DrugBiological
Peginterferon alfa-2b clinical trials
Also written PegIntron, PEG-interferon alfa-2b, SCH 054031 and SCH 54031.
- studies test it
- 135
- open now
- 12
- in phase 3
- 41
- first study started
- 1997
Keep track of what changes. Save the peginterferon alfa-2b studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Studies by the year they started
131 studies that test it; most in 2006 (11)
| Year | Studies |
|---|---|
| 1997 | 2 |
| 1998 | 2 |
| 2000 | 5 |
| 2001 | 4 |
| 2002 | 10 |
| 2003 | 4 |
| 2004 | 4 |
| 2005 | 9 |
| 2006 | 11 |
| 2007 | 10 |
| 2008 | 10 |
| 2009 | 3 |
| 2011 | 7 |
| 2012 | 11 |
| 2013 | 9 |
| 2014 | 10 |
| 2015 | 2 |
| 2016 | 1 |
| 2017 | 2 |
| 2019 | 1 |
| 2020 | 3 |
| 2022 | 2 |
| 2023 | 1 |
| 2024 | 5 |
| 2025 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 22
- Phase 2
- 48
- Phase 3
- 41
- Phase 4
- 18
- No phase
- 13
What it is tested for
Each study’s main condition, where its own words name it.
- Melanoma
- 14
Who runs them
Industry 53 · Other 82
Merck Sharp & Dohme LLC (37) · M.D. Anderson Cancer Center (7) · Tanabe Pharma Corporation (5) · National Institute of Allergy and Infectious Diseases (NIAID) (4) · National Cancer Institute (NCI) (4) · Xiamen Amoytop Biotech Co., Ltd. (2) · The Wistar Institute (2) · H. Lee Moffitt Cancer Center and Research Institute (2)
Often tested with
Tested in the same studies.
Ribavirin (41) · Telaprevir (6) · Boceprevir (5) · Peginterferon alfa-2a (3) · Nilotinib (2) · Imatinib (2) · Temozolomide (2) · Pembrolizumab (2)
Studies
Open first, then newest update. How each study uses peginterferon alfa-2b is read from its arms, and is right about nine times in ten.
Testing it · 135
- Efficacy and Safety of Pegylated Interferon Alpha-2β in Patients With Hepatitis B-related Hepatocellular Carcinoma After Radical ResectionNot yet recruitingEarly Phase 1Ningbo No.2 HospitalNCT07553767Written as Peginterferon alfa-2b
- Prospective Cohort Study on PEG-IFN-α-2b in Improving Clinical Cure Rate of Pediatric Patients With Chronic Hepatitis BNot yet recruitingPhase 4Nanfang Hospital, Southern Medical UniversityNCT07231276Written as Peginterferon alfa-2b Injection
- Peginterferon α-2b Injection for Hydroxyurea Resistant or Intolerant ETRecruitingPhase 2Xiamen Amoytop Biotech Co., Ltd.NCT06552429Written as Peginterferon α-2b injection
- Clinical Trial of Pegylated Interferon α-2b Via Nebulization for Treatment of Hand, Foot, and Mouth Disease .RecruitingNot applicableZhengzhou Children's Hospital, ChinaNCT07008755Written as Peginterferon α-2b injection
- Peginterferon Treatment Study for Inactive Chronic Hepatitis B PatientsRecruitingPhase 4Third Affiliated Hospital, Sun Yat-Sen UniversityNCT05182463Written as Peginterferon Alfa-2B
- Peginterferon α-2b Injection for Aerosol Therapy in Pediatric Respiratory Syncytial Virus PneumoniaRecruitingNot applicableWest China Second University HospitalNCT06881056Written as Peginterferon α-2b injection
- Peginterferon α-2b Injection for the Treatment of Pediatric RSV BronchiolitisRecruitingNot applicableChildren's Hospital of Soochow UniversityNCT06827249Written as Peginterferon α-2b injection
- Clinical Study of Antiviral Therapy Combined With Novel Immunotherapy for CHB in AdultsEnrolling by invitationNot applicableBeijing Ditan HospitalNCT06777173Written as Peg interferon alfa-2b
- Efficacy and Safety of Peginterferon in ET and PV.RecruitingNot applicableZhenya HongNCT06734637Written as Peginterferon α-2b injection
