Flortaucipir clinical trials
Also written 18F-AV-1451, LY3191748 and Tauvid.
How each study uses flortaucipir is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- 22 Aug 2024 · Tauvid · EMEA/H/C/006064 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
32 studies that test it; most in 2014 (6)
| Year | Studies |
|---|---|
| 2013 | 3 |
| 2014 | 6 |
| 2015 | 6 |
| 2016 | 6 |
| 2017 | 4 |
| 2018 | 2 |
| 2019 | 3 |
| 2020 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 21 · Other 11
Avid Radiopharmaceuticals (20) · Mayo Clinic (5) · Molecular NeuroImaging (2) · University of Southern California (1) · Columbia University (1) · University of Alabama at Birmingham (1) · Eli Radiopharma (1) · Tammie L. S. Benzinger, MD, PhD (1)
Often tested with
Tested in the same studies.
Related medicines
As reviewed, each with the page that says it.
- One of Radiopharmaceuticals source
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 2
Studies that test flortaucipir.
- Dec 2026A Phase I Study of [18F]Flortaucipir PET Imaging in Chinese Subjects: Safety, Pharmacokinetics, Biodistribution, Radiation Dosimetry, and Preliminary Diagnostic EfficacyPhase 1 · Eli Radiopharma
- Mar 2027Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal StudyNot applicable · Mayo Clinic
Studies
Open first, then newest update. How each study uses flortaucipir is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 32
- UAB Alzheimer's Disease Center Core Cohort - Tau Imaging SubstudyRecruitingPhase 1University of Alabama at BirminghamNCT03809351Written as [F-18]AV-1451-PET
- Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal StudyRecruitingNot applicableMayo ClinicNCT02740634Written as F-18 AV 1451
- A Phase I Study of [18F]Flortaucipir PET Imaging in Chinese Subjects: Safety, Pharmacokinetics, Biodistribution, Radiation Dosimetry, and Preliminary Diagnostic EfficacyRecruitingPhase 1Eli RadiopharmaNCT07580703Written as [18F]Flortaucipir Injection
- A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear PalsyRecruitingNot applicableMayo ClinicNCT02605785Written as F-18 AV 1451
- Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's DiseaseRecruitingPhase 4Mayo ClinicNCT03821857Written as 18-F-Flortaucipir
- Longitudinal Multi-Modality Imaging in Progressive Apraxia of SpeechRecruitingPhase 4Mayo ClinicNCT01818661Written as AV-1451
- Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal DementiaCompletedPhase 1Mayo ClinicNCT02736695Written as F-18 AV 1451
- 18F-AV-1451 High Resolution Autopsy StudyCompletedPhase 1Avid RadiopharmaceuticalsNCT02350634Written as Flortaucipir F18
- F 18 T807 Tau PET Imaging of Frontotemporal Dementia (FTD)WithdrawnPhase 2Tammie L. S. Benzinger, MD, PhDNCT02707978Written as F 18 T807
- 18F-AV-1451 PET Imaging in Participants Enrolled in the LEARN StudyCompletedPhase 1University of Southern CaliforniaNCT02850146Written as 18F-AV-1451
- Flortaucipir PET Imaging in Subjects With FTDCompletedPhase 1Avid RadiopharmaceuticalsNCT03040713Written as Flortaucipir F18
- Exploratory Evaluation of Flortaucipir Injection in Healthy Volunteers and Cognitively Impaired SubjectsCompletedEarly Phase 1Avid RadiopharmaceuticalsNCT04474405Written as Flortaucipir F18
- Flortaucipir PET Imaging in the Preclinical, Prodromal and Dementia Phases of Alzheimer's DiseaseCompletedPhase 1Avid RadiopharmaceuticalsNCT04468347Written as Flortaucipir F18
- Flortaucipir 18F PET Imaging in BIOCARD StudyTerminatedPhase 1Avid RadiopharmaceuticalsNCT03052972Written as Flortaucipir F18
- Analysis of 18F-AV-1451 PET Imaging in Cognitively Healthy, MCI, and AD SubjectsCompletedPhase 2/3Avid RadiopharmaceuticalsNCT02016560Written as Flortaucipir F18
- Clinical Evaluation of Flortaucipir F 18CompletedPhase 2Avid RadiopharmaceuticalsNCT02278367Written as Flortaucipir F18
- Tau Imaging in Professional FightersCompletedPhase 1Avid RadiopharmaceuticalsNCT02278354Written as Flortaucipir F18
- A Reader Study to Assess Accuracy and Reliability of Flortaucipir F 18 Positron Emission Tomography (PET) Scan InterpretationCompletedPhase 3Avid RadiopharmaceuticalsNCT03901092Written as flortaucipir F 18
- A Study of Flortaucipir PET in Healthy Volunteers and Cognitively Impaired SubjectsCompletedPhase 1Avid RadiopharmaceuticalsNCT01992380Written as Flortaucipir F18
- 18F-AV-1451 Autopsy StudyCompletedPhase 3Avid RadiopharmaceuticalsNCT02516046Written as Flortaucipir F18
See all 32 studies that test flortaucipir →
Given beside what is tested · 3 — flortaucipir is usual care or a partner of the new treatment
- A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's DiseaseRecruitingPhase 1Eli Lilly and CompanyNCT06297590Written as Flortaucipir F18
- Imaging of Brain Amyloid Plaques in the Aging PopulationEnrolling by invitationPhase 4Mayo ClinicNCT00950430Written as Tau (18-F-AV-1451)
- A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's DiseaseCompletedPhase 1Eli Lilly and CompanyNCT03019536Written as Flortaucipir F18
Codes
What other systems call flortaucipir · ClinicalTrials.gg INT000055
- MeSH (NLM) C0005910087-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) J09QS3Z3WBFLORTAUCIPIRConfirmed NLM, Wikidata
- RxNorm 2571858One source FDA
- Wikidata Q27280989flortaucipirConfirmed NLM, Wikidata
- DrugBank DB15033One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000591008 | 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | J09QS3Z3WB | FLORTAUCIPIR | Confirmed NLM, Wikidata |
| RxNorm | 2571858 | — | One source FDA |
| Wikidata | Q27280989 | flortaucipir | Confirmed NLM, Wikidata |
| DrugBank | DB15033 | — | One source Wikidata |
Also registered as flortaucipir f-18 (UNII T1JP1KYU9O · RxNorm 2372689).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.