Potassium channel blockers: all 156 studies that test it

Page 1 of 2. Open to participants first (28), then studies with results posted, then the rest; newest registration first within each.

• Randomized Interventional Clinical Trial on the Prevention of Atrial Fibrillation Using Colchicine, Amiodarone And a Posterior Pericardiotomy.Not yet recruitingNCT07887022Phase 3
• Single Dose 4-Aminopyridine for Diagnosing Recurrent Laryngeal Nerve Paralysis Continuity After TraumaNot yet recruitingNCT07832331Phase 1
• The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine UsersRecruitingNCT07532460Not applicable
• Pharmacological Intervention to Prevent NOAF After TAVRNot yet recruitingNCT07519161Not applicable
• Comparative Efficacy of 100-, 200-, & 400-mg Amiodarone in Patients With Paroxysmal AF Depending on Plasma ConcentrationEnrolling by invitationNCT07487714Phase 4
• Evaluation of Two Different Regimens of the Antiarrhythmic Drug Amiodarone to Maintain Normal Sinus Rhythm After Electrical Cardioversion in Patients With Persistent Atrial FibrillationRecruitingNCT07273994Phase 4
• A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 GeneRecruitingNCT07185347Phase 3
• Drug-Drug Interaction of JMKX003142 With Amiodarone and Febuxostat in Healthy SubjectsNot yet recruitingNCT07181265Phase 1
• Preoperative Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal TumorRecruitingNCT07171203Phase 1
• Double Dose 4-AP on Functional Recovery After Spinal Cord InjuryRecruitingNCT06853015Phase 1/2
• Prophylactic Anti-aRrhythmic Therapy With Amiodarone in Critically Ill Patients Admitted for an Out-of-hospital Cardiac Arrest With Initial Shockable RhythmRecruitingNCT06835491Phase 3
• Cross-over Study on the Influence of Fampridine on Working Memory in Mild to Moderate DepressionRecruitingNCT06751784Phase 2
• Efficacy and Safety of Intravenous + Oral Vs. Oral Amiodarone in Preventing Recurrence After Catheter Ablation in Patients with Persistent Atrial FibrillationNot yet recruitingNCT06742866Not applicable
• Early Amiodarone in Shockable Cardiac ArrestRecruitingNCT06680869Phase 3
• Evaluation of Cardioverter Capacity of Amiodarone Pre-electrical Cardioversion in Persistent Atrial FibrillationNot yet recruitingNCT06645249Phase 4
• 4-Aminopyridine to Treat Skin BurnsRecruitingNCT06596434Phase 2
• Role of Eplerenone in Reducing Recurrence of Atrial Fibrillation in Patients With Structural Heart DiseaseRecruitingNCT06556732Phase 1
• 4-aminopyridine for Skin Wound HealingRecruitingNCT06333171Phase 2
• 4AP for Carpal Tunnel Syndrome (CTS)Not yet recruitingNCT06294821Phase 2
• Dalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple SclerosisRecruitingNCT06136728Phase 3
• Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal CancerRecruitingNCT06067438Phase 2
• 4-AP Peripheral Nerve Crossover TrialRecruitingNCT06003166Phase 2
• Pyridostigmine and Amifampridine for Myasthenia GravisRecruitingNCT05919407Phase 3
• Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients Pilot TrialRecruitingNCT05841056Phase 3
• Flecainide Versus Amiodarone in the Cardioversion of Paroxysmal Atrial Fibrillation at the Emergency Department, in Patients With Coronary Artery Disease Without Residual IschemiaRecruitingNCT05549752Phase 3
• Pragmatic Amiodarone Trial to Reduce Postoperative Atrial Fibrillation in Patients Undergoing Cardiac SurgeryNot yet recruitingNCT05543278Phase 4
• Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone TreatmentRecruitingNCT03868150Phase 4
• 4-aminopyridine Treatment for Nerve InjuryRecruitingNCT03701581Phase 2/3
• Repeated Amiodarone Dosing In Cardiac surgicaL ProceduresTerminatedNCT05004077Phase 4Results posted
• A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After TraumaTerminatedNCT04026568Phase 2/3Results posted
• Long Term Safety of Amifampridine Phosphate in Spinal Muscular Atrophy 3TerminatedNCT03819660Phase 2Results posted
• Controlled Trial to Evaluate Amifampridine Phosphate in Spinal Muscular Atrophy Type 3 PatientsCompletedNCT03781479Phase 2Results posted
