Histone Deacetylase Inhibitors: all 1,242 studies that test it
Page 2 of 13. Open to participants first (144), then studies with results posted, then the rest; newest registration first within each.
- Chidamide in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (R/R PTCL)RecruitingNCT05833724Phase 2
- Chidamide, Azacitidine Combined With GM Regimen for Relapsed and Refractory DLBCL PatientsRecruitingNCT05823701Phase 2
- Valproic Acid/Simvastatin Plus Gemcitabine/Nab-paclitaxel Based Regimens in Untreated Metastatic Pancreatic Adenocarcinoma PatientsRecruitingNCT05821556Phase 2
- Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal CancerRecruitingNCT05725200Phase 2
- A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent GliomaRecruitingNCT05698524Phase 1
- Chidamide Prevents Recurrence of High-risk AML After Allo-HSCTRecruitingNCT05682755Phase 1/2
- AC-CHOP Versus CHOP in Patients With Previously Untreated PTCL-TFHEnrolling by invitationNCT05678933Phase 3
- Tucidinostat and Nab-paclitaxel in Advanced HR+/HER2- Breast CancerRecruitingNCT05633914Phase 2
- Phase Ⅱ Study of Chidamide in Combination With CHOP in Previously Untreated Peripheral T-Cell Lymphoma With Follicular Helper of T Cell PhenotypeRecruitingNCT05572983Phase 2
- Venetoclax and Azacitidine Combined With Chidamide (VAC) for the Treatment of Newly Diagnosed Acute Monocytic LeukemiaRecruitingNCT05566054Phase 2
- A Umbrella Study in R/R PTCL Guided by Molecular SubtypesRecruitingNCT05559008Phase 1/2
- ChiCGB vs BEAM in High-risk or R/R LymphomasRecruitingNCT05466318Phase 3
- Chidamide in Combination With Abemaciclib and Endocrinotherapy（Doctor's Choice） in Breast Cancer Patients Previously Treated With PalbociclibRecruitingNCT05464173Phase 1/2
- Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing StrategyRecruitingNCT05431595Phase 2/3
- Chidamide Bridging for CAR-T TherapyRecruitingNCT05370547Phase 1/2
- Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell LymphomaRecruitingNCT05348213Phase 2
- Tucidinostat Plus Etoposide in the Treatment of Neuroblastoma in Childhood.RecruitingNCT05338541Phase 1
- Study of Chidamide, Decitabine and Immune Checkpoint Inhibitors in R/R NHL and Advanced Solid TumorsRecruitingNCT05320640Phase 1/2
- Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia RelapseRecruitingNCT05270200Phase 1/2
- The Use of Butyrate Therapy in Pediatric Ulcerative ColitisRecruitingNCT05218850Phase 2
- An Exploratory Study of Surufatinib Combined With Chidamide and Fulvestrant in HR Positive Unresectable Metastatic Breast CancerRecruitingNCT05186545Phase 2
- Tucidinostat Plus PD-1 Inhibitor and Bevacizumab for Advanced Esophagus Cancer, AEG, Gastric CancerRecruitingNCT05163483Phase 2
- Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid TumorsRecruitingNCT05053971Phase 1/2
- Repurposed Drugs to Improve Haematological Responses in Myelodysplastic SyndromesRecruitingNCT04997811Phase 2
- Sintilimab in Combination With Chidamide in Newly Diagnosed ENKTCLRecruitingNCT04994210Phase 2
- Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram SyndromeRecruitingNCT04940572Phase 2
- The Clinical Trial of Chidamide+Decitabine+Camrelizumab Versus Decitabine+Camrelizumab in Anti-PD-1 Antibody Resistant Patients With Classical Hodgkin Lymphoma.RecruitingNCT04514081Phase 2
- Chidamide in Combination With Decitabine in Non-Hodgkin's Lymphoma Relapsed After Chimeric Antigen ReceptorRecruitingNCT04337606Phase 1/2
- Chidamide Combination With Lenalidomide in Patients With Relapsed or Refractory Peripheral T-cell LymphomaRecruitingNCT04329130Phase 2
- Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS MalignanciesRecruitingNCT04308330Phase 1
- Addition of Chidamide to the Combination Treatment of Decitabine Plus Camrelizumab in Combination Treatment Resistant/Relapsed Patients With Classical Hodgkin LymphomaRecruitingNCT04233294Phase 2
- Sintilimab (IBI308) in Combination With Chidamide and Azacitidine in Refractory or Relapsed PTCLNot yet recruitingNCT04052659Phase 2
- A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GlioblastomaRecruitingNCT03970447Phase 2/3
- Study to Evaluate Efficacy and Safety of Oral Abexinostat in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)RecruitingNCT03936153Phase 2
