Protein Kinase Inhibitors: all 15,278 studies that test it

Page 56 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.

• Pazopanib in Patients With Relapsed or Refractory Small Cell Lung CancerCompletedNCT01253369Phase 2Results posted
• Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid LeukemiaCompletedNCT01253070Phase 2Results posted
• RAD001 (Everolimus) and Pasireotide (SOM230) LAR in Patients With Advanced Uveal MelanomaCompletedNCT01252251Phase 2Results posted
• Phase l/II Study of Ruxolitinib for Acute LeukemiaTerminatedNCT01251965Phase 1/2Results posted
• Bicalutamide With or Without Akt Inhibitor MK2206 in Treating Patients With Previously Treated Prostate CancerCompletedNCT01251861Phase 2Results posted
• Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell TransplantCompletedNCT01251575Phase 2Results posted
• A Study In Japanese Healthy Male Volunteers To Investigate The Safety, Tolerability And Pharmacokinetics Of PF-02341066CompletedNCT01250730Phase 1Results posted
• A Study to Assess the Incidence of EGFR Mutation in Patients With Newly Diagnosed Locally Advanced or Metastatic Non-Small Cell Lung Cancer in the UK, And of Tarceva (Erlotinib) as First-Line Therapy in EGFR Mutation Positive Patients.CompletedNCT01250119Phase 2Results posted
• A Study of Relative Bioavailability and Food Effect Study of Cobimetinib in Healthy ParticipantsCompletedNCT01249131Phase 1Results posted
• An Absolute Bioavailability Study in Healthy Participants Comparing Oral to Intravenous Administration of GDC-0973 (Cobimetinib)CompletedNCT01249118Phase 1Results posted
• A Study of RO5185426 in Patients With Metastatic MelanomaCompletedNCT01248936Phase 2Results posted
• BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung CancerCompletedNCT01248247Phase 2Results posted
• Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205TerminatedNCT01247922Phase 2Results posted
• Pazopanib Hydrochloride in Treating Patients With Recurrent or Persistent Uterine CancerCompletedNCT01247571Phase 2Results posted
• A Study of LY3009104(Baricitinib) for Healthy SubjectsCompletedNCT01247350Phase 1Results posted
• A Study of LY2157299 in Participants With Hepatocellular CarcinomaCompletedNCT01246986Phase 2Results posted
• CP-690-550 Ointment For Chronic Plaque PsoriasisCompletedNCT01246583Phase 2Results posted
• GSK1120212 vs Chemotherapy in Advanced or Metastatic BRAF V600E/K Mutation-positive MelanomaCompletedNCT01245062Phase 3Results posted
• Tivantinib Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous, Non-small-cell Lung CancerTerminatedNCT01244191Phase 3Results posted
• Study of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea: JAK Inhibitor INC424 (INCB018424) Tablets Versus Best Available Care: (The RESPONSE Trial)CompletedNCT01243944Phase 3Results posted
• A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)TerminatedNCT01243762Phase 1Results posted
• Evaluation of Long-term Safety and Effectiveness of Fostamatinib in the Treatment of Rheumatoid Arthritis (RA)TerminatedNCT01242514Phase 3Results posted
• A Phase 3, Multi Site, Randomized, Double Blind, Placebo Controlled Study Of The Efficacy And Safety Comparing CP- 690,550 And Etanercept In Subjects With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01241591Phase 3Results posted
• A Study of LY2584702 in Solid TumorsCompletedNCT01241461Phase 1Results posted
• Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal TransplantCompletedNCT01239472Phase 4Results posted
• MK2206 in Treating Patients With Advanced Liver Cancer That Did Not Respond to Previous TherapyTerminatedNCT01239355Phase 2Results posted
• Akt Inhibitor MK2206 or Everolimus in Treating Patients With Refractory Kidney CancerTerminatedNCT01239342Phase 2Results posted
• Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01238211Phase 2Results posted
• Intensity-Modulated Radiation Therapy and Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Anaplastic Thyroid CancerCompletedNCT01236547Phase 2Results posted
• Safety and Efficacy of PCI-32765 in Participants With Relapsed/Refractory Mantle Cell Lymphoma (MCL)CompletedNCT01236391Phase 2Results posted
• Study To Evaluate Pharmacokinetics Of Sirolimus In Stable Renal Transplant RecipientsCompletedNCT01236378Phase 1Results posted
• Multiple Ascending Dose of BMS-911543TerminatedNCT01236352Phase 1/2Results posted
• A Study to Evaluate Pazopanib as an Adjuvant Treatment for Localized Renal Cell Carcinoma (RCC)CompletedNCT01235962Phase 3Results posted
• MK-2206, Paclitaxel and Trastuzumab in Treating Patients With HER2-overexpressing Solid Tumor MalignanciesCompletedNCT01235897Phase 1Results posted
