Edoxaban clinical trials
Also written Lixiana, Savaysa and DU-176b.
How each study uses edoxaban is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the edoxaban studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Approvals
The first approval found in each region, with its record
- United States
- 8 Jan 2015 · SAVAYSA · NDA 206316 (FDA, Drugs@FDA)
- European Union
- 19 Jun 2015 · Lixiana · EMEA/H/C/002629 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
73 studies that test it; most in 2017 (8)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2006 | 2 |
| 2007 | 3 |
| 2008 | 3 |
| 2009 | 3 |
| 2011 | 1 |
| 2012 | 3 |
| 2013 | 3 |
| 2014 | 1 |
| 2015 | 4 |
| 2016 | 4 |
| 2017 | 8 |
| 2018 | 7 |
| 2019 | 8 |
| 2021 | 5 |
| 2022 | 4 |
| 2023 | 4 |
| 2024 | 3 |
| 2025 | 3 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 30 · Other 43
Daiichi Sankyo (14) · Daiichi Sankyo Co., Ltd. (10) · Samsung Medical Center (4) · Herlev and Gentofte Hospital (2) · Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company (2) · Hyewon Chung (1) · Rigshospitalet, Denmark (1) · VarmX B.V. (1)
Often tested with
Tested in the same studies.
Apixaban (15) · Rivaroxaban (12) · Dabigatran (8) · Warfarin (6) · Aspirin (1) · Clopidogrel (1) · Tegoprazan (1) · Dalteparin (1)
Related medicines
As reviewed, each with the page that says it.
- One of Factor Xa inhibitors source
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 2
Studies that test edoxaban.
- Mar 2027The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Venous Thromboembolism (DANNOAC-VTE)Phase 4 · Herlev and Gentofte Hospital
- Oct 2027The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Atrial FibrillationPhase 4 · Herlev and Gentofte Hospital
Studies
Open first, then newest update. How each study uses edoxaban is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 73
- Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ TrialRecruitingPhase 3Sunnybrook Health Sciences CentreNCT07454707Written as Edoxaban 15 mg
- Edoxaban Versus Apixaban in Cancer-Associated Venous ThromboembolismNot yet recruitingPhase 4Samsung Medical CenterNCT07852637Written as edoxaban
- Net Clinical Benefit of Edoxaban Versus Apixaban in Patients With Atrial Fibrillation and Coronary Artery DiseaseRecruitingPhase 4Samsung Medical CenterNCT07753200Written as Edoxaban
- Edoxaban Steady-State PK/PD in Adults With Nephrotic SyndromeNot yet recruitingNot applicablePeking University People's HospitalNCT07116239Written as Edoxaban 60 mg
- Low Dose Edoxaban in Elderly Patients With AF and a History of StrokeNot yet recruitingPhase 2/3National Taiwan University HospitalNCT06900725Written as edoxaban
- DOAC in Patients with Child a or B Liver CirrhosisRecruitingPhase 2Centre Hospitalier Universitaire VaudoisNCT05869591Written as Edoxaban 60 MG [Lixiana]
- EdOxaban in fRagIle Patients With Percutaneous Endoscopic GAstrostoMy and atrIal fIbrIllationRecruitingNot applicableAzienda Ospedaliero Universitaria Maggiore della CaritaNCT06285942Written as Edoxaban
- Left Atrial Appendage Occlusion Versus Novel Oral Anticoagulation for Stroke Prevention in Atrial FibrillationRecruitingNot applicableUniversity of AarhusNCT03642509Written as NOAC
- Evaluate the Efficacy and Safety of Edoxaban on Prevention of Catheter-related Thrombosis (CRT) in Cancer PatientsNot yet recruitingPhase 3Cancer Institute and Hospital, Chinese Academy of Medical SciencesNCT06149533Written as Edoxaban
- MidregiOnal Proatrial Natriuretic Peptide to Guide SEcondary Stroke PreventionRecruitingPhase 3University of ZurichNCT03961334Written as Edoxaban
- Efficacy and Safety of Edoxaban in Patients With Atrial Fibrillation and Mitral StenosisRecruitingPhase 2Sung-Hwan KimNCT05540587Written as Edoxaban
- Single Dose Trial of VMX-C001 in Healthy Subjects With and Without FXa Direct Oral AnticoagulantCompletedPhase 1VarmX B.V.NCT06372483Written as Edoxaban 60 mg Oral Tablet
- EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)CompletedPhase 4Population Health Research InstituteNCT03950076Written as Edoxaban
- AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve ImplantationCompletedPhase 3Oslo University HospitalNCT05035277Written as Edoxaban
- Population Pharmacokinetics of Edoxaban in Chinese Patients With Non-Valvular Atrial FibrillationCompletedPhase 4China National Center for Cardiovascular DiseasesNCT05320627Written as Edoxaban
- A Clinical Trial to Evaluate the Effect of Grapefruit Juice on the PK/PD of EdoxabanActive, not recruitingPhase 1Hyewon ChungNCT07113054Written as Edoxaban 60 MG [Lixiana]
- The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Atrial FibrillationActive, not recruitingPhase 4Herlev and Gentofte HospitalNCT03129490Written as Edoxaban Oral Tablet
- The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Venous Thromboembolism (DANNOAC-VTE)Active, not recruitingPhase 4Herlev and Gentofte HospitalNCT03129555Written as Edoxaban Oral Tablet
- Effects of Edoxaban on Platelet AggregationCompletedPhase 2/3University of Sao PauloNCT05122455Written as Edoxaban
- The Nordic Aortic Valve Intervention Trial 4 (NOTION-4)Active, not recruitingNot applicableRigshospitalet, DenmarkNCT06449469Written as Edoxaban
See all 73 studies that test edoxaban →
Given beside what is tested · 7 — edoxaban is usual care or a partner of the new treatment
- A Healthy Volunteer PK/PD, Safety and Tolerability Study of Second Generation Andexanet AlfaCompletedPhase 1Portola PharmaceuticalsNCT03083704Written as Edoxaban 60 MG
- Study of Intravenous VMX-C001 in Healthy Subjects and in Combination With Selected Direct Oral Anticoagulants in Healthy Older SubjectsCompletedPhase 1VarmX B.V.NCT05152420Written as Edoxaban
- A Healthy Volunteer Pharmacokinetics (PK)/Pharmacodynamics (PD), Safety and Tolerability Study of Andexanet in Healthy Japanese and Caucasian SubjectsCompletedPhase 2Portola PharmaceuticalsNCT03310021Written as Edoxaban
- A Clinical Study to Evaluate the Safety and Pharmacokinetics of CKD-344 in Healthy VolunteersStatus unknownPhase 1Chong Kun Dang PharmaceuticalNCT04867200Written as Lixiana(D006)
- Bioequivalence Study Between "DA-5209 Tab" and "Lixiana Tab"CompletedPhase 1Dong-A ST Co., Ltd.NCT04671316Written as Lixiana 60mg Tab
- A Clinical Study to Evaluate the Safety and Pharmacokinetics of CKD-344Status unknownPhase 1Chong Kun Dang PharmaceuticalNCT04673695Written as Lixiana(D006)
- Study of PER977 Administered to Subjects With Steady State Edoxaban Dosing and Re-anticoagulation With EdoxabanCompletedPhase 2Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.NCT02207257Written as Edoxaban
As the comparator · 2 — what is tested is compared with edoxaban
- Dabigatran vs. Oral Anti-Xa Inhibitors in S. Aureus BacteremiaRecruitingPhase 4McGill University Health Centre/Research Institute of the McGill University Health CentreNCT06650501Written as edoxaban
- Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical TherapyCompletedPhase 4Charite University, Berlin, GermanyNCT03463317Written as Edoxaban
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting1
Codes
What other systems call edoxaban · ClinicalTrials.gg INT005705
- MeSH (NLM) C552171edoxabanConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) NDU3J18APOEDOXABANConfirmed FDA, NLM, Wikidata
- RxNorm 1599538Confirmed FDA, Wikidata
- Wikidata Q21011234edoxabanConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C96539EdoxabanOne source FDA
- DrugBank DB09075One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C552171 | edoxaban | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | NDU3J18APO | EDOXABAN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1599538 | — | Confirmed FDA, Wikidata |
| Wikidata | Q21011234 | edoxaban | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C96539 | Edoxaban | One source FDA |
| DrugBank | DB09075 | — | One source Wikidata |
Also registered as edoxaban tosylate (UNII 32W99UE810 · RxNorm 1599564) and edoxaban tosylate monohydrate (UNII 972203R4EW).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.