Phosphodiesterase Inhibitors: all 583 studies that test it

Page 2 of 6. Open to participants first (87), then studies with results posted, then the rest; newest registration first within each.

• Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth RemovedCompletedNCT04132336Phase 2Results posted
• Smell Changes & Efficacy of Nasal TheophyllineCompletedNCT03990766Phase 2Results posted
• Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPDCompletedNCT03984188Phase 3Results posted
• This Study in Healthy Men and Women Tests Whether BI 409306 Has an Effect on the ECG (Thorough QT Study)CompletedNCT03934203Phase 1Results posted
• Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric PatientsCompletedNCT03894904Phase 4Results posted
• Pentoxifylline, Atorvastatin, and Vitamin E in Treating Patients With Erectile Dysfunction After Radiation Therapy for Prostate CancerCompletedNCT03830164Phase 2Results posted
• Ibudilast for the Treatment of Alcohol Use DisorderCompletedNCT03594435Phase 2Results posted
• Caffeine and Neurologic Recovery Following Surgery and General AnesthesiaCompletedNCT03577730Early Phase 1Results posted
• This Study in Healthy Men and Women Tests How the Body Takes up BI 409306CompletedNCT03505151Phase 1Results posted
• Ibudilast and Withdrawal-Related DysphoriaCompletedNCT03489850Phase 2Results posted
• A Study to Determine if Caffeine Accelerates Emergence From Propofol AnesthesiaCompletedNCT03360903Phase 4Results posted
• This Study Tests Whether BI 409306 Prevents Patients With Schizophrenia From Becoming Worse. This Study Looks at How Well Patients Tolerate BI 409306 and How Effective it is Over 6 MonthsTerminatedNCT03351244Phase 2Results posted
• Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) TrialTerminatedNCT03340727Phase 3Results posted
• This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 YearTerminatedNCT03230097Phase 2Results posted
• This Study Tests in Healthy Korean Women Which Effects BI 409306 and a Birth-control Pill Have on Each OtherCompletedNCT03193307Phase 1Results posted
• Drug-drug Interaction Trial Between Rifampicin and BI 409306 in Healthy VolunteersCompletedNCT03151499Phase 1Results posted
• Ibuprofen/Caffeine Lower Back or Neck Pain StudyCompletedNCT03003000Phase 3Results posted
• Exploratory Study to Investigate Cognition Function and Mobility in Individuals With PainTerminatedNCT02974114Phase 4Results posted
• A Dental Pain Study Comparing The Analgesic Efficacy Of Ibuprofen/CaffeineCompletedNCT02863575Phase 3Results posted
• Influence of Fluvoxamine on the Pharmacokinetics of BI 409306CompletedNCT02853136Phase 1Results posted
• Body Composition Changes With Albuterol and Caffeine Versus Placebo in AdolescentsCompletedNCT02740660Not applicableResults posted
• A Biomarker Study to Evaluate MN-166 in Subjects With Amyotrophic Literal Sclerosis (ALS)CompletedNCT02714036Phase 1/2Results posted
• A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the BodyCompletedNCT02688088Phase 1Results posted
• Investigation of Pharmacokinetic Drug-drug Interaction of BI 409306 and Donepezil in Healthy Male and Female SubjectsCompletedNCT02635750Phase 1Results posted
• To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another TabletCompletedNCT02629354Phase 1Results posted
• Trental for the Treatment of Vertigo/Dizziness/ImbalanceTerminatedNCT02592863Not applicableResults posted
• A Study to Determine if Caffeine Accelerates Emergence From AnesthesiaCompletedNCT02567968Phase 4Results posted
• Pentoxifylline Treatment in Acute Pancreatitis (AP)CompletedNCT02487225Phase 3Results posted
• Helping Olfaction and Nutrition On Renal ReplacementCompletedNCT02479451Phase 2Results posted
• Theophylline as a Treatment for Children With Pseudohypoparathyroidism Type 1a (Albright Hereditary Osteodystrophy)CompletedNCT02463409Phase 2Results posted
• Evaluating the Role of Expectations in Response to Caffeine Consumption: An RCTCompletedNCT02461693Not applicableResults posted
• BI 409306 Cardiac Safety Trial in Healthy VolunteersCompletedNCT02438683Phase 1Results posted
