Drug
N,N-Dimethyltryptamine clinical trials
Also written DMT and SPL026.
- studies test it
- 18
- open now
- 5
- in phase 3
- 0
- first study started
- 2020
Keep track of what changes. Save the N,N-Dimethyltryptamine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
- DMT
- 12
Combined with it in one product
Studies by the year they started
18 studies that test it; most in 2023 (5)
| Year | Studies |
|---|---|
| 2020 | 2 |
| 2021 | 2 |
| 2022 | 3 |
| 2023 | 5 |
| 2024 | 1 |
| 2025 | 3 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 12
- Phase 2
- 3
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 5 · Other 13
University Hospital, Basel, Switzerland (5) · Small Pharma Ltd (3) · Universidade Federal do Rio Grande do Norte (3) · Algernon Pharmaceuticals (1) · Milan Scheidegger (1) · Biomind Labs Inc. (1) · Psychiatric University Hospital, Zurich (1) · Jon Dean (1)
Often tested with
Tested in the same studies.
Harmine (2) · Ketamine (1) · Dextromethorphan (1) · N-Methyl-3,4-methylenedioxyamphetamine (1) · Dronabinol (1) · Lysergic Acid Diethylamide (1) · Psilocybin (1)
Studies
Open first, then newest update. How each study uses N,N-Dimethyltryptamine is read from its arms, and is right about nine times in ten.
Testing it · 18
- Inhaled DMT for Major Depressive DisorderRecruitingPhase 2Universidade Federal do Rio Grande do NorteNCT07562191Written as N,N-Dimethyltryptamine (15 mg + 60 mg)
- Neural Effects of Intravenous N,N-dimethyltryptamine (DMT)Not yet recruitingPhase 1Jon DeanNCT07693257Written as N,N-Dimethyltryptamine (15 mg)
- Antidepressant Response of DMT Masked With PropofolRecruitingNot applicableUniversity Hospital, Basel, SwitzerlandNCT06927076Written as N,N-Dimethyltryptamine
- Investigation of Psychedelic Effects in Psychoactive SubstancesRecruitingPhase 1Johns Hopkins UniversityNCT06772753Written as Dimethyltryptamine (DMT)
- Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy ParticipantsRecruitingPhase 1University Hospital, Basel, SwitzerlandNCT06899334Written as DMT
- Acute Dose-dependent Effects of DMT-bolus Applications in Healthy Subjects (DMT BDR-Study)CompletedPhase 1University Hospital, Basel, SwitzerlandNCT05695495Written as N,N-Dimethyltryptamine (5mg)
- Single and Repeat Doses of DMT in Healthy SubjectsActive, not recruitingPhase 1Algernon PharmaceuticalsNCT05559931Written as N,N-Dimethyltryptamine
- SPL026 With or Without SSRIs in Participants With MDDCompletedPhase 1Small Pharma LtdNCT05553691Written as SPL026
- Safety, Tolerability and Antidepressant Effects of DMT in Patients With DepressionCompletedPhase 2Universidade Federal do Rio Grande do NorteNCT06094907Written as N,N-Dimethyltryptamine
- Acute Dose-dependent Effects of DMT in Healthy SubjectsCompletedPhase 1University Hospital, Basel, SwitzerlandNCT05384678Written as N,N-Dimethyltryptamine (54 mg)
- SPL026 (DMT Fumarate) in Healthy Subjects and MDD PatientsCompletedPhase 1/2Small Pharma LtdNCT04673383Written as SPL026
- IM and IV SPL026 Drug Product in Healthy ParticipantsCompletedPhase 1Small Pharma LtdNCT05644093Written as SPL026 IV
- Safety and Tolerability of DMT in Healthy AdultsCompletedPhase 1Universidade Federal do Rio Grande do NorteNCT05901012Written as N,N-Dimethyltryptamine
- Mindfulness and PsychedelicsCompletedEarly Phase 1Milan ScheideggerNCT05780216Written as DMT + harmine
- Clinical Study of DMT in Healthy AdultsCompletedPhase 1Biomind Labs Inc.NCT05573568Written as N,N-Dimethyltryptamine
- Effects of Dimethyltryptamine in Healthy SubjectsCompletedPhase 1University Hospital, Basel, SwitzerlandNCT04353024Written as Dimethyltryptamine (DMT)
- Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy SubjectsCompletedEarly Phase 1Psychiatric University Hospital, ZurichNCT04716335Written as DMT
- Discontinuing Disease-modifying Therapies in Stable Relapsing - Onset Multiple Sclerosis (DOT-MS).Status unknownNot applicableAmsterdam UMC, location VUmcNCT04260711Written as DMT
Codes
What other systems call N,N-Dimethyltryptamine · ClinicalTrials.gg INT007371
- MeSH (NLM) D004130N,N-DimethyltryptamineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) WUB601BHAADIMETHYLTRYPTAMINEConfirmed FDA, NLM, Wikidata
- Wikidata Q407217dimethyltryptamineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C206901DimethyltryptamineOne source FDA
- DrugBank DB01488One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004130 | N,N-Dimethyltryptamine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | WUB601BHAA | DIMETHYLTRYPTAMINE | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q407217 | dimethyltryptamine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C206901 | Dimethyltryptamine | One source FDA |
| DrugBank | DB01488 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.