• Long Term Safety Study of Amifampridine Phosphate in MuSK-MG (Muscle Specific Tyrosine Kinase Myasthenia Gravis)TerminatedNCT03579966Phase 3Results posted
• Study to Evaluate Amifampridine Phosphate in Patients With MuSK-MGCompletedNCT03304054Phase 3Results posted
• Intraoperative Amiodarone to Prevent Atrial Fibrillation in Lung Transplant PatientsCompletedNCT03221764Phase 2Results posted
• CiPA Phase 1 ECG Biomarker Validation StudyCompletedNCT03070470Phase 1Results posted
• Phase 3 Study to Evaluate Efficacy of Amifampridine Phosphate in Lambert-Eaton Myasthenic Syndrome (LEMS)CompletedNCT02970162Phase 3Results posted
• Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic ShockTerminatedNCT02668432Phase 4Results posted
• Effect of Dalfampridine (4-AP) on Genioglossus Muscle Activity in Healthy AdultsCompletedNCT02656160Phase 2Results posted
• Amifampridine Phosphate for the Treatment of Congenital Myasthenic SyndromesCompletedNCT02562066Phase 3Results posted
• Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine.TerminatedNCT02422940Phase 3Results posted
• Study and Treatment of Visual Dysfunction and Motor Fatigue in Multiple SclerosisCompletedNCT02391961Phase 2Results posted
• Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current BlockCompletedNCT02308748Phase 1Results posted
• Efficacy and Safety of 4-aminopyridine on Cognitive Performance and Motor Function of Patients With Multiple SclerosisCompletedNCT02280096Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Two Dose Strengths of Dalfampridine Extended Release Tablets.CompletedNCT02271217Phase 3Results posted
• Efficacy and Safety Study of Prolonged-Release Fampridine in Participants With Multiple SclerosisCompletedNCT02219932Phase 3Results posted
• A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MSCompletedNCT02208050Phase 4Results posted
• Safety and Efficacy of Sustained Release Dalfampridine in Transverse Myelitis (Re-Launch)CompletedNCT02166346Phase 2Results posted
• Effects of Dalfampridine on Cognition in Multiple SclerosisCompletedNCT02006160Phase 2/3Results posted
• Study of the Electrocardiographic Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy SubjectsCompletedNCT01873950Phase 1Results posted
• Dalfampridine and Gait in Spinocerebellar AtaxiasCompletedNCT01811706Not applicableResults posted
• Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord InjuryCompletedNCT01683838Phase 3Results posted
• Short and Long Term Treatment With 4-AP in Ambulatory SMA PatientsCompletedNCT01645787Phase 2/3Results posted
• Pilot Study of Catheter Ablation for Ventricular Tachycardia in Patients With an Implantable Cardioverter DefibrillatorTerminatedNCT01576042Not applicableResults posted
• Combined Amiodarone and Electrical Cardioversion for Postoperative Atrial Fibrillation After Cardiac SurgeryTerminatedNCT01558128Not applicableResults posted
• Effectiveness of 3,4-Diaminopyridine in Lambert-Eaton Myasthenic SyndromeCompletedNCT01511978Phase 2Results posted
• Open-Label Study to Assess the Effect of Long-Term Prolonged-Release Fampridine (BIIB041) on Quality of Life as Reported by Participants With Multiple SclerosisCompletedNCT01480076Phase 4Results posted
• Atrial Fibrillation Without Hemodynamic Instability in the Intensive Care UnitCompletedNCT01461733Phase 4Results posted
• Dalfampridine for Imbalance in Multiple SclerosisCompletedNCT01444300Phase 2Results posted
• Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or TachycardiaCompletedNCT01401647Phase 3Results posted
• A Phase 3 Study of Amifampridine Phosphate in Patients With Lambert Eaton Myasthenic Syndrome (LEMS)CompletedNCT01377922Phase 3Results posted
• A Placebo Controlled Trial of Dalfampridine ER for Ambulatory Activity in People With Multiple SclerosisCompletedNCT01356940Phase 4Results posted
• Catheter Ablation Versus Amiodarone for Shock Prophylaxis in Defibrillator Patients With Ventricular TachycardiaTerminatedNCT01097330Phase 3Results posted
• Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac SurgeryCompletedNCT00953212Phase 3Results posted
• Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple SclerosisCompletedNCT00654927Phase 3Results posted
• Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis Who Participated in the MS-F204 TrialCompletedNCT00649792Phase 3Results posted
• Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR Tablets in Multiple Sclerosis Patients Who Participated in the MS-F203 TrialCompletedNCT00648908Phase 3Results posted
• Amiodarone for the Prevention of Reperfusion Ventricular FibrillationCompletedNCT00587483Not applicableResults posted
• Ablation vs Drug Therapy for Atrial Fibrillation - Pilot TrialCompletedNCT00578617Not applicableResults posted
• Study of Fampridine-SR Tablets in Multiple Sclerosis PatientsCompletedNCT00483652Phase 3Results posted
• Prevention of Atrial Fibrillation Following EsophagectomyCompletedNCT00420017Phase 4Results posted
• A Study of the Effectiveness of Anti-Arrhythmic Medications After Atrial Fibrillation AblationCompletedNCT00408200Not applicableResults posted
• Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung ResectionTerminatedNCT00300495Phase 3Results posted
• Endothelial Hyperpolarization in HumansTerminatedNCT00166166Phase 2Results posted
• Prevention of Atrial Fibrillation Following Noncardiac Thoracic SurgeryCompletedNCT00127712Phase 4Results posted
• Study of Oral Fampridine-SR in Multiple SclerosisCompletedNCT00127530Phase 3Results posted
• Safety and Efficacy Study of Oral Fampridine-SR in Patients With Multiple SclerosisCompletedNCT00053417Phase 2Results posted
• Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord InjuryCompletedNCT00041717Phase 3Results posted
• Effectiveness of Repeated Amiodarone Dosing Regimen Versus Standard Dosing Regimen in Atrial Fibrillation Patient With Rapid Ventricular ResponseCompletedNCT06262932Phase 4
• Effect of Amifampridine on Neuromuscular Transmission in Patients Treated With OnabotulinumtoxinACompletedNCT05769478Phase 1
• Dalfampridine in Egyptian Patients With Multiple SclerosisStatus unknownNCT05730738Not applicable
• Effect of Dalfampridine in Patients With Hereditary Spastic ParaplegiaCompletedNCT05613114Not applicable
• Effects of 4-AP on Functional SCI RecoveryCompletedNCT05447676Early Phase 1
• Refralon Versus Amiodarone for Cardioversion of Paroxysmal Fibrillation and Atrial FlutterCompletedNCT05445297Phase 4
• Influence of Fampridine on Working Memory in Individuals With Post COVID-19 Condition With Subjective Cognitive ImpairmentTerminatedNCT05274477Not applicable
• Catgut Embedding in Acupoints on Treating Persistent Atrial Fibrillation After Catheter AblationStatus unknownNCT05125042Not applicable
• Firdapse for Post-BOTOX Vocal WeaknessCompletedNCT05123053Phase 2
• Prophylactic Amiodarone for Shockable Cardiac ArrestStatus unknownNCT04845607Phase 3
• Influence of Fampridine on Working Memory in Healthy Young SubjectsCompletedNCT04652557Phase 2
• Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation StudyTerminatedNCT04594746Phase 4
• Influence of Fampridine on Working Memory in Healthy SubjectsWithdrawnNCT04516603Phase 2
• Prophylaxis for Patients at Risk to Eliminate Post-operative Atrial FibrillationStatus unknownNCT04392921Not applicable
• Amiodarone or Verapamil in COVID-19 Hospitalized Patients With SymptomsCompletedNCT04351763Phase 2/3
• Prevention of Post-Operative Cardiac ArrhythmiasStatus unknownNCT04234906Phase 4
• Comparison of Two Strategies for the Management of Atrial Fibrillation After Cardiac SurgeryStatus unknownNCT04223739Phase 4
• Fampridine-SR and Optic Neuritis RecoveryStatus unknownNCT04148781Early Phase 1
• Rapid Atrial Fibrillation Treatment StrategyStatus unknownNCT04092621Phase 4
• Prevention of New Onset AF After TAVI (PAF-TAVI Trial)CompletedNCT03991754Phase 3
• Prophylaxis Against Postoperative Atrial Fibrillation in Patients Undergoing On-pump CABGStatus unknownNCT03905759Phase 2/3
• High Doses of 4-aminopyridine in Clinically Complete Chronic Spinal Cord Injury Patients.Status unknownNCT03899584Phase 3

← Potassium channel blockers overview