Drug
Clofarabine clinical trials
Also written Clolar and Evoltra.
- studies test it
- 146
- open now
- 9
- in phase 3
- 9
- first study started
- 1999
Keep track of what changes. Save the Clofarabine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Combined with it in one product
Studies by the year they started
144 studies that test it; most in 2007 (19)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2002 | 5 |
| 2003 | 4 |
| 2004 | 4 |
| 2005 | 7 |
| 2006 | 10 |
| 2007 | 19 |
| 2008 | 15 |
| 2009 | 14 |
| 2010 | 17 |
| 2011 | 10 |
| 2012 | 11 |
| 2013 | 5 |
| 2014 | 5 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 3 |
| 2018 | 2 |
| 2020 | 3 |
| 2021 | 2 |
| 2023 | 3 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 67
- Phase 2
- 99
- Phase 3
- 9
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 19 · Other 127
M.D. Anderson Cancer Center (28) · Genzyme, a Sanofi Company (15) · St. Jude Children's Research Hospital (10) · Memorial Sloan Kettering Cancer Center (8) · Masonic Cancer Center, University of Minnesota (4) · National Cancer Institute (NCI) (3) · Therapeutic Advances in Childhood Leukemia Consortium (3) · Massachusetts General Hospital (3)
Often tested with
Tested in the same studies.
Cytarabine (35) · Cyclophosphamide (22) · Busulfan (19) · Etoposide (16) · Melphalan (13) · Fludarabine (12) · Daunorubicin (7) · Dexamethasone (7)
Studies
Open first, then newest update. How each study uses Clofarabine is read from its arms, and is right about nine times in ten.
Testing it · 146
- Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/LeukemiaRecruitingPhase 2M.D. Anderson Cancer CenterNCT03136146Written as Clofarabine
- Personalized NK Cell Therapy in CBTRecruitingPhase 2M.D. Anderson Cancer CenterNCT02727803Written as Clofarabine
- Cord Blood Transplantation in Children and Young Adults With Blood CancerRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT07566377Written as Clofarabine
- Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant DisordersRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT04644016Written as Clofarabine
- Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCTRecruitingPhase 2Nantes University HospitalNCT05917405Written as Clofarabine
- Vyxeos® With Clofarabine for Pediatric AMLRecruitingPhase 1Princess Maxima Center for Pediatric OncologyNCT07156435Written as Clofarabine
- Clofarabine Therapy in Locally Advanced or Metastatic Urothelial CarcinomaRecruitingPhase 1/2Ekaterina LaukhtinaNCT07034053Written as Clofarabine
- Phase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn DiseaseNot yet recruitingPhase 1/2Stanford UniversityNCT06986382Written as Clofarabine
- Bisantrene Combination for Resistant AMLRecruitingPhase 2Sheba Medical CenterNCT04989335Written as Clofarabine
- Clofarabine and High-Dose Melphalan Followed by Donor Stem Cell Transplant in Patients With Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Myelodysplastic SyndromesCompletedPhase 1City of Hope Medical CenterNCT00641030Written as clofarabine
- Clofarabine/Ara-C Treatment Combined With Reduced-intensity Conditioning Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia in Primary Treatment FailureCompletedPhase 2Nantes University HospitalNCT01188174Written as Clofarabine
- Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic LeukemiaActive, not recruitingPhase 2City of Hope Medical CenterNCT01885689Written as clofarabine
- Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid LeukemiaTerminatedPhase 2Fred Hutchinson Cancer CenterNCT04994808Written as Clofarabine
- Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related DisordersActive, not recruitingPhase 2Dana-Farber Cancer InstituteNCT02425904Written as Clofarabine
- Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaActive, not recruitingPhase 2/3St. Jude Children's Research HospitalNCT03117751Written as Clofarabine
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive MutationsCompletedPhase 3National Cancer Institute (NCI)NCT02883049Written as Clofarabine
- Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid TumorsCompletedPhase 1National Cancer Institute (NCI)NCT02211755Written as Bortezomib plus Clofarabine
- Safety of Clofarabine With Multiagent Chemotherapy in Childhood Acute Lymphoblastic LeukemiaCompletedPhase 1University Hospital, LilleNCT01279096Written as Clofarabine
- Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched DonorsTerminatedPhase 2Memorial Sloan Kettering Cancer CenterNCT03615105Written as Clofarabine
- Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin LymphomaCompletedPhase 1/2M.D. Anderson Cancer CenterNCT01701986Written as Clofarabine
See all 146 studies that test Clofarabine →
Given in every arm · 10 — Clofarabine is usual care beside what is tested
- Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft TransplantationRecruitingPhase 2Nantes University HospitalNCT06252870Written as Clofarabine
- Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation for AMLTerminatedPhase 1Malika KapadiaNCT05569512Written as Clofarabine
- Allogeneic Hematopoietic Stem Cell Transplantation (AlloSCT) Initial Salvage Therapy for Induction Failure Acute Myeloid Leukemia (AML)CompletedPhase 2M.D. Anderson Cancer CenterNCT02441803Written as Clofarabine
- Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and LymphomaCompletedPhase 2St. Jude Children's Research HospitalNCT01700946Written as clofarabine
- Post Transplant Cyclophosphamide (PTCY) as Sole Graft Versus Host Disease (GVHD) Prophylaxis for Matched Allotransplant: CYRICTerminatedPhase 2Nantes University HospitalNCT03263767Written as Clofarabine
- Busulfan, Fludarabine, Clofarabine With Allogeneic Stem Cell Transplantation for Acute Myeloid LeukemiaCompletedPhase 2M.D. Anderson Cancer CenterNCT00469014Written as Clofarabine
- Pilot Trial of Clofarabine Added to Standard Busulfan and Fludarabine for Conditioning Prior to Allogeneic Hematopoietic Cell TransplantationTerminatedPhase 2University of California, San FranciscoNCT01596699Written as Clofarabine
- HSCT for High Risk Inherited Inborn ErrorsCompletedPhase 2Masonic Cancer Center, University of MinnesotaNCT00383448Written as Clofarabine
- Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or LymphomaTerminatedPhase 2St. Jude Children's Research HospitalNCT02518750Written as Clofarabine
- Clofarabine vs Clofarabine in Plus With Low-Dose Ara-C in Previously Untreated Patients With Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndromes (MDS).CompletedPhase 2M.D. Anderson Cancer CenterNCT00088218Written as Clofarabine
Codes
What other systems call Clofarabine · ClinicalTrials.gg INT006811
- MeSH (NLM) D000077866ClofarabineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 762RDY0Y2HCLOFARABINEConfirmed FDA, NLM, Wikidata
- RxNorm 44151Confirmed FDA, Wikidata
- Wikidata Q5134875clofarabineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C26638ClofarabineOne source FDA
- DrugBank DB00631One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077866 | Clofarabine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 762RDY0Y2H | CLOFARABINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 44151 | — | Confirmed FDA, Wikidata |
| Wikidata | Q5134875 | clofarabine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C26638 | Clofarabine | One source FDA |
| DrugBank | DB00631 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.