• Phase III Trial Comparing Capecitabine in Combination With Sorafenib or Placebo in the Treatment of Locally Advanced or Metastatic HER2-Negative Breast CancerCompletedNCT01234337Phase 3Results posted
• Bosutinib For Autosomal Dominant Polycystic Kidney DiseaseCompletedNCT01233869Phase 2Results posted
• AMG 102 and Erlotinib for Advanced Non-Small Cell Lung CancerCompletedNCT01233687Phase 1/2Results posted
• A Study of Dovitinib Versus Sorafenib in Adult Patients With Hepatocellular Carcinoma (HCC) as a First Line TreatmentCompletedNCT01232296Phase 2Results posted
• Safety and Efficacy of RAD001 (Everolimus) in Combination With Letrozole in the Treatment of Postmenopausal Women With Locally Advanced or Metastatic Breast CancerCompletedNCT01231659Phase 2Results posted
• Study of GSK1120212 Plus Gemcitabine vs Placebo Plus Gemcitabine in Metastatic Pancreatic CancerCompletedNCT01231581Phase 2Results posted
• Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell TransplantCompletedNCT01231412Phase 3Results posted
• Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal CancerCompletedNCT01231399Phase 1/2Results posted
• A Study of Tarceva (Erlotinib) in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Following 4 Cycles of Platinum-based Chemotherapy Without Disease ProgressionCompletedNCT01230710Phase 4Results posted
• Everolimus and Octreotide Acetate With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumors That Cannot Be Removed by SurgeryCompletedNCT01229943Phase 2Results posted
• Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva...CompletedNCT01229150Phase 2Results posted
• Cediranib Maleate and Combination Chemotherapy in Treating Patients With Advanced Biliary CancersTerminatedNCT01229111Phase 2Results posted
• Efficacy and Safety of Pazopanib Monotherapy After First-line Chemotherapy in Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Asian WomenCompletedNCT01227928Phase 2Results posted
• A Study Comparing GSK2118436 to Dacarbazine (DTIC) in Previously Untreated Subjects With BRAF Mutation Positive Advanced (Stage III) or Metastatic (Stage IV) MelanomaCompletedNCT01227889Phase 3Results posted
• CMR Rate of Newly Diagnosed CML-CP Patients Treated With NilotinibCompletedNCT01227577Phase 4Results posted
• A Study of PD 0332991 in Patients With Recurrent Rb Positive GlioblastomaTerminatedNCT01227434Phase 2Results posted
• Nintedanib in Treating Patients With Recurrent or Persistent Endometrial CancerCompletedNCT01225887Phase 2Results posted
• Study of BMS-754807 Combined With Letrozole or BMS-754807 Alone in Patients With Hormone Receptor-Positive Breast Cancer and Resistance to Non-Steroidal Aromatase InhibitorsTerminatedNCT01225172Phase 2Results posted
• Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell CarcinomaCompletedNCT01223027Phase 3Results posted
• Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory RhabdomyosarcomaCompletedNCT01222715Phase 2Results posted
• Selumetinib and Erlotinib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Pancreatic CancerCompletedNCT01222689Phase 2Results posted
• Study of Everolimus (RAD001) in Combination With LenalidomideCompletedNCT01218555Phase 1Results posted
• Dasatinib Combination Therapy With the Smoothened (SMO) Inhibitor BMS-833923 in Chronic Myeloid Leukemia (CML)CompletedNCT01218477Phase 1/2Results posted
• Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-centre, Dose Ranging Study to Evaluate the Efficacy and Safety of Losmapimod Tablets Administered Twice Daily Compared With Placebo for 24 Weeks in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD).CompletedNCT01218126Phase 2Results posted
• Efficacy and Safety Study of PCI-32765 Combine With Ofatumumab in CLLCompletedNCT01217749Phase 1/2Results posted
• Safety and Efficacy Study of PLX3397 in Adults With Relapsed or Refractory Hodgkin LymphomaCompletedNCT01217229Phase 2Results posted
• A Pharmacokinetic and Randomized Trial of Neoadjuvant Treatment With Anastrozole Plus AZD0530 in Postmenopausal Patients With Hormone Receptor Positive Breast CancerCompletedNCT01216176Phase 1/2Results posted
• BIBW 2992 (Afatinib) and Vinorelbine in Japanese Patients With Advanced Solid TumoursCompletedNCT01214616Phase 1Results posted
• A Study in Participants With Acute LeukemiaCompletedNCT01214603Phase 2Results posted
• Ridaforolimus With Cetuximab: Adv Non-Small Cell Lung, Colorectal, Head & Neck CancerTerminatedNCT01212627Phase 1Results posted
• Axitinib For The Treatment Of Advanced Hepatocellular CarcinomaCompletedNCT01210495Phase 2Results posted
• PD0332991 (Palbociclib) in Patients With Advanced or Metastatic LiposarcomaCompletedNCT01209598Phase 2Results posted