- Pegylated Interferon Alfa-2b Versus Interferon Alfa Therapy in Childhood and Adolescent Essential ThrombocythemiaRecruitingPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT04226950Written as Pegylated interferon alfa-2b
- Pegylated Interferon Alfa-2b Versus Interferon Alfa Therapy in Adult Essential ThrombocythemiaRecruitingPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT05395507Written as Pegylated interferon alfa-2b
- Peginterferon α-2b Combined CO2 Laser in Condylomata AcuminataNot yet recruitingNot applicableZhangyu BuNCT06430190Written as Peginterferon α-2b injection
- Intraperitoneal Infusion of Autologous Monocytes With Sylatron (Peginterferon Alfa-2b) and Actimmune (Interferon Gamma-1b) in Women With Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal CancerTerminatedPhase 1National Cancer Institute (NCI)NCT02948426Written as Autologous Monocytes + ACTIMMUNE + SYLATRON
- Efficacy and Safety of MP-424, Peginterferon Alfa-2b and Ribavirin in Chronic Hepatitis C Who Have Not Achieved an Undetectable HCV RNA Level With Previous Interferon Based TherapyCompletedPhase 3Tanabe Pharma CorporationNCT00781274Written as Peginterferon Alfa-2b
- Efficacy and Safety of MP-424, Peginterferon Alfa-2b and Ribavirin in Relapser Genotype 2 Hepatitis C Infected PatientsCompletedPhase 3Tanabe Pharma CorporationNCT01466192Written as Peginterferon alfa-2b
- A Phase 1 Study of MP-424, Peginterferon Alfa 2b, and Ribavirin in Hepatitis CCompletedPhase 1Tanabe Pharma CorporationNCT00630058Written as MP-424(H), PEG-IFN-a-2b, RBV
- Efficacy and Safety of MP-424, Peginterferon Alfa-2b, and Ribavirin in Patients With Chronic Hepatitis C Who Relapsed After Previous Interferon Based TherapyCompletedPhase 3Tanabe Pharma CorporationNCT00780910Written as Peginterferon Alfa-2b
- Efficacy and Safety of MP-424, Peginterferon Alfa-2b and Ribavirin in Non-responder Genotype 2 Hepatitis C Infected PatientsCompletedPhase 3Tanabe Pharma CorporationNCT01468584Written as Peginterferon alfa-2b
- Pegylated Interferon Alfa-2b and Nilotinib for Augmentation of Complete Molecular Response in Chronic Myeloid LeukaemiaCompletedPhase 2Australasian Leukaemia and Lymphoma GroupNCT02001818Written as Nilotinib, Pegylated interferon alpha-2b, Imatinib
- A Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis BCompletedPhase 3Xiamen Amoytop Biotech Co., Ltd.NCT04846491Written as Peginterferon alfa-2b injection
See all 135 studies that test peginterferon alfa-2b →
Given in every arm · 46 — peginterferon alfa-2b is usual care beside what is tested
- Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PVRecruitingPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT05870475Written as Pegylated interferon α-2b
- Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk MelanomaActive, not recruitingPhase 2St. Jude Children's Research HospitalNCT00539591Written as Peginterferon alfa-2b
- Efficacy of Prazosin Versus Placebo Associated With Peg-interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe FibrosisCompletedPhase 2French National Agency for Research on AIDS and Viral HepatitisNCT00148837Written as Peg-interferon alpha 2b + Ribavirin(drug)
- Efficacy of PegInterferon-Ribavirin-Boceprevir Therapy in Patients Infected With G1 HCV With Cirrhosis, Awaiting Liver TransplantationCompletedPhase 2French National Agency for Research on AIDS and Viral HepatitisNCT01463956Written as Peg-Interferon α-2b or Peg-Interferon α-2a
