DrugCombination product
Lumefantrine clinical trials
Also written LUM566.
- studies test it
- 18
- open now
- 0
- in phase 3
- 3
- first study started
- 2004
How studies write it
Studies that test it under each name
Studies by the year they started
17 studies that test it; most in 2012 (3)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 1 |
| 2008 | 1 |
| 2009 | 1 |
| 2011 | 1 |
| 2012 | 3 |
| 2014 | 1 |
| 2016 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 7
- Phase 2
- 1
- Phase 3
- 3
- Phase 4
- 8
What it is tested for
Each study’s main condition, where its own words name it.
- Malaria
- 12
Who runs them
Industry 6 · Other 12
Novartis Pharmaceuticals (4) · University of California, San Francisco (2) · University of Cape Town (2) · Centers for Disease Control and Prevention (1) · Epicentre (1) · Thierry Buclin (1) · GlaxoSmithKline (1) · Universiteit Antwerpen (1)
Often tested with
Tested in the same studies.
Artemether (14) · Artesunate (3) · Amodiaquine (3) · Ganaplacide (3) · Efavirenz (3) · Midazolam (1) · Repaglinide (1) · Dextromethorphan (1)
Studies
Open first, then newest update. How each study uses Lumefantrine is read from its arms, and is right about nine times in ten.
Testing it · 18
- Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum MalariaTerminatedPhase 2/3Novartis PharmaceuticalsNCT04300309Written as artemether:lumefantrine (2.5 mg:30 mg)
- Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in LiberiaCompletedPhase 4Centers for Disease Control and PreventionNCT06300970Written as Artemether+Lumefantrine (AL)
- Drug-drug Interaction Study of Ganaplacide and Lumefantrine With EfavirenzCompletedPhase 1Novartis PharmaceuticalsNCT05330273Written as Lumefantrine
- Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and DolutegravirCompletedPhase 1Novartis PharmaceuticalsNCT05236530Written as Lumefantrine
- Drug-drug Interaction Study of Ganaplacide and Lumefantrine With ItraconazoleCompletedPhase 1Novartis PharmaceuticalsNCT05084651Written as Lumefantrine
- Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During PregnancyCompletedPhase 4EpicentreNCT00495508Written as artemether / lumefantrine
- Longitudinal Antimalarial Combinations in UgandaCompletedPhase 3University of California, San FranciscoNCT00123552Written as Artemether+Lumefantrine
- Lumefantrine in Venous Plasma Versus Dried Capillary Blood SpotCompletedPhase 4Thierry BuclinNCT02742285Written as Artemether + lumefantrine
- A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine TetraphosphateCompletedPhase 1GlaxoSmithKlineNCT02184637Written as Artemether + Lumefantrine
- Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated MalariaCompletedPhase 3Universiteit AntwerpenNCT01374581Written as Artemether/Lumefantrine
- Pharmacology of Antimalarial Therapy With or Without Antiretroviral TherapyTerminatedPhase 4International Maternal Pediatric Adolescent AIDS Clinical Trials GroupNCT01728961Written as Artemether/Lumefantrine (AL)
- Parasite Clearance Time and Time to Recurrent Infection Following Treatment With Artemether/LumefantrineCompletedPhase 4Muhimbili University of Health and Allied SciencesNCT01998295Written as Artemether/lumefantrine
- Interaction Between Etravirine or Darunavir/Ritonavir and Artemether / LumefantrineCompletedPhase 1Janssen Pharmaceutica N.V., BelgiumNCT01876966Written as artemether/lumefantrine
- Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug CombinationsCompletedPhase 1Fran AweekaNCT00697892Written as artemether/lumefantrine
- Drug Interaction Study Between Antimalarial and Anti-HIV MedicationsCompletedPhase 1University of California, San FranciscoNCT00266058Written as Lopinavir/Ritonavir, Efavirenz, Artemether/lumefantrine
- Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected AdultsCompletedPhase 4University of Cape TownNCT00790881Written as Artemether/Lumefantrine
- Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected AdultsCompletedPhase 4University of Cape TownNCT00869700Written as Artemether/Lumefantrine
- Ototoxicity of Artemether / Lumefantrine (Coartem) and Other AntimalarialsCompletedPhase 4Jimma UniversityNCT00451139Written as artemether/lumefantrine
Given in every arm · 4 — Lumefantrine is usual care beside what is tested
- Investigating the Pharmacology of Tafenoquine in Papua New Guinean Children With Uncomplicated MalariaNot yet recruitingPhase 4Curtin UniversityNCT07403643Written as Artemether + Lumefantrine
- A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)CompletedPhase 1Merck Sharp & Dohme LLCNCT06294912Written as Artemether/lumefantrine
- Study of Malaria Vaccine RTS,S/AS01E in Plasmodium Falciparum-infected and Uninfected Adults Pre-treated With Anti-malarial TherapyCompletedPhase 2PATHNCT04661579Written as Artemether / Lumefantrine
- Ivermectin-artemisinin Combination Therapy for Eradication of MalariaStatus unknownPhase 4Makerere UniversityNCT05605925Written as Artemether/lumefantrine
As the comparator · 3 — what is tested is compared with Lumefantrine
- Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-LumefantrineCompletedPhase 2/3University of IbadanNCT05192265Written as Antimalarials, Artemether + Lumefantrine
- Antioxidant Micronutrients in MalariaCompletedPhase 3University of Lagos, NigeriaNCT01152931Written as Lumefantrine + Artemether
- Randomised Efficacy Study of Two Artemether-Lumefantrine Oral Formulations for the Treatment of Uncomplicated P. Falciparum MalariaCompletedPhase 4Dafra PharmaNCT00529867Written as Artemether/lumefantrine tablets
Codes
What other systems call Lumefantrine · ClinicalTrials.gg INT006816
- MeSH (NLM) D000078102LumefantrineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) F38R0JR742LUMEFANTRINEConfirmed FDA, NLM, Wikidata
- RxNorm 847728Confirmed FDA, Wikidata
- Wikidata Q904464lumefantrineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C81541LumefantrineOne source FDA
- DrugBank DB06708One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000078102 | Lumefantrine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | F38R0JR742 | LUMEFANTRINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 847728 | — | Confirmed FDA, Wikidata |
| Wikidata | Q904464 | lumefantrine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C81541 | Lumefantrine | One source FDA |
| DrugBank | DB06708 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.