Protein Kinase Inhibitors: all 15,278 studies that test it

Page 55 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.

• A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Differentiated Thyroid Cancer (DTC)CompletedNCT01321554Phase 3Results posted
• Study of the Anti-Angiogenesis Agent Axitinib in Patients With Stage III Malignant MelanomaCompletedNCT01321437Phase 2Results posted
• A Phase II Study of Single Agent MEK162 in Patients With Advanced MelanomaCompletedNCT01320085Phase 2Results posted
• MK2206 in Treating Patients With Stage I, Stage II, or Stage III Breast CancerTerminatedNCT01319539Phase 2Results posted
• Research Study of ATG and Rituximab in Renal TransplantationTerminatedNCT01318915Early Phase 1Results posted
• Study of the JAK Inhibitor Ruxolitinib Administered Orally to Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera-Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia-Myelofibrosis (PET-MF)CompletedNCT01317875Phase 1Results posted
• RAD001 With Paclitaxel and Carboplatin in First Line Treatment of Patients With Advanced Large Cell Lung Cancer With Neuroendocrine DifferentiationCompletedNCT01317615Phase 4Results posted
• Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis PemphigusTerminatedNCT01313923Early Phase 1Results posted
• A Study to Evaluate Pazopanib in Comparison to Pemetrexed in Maintenance Setting in Non-progressing Subjects With Metastatic Stage IVA and IVB Non-squamous Non-small Cell Lung Cancer (NSCLC) PopulationTerminatedNCT01313663Phase 2Results posted
• Pasireotide (SOM230) With or Without Everolimus in Treating Patients With Hormone Resistant, Chemotherapy Naive Prostate CancerTerminatedNCT01313559Phase 2Results posted
• Evaluation of the Use of AZD6244 to Induce Increased ER Expression and Anti-Estrogen Response in ER-Negative/Low Breast CancerCompletedNCT01313039Early Phase 1Results posted
• Cediranib Maleate With or Without Gefitinib in Treating Patients With Recurrent or Progressive GlioblastomaTerminatedNCT01310855Phase 2Results posted
• A Study of Tarceva (Erlotinib) as First Line Therapy in Participants With Non-Small Cell Lung Cancer Harbouring Epidermal Growth Factor Receptor (EGFR) MutationsCompletedNCT01310036Phase 2Results posted
• Imatinib and Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host DiseaseCompletedNCT01309997Phase 2Results posted
• A One-Year Study To Evaluate The Efficacy And Safety Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01309737Phase 3Results posted
• Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial CancerCompletedNCT01307631Phase 2Results posted
• A Study of Vemurafenib in Participants With Metastatic MelanomaCompletedNCT01307397Phase 3Results posted
• Dasatinib In Combination With Trastuzumab And Paclitaxel In First Line Treatment Of Her2-Positive MBC PatientsCompletedNCT01306942Phase 1/2Results posted
• Safety and Efficacy Study of Idelalisib (GS-1101, CAL-101) in Patients With Previously Treated Low-grade LymphomaCompletedNCT01306643Phase 1/2Results posted
• Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic MalignanciesCompletedNCT01306045Phase 2Results posted
• A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain MetastasesCompletedNCT01305941Phase 2Results posted
• Allo Transplant Followed by Lenalidomide and Sirolimus Maintenance in High-Risk Multiple Myeloma (MM)TerminatedNCT01303965Phase 1/2Results posted
• Romidepsin and Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Non-Small Cell Lung CancerCompletedNCT01302808Phase 1Results posted
• Study Of Oral PHA-848125AC In Patients With Malignant Thymoma Previously Treated With Multiple Lines Of ChemotherapyTerminatedNCT01301391Phase 2Results posted
• Disposition of 14C-LY3009104 Following Oral Administration in Healthy Human SubjectsCompletedNCT01299285Phase 1Results posted
• Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal CancerCompletedNCT01298570Phase 2Results posted
• Influence of Mild and Moderate Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of Various Doses of AfatinibCompletedNCT01298063Phase 1Results posted
• Relative Bioavailability Of A Crizotinib Oral Liquid Formulation To Crizotinib Formulated CapsuleCompletedNCT01297595Phase 1Results posted
• Safety and Efficacy of BKM120 in Patients With Metastatic Non-small Cell Lung CancerCompletedNCT01297491Phase 2Results posted
• A Biomarker Study of Tivozanib in Subjects With Advanced Renal Cell CarcinomaCompletedNCT01297244Phase 2Results posted
• C14 Study in Oncology Patients With Advanced and/or Metastatic Solid TumorsCompletedNCT01296568Phase 1Results posted
