Ankyloglossia clinical trials

The registry lists 28 studies for Ankyloglossia across more than 10 countries. 8 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.

Studies

Recruiting first, then most recently updated. Showing 28 of 28 — search for more.

• Long-term Follow-up of Infant Frenotomy/Frenectomy Through Early ChildhoodEnrolling by invitationNCT071109481 country
• SNIP follow-on Case Series Using v3 DeviceNot yet recruitingNCT07796165Not applicable1 country
• Ankyloglossia and BreastfeedingNot yet recruitingNCT077575031 country
• The Impact of Post-Frenotomy Massages on Ankyloglossia Recurrence and Feeding OutcomesRecruitingNCT07738185Not applicable1 country
• Effectivity of P1821, a Novel Tongue Strengthening and Endurance Enhancing Speech Flow ExerciseNot yet recruitingNCT07719582Not applicable1 country
• Healing Efficacy of Diode Laser in Lingual FrenectomyRecruitingNCT07557875Not applicable1 country
• Post-Procedural Manual Manipulation for Infant AnkyloglossiaRecruitingNCT06830148Not applicable1 country
• Frenuloplasty for Speech and Myofunctional OutcomesNot yet recruitingNCT06089629Not applicable
• Tongue Mobility in Patients With Ankyloglossia Following FrenectomyCompletedNCT068565641 country
• Case Series of Infants With Anterior Ankyloglossia Being Treated by the Sublingual Neonatal Incision Platform DeviceActive, not recruitingNCT07655895Not applicable1 country
• Ankyloglossia and Its Effects on Breastfeeding, Feeding and Speech Disorders. A Prospective Study From Birth to 4 Years of Age.Active, not recruitingNCT075127651 country
• Lingual Frenulum in Newborn Infants (LINNE)Active, not recruitingNCT05560750Not applicable1 country
• Breastfeeding Duration and Tongue-tie in Neonates.CompletedNCT05946590Not applicable1 country
• Use of Inhaled Colostrum to Control Pain in Neonatal Frenotomy and Comparison to Inhaled Lavender Essential OilCompletedNCT06869902Not applicable1 country
• Evaluation of the Effects of Tongue-Tie and Upper Lip-TieCompletedNCT068264821 country
• Physiotherapy in the Treatment of Breastfeeding DifficultiesCompletedNCT05843279Not applicable1 country
• The Effect of Pre-emptive Analgesia on the Postoperative Pain in Children Undergoing Pediatric Stomatology Day SurgeriesCompletedNCT05878262Not applicable1 country
• Dedicated Lactation Support in Infants With Tongue - Tie; a Randomised Control TrialWithdrawnNCT05135481Not applicable1 country
• Analgesic Effect of Inhaled Lavender Essential Oil for Clipping of Tongue-tiesCompletedNCT04877392Not applicable1 country
• The Impact of Lingual Frenotomy on Bottle Feeding MechanicsCompletedNCT03793413Not applicable1 country
• Comparison Among Propofol, Alfentanil and Rocuronium as Adjunct to Sevoflurane Anesthesia for Endotracheal Intubation in Children With FrenectomyCompletedNCT01550354Not applicable1 country
• Incidence of Short Sublingual Frenulum in Newborns at the Hospital Nostra Senyora de Meritxell.CompletedNCT047039461 country
• The Use of Lavender vs Vanilla Essential Oil as Complementary Analgesia for Frenotomy in Healthy NewbornsStatus unknownNCT04867824Not applicable
• The Scope of Tongue-tie in Norway: Its Prevalence and Consequences for Child HealthStatus unknownNCT04056936
• Prospective Evaluation of Lingual Frenotomy in Newborns With Simultaneous Lip Tie for the Relief of Breastfeeding Pain.CompletedNCT02141243Not applicable1 country
• Anterior Lingual Frenectomy is Inadequate in Improving Breastfeeding Outcomes: a Prospective Cohort StudyCompletedNCT02936518Not applicable
• Breastfeeding Improvement Following Tongue-tie and Lip-tie ReleaseCompletedNCT02642133Not applicable
• Use of Topical Benzocaine for Analgesia in Lingual Frenotomy of the NewbornTerminatedNCT01274247Phase 1/21 country