Histone Deacetylase Inhibitors: all 1,242 studies that test it

Page 5 of 13. Open to participants first (144), then studies with results posted, then the rest; newest registration first within each.

• Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00731731Phase 1/2Results posted
• Study of the Safety and Tolerability of PCI-24781 in Patients With LymphomaCompletedNCT00724984Phase 1/2Results posted
• Panobinostat in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myeloid LeukemiaTerminatedNCT00723203Phase 2Results posted
• Vorinostat and Rituximab in Treating Patients With Indolent Non-Hodgkin LymphomaCompletedNCT00720876Phase 2Results posted
• Bortezomib and Vorinostat in Treating Patients With Recurrent Mantle Cell Lymphoma or Recurrent and/or Refractory Diffuse Large B-Cell LymphomaCompletedNCT00703664Phase 2Results posted
• Carboplatin and Etoposide in Combination With Vorinostat for Patients With Extensive Stage Small Cell Lung CancerTerminatedNCT00702962Phase 1/2Results posted
• LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML)CompletedNCT00691938Phase 1/2Results posted
• Study to Evaluate Exemestane With and Without Entinostat (SNDX-275) in Treatment of Postmenopausal Women With Advanced Breast CancerCompletedNCT00676663Phase 2Results posted
• Vorinostat and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid LeukemiaTerminatedNCT00673153Phase 2Results posted
• Valproic Acid in Treating Patients With Progressive, Non-Metastatic Prostate CancerTerminatedNCT00670046Phase 2Results posted
• Efficacy and Safety Study of Panobinostat in Participants With Metastatic Hormone Refractory Prostate CancerCompletedNCT00667862Phase 2Results posted
• Vorinostat, Paclitaxel, and Radiation Therapy in Treating Patients Unable to Tolerate Cisplatin With Stage III Non-Small Lung Cancer That Cannot Be Removed By SurgeryTerminatedNCT00662311Phase 1/2Results posted
• CARNIVAL Type I: Valproic Acid and Carnitine in Infants With Spinal Muscular Atrophy (SMA) Type ICompletedNCT00661453Phase 1/2Results posted
• Phase II Study of Idarubicin, Cytarabine, and Vorinostat With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)CompletedNCT00656617Phase 2Results posted
• Vorinostat (MK-0683, SAHA [Suberoylanilide Hydroxamic Acid]) + Lenalidomide + Dexamethasone in Multiple Myeloma (MM) (MK-0683-074)CompletedNCT00642954Phase 1Results posted
• A Crossover Study to Assess the Effects of Vorinostat (MK0683, SAHA) in Patients With Advanced Cancer (0683-070)(COMPLETED)CompletedNCT00632931Phase 1Results posted
• A Study of Oral LBH589 in Adult Patients With Advanced Hematological MalignanciesCompletedNCT00621244Phase 1/2Results posted
• Carboplatin and Nab-Paclitaxel With or Without Vorinostat in Treating Women With Newly Diagnosed Operable Breast CancerActive, not recruitingNCT00616967Phase 2Results posted
• MK-0518 Intensification And HDAC Inhibition In Depletion Of Resting CD4+ T Cell HIV InfectionTerminatedNCT00614458Phase 2Results posted
• Effect of Valproic Acid Concentration on Photic ResponseCompletedNCT00609245Phase 4Results posted
• Phase IIA Study of the HDAC Inhibitor ITF2357 in Patients With JAK-2 V617F Positive Chronic Myeloproliferative DiseasesCompletedNCT00606307Phase 2Results posted
• Valproic Acid (Depakote[Registered Trademark]) to Treat Autoimmune Lymphoproliferative Syndrome (ALPS)CompletedNCT00605657Phase 1/2Results posted
• Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLCCompletedNCT00602030Phase 1/2Results posted
• Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell LymphomaCompletedNCT00601718Phase 1/2Results posted
• LBH589 in Refractory Myelodysplastic Syndromes (MDS)TerminatedNCT00594230Phase 2Results posted
• Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis)TerminatedNCT00590538Phase 1/2Results posted
• Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate CancerCompletedNCT00589472Phase 2Results posted
• Belinostat (PXD101) to Treat Tumors of the Thymus at an Advanced StageCompletedNCT00589290Phase 2Results posted
• Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GADCompletedNCT00579280Phase 4Results posted
• Trial for Locally Advanced Breast Cancer Using Vorinostat Plus ChemotherapyCompletedNCT00574587Phase 1/2Results posted
• Open Label, Multicentre Trial to Assess Safety and Efficacy of ITF2357 in Active Systemic Juvenile Idiopathic ArthritisCompletedNCT00570661Phase 2Results posted
• A Trial of Panobinostat and Trastuzumab for Adult Female Patients With HER2 Positive Metastatic Breast Cancer (MBC) Whose Disease Has Progressed on or After TrastuzumabTerminatedNCT00567879Phase 1/2Results posted