• A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast CancerTerminatedNCT01296555Phase 1Results posted
• MK2206 and Erlotinib Hydrochloride in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Progressed After Previous Response to Erlotinib Hydrochloride TherapyCompletedNCT01294306Phase 2Results posted
• Safety and Tolerability Study of PCI-32765 Combined With Fludarabine/Cyclophosphamide/Rituximab (FCR) and Bendamustine/Rituximab (BR) in Chronic Lymphocytic Leukemia (CLL)CompletedNCT01292135Phase 1Results posted
• Cyclin Dependent Kinase (CDK)4/6 Inhibitor, PD0332991 in Advanced Non-small Cell Lung Cancer NSCLC.CompletedNCT01291017Phase 2Results posted
• Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)CompletedNCT01289912Phase 2Results posted
• First Line Treatment of Metastatic Colorectal Cancer With mFOLFOX6 in Combination With RegorafenibCompletedNCT01289821Phase 2Results posted
• BKM120 as Second-line Therapy for Advanced Endometrial CancerCompletedNCT01289041Phase 2Results posted
• Efficacy of Nilotinib in Adult Patients With Gastrointestinal Stromal Tumors Resistant to Imatinib and Sunitinib.CompletedNCT01289028Phase 3Results posted
• A Study of Tarceva (Erlotinib) in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Who Present EGFR MutationsCompletedNCT01287754Phase 4Results posted
• A Study of LY2090314 in Patients With Advanced or Metastatic CancerCompletedNCT01287520Phase 1Results posted
• A Study of Vemurafenib (RO5185426) in Participants With Metastatic or Unresectable Papillary Thyroid Cancer Positive for the BRAF V600 MutationCompletedNCT01286753Phase 2Results posted
• A Study of AT-101 in Combination With Docetaxel in Squamous Cell Carcinoma Of The Head and NeckTerminatedNCT01285635Phase 2Results posted
• A Dose Escalation/Expansion Study of LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma KinaseCompletedNCT01283516Phase 1Results posted
• A Study of Carboplatin, Cetuximab and RAD001 in Advanced Head and Neck CancerCompletedNCT01283334Phase 1/2Results posted
• A Phase II Study of Akt Inhibitor MK2206 in the Treatment of Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal CancerCompletedNCT01283035Phase 2Results posted
• Efficacy and Safety Study of Idelalisib in Participants With Indolent B-Cell Non-Hodgkin LymphomasCompletedNCT01282424Phase 2Results posted
• Study of Velcade and Temsirolimus for Relapsed or Refractory Non-Hodgkin LymphomaCompletedNCT01281917Phase 2Results posted
• Everolimus in Combination With Imatinib Mesylate in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Soft Tissue SarcomaCompletedNCT01281865Phase 1/2Results posted
• Pazopanib as Single Agent in Advanced NETsCompletedNCT01280201Phase 2Results posted
• Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell LymphomaTerminatedNCT01278615Phase 2Results posted
• Akt Inhibitor MK2206 in Treating Patients With Advanced Breast CancerCompletedNCT01277757Phase 2Results posted
• A Study to Evaluate the Effect of a Proton-Pump Inhibitor (Rabeprazole) on the Relative Bioavailability of Cobimetinib in Healthy ParticipantsCompletedNCT01277718Phase 1Results posted
• A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01276639Phase 3Results posted
• Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform NeurofibromasCompletedNCT01275586Early Phase 1Results posted
• Everolimus in Combination With Imatinib in Patients With Glivec Refractory/Resistant Gastrointestinal Stromal TumorsCompletedNCT01275222Phase 1/2Results posted
• Safety and Efficacy of Nilotinib vs. Imatinib in the Treatment of Newly Diagnosed Chinese Ph+ CML-CP PatientsCompletedNCT01275196Phase 3Results posted
• Study of Nilotinib as First Line Treatment in Philadelphia Chromosome Positive(Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)CompletedNCT01274351Phase 2Results posted
• Tolerability of the Combination of Lapatinib and Trastuzumab in Adults Age 60 or Older With HER2 Positive Locally Advanced or Metastatic Breast CancerActive, not recruitingNCT01273610Phase 2Results posted
• A Study of Lapatinib in Combination With Everolimus in Patients With Advanced, Triple Negative Breast CancerTerminatedNCT01272141Phase 2Results posted
• A Study of Vemurafenib and GDC-0973 (Cobimetinib) in Participants With BRAFV600E Mutation-Positive Metastatic MelanomaCompletedNCT01271803Phase 1Results posted
• LUX-Breast 2; Afatinib in HER2 (Human Epidermal Growth Factor Receptor)-Treatment FailuresCompletedNCT01271725Phase 2Results posted
• Study of Regorafenib as a 3rd-line or Beyond Treatment for Gastrointestinal Stromal Tumors (GIST)CompletedNCT01271712Phase 3Results posted
