Clofarabine: all 146 studies that test it

Page 1 of 2. Open to participants first (9), then studies with results posted, then the rest; newest registration first within each.

• Cord Blood Transplantation in Children and Young Adults With Blood CancerRecruitingNCT07566377Phase 2
• Vyxeos® With Clofarabine for Pediatric AMLRecruitingNCT07156435Phase 1
• Clofarabine Therapy in Locally Advanced or Metastatic Urothelial CarcinomaRecruitingNCT07034053Phase 1/2
• Phase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn DiseaseNot yet recruitingNCT06986382Phase 1/2
• Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCTRecruitingNCT05917405Phase 2
• Bisantrene Combination for Resistant AMLRecruitingNCT04989335Phase 2
• Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant DisordersRecruitingNCT04644016Phase 2
• Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/LeukemiaRecruitingNCT03136146Phase 2
• Personalized NK Cell Therapy in CBTRecruitingNCT02727803Phase 2
• Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AMLTerminatedNCT04002115Phase 2Results posted
• TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated DonorsTerminatedNCT03615144Phase 2Results posted
• Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched DonorsTerminatedNCT03615105Phase 2Results posted
• Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or LymphomaCompletedNCT03096782Phase 2Results posted
• Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive MutationsCompletedNCT02883049Phase 3Results posted
• Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related DisordersActive, not recruitingNCT02425904Phase 2Results posted
• Bridging Study to Eliminate Presence of MRD for Acute Leukemia Before HCTTerminatedNCT02349178Phase 2Results posted
• Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute LeukemiaCompletedNCT02135874Phase 2Results posted
• Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT02085408Phase 3Results posted
• Phase II Clofarabine and Cytarabine for Newly Diagnosed Acute Myeloid LeukemiaTerminatedNCT01960387Phase 2Results posted
• Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic LeukemiaActive, not recruitingNCT01885689Phase 2Results posted
• Decitabine Followed by Clofarabine, Idarubicin, and Cytarabine in Acute LeukemiaCompletedNCT01794702Phase 1/2Results posted
• Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin LymphomaCompletedNCT01701986Phase 1/2Results posted
• A Phase II Open-Label Study of High-Dose Cytarabine and Clofarabine in Adult Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Refractory or Relapsed Acute Lymphoblastic LeukemiaCompletedNCT01656031Phase 2Results posted
• Busulfan/Clofarabine + Allogeneic Stem Cell TransplantationCompletedNCT01643668Phase 2Results posted
• Allogeneic Stem Cell Transplant for CLLTerminatedNCT01629511Phase 1/2Results posted
• Reduced-Intensity Hematopoietic Stem Cell Transplant for High Risk Lysosomal and Peroxisomal DisordersCompletedNCT01626092Not applicableResults posted
• T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic TransplantTerminatedNCT01621477Phase 2Results posted
• Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)CompletedNCT01471444Phase 3Results posted
• Clofarabine-cyclophosphamide as Salvage Therapy for Refractory and Relapsed Acute Lymphoblastic Leukemia (ALL) AdultsCompletedNCT01462253Phase 2Results posted
• NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic LymphomaCompletedNCT01451515Phase 2Results posted
• Clofarabine Plus Low-Dose Cytarabine for Patients With Higher-Risk Myelodysplastic Syndrome (MDS)CompletedNCT01444742Phase 2Results posted
• Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic SyndromeCompletedNCT01289457Phase 1/2Results posted
• Clofarabine and Low-Dose Total-Body Irradiation in Treating Patients With Acute Myeloid Leukemia Undergoing Donor Peripheral Blood Stem Cell TransplantCompletedNCT01252667Phase 2Results posted
• Plerixafor and Clofarabine in Frontline Treatment of Elderly Patients With Acute Myelogenous Leukemia (AML)TerminatedNCT01160354Phase 1/2Results posted
• Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive LeukemiaTerminatedNCT01158885Phase 2Results posted
• HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic MalignanciesCompletedNCT01119066Phase 2Results posted
• Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative NeoplasmCompletedNCT01101880Phase 2Results posted
• Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia.CompletedNCT01041508Phase 1Results posted
• Clofarabine, Idarubicin, and Cytarabine Combination in Acute Myeloid Leukemia (AML) InductionCompletedNCT01025154Phase 2Results posted
• Busulfan Plus Clofarabine Followed by Allogeneic Hematopoietic Stem Cell TransplantationCompletedNCT00990249Phase 2Results posted
• Alemtuzumab and Clofarabine for Relapsed or Refractory Acute Lymphoblastic LeukemiaTerminatedNCT00983528Phase 1/2Results posted
• Treatment of Older Adults With Acute Lymphoblastic LeukemiaCompletedNCT00973752Phase 2Results posted
• S0910 Epratuzumab, Cytarabine, and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic LeukemiaCompletedNCT00945815Phase 2Results posted
• Clofarabine-Melphalan-Alemtuzumab Conditioning in Patients With Advanced Hematologic MalignanciesCompletedNCT00943592Phase 1/2Results posted
• T2007-002 Clofarabine, Etoposide, Cyclophosphamide in Relapsed Acute Myelogenous Leukemia (AML)TerminatedNCT00939653Phase 2Results posted
• A Study of Clofarabine in Older Patients With Acute Myeloid Leukemia (AML) for Whom Chemotherapy Is Not SuitableCompletedNCT00924443Phase 2Results posted
• Decitabine and Clofarabine in Higher Risk Myelodysplastic Syndromes (MDS)CompletedNCT00903760Phase 2Results posted
• Clofarabine and Cytarabine in Treating Patients With Acute Myeloid Leukemia With Minimal Residual DiseaseTerminatedNCT00863434Phase 2Results posted
• Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk MalignanciesCompletedNCT00857389Phase 2Results posted
• Clofarabine and Cytarabine in Treating Older Patients With AML or High-Risk MDSCompletedNCT00839982Phase 1/2Results posted
• Clofarabine and Daunorubicin in Treating Older Patients With Newly Diagnosed Acute Myeloid LeukemiaTerminatedNCT00814164Phase 2Results posted
• Clofarabine Plus Low-Dose Cytarabine Induction and Decitabine Consolidation in Frontline Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)CompletedNCT00778375Phase 2Results posted
• Clofarabine and Temsirolimus in Treating Older Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT00775593Phase 2Results posted
• Clofarabine Bone Marrow CytoreductionCompletedNCT00724009Phase 2Results posted
• Low-dose Oral Clofarabine for the Treatment of IPSS INT-1, INT-2 or HIGH Myelodysplastic Syndromes and Chronic Myelomonocytic LeukemiaTerminatedNCT00708721Phase 1/2Results posted
• Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT00703820Phase 3Results posted
• Clofarabine for Myelodysplastic Syndrome (MDS) Patients Who Failed Vidaza Treatment (tx)TerminatedNCT00700011Phase 2Results posted
• Clofarabine and Rituximab in Treating Patients With Relapsed Non-Hodgkin LymphomaTerminatedNCT00691652Phase 1/2Results posted
• Oral Clofarabine for Relapsed/Refractory Non-Hodgkin LymphomaCompletedNCT00644189Phase 1/2Results posted
• Reduced Intensity AlloTransplant For OsteopetrosisTerminatedNCT00638820Phase 2Results posted
• Clofarabine and Non-Myeloablative Allogeneic Hematopoietic TransplantationTerminatedNCT00626626Phase 1/2Results posted
• Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell TransplantTerminatedNCT00617929Phase 2Results posted
• Clofarabine, Cytarabine, and G-CSF in Treating Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT00602225Phase 1/2Results posted
• Clofarabine, Cytarabine, and Thymoglobulin for Allogeneic TransplantationTerminatedNCT00593645Phase 2Results posted
• Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic LeukemiaCompletedNCT00549848Phase 3Results posted
• A Dose Confirmation Study of Oral Clofarabine for Adult Patients Previously Treated for Myelodysplastic Syndromes (MDS)CompletedNCT00531232Phase 2Results posted
• Clofarabine, Cytarabine, and G-CSF in Treating Patients With Myelodysplastic SyndromesTerminatedNCT00503880Phase 1/2Results posted