• Study of Systemic and Ocular Safety and Pharmacokinetics of BI 409306 in Patients With Schizophrenia, Alzheimer's Disease, and Healthy VolunteersCompletedNCT02392468Phase 1Results posted
• Management of Mandibular ORN: PENTO as Medical TreatmentCompletedNCT02368457Phase 4Results posted
• Enhancement of Corticosteroid Efficacy in COPDCompletedNCT02340520Phase 3Results posted
• BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease.CompletedNCT02337907Phase 2Results posted
• Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord InjuryCompletedNCT02323698Phase 1/2Results posted
• A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks in Patients With Schizophrenia on Stable Antipsychotic Treatment.CompletedNCT02281773Phase 2Results posted
• Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) StudyCompletedNCT02261727Phase 4Results posted
• Drug Drug Interaction Trial With Strong CYP3A4 Inhibitor (Itraconazole) in CYP2C19 Extensive Metabolizers and Poor MetabolizersCompletedNCT02248259Phase 1Results posted
• Alzheimer Disease Proof of Concept Study With BI 409306 Versus PlaceboCompletedNCT02240693Phase 2Results posted
• Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT02238626Phase 2Results posted
• Pharmacokinetics of BI 409306 After a High Fat, High Caloric Meal and After a Single Oral Dose Given at Bed Time in Healthy VolunteersCompletedNCT02222168Phase 1Results posted
• Dipyridamole for Immune Activation in HIVCompletedNCT02121756Phase 1/2Results posted
• Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple SclerosisCompletedNCT01982942Phase 2Results posted
• Study of Human Non-Shivering Thermogenesis and Basal Metabolic RateCompletedNCT01950520Phase 2Results posted
• Efficacy and Safety of Ibuprofen and Caffeine in Dental PainCompletedNCT01929031Phase 3Results posted
• Drug Combination on Exercise Performance at High AltitudeCompletedNCT01902758Phase 2/3Results posted
• Safety and Tolerability of BI 409306 in Patients With SchizophreniaCompletedNCT01892384Phase 1Results posted
• Relative Bioavailability of Ibuprofen From a Single Fixed Dose Combination Tablet of Ibuprofen and Caffeine Compared to Single Tablets of Ibuprofen and Ibuprofen LysinateCompletedNCT01879371Phase 1Results posted
• Effects of Caffeine on Intermittent Hypoxia in Infants Born PretermCompletedNCT01875159Phase 3Results posted
• Trial of Ibudilast for Methamphetamine DependenceCompletedNCT01860807Phase 2Results posted
• Clinical Study to Evaluate Efficacy of New Paracetamol Formulation Compared to Ibuprofen in HeadacheTerminatedNCT01842633Phase 3Results posted
• Safety, Tolerability and Pharmacokinetics of BI 409306 Tablets in Healthy Asian Male VolunteersCompletedNCT01841112Phase 1Results posted
• Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic HepatitisCompletedNCT01809132Phase 2/3Results posted
• Early Versus Routine Caffeine Administration in Extremely Preterm NeonatesCompletedNCT01783561Phase 4Results posted
• Pentoxifylline Therapy in Biliary AtresiaTerminatedNCT01774487Phase 2Results posted
• Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy VolunteersCompletedNCT01766050Phase 4Results posted
• Perioperative Aminophylline to Improve Early Kidney Function After a Kidney TransplantCompletedNCT01759862Not applicableResults posted
• Caffeine to Reduce Mechanical Ventilation in Preterm InfantsTerminatedNCT01751724Not applicableResults posted
• Rapid Acclimatization to Hypoxia at AltitudeCompletedNCT01702025Phase 1/2Results posted
• Effects of Two Doses of a Common Cold Treatment on AlertnessCompletedNCT01686646Phase 3Results posted
• Anti-INFLammatory to Address Mood and Endothelial Dysfunction (INFLAMED)CompletedNCT01625845Phase 2Results posted
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Doses of BI 409306CompletedNCT01611311Phase 1Results posted
• Drug Interaction Study of Colchicine and TheophyllineCompletedNCT01601132Phase 4Results posted
• Safety Evaluation of Aminophylline and MethazolamideCompletedNCT01587027Phase 1Results posted