• Vorinostat After Stem Cell Transplant in Treating Patients With High-Risk LymphomaCompletedNCT00561418Phase 1Results posted
• Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)TerminatedNCT00555399Phase 1/2Results posted
• Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle DisordersCompletedNCT00551200Phase 2Results posted
• LBH589 Treatment for Refractory Clear Cell Renal CarcinomaCompletedNCT00550277Phase 2Results posted
• Study to Evaluate Sodium Phenylbutyrate in Pre-symptomatic Infants With Spinal Muscular AtrophyCompletedNCT00528268Phase 1/2Results posted
• Valproic Acid (Depakote ER) in Patients With Advanced Thyroid CancerTerminatedNCT00525135Phase 2Results posted
• Phase I/II of Oral Vorinostat Combination With Erlotinib in NSCLC Patients With EGFR Mutations With DP After Erlotinib.TerminatedNCT00503971Phase 1/2Results posted
• Study of Oral LBH589 in Adult Participants With Refractory/Resistant Cutaneous T-Cell Lymphoma (CTCL)TerminatedNCT00490776Phase 2Results posted
• Phase IIa Vorinostat (MK0683, Suberoylanilide Hydroxamic Acid (SAHA)) Study in Lower Risk Myelodysplastic Syndromes (0683-064)TerminatedNCT00486720Phase 2Results posted
• Vorinostat, Carboplatin, and Paclitaxel in Treating Patients With Advanced or Metastatic Non-Small Cell Lung CancerCompletedNCT00481078Phase 2Results posted
• Phase I Trial of Vorinostat (MK-0683, SAHA) in Combination With Decitabine in Patients With AML or MDS (MK-0683-055 EXT1)CompletedNCT00479232Phase 1Results posted
• A Clinical Trial of Vorinostat (MK0683, SAHA) in Combination With FDA Approved Cancer Drugs in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)(0683-056)TerminatedNCT00473889Phase 2/3Results posted
• Efficacy and Safety of LBH589 in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Chronic PhaseTerminatedNCT00451035Phase 2Results posted
• Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast PhaseTerminatedNCT00449761Phase 2Results posted
• Efficacy and Safety of LBH589B in Adult Patients With Multiple MyelomaTerminatedNCT00445068Phase 2Results posted
• PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDSCompletedNCT00439673Phase 2Results posted
• Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Types II or IIITerminatedNCT00439569Phase 1/2Results posted
• Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Type ITerminatedNCT00439218Phase 1/2Results posted
• A Trial of Romidepsin for Progressive or Relapsed Peripheral T-cell LymphomaCompletedNCT00426764Phase 2Results posted
• Study of Oral LBH589 in Adult Patients With Refractory Cutaneous T-Cell LymphomaCompletedNCT00425555Phase 2Results posted
• A Study of Carboplatin + Paclitaxel and MK0683 in Patients With Chemotherapy-naive Non-Small Cell Lung Cancer (NSCLC)(0683-066)TerminatedNCT00424775Phase 1Results posted
• Clinical Trial of MK0683 in Combination With FDA Approved Cancer Drugs in Patients With Advanced NSCLC (MK0683-058)CompletedNCT00423449Phase 1Results posted
• A Study of Belinostat + Carboplatin or Paclitaxel or Both in Patients With Ovarian Cancer in Need of Relapse TreatmentCompletedNCT00421889Phase 1/2Results posted
• Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)CompletedNCT00414310Phase 2Results posted
• Naturalistic Study, Comparison of Divalproex Extended Release (ER) and Quetiapine for Adults With Acute Mania or Mixed EpisodesCompletedNCT00397020Phase 4Results posted
• FR901228 in Treating Patients With Relapsed or Refractory Non-Hodgkin's LymphomaTerminatedNCT00383565Phase 2Results posted
• Azacytidine With Valproic Acid Versus Ara-C in Acute Myeloid Leukemia (AML)/ Myelodysplastic Syndrome (MDS) PatientsCompletedNCT00382590Phase 2Results posted
• A Study of Romidepsin (Depsipeptide) in Combination With Gemcitabine in Patients With Pancreatic and Other Advanced Solid TumorsCompletedNCT00379639Phase 1Results posted
• A Study of Oral Suberoylanilide Hydroxamic Acid (Vorinostat) in Patients With Solid Tumors (0683-048)CompletedNCT00373490Phase 1Results posted
• Phase I-II Study of Vorinostat, Paclitaxel, and Bevacizumab in Metastatic Breast CancerCompletedNCT00368875Phase 1/2Results posted
• Phase II Trial of SAHA & Tamoxifen for Patients With Breast CancerCompletedNCT00365599Phase 2Results posted
• PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By SurgeryCompletedNCT00365053Phase 2Results posted