• Cediranib Maleate With or Without Lenalidomide for the Treatment of Thyroid CancerCompletedNCT01208051Phase 1/2Results posted
• Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell TumorCompletedNCT01207492Phase 2Results posted
• Ponatinib for Chronic Myeloid Leukemia (CML) Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL)CompletedNCT01207440Phase 2Results posted
• An Open Label Phase I Dose Escalation Trial of Intravenous BI 6727 (Volasertib)in Combination With Oral BIBW 2992 (Afatinib) in Patients With Advanced Solid TumoursCompletedNCT01206816Phase 1Results posted
• A Trial of Everolimis in Patients With Advanced Renal Cell Carcinoma.CompletedNCT01206764Phase 4Results posted
• Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By SurgeryCompletedNCT01206140Phase 2Results posted
• Endocrine Therapy + OSI-906 With or Without Erlotinib for Hormone-Sensitive Metastatic Breast CancerTerminatedNCT01205685Phase 2Results posted
• VEG113971: An Open-Label Study of the Effects of Ketoconazole or Esomeprazole on Pazopanib PKCompletedNCT01205230Phase 4Results posted
• A Study of Erlotinib [Tarceva] as Monotherapy or Intermittent Dosing With Docetaxel in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer. (TALISMAN)CompletedNCT01204697Phase 2Results posted
• A Study of Idelalisib and Rituximab in Elderly Patients With Untreated CLL or SLLTerminatedNCT01203930Phase 2Results posted
• Efficacy, Safety, Tolerability of Gefitinib as 1st Line in Caucasian Patients With EGFR Mutation Positive Advanced NSCLCCompletedNCT01203917Phase 4Results posted
• Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic MalignanciesCompletedNCT01203722Phase 1/2Results posted
• PKC412 and 5-AzacytidineCompletedNCT01202877Phase 1/2Results posted
• Safety and Efficacy of AZD4547 in Combination With Fulvestrant vs. Fulvestrant Alone in ER+ Breast Cancer PatientsCompletedNCT01202591Phase 1/2Results posted
• Erlotinib in Treating Patients With Recurrent or Metastatic Skin Squamous Cell CarcinomaCompletedNCT01198028Phase 2Results posted
• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha AntagonistCompletedNCT01197755Phase 3Results posted
• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding.CompletedNCT01197534Phase 3Results posted
• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Not Responding.CompletedNCT01197521Phase 3Results posted
• Saracatinib and Paclitaxel in Platinum-resistant Ovarian CancerCompletedNCT01196741Phase 2/3Results posted
• Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian CancerCompletedNCT01196429Phase 2Results posted
• A Study of Tarceva (Erlotinib) in Elderly Patients With Advanced Non-Small Cell Lung CancerCompletedNCT01196078Phase 4Results posted
• Rapamycin Therapy in Head and Neck Squamous Cell CarcinomaCompletedNCT01195922Phase 1/2Results posted
• Preoperative Trial of Sorafenib in Combination With Cisplatin Followed by Paclitaxel for Early Stage Breast CancerTerminatedNCT01194869Phase 2Results posted
• Erlotinib Hydrochloride and Radiation Therapy in Stage III-IV Squamous Cell Cancer of the Head and NeckTerminatedNCT01192815Phase 2Results posted
• Erlotinib Re-Challenge for Recurrent EGFR-mutant Lung Cancer in Patients Who Previously Received Adjuvant Erlotinib or GefitinibTerminatedNCT01189435Phase 2Results posted
• Evaluate Safety and Tolerability in Dose Escalation of Sorafenib in Advanced Renal Cell CancerCompletedNCT01189370Phase 2Results posted
• A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis PatientsCompletedNCT01187901Phase 2Results posted
• A Study To Evaluate The Effects And Safety Of Treatment, Treatment Withdrawal, Followed By Re-Treatment With CP-690,550 In Subjects With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01186744Phase 3Results posted
• Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal CancerTerminatedNCT01186705Phase 2Results posted
• Everolimus Versus Sunitinib in Non-Clear Cell Renal Cell CarcinomaTerminatedNCT01185366Phase 2Results posted
• A Study in Participants With Rheumatoid Arthritis on Background Methotrexate TherapyCompletedNCT01185353Phase 2Results posted
• Trial of Induction Chemotherapy With Carboplatin and Paclitaxel, Followed by Concurrent Chemotherapy/Radiation Therapy With ZD1839 (IRESSA), 5-FU, Hydroxyurea, and Twice-Daily Radiation, Followed by Adjuvant ZD1839 Monotherapy in Patients With Locally Advanced Head & Neck CancerCompletedNCT01185171Phase 2Results posted
• Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)CompletedNCT01184898Not applicableResults posted
• A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD ChemotherapyCompletedNCT01184885Early Phase 1Results posted

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