Analgesics, Non-Narcotic: all 3,330 studies that test it

Page 15 of 34. Open to participants first (511), then studies with results posted, then the rest; newest registration first within each.

• Dexmedetomidine in Obturator Nerve Block as an Analgesic in Transurethral SurgeriesCompletedNCT06229054Early Phase 1
• Delta-8-THC vs. Delta-9-THC on Simulated Driving PerformanceCompletedNCT06218550Phase 1
• Dexmedetomidine Versus Ketofol for Moderate Sedation in Endoscopic Retrograde CholangiopancreatographyCompletedNCT06212401Phase 4
• Dexmedetomidine Versus Fentanyl on Postoperative Analgesic Profile in Laparoscopic Sleeve GastrectomyCompletedNCT06186895Not applicable
• Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During BronchoscopyCompletedNCT06185127Phase 3
• Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nuromol® Tablets (200mg Ibuprofen/ 500mg Paracetamol)CompletedNCT06180070Phase 1
• Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR)CompletedNCT06176196Phase 2
• A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy AdultsCompletedNCT06173596Phase 1
• Effect of Dexmedetomidine vs Esmolol or Placebo on Cerebral Hemodynamics in Septic ShockCompletedNCT06169475Not applicable
• Comparison of Efficacy Between Combination of Amitriptyline-propranolol and Pizotifen for Migraine Prophylaxis.Active, not recruitingNCT06158230Phase 2
• Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic MelanomaCompletedNCT06151847Phase 2
• Comparison of Perioperative Conscious Sedation During Endovascular Thrombectomy in Acute Ischemic StrokeCompletedNCT06139692Phase 4
• Pilot Study of Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial DysautonomiaActive, not recruitingNCT06128356Phase 2
• The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKACompletedNCT06112548Not applicable
• Evaluation of the Efficacy and Safety of Interleucin-2 Combined With PD-1 Monoclonal Antibody and CAPOX in Preoperative Neoadjuvant Therapy for Mid-low Locally Advanced Rectal Cancer - a Single-center, Single-arm, Open-label Clinical TrailCompletedNCT06108596Phase 2
• Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress MarkerCompletedNCT06098209Not applicable
• Hypotensive Anesthesia for Orthognathic SurgeryCompletedNCT06093893Phase 4
• Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis SurgeryCompletedNCT06086431Phase 4
• Intranasal Dexmedetomidine Versus Intravenous Dexmedetomidine for Improving Quality of Endoscopic Sinus SurgeryStatus unknownNCT06081933Phase 4
• A Trial Investigating the Pain-relieving Properties of Lu AG06474 in Healthy Adult ParticipantsCompletedNCT06077786Phase 1
• Heamodynamic Effects of Paracetamol in Septic Shock PatientsCompletedNCT06076980Phase 4
• Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and CarbamazepineCompletedNCT06071442Phase 1
• "Management of Low Back Pain in the Emergency Department With Different Analgesic Dosages"CompletedNCT06064175Phase 4
• Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis PatientsCompletedNCT06061575Phase 4
• Amantadine Therapy for Cognitive Impairment in Long COVIDCompletedNCT06055244Phase 2
• Regional AnaesthesiaCompletedNCT06055101Not applicable
• Combined Cerebrolysin and Amantadine Sulfate Administration for Patients With Traumatic Brain Injury in the ICUCompletedNCT06052787Phase 3
• Dexmedetomidine Infusion During Laparoscopic AdrenalectomyCompletedNCT06037135Not applicable
• Oral Dronabinol-HIVActive, not recruitingNCT06034314Phase 1
• Evaluation of Broccoli Seed and Sprout Extract for Detoxification of Carcinogens in FirefightersActive, not recruitingNCT06009926Phase 2
• A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy ParticipantsCompletedNCT06005688Phase 1
• Effects of Intrathecal Dexmedetomidine as an Adjuvant to Low Dose Hyperbaric 0.5% BupivacaineCompletedNCT05993975Phase 4
• Effect of Dexmedetomidine on the Quality of Recovery in Parturients Undergoing Elective Caesarean SectionsCompletedNCT05991466Phase 4