• The Safety Evaluation of Aminophylline and Ambrisentan When Administered Orally Alone and in Combination to Healthy VolunteersCompletedNCT01530464Phase 1Results posted
• Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected PatientsCompletedNCT01525628Phase 1Results posted
• Evaluation of the Use of Trental and Vitamin E For Prophylaxis of Radiation NecrosisCompletedNCT01508221Phase 2Results posted
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising DosesCompletedNCT01505894Phase 1Results posted
• Assessment of Exposure of BI 409306 in Cerebrospinal Fluid (CSF) Relative to Plasma as Well as to Evaluation of the Effect of Different Doses of BI 409306 on the cGMP (Cyclic Guanosine Monophosphate) Levels in CSF in Healthy Male VolunteersCompletedNCT01493570Phase 1Results posted
• Effects of a Common Cold Treatment on Cognitive FunctionCompletedNCT01466348Phase 4Results posted
• Effect of Pentoxifylline on Proteinuria in Korean Type 2 Diabetic PatientsCompletedNCT01382303Phase 4Results posted
• Safety Tolerability and Pharmacokinetic of BI 409306CompletedNCT01343706Phase 1Results posted
• Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion ImagingCompletedNCT01336140Phase 4Results posted
• Pentoxifylline Treatment of Acute PancreatitisCompletedNCT01292005Early Phase 1Results posted
• A Study of LY2216684 and Theophylline in Healthy SubjectsCompletedNCT01263106Phase 1Results posted
• Study With Aminophylline to Attenuate of the Side Effects of RegadenosonTerminatedNCT01250496Phase 4Results posted
• Pentoxifylline for Primary Biliary CirrhosisCompletedNCT01249092Phase 2Results posted
• Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of MigraineCompletedNCT01248468Phase 4Results posted
• Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac SurgeryCompletedNCT01245595Not applicableResults posted
• A Safety Study of Pentoxifylline for the Treatment of AnemiaTerminatedNCT01102218Phase 2Results posted
• A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic MelanomaCompletedNCT01001299Phase 1Results posted
• Drug-Drug Interaction Study of Colchicine and TheophyllineCompletedNCT00983905Phase 1Results posted
• The Vascular Biology of Dipyridamole in Peripheral Arterial Disease (PAD)TerminatedNCT00906035Not applicableResults posted
• Efficacy of Caffeine Injection as an Adjuvant to Opioid Therapy in Cancer PainCompletedNCT00879775Phase 2Results posted
• Pentoxifylline and Combination Antiretroviral Therapy to Improve Blood Vessel Function in HIV-Infected PeopleCompletedNCT00864916Phase 2Results posted
• MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose CaffeineCompletedNCT00809055Phase 4Results posted
• Evaluating the Effectiveness of Pentoxifylline at Improving Blood Vessel Function in HIV-infected People Not Receiving Antiretroviral MedicationsCompletedNCT00796822Phase 2Results posted
• Drug - Drug Interaction Study Between Quinine Sulfate and TheophyllineCompletedNCT00779259Phase 1Results posted
• The Effects of Pentoxifylline on PAI-1 in an Obese PopulationCompletedNCT00770328Phase 4Results posted
• Persantine: Variation in Response TrialTerminatedNCT00763009Phase 4Results posted
• Open-Label, Multiple-Dose, Non-Randomized Study to Assess Drug-Drug Interactions of Proellex® in Female SubjectsCompletedNCT00741468Phase 1Results posted
• Caffeine and CocaineCompletedNCT00733993Phase 1/2Results posted
• Phase IIa Study of AV411, a Glial Activation Inhibitor, for Opioid WithdrawalCompletedNCT00723177Phase 2Results posted
• Pentoxifylline in Patients With Nonalcoholic SteatohepatitisCompletedNCT00590161Phase 2Results posted
• Trental & Vitamin E for Radiation-Induced FibrosisCompletedNCT00583700Phase 2Results posted
• Clinical Trial of Dipyridamole in SchizophreniaCompletedNCT00349973Not applicableResults posted
• The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).CompletedNCT00273754Phase 2Results posted
• Pentoxifylline/Nonalcoholic Steatohepatitis (NASH) Study: The Effect of Pentoxifylline on NASHCompletedNCT00267670Phase 2/3Results posted

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