• E7050 in Combination With Sorafenib Versus Sorafenib Alone as First Line Therapy in Participants With Hepatocellular CarcinomaCompletedNCT01271504Phase 1/2Results posted
• Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid CancerCompletedNCT01270321Phase 2Results posted
• A 12-Day Randomized, Blinded, Vehicle and Active Comparator-Controlled Study to Determine the Efficacy and Safety of Six Concentrations of Topical E6201 Gel in Subjects With Psoriasis VulgarisCompletedNCT01268527Phase 2Results posted
• A Study of E7080 in Subjects With Solid TumorCompletedNCT01268293Phase 1Results posted
• Saracatinib in Treating Patients With Prostate CancerTerminatedNCT01267266Phase 2Results posted
• Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical CancerCompletedNCT01267253Phase 2Results posted
• A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the BrainCompletedNCT01266967Phase 2Results posted
• SCHEDULE - Scandinavian Heart Transplant Everolimus de Novo Study With Early Calcineurin Inhibitor (CNI) AvoidanceCompletedNCT01266148Phase 4Results posted
• TKI 258 in Von Hippel-Lindau Syndrome (VHL)TerminatedNCT01266070Phase 2Results posted
• Chemoprevention of Prostate Cancer, HDAC Inhibition and DNA MethylationCompletedNCT01265953Not applicableResults posted
• A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type FibromatosisCompletedNCT01265030Phase 1/2Results posted
• Study of Bavituximab and Sorafenib In Patients With Advanced Liver CancerCompletedNCT01264705Phase 1/2Results posted
• A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic MelanomaCompletedNCT01264380Phase 1Results posted
• Lapatinib in Stage IV Melanoma With ERBB4 MutationsTerminatedNCT01264081Phase 2Results posted
• Neoadjuvant Axitinib in Locally Advanced Renal Cell Carcinoma (RCC)CompletedNCT01263769Phase 2Results posted
• Pazopanib In Stage IIIB/IV NSCLC Lung Cancer After Progression on First Line Therapy Containing BevacizumabCompletedNCT01262820Phase 2Results posted
• Effects Of CP-690,550 (Tasocitinib) On Cholesterol Metabolism In Patients With Active Rheumatoid ArthritisCompletedNCT01262118Phase 1Results posted
• TKI258 for Metastatic Inflammatory Breast Cancer PatientsCompletedNCT01262027Phase 2Results posted
• Akt Inhibitor MK2206 in Treating Patients With Advanced Gastric or Gastroesophageal Junction CancerCompletedNCT01260701Phase 2Results posted
• Cediranib Maleate With or Without Dasatinib in Patients With HRPC-Resistant to Treatment With DocetaxelCompletedNCT01260688Phase 2Results posted
• A Study of Erlotinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor MutationsCompletedNCT01260181Phase 2Results posted
• A Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or ProgressionCompletedNCT01259869Phase 2Results posted
• Hsp90 Inhibitor AUY922 and Erlotinib Hydrochloride in Treating Patients With Stage IIIB-IV Non-Small Cell Lung CancerCompletedNCT01259089Phase 1/2Results posted
• RAD001 and Intravesical Gemcitabine in BCG-Refractory Primary or Secondary Carcinoma In Situ of the BladderCompletedNCT01259063Phase 1/2Results posted
• Study of Akt Inhibitor MK2206 in Patients With Relapsed LymphomaCompletedNCT01258998Phase 2Results posted
• A Phase 1b Trial in Patients With Renal Cell CancerCompletedNCT01258348Phase 1Results posted
• Treatment of Corneal Neovascularization With Topical PazopanibCompletedNCT01257750Phase 1/2Results posted
• Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT01256398Phase 2Results posted
• Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous TherapyCompletedNCT01256385Phase 2Results posted
• Docetaxel With or Without AZD6244 in MelanomaCompletedNCT01256359Phase 2Results posted
• Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-Pathway in Metastatic, Recurrent or Primary Unresectable Adrenocortical CancerCompletedNCT01255137Phase 2Results posted
• Sorafenib and 5-Azacitidine in Acute Leukemia + Myelodysplastic SyndromeCompletedNCT01254890Phase 1/2Results posted
• Maximal Androgen Depletion Followed by Randomization of Maximal Androgen Ablation With Molecular Targeted TherapiesCompletedNCT01254864Phase 2Results posted
• Safety and Efficacy of Nilotinib in Newly Diagnosed Chronic Myeloid Leukemia PatientsCompletedNCT01254188Phase 3Results posted
• Brivanib Metastatic Renal Cell CarcinomaTerminatedNCT01253668Phase 2Results posted
• A Study of RO5185426 in Previously Treated Melanoma Patients With Brain MetastasesCompletedNCT01253564Phase 2Results posted
• AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT01253447Phase 2Results posted

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