• Comparison of Efficacy of Bupivacaine in Supraclavicular Block With or Without DexmedetomidineCompletedNCT05991375Phase 4
• Paracetamol Plus Tramadol Versus Fentanyl in Day Case SurgeriesCompletedNCT05990686Phase 4
• Intraperitoneal Dexamethasone, Dexmedetomidine, and Dexamethasone-Dexmedetomidine Combination on Postoperative Nausea and Vomiting After Laparoscopic CholecystectomyCompletedNCT05988671Phase 3
• Oral Medications for the Management of Acute Migraine Headache in the Emergency DepartmentWithdrawnNCT05983354Not applicable
• Caudal Ropivacaine With or Without Dexmedetomidine for Post Operative AnalgesiaCompletedNCT05979558Not applicable
• The Effect of Low-dose Interleukin-2 on the Immune Landscape of Human Atherosclerotic Plaques at Single Cell Resolution.Active, not recruitingNCT05975554Not applicable
• Dark Chocolate, Coconut Water, and Ibuprofen in Managing Primary DysmenorrheaCompletedNCT05971186Phase 2
• Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal SurgeryWithdrawnNCT05965492Phase 3
• A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult ParticipantsCompletedNCT05965219Phase 1
• Dexmedetomidine Versus Dexmedetomidine with Ketamine in Mechanically Ventilated ARDS PatientsCompletedNCT05951387Phase 4
• Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep QualityCompletedNCT05950646Phase 4
• Dexmedetomidine or Lidocaine for Lessening the Hemodynamic Responses to Laryngoscopy and IntubationCompletedNCT05941767Not applicable
• A Study to Assess the Effect of Multiple Doses of Itraconazole, Gemfibrozil, or Carbamazepine on BMS-986278 in Healthy ParticipantsCompletedNCT05932303Phase 1
• Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible PulpitisCompletedNCT05927922Phase 1
• EASE (Efficacy of ATX01 Study in Erythromelalgia)CompletedNCT05917912Phase 2
• Nasal Packing Versus Intravenous Dexmedetomidine in Turbinate SurgeriesCompletedNCT05911776Phase 4
• Ibuprofen Versus Ketorolac For Postoperative Pain Relief After Cesarean SectionCompletedNCT05907993Phase 4
• Intrathecal Dexmedetomidine to Decrease Postoperative Nausea and Vomiting and Shivering.CompletedNCT05892705Phase 4
• Virtual Reality vs Nitrous Oxide in Pediatric DentistryCompletedNCT05890898Not applicable
• Comparisons Between Dexmedetomidine and Magnesium Sulfate in Controlled Hypotension During Rhinoplasty SurgeriesCompletedNCT05880693Phase 1
• The Effect of Pre-emptive Analgesia on the Postoperative Pain in Children Undergoing Pediatric Stomatology Day SurgeriesCompletedNCT05878262Not applicable
• To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With DiarrheaCompletedNCT05867550Phase 4
• Dexmedetomidine in Non-intubated VATSCompletedNCT05863416Phase 4
• A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy ParticipantsCompletedNCT05860933Phase 1
• Morphine IV vs Paracetamol IV in Neonates and Infants After Cardiac SurgeryCompletedNCT05853263Not applicable
• A Study to Evaluate the Effect of Food on the Pharmacokinetics of VX-548CompletedNCT05851157Phase 1
• Opioid-sparing Effect of Intranasal DexmedetomidineCompletedNCT05848505Not applicable
• A Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With PainCompletedNCT05844995Phase 1
• NSAID Use After Robotic Partial NephrectomyActive, not recruitingNCT05842044Phase 2
• DEXMEDETOMIDINE in NORMAL VAGINAL DELIVERYStatus unknownNCT05840328Phase 4
• Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly PatientsTerminatedNCT05834569Phase 4
• The Effect of Dexmedetomidine, Melatonin and PregabalinStatus unknownNCT05829148Early Phase 1
• The Effect of Intraoperative Infusion of Dexmedetomidine Versus Low Dose KetamineStatus unknownNCT05828199Phase 1
• Open-label Trial to Evaluate the Effect Carbamazepine on Darigabat Pharmacokinetics in Healthy Adult ParticipantsCompletedNCT05824143Phase 1
