Phosphodiesterase Inhibitors: all 583 studies that test it

Page 6 of 6. Open to participants first (87), then studies with results posted, then the rest; newest registration first within each.

• Effects of Caffeine on Women's Sexual ArousalWithdrawnNCT01242046Not applicable
• Study of BCG + Aminophylline Toxicity When Used in the Treatment of Bladder CancerCompletedNCT01240824Early Phase 1
• Safety Interaction Trial Ibudilast and MethamphetamineCompletedNCT01217970Phase 1
• Pharmacokinetic Study to Investigate Low-dose Combinations of a Cocktail of Seven Drugs for Simultaneous Phenotyping of CytochromesCompletedNCT01187862Phase 1
• Efficacy and Safety Study to Compare Ibuprofen + Caffeine With Ibuprofen Alone in the Treatment of HeadacheStatus unknownNCT01172405Phase 3
• Neurophysiological Reserve With Caffeine ManipulationCompletedNCT01167478Not applicable
• Preventive Effect of Enoxaparin, Pentoxifylline and Ursodeoxycholic Acid to Radiation Induced Liver ToxicityCompletedNCT01149304Phase 2
• Renal Effect of Pentoxyphylline in High Risk Patients Undergoing AngiographyWithdrawnNCT01144091Not applicable
• Theophylline in RhinitisCompletedNCT01132781Phase 2
• The Effects of Oral Dipyridamole Treatment on the Innate Immune Response During Human EndotoxemiaCompletedNCT01091571Phase 4
• Prevention of Capsular Contracture Using Trental and Vitamin EStatus unknownNCT01082003Not applicable
• The Effect of Caffeine in Elderly Citizen Following Eight Hour Abstinence From Caffeine Containing Drinks & FoodsCompletedNCT01048515Phase 4
• Caffeine for Apnea of Prematurity-Sleep (CAP-S) StudyCompletedNCT01020357Phase 3
• A Drug-Drug Interaction Study of Abiraterone Acetate Plus Prednisone With Dextromethorphan and Theophylline in Patients With Metastatic Castration-Resistant Prostate CancerCompletedNCT01017939Phase 1
• Role of 'Pentoxifylline and or IgM Enriched Intravenous Immunoglobulin in the Treatment of Neonatal Sepsis'Status unknownNCT01006499Phase 4
• The Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and MoodCompletedNCT00981955Phase 4
• Development of Cocktail for Measuring the Activity of Important Cytochrome P450 EnzymesTerminatedNCT00981929Not applicable
• Chicago Social Drinking ProjectActive, not recruitingNCT00961792Not applicable
• "Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-upStatus unknownNCT00960817Early Phase 1
• AZD2066 Cocktail StudyCompletedNCT00930306Phase 1
• The Effect on Small Airways of Addition of Theophylline as Inducer of Histone Deacilase Activity for Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Treated With Inhaled Steroids and Long Acting Beta AgonistsStatus unknownNCT00893009Not applicable
• Anti-inflammatory Effects of Caffeine in Chronic Obstructive Pulmonary Disease (COPD) SubjectsWithdrawnNCT00826566Not applicable
• Caffeine Versus Placebo for Spinal HeadachesWithdrawnNCT00809627Not applicable
• Determine the Effect of Multiple Doses of AZD7325, CYP StudyCompletedNCT00790114Phase 1
• Persantin Preceding Elective PCICompletedNCT00767663Phase 4
• Effects of Low-Dose Theophylline During Chronic Obstructive Pulmonary Disease (COPD) ExacerbationsCompletedNCT00671151Not applicable
• Assessment of the Effect of Captopril Versus Combination of Captopril and Pentoxifylline on Reducing Proteinuria in Type 2 Diabetic NephropathyCompletedNCT00663949Phase 2/3
• Pentoxifylline and EndometriosisCompletedNCT00632697Phase 3
• Effects of Caffeine in TinnitusCompletedNCT00628316Not applicable
• Treating the Resistant Patent Ductus Arteriosus (PDA)Status unknownNCT00616382Phase 2
• Pilot Study of Pentoxifylline for Hepatopulmonary SyndromeTerminatedNCT00593658Phase 1
• Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of AV411 in Neuropathic PainCompletedNCT00576277Phase 1/2
• The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart DiseaseCompletedNCT00564824Phase 3
• A Possible Therapeutic Role for Adenosine During InflammationCompletedNCT00513110Phase 1
• Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine DependenceStatus unknownNCT00495183Phase 4
• Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent PatientsCompletedNCT00495092Phase 2/3
• Acetylcysteine, Theophylline, and a Combination of Both in the Prophylaxis of Contrast-Induced NephropathyCompletedNCT00492518Phase 4
• Effects of Low Doses of Caffeine on Mood, Physiology and Mental FunctionCompletedNCT00487227Not applicable
• Does a Seven Day Treatment With Dipyridamole Induce Protection Against Ischemia-Reperfusion Injury?CompletedNCT00457405Phase 4
