Histone Deacetylase Inhibitors: all 1,242 studies that test it
Page 1 of 13. Open to participants first (144), then studies with results posted, then the rest; newest registration first within each.
- BEBT-908 in MEF2D-Rearranged Relapsed/Refractory or MRD-Positive B-Cell Precursor Acute Lymphoblastic LeukemiaRecruitingNCT07854652Phase 1
- VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent GliomaRecruitingNCT07831369Phase 2
- Chidamide Maintenance to Prevent Relapse After Allogeneic Hematopoietic Stem Cell Transplantation in Acute T-Lymphoblastic Leukemia/LymphomaNot yet recruitingNCT07774377Phase 3
- Golidocitinib and Chidamide for Cutaneous T-Cell LymphomaRecruitingNCT07754890Phase 1/2
- The Efficacy of CAPCT in Patients With PTCLNot yet recruitingNCT07746245Phase 2
- Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and OsteosarcomaRecruitingNCT07725380Phase 1/2
- Entinostat Plus Pyrotinib and Endocrine Therapy in Advanced Triple-Positive Breast Cancer After Trastuzumab FailureRecruitingNCT07708194Phase 1/2
- Butyrate or Intensive Lifestyle Modification in Type 1 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver DiseaseNot yet recruitingNCT07684248Not applicable
- A Study of BEBT-908 in Combination With Chemotherapy in Patients With Previously Untreated Peripheral T-Cell Lymphoma (PTCL)Not yet recruitingNCT07676175Phase 2
- Chidamide Monotherapy for Intermediate-to-High-Risk Myelodysplastic SyndromesNot yet recruitingNCT07616336Phase 2
- Lisaftoclax Plus Chidamide and Rituximab in Relapsed or Refractory Diffuse Large B-cell LymphomaNot yet recruitingNCT07601607Phase 1/2
- Sodium Butyrate and Kluyveromyces Marxianus Supplementation in Inflammatory Bowel DiseaseRecruitingNCT07591012Not applicable
- Chidamide Combined With Chemotherapy and Immunotherapy as First-line Treatment for Advanced Intrahepatic CholangiocarcinomaRecruitingNCT07570849Phase 2
- A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed GlioblastomaRecruitingNCT07569042Phase 1/2
- Re-radiotherapy Combined With Chidamide for the Treatment of Recurrent Head and Neck Squamous Cell Carcinoma After RadiotherapyRecruitingNCT07545967Phase 1
- Efficacy and Safety of Chidamide+Sintilimab+Bev as Second-Line Therapy in Advanced Extrapulmonary Neuroendocrine CarcinomaRecruitingNCT07518602Phase 2
- Venetoclax-Azacitidine in Combination With Chidamide and CAG in Fit Older Patients With Acute Myeloid LeukaemiaRecruitingNCT07514936Phase 3
- Venetoclax Combined With CACAG Regimen Versus "3+7" Regimen in the Treatment of Acute Monocytic LeukemiaRecruitingNCT07512700Phase 2
- Chidamide Maintenance for MRD-Positive Double-Expressor DLBCL in First Complete RemissionRecruitingNCT07507318Phase 2
- Genotype-guided Targeted Agents Plus EZH2i for Primary Refractory PTCLNot yet recruitingNCT07493330Phase 1/2
- Chidamide Combination With R-mini CHOP Followed by Chidamide+CD20 Maintenance in Elderly Newly Diagnosed MYC/BCL2+ DLBCLRecruitingNCT07493148Phase 2
- Chidamide for Maintenance Treatment of HBV-infected Diffuse DLBCL in Patients Initially Treated With R-CHOPRecruitingNCT07493109Phase 3
- A Single-arm, Prospective, Phase II Clinical Study of the Combination of Entinostat and Oral Paclitaxel in the Treatment of HR+HER2- Advanced Breast CancerNot yet recruitingNCT07441486Phase 2
- Phase Ib/II Study of Polatuzumab Vedotin in Combination With Rituximab and Chidamide in Newly Diagnosed Elderly Patients With Double-Expressor DLBCLNot yet recruitingNCT07415980Phase 1/2
- A Study of Chidamide Combined With Ivonescimab in the Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) With Acquired Resistance to Immunotherapy and High Yes-associated Protein (YAP) ExpressionRecruitingNCT07412262Phase 2
- CRP Regimen in Treating Elderly Patients With Previously Untreated Double-Positive DLBCLRecruitingNCT07397832Phase 2
- Chidamide in Combination With Toripalimab and Anlotinib in Recurrent/Metastatic Nasopharyngeal Carcinoma.Not yet recruitingNCT07320963Phase 1/2
- Post-transplantation Maintenance Therapy With Cidabenamide in Patients With Intermediate/High-risk AMLRecruitingNCT07304232Phase 2
- BEBT-908 Plus Chemotherapy Treatment for CR MRD-Positive MEF2D-Rearranged and Pre-B Acute Lymphoblastic Leukemia PatientsNot yet recruitingNCT07301138Phase 2
- Entinostat & Chemotherapy for Locally Advanced or Metastatic Bladder CancerNot yet recruitingNCT07261592Phase 1/2
- NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + DinutuximabNot yet recruitingNCT07261241Phase 2
- A Study of ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRCRecruitingNCT07244705Phase 1/2
- A Study of Entinostat in Combination With Fulvestrant for the Treatment of Locally Advanced or Metastatic Breast CancerNot yet recruitingNCT07235618Phase 2
- Valproate for the Treatment of Residual AmblyopiaRecruitingNCT07226141Phase 1/2
- Valproic AcId for Traumatic BRAin INjury TrialNot yet recruitingNCT07166393Phase 2/3
- Venetoclax Combined With Azacitidine, Chidamide, Vindesine, and Dexamethasone in Newly Diagnosed ETP-ALL Like PatientsRecruitingNCT07159620Phase 2
- An Exploratory Evaluation of the Safety and Efficacy of Vorinostat in Pitt Hopkins SyndromeRecruitingNCT07150026Phase 1
- Rett REVOLUTION Trial: An Exploratory Evaluation of the Safety and Efficacy of Vorinostat in Rett SyndromeRecruitingNCT07150013Phase 1
- Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical PatientsRecruitingNCT07144033Not applicable
- Linperlisib Combined With Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell LymphomaNot yet recruitingNCT07139353Phase 1/2
- An Individual Patient, Open Label Study to Use ACER-001 to Treat Combined D,L-2 Hydroxyglutaric Aciduria (C-2HGA)Enrolling by invitationNCT07125066Phase 1
- Golidocitinib Combined With Mitoxantrone Hydrochloride Liposome or Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell LymphomaRecruitingNCT07093710Phase 1/2
- Golidocitinib With Azacitidine and Chidamide in Patients With Peripheral T-cell Lymphoma.Not yet recruitingNCT07081607Phase 2
- Pharmacogenetics-Based Study on Individualized Use of Sodium ValproateRecruitingNCT07046676Phase 4
- A Phase III Clinical Study of Purinostat Mesylate for Injection in Patients With Diffuse Large B-cell LymphomaRecruitingNCT07011056Phase 3
- Vorinostat for Graft-versus-host Disease (GVHD) Prevention in Non-Malignant Adolescent and Young Adults (AYA) PopulationRecruitingNCT06995521Phase 2
- A Clinical Study on the Efficacy and Safety of Fruquintinib in Combination With PD-1 Monoclonal Antibody and Chidamide in Refractory MSS Metastatic Colorectal CancerRecruitingNCT06979908Phase 2
- Study Investigating Intravesical HDAC Inhibition to Improve Response to Immuno-Oncology AgentsRecruitingNCT06963346Phase 1
- QL1706 Plus Chidamide, AG as First-line Treatment for Metastatic Pancreatic CancerRecruitingNCT06951997Phase 2
- Tucidinostat in Combination With CHOP in Newly Diagnosed Peripheral T-Cell Lymphoma With Follicular Helper of T Cell PhenotypeRecruitingNCT06947967Phase 3
- Adjuvant Quisinostat in High-Risk Uveal MelanomaRecruitingNCT06932757Phase 2
- A Multicenter RCT of "3+7" vs Venetoclax + CACAG in Newly Diagnosed Mid/High-Risk AML PatientsRecruitingNCT06928376Phase 2
- Chidamide Plus R-CHOP in Newly Diagnosed Double-Expressor Diffuse Large B-Cell Lymphoma With Other Molecular SubtypesRecruitingNCT06891157Phase 2
- Study Comparing BEBT-908 Combined With R to SOC for the Treatment of Relapsed/Refractory Diffuse Large B-Cell LymphomaRecruitingNCT06792253Phase 3
- Clinical Trial of HG146 Administered to Participants With Adenoid Cystic CarcinomaRecruitingNCT06781567Phase 2
- Dietary Supplements to Treat Radiation-Induced Rectal InjuryRecruitingNCT06776016Phase 2
- Study of Sodium Phenylbutyrate (ACER-001) for the Treatment of Pediatric and Adults Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD)RecruitingNCT06773026Phase 2
- Pharmacokinetics and Safety of Givinostat in DMD Patients Ages From at Least 2 Years to Less Then 6 Years OldRecruitingNCT06769633Phase 2
- MASLD Butyrate Supplementation Treatment Efficacy ReviewEnrolling by invitationNCT06759363Phase 3
- Chidamide Plus Golidocitinib in Relapsed/Refractory Peripheral T-Cell LymphomaNot yet recruitingNCT06757387Phase 1/2
- A Prospective, Randomized, Open, Phase II Clinical Study of Chidamide in Combination with Camrelizumab and Apatinib for Advanced Esophageal CancerNot yet recruitingNCT06745193Phase 2
- Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment ExhaustionRecruitingNCT06739395Phase 2
- ValproIc Acid to Potentiate Anti-EGFR Treatment Efficacy and Prevent/Revert Resistance in Colorectal CancerRecruitingNCT06714357Phase 2
- A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]RecruitingNCT06693284Early Phase 1
