PatientsCompletedNCT05956899Phase 4
- Postoperative Nausea and Vomiting in Laparoscopic Abdominal SurgeryStatus unknownNCT05632224Phase 4
- Ondansetron and Gabapentin in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve GastrectomyCompletedNCT05620641Phase 3
- Dimenydrinate vs Ondansetron for PONV (DONV)CompletedNCT05590936Not applicable
- Evaluating the Effectiveness of Ondansetron Versus Dexamethasone Versus Placebo for the Control of Intraoperative Nausea and Vomiting in Patients Undergoing Lower-segment Caesarean Section Under Spinal AnesthesiaStatus unknownNCT05583214Phase 4
- Efficacy of Three Antiemetics in Preventing Nausea and VomitingCompletedNCT05533281Phase 4
- Clinical Study of HR20013 for Injection in Patients With Malignant Solid TumorsCompletedNCT05509634Phase 3
- Ondansetron for Postspinal Anesthesia HypotensionCompletedNCT05475873Not applicable
- Study of HR20013 for Injection in Patients With Malignant Solid TumorsCompletedNCT05465681Phase 1
- Effect of Palonosetron, Ondansetron and Dexamethasone in the Prevention of Postoperative Nausea and VomitingStatus unknownNCT05439798Phase 3
- Examining the Effect of Ondansetron on Bowel Prep SuccessCompletedNCT05439772Phase 4
- Safety Study of Repeat Doses of SUSTOL in AdultsActive, not recruitingNCT05434663Phase 4
- The Efficacy of Adjunctive Use of Ondansetron in Patients With Sepsis and Septic ShockStatus unknownNCT05402553Phase 1/2
- Evaluating Neostigmine Effect on Reducing Gastric Residual Volume as Compared With Metoclopramide and OndansetronCompletedNCT05342818Phase 2
- Effect of Glycopyrronium in Combination With Tropisetron in Anti-postoperative Nausea and VomitingCompletedNCT05331651Phase 4
- Ramosetron on Late PONV (Postoperative Nausea and Vomiting)CompletedNCT05326360Phase 4
- Granisetron Transdermal Patch System for Prevention of CINV by CapeOXStatus unknownNCT05325190Phase 2
- Protreat-Trial: Prophylactic Antiemetic Treatment of Opioid-induced Nausea and Vomiting (OINV) in Palliative CareCompletedNCT05315999Phase 2
- Role of Granisetron in Preventing Hypotension After Spinal Anesthesia With Levobupivacaine in Rheumatic Patients Undergoing Elective Cesarean SectionStatus unknownNCT05314257Phase 2/3
- Intrathecal Atropine Versus Intravenous Ondasetron in Post Operative Nausea Due to Intrathecal MorphineStatus unknownNCT05137288Not applicable
- Ephedrine Versus Ondansetron During Cesarean DeliveryCompletedNCT05127876Phase 4
- Effect of Dexmedetomidine on Prevention of Postoperative Nausea and Vomiting in ChildrenCompletedNCT05124067Phase 1
- Effects of Ondansetron, Metoclopramide and Granisetron on Perioperative Nausea and Vomiting in Patients Undergone Bariatric SurgeryCompletedNCT05087615Phase 3
- Ondansetron Versus Domperidone for Treating Vomiting in Acute Gastroenteritis in ChildrenCompletedNCT05076461Not applicable
- Study to Assess Bioequivalence and Adhesion Properties Between Two Granisetron Transdermal Patches.CompletedNCT05027646Phase 1
- Enhanced Recovery Pathway for EndoscopyWithdrawnNCT04983498Phase 4
- A COMPARATIVE STUDY BETWEEN 1MG AND 3 MG OF GRANISETRON IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN STRABISMUS OPHTHALMIC SURGERIES DURING GENERAL ANESTHESIACompletedNCT04918862Phase 3
- Granisetron Transdermal Patch for Prophylaxis of Delayed CINVStatus unknownNCT04912271Phase 3
- Granisteron Versus Metoclopramide in Laparoscopic CholecystectomyStatus unknownNCT04899817Phase 4
- Effect of Ondansetron on Spinal-induced Hypotension for Percutaneous NephrolithotomyCompletedNCT04891484Early Phase 1
- Nefopam Versus Ondansteron for Prevention of Post Spinal Shivering.Status unknownNCT04870541Phase 4
- Hyoscine Butyl-bromide Versus Ondansetron for Nausea and Vomiting During Cesarean Section Under Spinal AnesthesiaCompletedNCT04785118Phase 4
- Interaction Between Tramadol and OndansetronCompletedNCT04745273Phase 4
- ONDANSETRON AND EFFECTIVE DOSE IN 50% OF SUBJECTS OF PROPHYLACTIC NOREPINEPHRINE INFUSIONS FOR PREVENTING SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING CESAREAN DELIVERYStatus unknownNCT04703088Phase 3
- Prevention of Post-Operative ShiveringCompletedNCT04682743Early Phase 1
- Does Higher OT Temperature and IV Ondansetron Reduce Incidence of PSS in Parturients?Status unknownNCT04654429Phase 4
- The Effect of Intravenous Granisetron and Ondansetron in Patients Undergoing Cesarean SectionCompletedNCT04613726Phase 3
- Evaluate Bioequivalence of Palonosetron (0.25mg/5mL)CompletedNCT04585412Phase 4
- Palonosetron Versus Ondansetron for PONV Prevention in Patients Undergoing ERCPStatus unknownNCT04576390Phase 4
- Granisetron vs Granisetron and Dexamethasone on the Reduction of Postoperative Nausea and VomitingStatus unknownNCT04570592Phase 2
- Effect of Palonosetron on Remifentanil for Preventing Emergence Cough in FemaleCompletedNCT04563260Not applicable
- Fosaprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting in Pediatric PatientsCompletedNCT04508400Phase 2
- Open Label Transdermal Granisetron to Relieve Chronic Nausea and EmesisWithdrawnNCT04501211Phase 2
- Ondansetron Effect on Pain Relief After Laparoscopic CholecystectomyCompletedNCT04468685Phase 2
- Efficacy and Safety of the Administration of Ondansetron Versus Habitual Clinical Practice for the Treatment of Vomiting in Children With Mild and Moderate Dehydration: Randomized Clinical TrialStatus unknownNCT04318847Phase 4