• A Study to Evaluate the Effect of VX-548 on the QT/QTc Interval in Healthy ParticipantsCompletedNCT05818852Phase 1
• Efficacy of Adding Dexmedetomidine in Ultrasound-guided Intermediate Cervical Plexus Block for Thyroidectomy SurgeryCompletedNCT05814744Not applicable
• Intravenous Dexmedetomidine for Emergence Delirium in Pediatric PatientStatus unknownNCT05813106Phase 4
• Influence of Sedation Strategies on Hospital LOS and ICU LOS in Patients Cardiac SurgeryCompletedNCT05809518Not applicable
• Intravenous Ibuprofen Versus Ketorolac in Bariatric SurgeryStatus unknownNCT05801900Not applicable
• Opioid Sparing Analgesia Continuous Intraoperative Infusion of Dexmedetomidine Versus Lidocaine for Laparoscopic CholecystectomyCompletedNCT05788393Phase 4
• Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia RepairStatus unknownNCT05786833Not applicable
• Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or PlaceboStatus unknownNCT05785689Phase 4
• IV Ibuprofen vs Ketorolac in Post Operative Pain in Colorectal Cancer Surgeries in Obese PatientCompletedNCT05782608Not applicable
• Dexmedetomidine for Intermittent Epidural Boluses Versus Continuous Epidural Infusion for Labour Epidural AnalgesiaStatus unknownNCT05781854Phase 2/3
• Effect of Dexmedetomidine on Left Ventricular Function in Coronary Artery Bypass Graft Surgery OutcomeCompletedNCT05778305Early Phase 1
• Effect of Dexmedetomidine As Adjuvant to Ropivacaine for Brachial Plexus BlockCompletedNCT05767827Not applicable
• Nebulized Dexmedetomidine VS ODF Melatonin for Peri Operative Anxiety and Emergence Agitation in Pediatric Day SurgeryStatus unknownNCT05766436Not applicable
• Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Treatment in Spinal SurgeryCompletedNCT05764707Phase 2
• Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial CraniotomyStatus unknownNCT05763836Phase 4
• Topiramate, Amitriptyline Monotherapy and Combination Therapy in Migraine ProphylaxisStatus unknownNCT05759845Phase 4
• Efficacy of Parecoxib Combined With Paracetamol in MastectomyStatus unknownNCT05757388Not applicable
• Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation of CT Guided Bone BiopsyCompletedNCT05752903Phase 4
• A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.Status unknownNCT05751304Not applicable
• Intravenous Ibuprofen Postoperative Analgesia After Abdominal HysterectomyActive, not recruitingNCT05750264Phase 2
• Dexmedetomidine Versus Magnesium Sulphate in Patients Undergoing Craniotomy for Deeply Settled Intracranial TumoursStatus unknownNCT05743725Not applicable
• Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee OsteoarthritisWithdrawnNCT05742763Phase 1/2
• Effects of Dexmedetomidine/Lidocaine/Intrathecal Morphine on Cancer Metastasis Biomarker After Colorectal SurgeryCompletedNCT05742438Not applicable
• Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep QualityCompletedNCT05732064Phase 4
• Dexmedetomidine Infusion and Surgical Pleth Index In PediatricsCompletedNCT05727969Not applicable
• A Comparative Evaluation of Nebulized Dexmedetomidine and Nebulized Ketamine as a Premedication in Pediatric SurgeriesCompletedNCT05719506Phase 4
• Mini-dose Esketamine-dexmedetomidine Supplemented Analgesia and Long-term OutcomesCompletedNCT05718544Phase 4
• Prevention of Shivering After Spinal AnesthesiaCompletedNCT05718011Phase 4
• N2O for Acute Suicidality and Depression in the EDWithdrawnNCT05710887Phase 2
• Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Renal ImpairmentCompletedNCT05704556Phase 1
• TAP Using Dexmedetomidine and Ropivacaine for Cesarean Section AnalgesiaCompletedNCT05700045Not applicable
• Intranasal Dexmedetomidine for Adult Patients Undergoing Phacoemulsification Cataract SurgeryStatus unknownNCT05698758Not applicable
• Dexmedetomidine-Ropivacine Versus Sufentanil-Ropivacaine for Epidural Labor AnalgesiaCompletedNCT05698407Phase 4

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