- Efficacy and Safety of MP-424/Peginterferon Alfa-2b/Ribavirin Combination in Treatment-Naïve Patients With Chronic Hepatitis CCompletedPhase 3Tanabe Pharma CorporationNCT00780416Written as Peginterferon Alfa-2b
- HIV Patients With Chronic Hepatitis C Genotype 1 Infection Who Failed Previously to Peginterferon /RibavirinTerminatedPhase 3Anna CrucetaNCT01718301Written as Peginterferon alfa-2b
- Grazoprevir (MK-5172) Administered With Peginterferon and Ribavirin in Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-003)CompletedPhase 2Merck Sharp & Dohme LLCNCT01353911Written as Peg-interferon alfa-2b
- Grazoprevir (MK-5172) With Peg-Interferon and Ribavirin in Participants With Chronic Genotype 2 or 3 Hepatitis C (MK-5172-012)TerminatedPhase 2Merck Sharp & Dohme LLCNCT01440595Written as Peginterferon alfa-2b (Peg-IFN)
- Safety and Tolerability of Pembrolizumab (MK-3475) + Pegylated Interferon Alfa-2b and Pembrolizumab+ Ipilimumab in Participants With Advanced Melanoma or Renal Cell Carcinoma (MK-3475-029/KEYNOTE-29)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT02089685Written as PegIFN-2b
- Peginterferon Alpha-2b Therapy in Chronic Hepatitis Patients With Normal ALT Level and Low ViremiaStatus unknownPhase 1/2Fuzhou General HospitalNCT05203055Written as Peginterferon alpha-2b
- Boceprevir/Peginterferon/Ribavirin for Chronic Hepatitis C: Erythropoietin Use Versus Ribavirin Dose Reduction for Anemia (P06086 AM2)CompletedPhase 3Merck Sharp & Dohme LLCNCT01023035Written as Peginterferon alfa-2b (PEG2b)
- Boceprevir Treatment in Participants With Chronic Hepatitis C Genotype 1 Deemed Nonresponders to Peginterferon/Ribavirin (P05514)CompletedPhase 3Merck Sharp & Dohme LLCNCT00910624Written as Peginterferon alfa-2b (SCH 54031)
- The Effect of Boceprevir in Russian Participants Diagnosed With Chronic Hepatitis C Genotype 1 (P08160)CompletedPhase 3Merck Sharp & Dohme LLCNCT01425203Written as peginterferon alfa-2b
- Peginterferon and TIL Therapy for Metastatic MelanomaCompletedPhase 1/2Inge Marie SvaneNCT02379195Written as Peginterferon alfa-2b
- Optimized Treatment of Peginterferon Alfa 2a/2b in Treatment Experienced Patients With HBV Related Liver FibrosisStatus unknownNot applicableThird Affiliated Hospital, Sun Yat-Sen UniversityNCT03920605Written as Peginterferon Alfa-2b
- Optimized Treatment of Peginterferon Alfa 2a/2b in Anti-virus Treatment Naive Patients With HBV Related Liver FibrosisStatus unknownNot applicableThird Affiliated Hospital, Sun Yat-Sen UniversityNCT03919565Written as Peginterferon Alfa-2b
- Efficacy and Safety of Narlaprevir Used in Combination With Ritonavir in Treatment-Naïve and Failed Prior Treatment With Pegylated Interferon/Ribavirin Patients With Chronic Hepatitis C Genotype 1 (PIONEER - Study)CompletedPhase 3R-PharmNCT03833362Written as Pegylated interferon alfa-2a/ Pegylated interferon alfa-2b
- Parallel Phase I/II Trial of Decitabine and Peg-Interferon in Melanoma: Phase I PortionTerminatedPhase 1M.D. Anderson Cancer CenterNCT00791271Written as Pegylated Interferon Alpha-2b
- Efficacy and Safety of Combination Grazoprevir (MK-5172)/Elbasvir (MK-8742) Versus Sofosbuvir + Pegylated Interferon + Ribavirin in Hepatitis C Virus Genotype 1, 4 or 6 Infection (MK-5172-077)CompletedPhase 3Merck Sharp & Dohme LLCNCT02358044Written as PegIntron
- Safety and Efficacy of Boceprevir in Asia Pacific Participants With Chronic Hepatitis C Genotype 1 (P07063)CompletedPhase 3Merck Sharp & Dohme LLCNCT01390844Written as Peginterferon alfa-2b (PEG)
Showing 20 of 46.