• Clofarabine, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk and/or Advanced Hematologic Cancer or Other DiseaseCompletedNCT00423514Phase 1/2Results posted
• 2 Arm Study of Clofarabine IV in MDS PatientsCompletedNCT00422032Phase 2Results posted
• Clofarabine in Treating Patients With T-Cell or Natural Killer-Cell Non-Hodgkin's Lymphoma That Has Relapsed or Not Responded to Previous TreatmentCompletedNCT00416351Phase 1/2Results posted
• Clofarabine and Cyclophosphamide Combination in Acute Lymphoblastic Leukemia PatientsCompletedNCT00412243Phase 1/2Results posted
• A Study of Clofarabine for Older Patients With Newly Diagnosed Acute Myelogenous Leukemia (AML) (CLASSIC II)CompletedNCT00373529Phase 2Results posted
• Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic LeukemiaCompletedNCT00372619Phase 1/2Results posted
• S0530 Cytarabine and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic LeukemiaCompletedNCT00337168Phase 2Results posted
• A Study of Clofarabine and Cytarabine for Older Patients With Relapsed or Refractory Acute Myelogenous Leukemia (AML)(CLASSIC I)CompletedNCT00317642Phase 3Results posted
• A Study of Clofarabine in Combination With Etoposide and Cyclophosphamide in Children With Acute Leukemias.CompletedNCT00315705Phase 1/2Results posted
• Oral Clofarabine Study in Patients With Myelodysplastic SyndromeCompletedNCT00299156Phase 2Results posted
• Natural Killer (NK) Cell Transplantation for AMLCompletedNCT00187096Not applicableResults posted
• Clofarabine for Relapsed or Refractory T-Cell or B-Cell Non-Hodgkin Lymphoma (NHL)CompletedNCT00156013Phase 1/2Results posted
• Clofarabine Combinations in Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS) and Myeloid Blast Phase Chronic Myeloid Leukemia (CML)CompletedNCT00067028Phase 2Results posted
• Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid LeukemiaTerminatedNCT04994808Phase 2
• Vorinostat and Combination Chemotherapy Before Donor Stem Cell Transplantation for the Treatment of Relapsed Aggressive B-cell or T-cell Non-Hodgkin LymphomaWithdrawnNCT04220008Phase 2
• Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaActive, not recruitingNCT03117751Phase 2/3
• Clofarabine in Chinese Pediatric Patients With Refractory or Relapsed Acute Lymphoblastic LeukemiaCompletedNCT02544789Phase 2
• Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid TumorsCompletedNCT02211755Phase 1
• Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell TransplantCompletedNCT02083250Phase 1
• Bendamustine Hydrochloride, Clofarabine, and Etoposide in Treating Younger Patients With Relapsed or Refractory Hematologic MalignanciesCompletedNCT01900509Phase 1
• Mitoxantrone and Clofarabine for Treatment of Recurrent NHL or Acute LeukemiaCompletedNCT01842672Phase 1/2
• Clofarabine for Langerhans in PediWithdrawnNCT01796405Phase 2
• Clofarabine, Cyclophosphamide and Etoposide for Minimal Residual Disease Positive Acute LeukemiaWithdrawnNCT01677949Phase 2
• Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid LeukemiaCompletedNCT01629082Phase 1
• Dose Escalation of Clofarabine in Combination With Cytarabine and Idarubicin as Induction Therapy in High Risk AMLStatus unknownNCT01534702Phase 1/2
• Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic Stem Cell Transplant Without Related HLA-MatchTerminatedNCT01500161Phase 2
• Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic MalignanciesCompletedNCT01471067Phase 1
• ClAraC or FLAMSA Followed by Stem Cell Transplantation to Treat High Risk AML or Advanced MDSStatus unknownNCT01423175Phase 2
• Clofarabine Pre-conditioning With Allogeneic Transplant for Acute Myeloid Leukaemia (AML)CompletedNCT01422603Phase 1/2
• Clove In The Treatment Of Relapsed Or Resistant Acute Leukemia In ChildrenCompletedNCT01385891Phase 2/3
• Study of Clofarabine in Combination With Low Dose Cytarabine to Treat Myelodysplastic SyndromesWithdrawnNCT01302106Phase 2
• Clofarabine Salvage Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)CompletedNCT01295307Phase 2
• Safety of Clofarabine With Multiagent Chemotherapy in Childhood Acute Lymphoblastic LeukemiaCompletedNCT01279096Phase 1

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