- Safety and Efficacy of Fruquintinib Plus Chidamide and Sintilimab in the Third and Later Line Treatment of MSS/pMMR Metastatic Colorectal CancerRecruitingNCT06685276Phase 2
- The NaBu Effect on Menstruation in WomenRecruitingNCT06653426Not applicable
- Na-Phenylbutyrate VAscular TrialNot yet recruitingNCT06645769Early Phase 1
- Glofitamab Combination With Chidamide in Patients With Recurrent/Refractory DLBCLRecruitingNCT06570447Phase 2
- Chidamide and PD-1 Inhibitor Plus Anlotinib for HER2-low Breast Cancer That Has Spread or Cannot be Surgically RemovedNot yet recruitingNCT06547476Phase 2
- A Study Comparing the Efficacy and Safety of Pola-RCHP-X Versus RCHOP-X and Pola-RCHP in Previously Untreated Patients With DLBCLNot yet recruitingNCT06516978Phase 2
- Butyrate Supplementation in Children With Autism Spectrum Disorder (ASD) and Functional Gastrointestinal DisordersRecruitingNCT06514573Not applicable
- A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer PatientsRecruitingNCT06497985Phase 3
- Valproate Versus Propranolol in MigraineRecruitingNCT06485726Phase 4
- Purinostat Mesylate Combined With Pomalidomide Capsules and Low-dose Dexamethasone in Patients With Relapsed or Refractory Multiple MyelomaRecruitingNCT06484829Phase 1/2
- Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AMLRecruitingNCT06451861Phase 2
- Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)RecruitingNCT06448663Not applicable
- Linperlisib Combined With Chidamide in Patients With PTCLRecruitingNCT06421948Phase 1/2
- A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and ToxicityRecruitingNCT06406465Phase 2
- Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid LeukemiaRecruitingNCT06386302Not applicable
- Optimizing Reversal of HIV Latency With Combination TherapyNot yet recruitingNCT06240520Phase 1/2
- A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALLRecruitingNCT06220487Phase 2
- A Phase II Clinical Study of the Efficacy and Safety of Tislelizumab Combined With Fruquintinib and Chidamide in the Treatment of Unresectable or Advanced Microsatellite Stabilized (MSS/pMMR) Colorectal Cancer With Liver MetastasesNot yet recruitingNCT06218888Phase 2
- A Study to Investigate Treatment of HU and VPA, or 6-MP and VPA in Unfit AML/HR-MDS PatientsRecruitingNCT06199557Phase 1/2
- Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate CancerRecruitingNCT06145633Phase 2
- Tucidinostat Plus Apatinib for Advanced OsteosarcomaNot yet recruitingNCT06125171Phase 2
- Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia VeraRecruitingNCT06093672Phase 3
- Zolmitriptane as Prophylaxis for Chilhood MigraineRecruitingNCT06089356Phase 4
- A Prospective Clinical Study of Bridging alloHSCT After Treatment With Obinutuzumab in Combination With Chidamide and Venetoclax in RR Ph-ALL and B-cell Lymphoma PatientsNot yet recruitingNCT06087419Phase 1/2
- Clinical Study of Venetoclax Combined With CACAG Regimen in the Treatment of Relapsed/Refractory Acute Myeloid LeukemiaRecruitingNCT06084819Phase 2
- A Study of Chidamide With AZA in MRD Positive AML After TransplantRecruitingNCT06066905Not applicable
- Sodium Valproate in Patients With Acute Ischemic StrokeRecruitingNCT06020898Phase 2
- Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast CancerRecruitingNCT05983107Phase 2
- Prospective, Single Arm, Single Center Study of Duvelisib Combined With Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma (PTCL)RecruitingNCT05976997Phase 2
- Fimepinostat, Combination HDAC and Pi3-kinase Inhibitor Tumor-Directed Therapy for Cushing DiseaseRecruitingNCT05971758Phase 2
- Chidamide in Combination With Azacitidine, Liposomal Mitoxantrone, and Prednisone (CAMP Regimen) for the Treatment of Previously Untreated Nodal TFH Cell LymphomaRecruitingNCT05958719Phase 2
- Efficacy, Safety and Tolerability of Givinostat in Non-ambulant Patients With Duchenne Muscular DystrophyRecruitingNCT05933057Phase 3
- Combination Regimen With Sodium Valproate for Severe Hemophilia: a Single-arm, Phase 1, Pilot Trial.RecruitingNCT05920512Phase 1/2
- A Study of Chidamide Plus Endocrine in Maintenance Treatment of HR+/HER2- Breast Cancer After First-line ChemotherapyRecruitingNCT05890287Not applicable
- Treatment of Chidamide and Venetoclax for Retinoic Acid and Arsenic Resistant Acute Promyelocytic LeukemiaRecruitingNCT05881265Phase 2
- TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia IIRecruitingNCT05848687Phase 1/2