As the comparator · 13 — what is tested is compared with peginterferon alfa-2b
- Pegylated Interferon Alfa-2b in Reducing Relapse Rates After Nucleos(t)ide Analogue Withdrawal in HBeAg-negative CHB Patients with Low Level HBsAgNot yet recruitingPhase 4Huashan HospitalNCT06900166Written as PegIFN alfa-2b
- Ropeginterferon Alfa-2b (P1101) Phase 3 Study in Interferon Treatment-Naive Subjects With HCV Genotype 2 InfectionCompletedPhase 3PharmaEssentiaNCT04382937Written as PEG-Intron + Ribavirin
- Safety and Efficacy Study to Compare Continuous Infusion of Interferon With Standard of Care for Chronic Hepatitis CCompletedPhase 2Medtronic Corporate Technologies and New VenturesNCT00919633Written as peginterferon alfa-2b
- An Open-label Randomized Multicenter Phase III Clinical Study Comparing Safety and Efficacy of Algeron (Cepeginterferon Alfa-2b) and and PegIntron (Peginterferon Alfa-2b) in Combination With Ribavirin as Combined Treatment of Chronic Hepatitis C in Human Immunodeficiency Virus-1 Infected PatientsCompletedPhase 3BiocadNCT02103439Written as PegIntron
- Extended Treatment With PEG-Intron® and Rebetol® in Patients With Genotype 1 Chronic Hepatitis C and Slow Virologic Response (Study P03685)CompletedPhase 3Merck Sharp & Dohme LLCNCT00265395Written as Combination of pegylated interferon alfa-2b (PEG-Intron®) and ribavirin (Rebetol®)
- Peak Study - A Study of Pegasys (Peginterferon Alfa-2a (40KD)) in Combination With Copegus (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C (CHC).CompletedPhase 4Hoffmann-La RocheNCT00087607Written as Peginterferon alfa-2b (PEG-Intron)
- The SIM-SOF Trial for Hepatitis CCompletedPhase 4Center For Hepatitis C, Atlanta, GANCT02168361Written as Pegylated Interferon alfa-2b
- Grazoprevir (MK-5172)/Elbasvir (MK-8742) Versus Boceprevir/Pegylated Interferon/Ribavarin for Chronic Hepatitis C Infection (MK-5172-066)WithdrawnPhase 3Merck Sharp & Dohme LLCNCT02204475Written as PegIntron
- Algeron (Cepeginterferon Alfa-2b) Compared With PegIntron (Peginterferon Alfa-2b) for Treatment of Chronic Hepatitis CCompletedPhase 2/3BiocadNCT01740089Written as PegIntron
- NASVAC Phase-III Trial in Chronic Hepatitis B (CHB) PatientsStatus unknownPhase 3Clinical Research Organization, Dhaka, BangladeshNCT01374308Written as Pegylated interferon alpha 2b
- Does Induction PEG-Intron in Combination With Rebetol Enhance the Sustained Response Rates in Patients With CHCCompletedPhase 4Brooke Army Medical CenterNCT00207363Written as Ribavirin, Peg interferon alfa 2b
- Study of Safety, Tolerability, and Anti-Viral Effect of Locteron Compared to PEG-Intron in Patients With Chronic Hepatitis CCompletedPhase 1/2Biolex Therapeutics, Inc.NCT00593151Written as pegylated IFNa2b
- Phase 2B Dose Ranging Study of Locteron Plus Ribavirin to Treat HCVCompletedPhase 2Biolex Therapeutics, Inc.NCT00863239Written as PEG-Intron™
Codes
What other systems call peginterferon alfa-2b · ClinicalTrials.gg INT004289
- MeSH (NLM) C417083peginterferon alfa-2bConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) G8RGG88B68PEGINTERFERON ALFA-2BConfirmed FDA, NLM, Wikidata
- RxNorm 253453Confirmed FDA, Wikidata
- Wikidata Q7160789peginterferon alfa-2bConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1845Peginterferon Alfa-2bOne source FDA
- DrugBank DB00022One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C417083 | peginterferon alfa-2b | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | G8RGG88B68 | PEGINTERFERON ALFA-2B | Confirmed FDA, NLM, Wikidata |
| RxNorm | 253453 | — | Confirmed FDA, Wikidata |
| Wikidata | Q7160789 | peginterferon alfa-2b | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1845 | Peginterferon Alfa-2b | One source FDA |
| DrugBank | DB00022 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.