• A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy SubjectsCompletedNCT00443170Phase 1
• Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury?CompletedNCT00430170Phase 4
• "Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous FatCompletedNCT00377975Phase 2
• Efficacy of Pentoxifylline on Primary Nephrotic SyndromeCompletedNCT00354731Phase 3
• Efficacy of Pentoxifylline on Rapidly Progressive GlomerulonephritisTerminatedNCT00354198Phase 3
• A Trial of Pentoxifylline for the Treatment of Recurrent Aphthous StomatitisCompletedNCT00315679Not applicable
• Aminophylline in Bradyasystolic Cardiac ArrestCompletedNCT00312273Phase 2
• Hepatic Drug Biotransformation in Children With Obstructive Sleep ApneaCompletedNCT00310323Not applicable
• B181: Stimulation of Thermogenesis by Bio-Active Food IngredientsCompletedNCT00302289Phase 1
• Theophylline in Chronic Obstructive Pulmonary DiseaseCompletedNCT00299858Phase 2/3
• Pentoxifylline and Progression of Chronic Kidney Disease in Moderate-to-high Risk PatientsCompletedNCT00285298Phase 3
• Pentoxifylline in the Treatment of NEC in Premature NeonatesStatus unknownNCT00271336Phase 2
• Enhancement of Postocclusive Reactive Hyperaemia by DipyridamoleCompletedNCT00268554Not applicable
• Study of Daily Pentoxifylline as a Rescue Treatment in Duchenne Muscular DystrophyCompletedNCT00243789Phase 1/2
• Treatment of Orthostatic Hypotension in Autonomic FailureCompletedNCT00223691Phase 1
• Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans?CompletedNCT00205166Not applicable
• The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast PainTerminatedNCT00188669Phase 2
• The Use of Pentoxifylline and Vitamin E in the Treatment of Late Radiation Related InjuriesTerminatedNCT00188552Phase 2
• The Effect of Caffeine on Ischemic PreconditioningCompletedNCT00184912Not applicable
• Caffeine for Apnea of Prematurity (CAP)CompletedNCT00182312Phase 3
• Differentiation Induction in Acute Myelogenous LeukemiaCompletedNCT00175812Phase 1/2
• Clinical Trial of Pentoxifylline in Patient With CirrhosisCompletedNCT00162552Phase 3
• Metabolic Capacity of Israeli PopulationsStatus unknownNCT00162383Not applicable
• Efficacy of Pentoxifylline on Chronic Kidney DiseaseCompletedNCT00155246Phase 4
• Evaluation of Clinical Efficacy of Pentoxifylline on Patients With GlomerulonephritisCompletedNCT00154661Not applicable
• Pentoxifylline in Children With MalariaTerminatedNCT00133393Phase 2
• Rosiglitazone Versus Theophylline in Asthmatic SmokersCompletedNCT00119496Phase 2/3
• The Effect of Caffeine in Elderly CitizensCompletedNCT00117520Phase 4
• Pentoxifylline in Duchenne Muscular DystrophyCompletedNCT00102453Phase 1/2
• Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate CancerCompletedNCT00080808Phase 2
• Vitamin E and Pentoxifylline in Treating Women With Lymphedema After Radiation Therapy for Breast CancerCompletedNCT00022204Phase 2
• Radiation Therapy in Treating Patients With GlioblastomaCompletedNCT00019058Phase 1
• Theophylline in Treating Patients With In Situ, Stage I, or Stage II Chronic Lymphocytic LeukemiaCompletedNCT00003808Phase 2
• Theophylline in Treating Cancer Patients With Shortness of BreathCompletedNCT00003684Phase 3
• S9700 Combination Chemotherapy in Treating Patients With Stage II or Stage III Pancreatic CancerCompletedNCT00003018Phase 2
• Methotrexate Plus Dipyridamole in Treating Patients With Advanced Ovarian CancerStatus unknownNCT00002487Phase 2
• A Study of Multiple Doses of Vesnarinone in Advanced HIV DiseaseCompletedNCT00002337Phase 1
• A Pilot Study of OPC-8212 (Vesnarinone) in Persons With AIDS-Related Kaposi's SarcomaCompletedNCT00002131Phase 2
• A Long-Term, Follow-On Safety Study of Four Doses of OPC-8212 (Vesnarinone) in HIV-Infected PersonsCompletedNCT00002130Not applicable
• A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3CompletedNCT00002129Phase 1
• An Evaluation of Pentoxifylline in HIV-Positive Persons With Symptomatic HIV Infection and a Karnofsky Score > 40 Percent and < 100 PercentCompletedNCT00002091Not applicable
• Treatment of Pulmonary Sarcoidosis With PentoxifyllineCompletedNCT00001877Phase 2
• Trial of Pentoxifylline in Patients With Functional Disability Caused by Radiation-Induced Advanced Regional FibrosisCompletedNCT00001437Phase 2
• Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDSCompletedNCT00000646Phase 1

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