• Vorinostat in Treating Patients With Locally Recurrent or Metastatic Cancer of the UrotheliumTerminatedNCT00363883Phase 2Results posted
• Belinostat in Treating Patients With Myelodysplastic SyndromesCompletedNCT00357162Phase 2Results posted
• PXD101 in Treating Patients With Acute Myeloid LeukemiaCompletedNCT00357032Phase 2Results posted
• Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle DisorderCompletedNCT00345605Phase 2Results posted
• Vorinostat in Treating Patients With Progressive Metastatic Prostate CancerCompletedNCT00330161Phase 2Results posted
• Phase II 5-Azacytidine Plus VPA Plus ATRACompletedNCT00326170Phase 2Results posted
• Vorinostat and Bevacizumab in Treating Patients With Unresectable or Metastatic Kidney CancerCompletedNCT00324870Phase 1/2Results posted
• Vorinostat and Isotretinoin in Treating Patients With Advanced Kidney CancerTerminatedNCT00324740Phase 1/2Results posted
• Belinostat in Treating Patients With Liver Cancer That Cannot Be Removed By SurgeryCompletedNCT00321594Phase 1/2Results posted
• Tolerability and Efficacy of Depakote-extended Release in the ElderlyCompletedNCT00318929Not applicableResults posted
• Azacitidine With or Without Entinostat in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid LeukemiaCompletedNCT00313586Phase 2Results posted
• Does The Addition Of Divalproex Sodium ER To An Atypical Antipsychotic Drug (APD) Improve Cognition And Psychopathology In Outpatients With Schizophrenia (SCH) Or Schizoaffective Disorder (SAD)?CompletedNCT00306475Phase 4Results posted
• Vorinostat in Treating Patients With Acute Myeloid LeukemiaCompletedNCT00305773Phase 2Results posted
• PXD101 in Treating Patients With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's LymphomaCompletedNCT00303953Phase 2Results posted
• Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain TumorsCompletedNCT00302159Phase 2Results posted
• Belinostat in Treating Patients With Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer or Ovarian Low Malignant Potential TumorsCompletedNCT00301756Phase 2Results posted
• Effects of Divalproex Sodium on Food Intake, Energy Expenditure, and Posture AllocationCompletedNCT00287053Phase 4Results posted
• Vorinostat in Treating Patients With Kidney CancerCompletedNCT00278395Phase 2Results posted
• A Phase II Clinical Trial of PXD101 in Patients With Recurrent or Refractory Cutaneous and Peripheral T-Cell LymphomasTerminatedNCT00274651Phase 2Results posted
• Vorinostat in Treating Women Who Are Undergoing Surgery For Newly Diagnosed Stage I -III Breast CancerCompletedNCT00262834Phase 2Results posted
• Vorinostat and Trastuzumab in Treating Patients With Metastatic or Locally Recurrent Breast CancerCompletedNCT00258349Phase 1/2Results posted
• Treatment of Bipolar Mania in Older AdultsCompletedNCT00254488Phase 4Results posted
• Vorinostat in Treating Patients With Low-Grade Non-Hodgkin's LymphomaCompletedNCT00253630Phase 2Results posted
• A Phase I/II Clinical Trial of Vorinostat in Combination With Erlotinib for Patients With Relapsed/Refractory Non-Small-Cell Lung Cancer (0683-025)TerminatedNCT00251589Phase 1/2Results posted
• Valproate Efficacy in Cocaine-Bipolar ComorbidityCompletedNCT00240110Phase 1/2Results posted
• Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma MultiformeCompletedNCT00238303Phase 2Results posted
• Valproic Acid and Carnitine in Patients With Spinal Muscular AtrophyCompletedNCT00227266Phase 2Results posted
• Placebo Controlled Trial of Valproate and Risperidone in Young Children With Bipolar DisordersCompletedNCT00221403Phase 3Results posted
• Divalproex Sodium vs. Placebo in Childhood/Adolescent AutismCompletedNCT00211757Phase 2Results posted
• An Open Label Study Using Consecutive Intravenous Depacon With Oral Depakote ER for the Treatment of Cluster Headaches.CompletedNCT00203242Not applicableResults posted
• Lithium and Divalproex for the Treatment of Comorbid Rapid Cycling Bipolar Disorder and Substance Abuse DisorderCompletedNCT00194129Phase 3Results posted
• Double-blind, Placebo-Controlled Divalproex Sodium ER in Bipolar I or Bipolar II DepressionCompletedNCT00194116Phase 3Results posted
• Valproate in Late Life SchizophreniaCompletedNCT00194025Phase 4Results posted
• Depakote ER in Bipolar DepressionCompletedNCT00186186Phase 4Results posted
• Maintenance Treatment of Bipolar DepressionCompletedNCT00183469Phase 4Results posted
• Risperidone and Divalproex Sodium With MRI Assessment in Pediatric BipolarCompletedNCT00176202Phase 3Results posted

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