- Tolerability Study of Trichostatin A In Subjects With Relapsed or Refractory Hematologic MalignanciesRecruitingNCT03838926Phase 1
- INFORM2 Study Uses Nivolumab and Entinostat in Children and Adolescents With High-risk Refractory MalignanciesRecruitingNCT03838042Phase 1/2
- Effects of Butyrate Enemas on Postoperative Intestinal Motility Disorders in Hirschsprung's DiseaseNot yet recruitingNCT03660176Phase 3
- A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)RecruitingNCT03592472Phase 3
- Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability StudyRecruitingNCT03373968Phase 2/3
- An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With UstekinumabRecruitingNCT03167437Phase 1/2
- Seizure Treatment in GliomaRecruitingNCT03048084Phase 4
- Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of RecurrenceRecruitingNCT02446431Early Phase 1
- An International Clinical Program for the Diagnosis and Treatment of Children With EpendymomaRecruitingNCT02265770Phase 2/3
- Study of Panobinostat (LBH589) in Patients With Sickle Cell DiseaseRecruitingNCT01245179Phase 1
- Pharmacokinetics, Safety and Tolerability of ITF2357 in Participants With Chronic Hepatic Impairment and With Normal Hepatic FunctionCompletedNCT06736223Phase 1Results posted
- Antiseizure Medication in Seizure Networks at Early Acute Brain InjuryTerminatedNCT06081283Phase 4Results posted
- Givinostat and Metabolites Pharmacokinetics in Urine and Plasma (Part 3)CompletedNCT05860114Phase 1Results posted
- The Potential of Givinostat as DDI Victim in Co-administration P-gp Inhibitor (Part 2)CompletedNCT05845567Phase 1Results posted
- Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate RespondersCompletedNCT05718583Not applicableResults posted
- Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp ActivityCompletedNCT05492318Phase 1Results posted
- A Study of HBI-8000 (Tucidinostat) With Pembrolizumab in Non-Small Cell Lung CancerTerminatedNCT05141357Phase 2Results posted
- Placebo-Corrected Effects of Therapeutic Dose (100 mg) and Supratherapeutic Dose (300 mg) of ITF2357 (Givinostat) and Moxifloxacin on QT/QTC IntervalCompletedNCT04821063Phase 1Results posted
- Non-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)TerminatedNCT04804709Phase 1Results posted
- Comparative Study Between Valproate and Memantine in the Prophylactic Management of Episodic Migraine.CompletedNCT04698525Phase 3Results posted
- Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has SpreadCompletedNCT04631029Phase 1Results posted
- Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell MalignanciesCompletedNCT04447027Phase 1Results posted
- Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional ChondrosarcomaActive, not recruitingNCT04340843Phase 2Results posted
- Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent Ovarian Cancer w Response Prediction By GenomicsTerminatedNCT04315233Phase 1Results posted
- BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)TerminatedNCT04296942Phase 1Results posted
- Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast CancerTerminatedNCT04190056Phase 2Results posted
- Valproic Acid and Dihydroergotamine as Abortive Therapy in Pediatric MigraineTerminatedNCT03885154Phase 2Results posted
- Topical Remetinostat Gel as Neoadjuvant Therapy in Patients With Squamous Cell Carcinoma (SCC)TerminatedNCT03875859Phase 2Results posted
- Study to Assess Safety and Activity of Combination Therapy of VRC07-523LS and Vorinostat on HIV-infected PersonsCompletedNCT03803605Phase 1Results posted
- Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeTerminatedNCT03772925Phase 1Results posted
- Safety and Efficacy of Tenalisib (RP6530) in Combination With Romidepsin in Patients With Relapsed/Refractory T-cell LymphomaCompletedNCT03770000Phase 1/2Results posted
- An Exploratory Study of Pembrolizumab Plus Entinostat in Non-Inflamed Stage III/IV MelanomaCompletedNCT03765229Phase 2Results posted
- Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW)CompletedNCT03689114Phase 4Results posted
- Tinostamustine Conditioning and Autologous Stem CellTerminatedNCT03687125Phase 1/2Results posted
- MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine GliomaCompletedNCT03566199Phase 1/2Results posted
- Study of Entinostat With Nivolumab Plus Ipilimumab in Previously Treated Renal Cell CarcinomaTerminatedNCT03552380Phase 2Results posted
- Study of Ixazomib and Romidepsin in Peripheral T-cell Lymphoma (PTCL)TerminatedNCT03547700Phase 1/2Results posted
- Venetoclax and Romidepsin in Treating Patients With Recurrent or Refractory Mature T-Cell LymphomaCompletedNCT03534180Phase 2Results posted
- Vorinostat (SAHA) in Uterine SarcomaTerminatedNCT03509207Phase 2Results posted
- Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed GlioblastomaCompletedNCT03426891Phase 1Results posted
- Dose Escalation & Expansion Study of Oral VRx-3996 & Valganciclovir in Subjects With EBV+ Lymphoid MalignanciesCompletedNCT03397706Phase 1/2Results posted
- Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors.CompletedNCT03345485Phase 1/2Results posted
- MIBG With Dinutuximab +/- VorinostatCompletedNCT03332667Phase 1Results posted
- A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast CancerCompletedNCT03280563Phase 1/2Results posted
- Study of Pembrolizumab (MK-3475) in Combination With RomidepsinActive, not recruitingNCT03278782Phase 1/2Results posted
- Epigenetic Reprogramming in Relapse/Refractory AMLCompletedNCT03263936Phase 1Results posted
- Panobinostat, Carfilzomib, and Dexamethasone in Patients With Relapsed or Refractory Multiple MyelomaTerminatedNCT03256045Phase 2Results posted
- A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic AdenocarcinomaCompletedNCT03250273Phase 2Results posted
- Clinical Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients With Becker Muscular DystrophyCompletedNCT03238235Phase 2Results posted
- To Determine the Safety of Regorafenib, Hydroxychloroquine, and Entinostat Metastatic Colorectal CancerCompletedNCT03215264Phase 1Results posted
- Study to Evaluate Effects of Vorinostat and HXTC on Persistent HIV-1 Infection in HIV-Infected Subjects Started on Antiretroviral Therapy (ART)CompletedNCT03212989Phase 1Results posted
- Entinostat Neuroendocrine (NE) TumorTerminatedNCT03211988Phase 2Results posted
- Combination Latency Reversal With High Dose Disulfiram Plus Vorinostat in HIV-infected Individuals on ARTTerminatedNCT03198559Phase 1/2Results posted
- Topical Remetinostat in Treating Patient With Cutaneous Basal Cell CancerCompletedNCT03180528Phase 2Results posted
- Ricolinostat in Patients With Painful Diabetic Peripheral NeuropathyCompletedNCT03176472Phase 2Results posted
- An Efficacy and Safety Study Of Pracinostat In Combination With Azacitidine In Adults With Acute Myeloid LeukemiaTerminatedNCT03151408Phase 3Results posted
- A Safety and Efficacy Study of Pracinostat and Azacitidine in Patients With High Risk Myelodysplastic SyndromesTerminatedNCT03151304Phase 2Results posted
- Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.Active, not recruitingNCT03150329Phase 1Results posted
- Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell CarcinomaTerminatedNCT03024437Phase 1/2Results posted
- Medroxyprogesterone Acetate With or Without Entinostat Before Surgery in Treating Patients With Endometrioid Endometrial CancerCompletedNCT03018249Early Phase 1Results posted
- CUDC-907 Treatment in People With Metastatic and Locally Advanced Thyroid CancerTerminatedNCT03002623Phase 2Results posted
- Efficacy and Safety of Oral HBI-8000 in Patients With Relapsed or Refractory Adult T Cell Lymphoma (ATL)CompletedNCT02955589Phase 2Results posted
- Phase 2 Study of Glesatinib, Sitravatinib or Mocetinostat in Combination With Nivolumab in Non-Small Cell Lung CancerTerminatedNCT02954991Phase 2Results posted
- Efficacy and Safety of Oral HBI-8000 in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)CompletedNCT02953652Phase 2Results posted
- Testing the Safety and Efficacy of the Combination of the Antibody Pembrolizumab and Entinostat in Patients With Myelodysplastic Syndrome Who Are Not Responding to Hypomethylating AgentsCompletedNCT02936752Phase 1Results posted
- Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian CancerCompletedNCT02915523Phase 1/2Results posted