BiologicalDrug
Escherichia coli lipopolysaccharide clinical trials
- studies test it
- 13
- open now
- 1
- in phase 3
- 0
- first study started
- 2002
Keep track of what changes. Save the escherichia coli lipopolysaccharide studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Studies by the year they started
13 studies that test it; most in 2018 (3)
| Year | Studies |
|---|---|
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 1 |
| 2006 | 1 |
| 2010 | 1 |
| 2013 | 1 |
| 2014 | 1 |
| 2018 | 3 |
| 2019 | 1 |
| 2021 | 1 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 6
- Phase 2
- 1
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 11
University of North Carolina, Chapel Hill (2) · Janssen Research & Development, LLC (1) · Yale University (1) · Radboud University Medical Center (1) · University of Aberdeen (1) · University of Aarhus (1) · Medical University of Vienna (1) · Laureate Institute for Brain Research, Inc. (1)
Often tested with
Tested in the same studies.
MVA-BN smallpox vaccine (1) · Shingrix (1) · Candida albicans Antigen Injection (1) · GSK3358699 (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1)
Studies
Open first, then newest update. How each study uses escherichia coli lipopolysaccharide is read from its arms, and is right about nine times in ten.
Testing it · 13
- Neural Response to Inflammatory Challenge in Major Depressive DisorderRecruitingPhase 1/2Laureate Institute for Brain Research, Inc.NCT04751331Written as LPS
- A Study Exploring the Use of Vaccine and Antigen Challenges for Immune Monitoring in Healthy ParticipantsCompletedEarly Phase 1Janssen Research & Development, LLCNCT03953196Written as LPS
- Peripheral Benzodiazepine Receptors (PBR28) Brain PET Imaging With Lipopolysaccharide Challenge for the Study of Microglia Function in Alzheimer's DiseaseCompletedEarly Phase 1Yale UniversityNCT04057807Written as LPS
- Brain Biomarker on Inflammation ResponseWithdrawnPhase 1University of Maryland, BaltimoreNCT03271814Written as LPS
- The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor CellsCompletedNot applicableRadboud University Medical CenterNCT05570643Written as LPS
- First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699TerminatedPhase 1GlaxoSmithKlineNCT03426995Written as LPS
- Whey Protein Study - Identification of Sustainable SatietyCompletedNot applicableUniversity of AberdeenNCT02246543Written as LPS
- A Study of Intracellular Signaling in Muscle and Fat Cells During KetosisCompletedNot applicableUniversity of AarhusNCT02157155Written as LPS
- Response of Airway Cells to 20,000 EU of Endotoxin in Normal AdultsTerminatedPhase 1University of North Carolina, Chapel HillNCT00838851Written as Clinical Center Reference Endotoxin (CCRE)
- Inflammatory Markers in Sputum After LPS InhalationStatus unknownNot applicableCentre Hospitalier Universitaire BrugmannNCT01081392Written as LPS
- Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic AdultsCompletedPhase 1University of North Carolina, Chapel HillNCT00839189Written as Clinical Center Reference Endotoxin (CCRE)
- Ethnic Differences in the Inflammatory Response in Systemic InflammationCompletedPhase 1Medical University of ViennaNCT00284869Written as LPS
- Low-Dose Endotoxemia and the Acute Phase ResponseStatus unknownNot applicableHerlev HospitalNCT00197899Written as E. Coli endotoxin
Given in every arm · 2 — escherichia coli lipopolysaccharide is usual care beside what is tested
- A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Inhaled GSK1995057CompletedPhase 1GlaxoSmithKlineNCT01587807Written as LPS
- The Effects of Atazanavir-induced Hyperbilirubinemia During Human EndotoxemiaCompletedNot applicableRadboud University Medical CenterNCT00916448Written as E. coli endotoxin