Analgesics, Non-Narcotic: all 3,330 studies that test it
Page 1 of 34. Open to participants first (511), then studies with results posted, then the rest; newest registration first within each.
- Evaluation of the Effect of Amantadine in the Prevention of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer PatientsNot yet recruitingNCT07889115Phase 2
- Dexmedetomidine as an Adjuvant to Greater Auricular Nerve Block in Middle Ear SurgeriesRecruitingNCT07878533Phase 2
- Dexmedetomidine Use for Greater Occipital Nerve Block in Pediatric Posterior Fossa Tumor Surgery.RecruitingNCT07878156Phase 3
- Ketadex Versus Ketofol for Adult Procedural Sedation in the Emergency Department.Not yet recruitingNCT07874919Phase 4
- Suzetrigine for Analgesiain Arthroscopic Rotator Cuff RepairNot yet recruitingNCT07866638Phase 4
- Suzetrigine in TKARecruitingNCT07864896Phase 3
- Opioid-Free Versus Opioid-Based Anesthesia in Thyroid SurgeryRecruitingNCT07864155Not applicable
- Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain ManagementNot yet recruitingNCT07856654Phase 4
- Intravenous Paracetamol Versus Magnesium Sulfate for Control of Shivering Following Spinal Anesthesia in Cesarean SectionNot yet recruitingNCT07855588Phase 4
- Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic SurgeriesNot yet recruitingNCT07855575Phase 4
- Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal AnesthesiaNot yet recruitingNCT07855536Phase 4
- Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous NephrolithotomyNot yet recruitingNCT07855068Phase 4
- Effect of Intravenous Versus Caudal Dexmedetomidine on Perfusion Index and Hemodynamic Responses in Children Undergoing Infraumbilical SurgeryNot yet recruitingNCT07852039Phase 4
- Intranasal Dexmedetomidine and Perioperative Myocardial Injury in Patients Having Percutaneous Coronary InterventionsNot yet recruitingNCT07847580Not applicable
- Safety and Efficacy of Dexamethasone Versus Dexmedetomidine as Adjuvants in PENG Block in Hip Surgeries for Postoperative Pain ManagementNot yet recruitingNCT07847047Phase 3
- Esmolol Versus Dexmedetomidine for Opioid-sparing in Laparoscopic Gynecological SurgeryRecruitingNCT07846722Not applicable
- Suzetrigine Versus Standard Analgesia After Skin Cancer SurgeryNot yet recruitingNCT07843134Phase 4
- Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis ReleaseRecruitingNCT07840183Phase 4
- Suzetrigine Post DIEPNot yet recruitingNCT07839715Phase 3
- Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia RepairNot yet recruitingNCT07837492Phase 4
- Brain Activity and Changes in Consciousness During General AnesthesiaNot yet recruitingNCT07836205Phase 4
- Suzetrigine Added to Multimodal Analgesia for Women Undergoing Minimally Invasive HysterectomyNot yet recruitingNCT07836010Phase 4
- A Clinical Study of HS-IT101 Injection in Patients With Advanced Non-Small Cell Lung Cancer(FASTIL-Lung02)RecruitingNCT07830342Phase 1
- Suzetrigine (Journavx) for Pain Management After Spine SurgeryNot yet recruitingNCT07829718Phase 4
- Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive CrisisNot yet recruitingNCT07826988Phase 4
- Demedetomidine and Remifentanil in Electroconvulsive Therapy (ECT)RecruitingNCT07824817Phase 4
- Post-Vasectomy Pain StudyRecruitingNCT07824258Phase 1
- Suzetrigine in Tonsillectomy for Opioid-sparing Pain ManagementNot yet recruitingNCT07821931Phase 4
- Post-op Analgesia of Nail Unit ProceduresNot yet recruitingNCT07820969Phase 4
- Dexmedetomidine Versus Lidocaine for Optic Nerve Sheath Diameter During Craniotomy IntubationNot yet recruitingNCT07820540Phase 4
- Endocannabinoids in RewardRecruitingNCT07815691Phase 2
- Intrathecal Dexmedetomidine and Postoperative Delirium in Elderly Hip Fracture SurgeryNot yet recruitingNCT07810556Phase 2/3
- Efficacy and Safety of Low-Dose IL-2 in Neuromyelitis Optica Spectrum DisorderNot yet recruitingNCT07809724Phase 2
- Impact of Dexmedetomidine Versus Propofol on Intracranial Pressure in Adult Traumatic Brain Injury Patients: Randomized Controlled Double-Blind TrialNot yet recruitingNCT07807579Phase 4
- This Study Aims to Determine Whether Lower Doses (4 µg) of Intrathecal Dexmedetomidine Can Provide Comparable Analgesic Benefits While Minimizing Adverse Hemodynamic Effects in Patients Encountered in Our Setup( Shifa International Hospital Islamabad).Enrolling by invitationNCT07807020Phase 1/2
- Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in ChildrenRecruitingNCT07799311Phase 4
- Suzetrigine vs. Standard Care Pain Relief Following Outpatient Knee Replacement SurgeryNot yet recruitingNCT07796152Phase 4
- Suzetrigine for Postoperative Pain After Total Ankle ReplacementNot yet recruitingNCT07795827Phase 4
- A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Verducatib in the BloodRecruitingNCT07781631Phase 1
- Intravenous Infusion of Low Dose Ketamine Versus Dexmedetomedine for Delirium Treatment in Acute Heart FailureNot yet recruitingNCT07781462Phase 4
- High- vs Standard-Dose Intravenous Magnesium for Acute HeadacheRecruitingNCT07779486Not applicable
- Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation SurgeriesRecruitingNCT07777627Not applicable
- Effect of Nebulized Dexmedetomidine on Central Sensitization and Chronification in MigraineRecruitingNCT07769255Not applicable
- Intranasal Dexmedetomidine vs. Oral Chloral Hydrate for Pediatric Orthopedic Procedural SedationNot yet recruitingNCT07768566Not applicable
- Effect of Dexmedetomidine Combined With FNB/ACB on Sleep Quality After Knee SurgeryRecruitingNCT07767383Phase 4
- Fast-Track Anesthesia in Minimally Invasive Cardiac Surgery: Dexmedetomidine and Erector Spinae Plane Block vs Opioid-Based AnesthesiaNot yet recruitingNCT07749274Not applicable
- Intravenous Dexmedetomidine as a Perioperative Autonomic-Immune NeuromodulatorNot yet recruitingNCT07743853Not applicable
- A Study on the Preventive Effect of Electroacupuncture Combined With Dexmedetomidine in Post-stroke DepressionNot yet recruitingNCT07739329Phase 4
- Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.Not yet recruitingNCT07736352Not applicable
- Acetaminophen vs Placebo for Postoperative Analgesia After Abdominal SurgeryNot yet recruitingNCT07720791Phase 4
- Pilot Studies Blocking Injury-Induced MVP Release in Skin Using Topical AmitriptylineNot yet recruitingNCT07716722Phase 1
- Quadro-Iliac Plane Block for Pain Control After Posterior Spinal Instrumentation SurgeryNot yet recruitingNCT07711522Early Phase 1
- A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become PregnantRecruitingNCT07710729Phase 1
- Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI StudyEnrolling by invitationNCT07705022Phase 2
- The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline AnesthesiaNot yet recruitingNCT07699523Not applicable
- REmifentanil And Dexmedetomidine for EarlY Intensive Blood Pressure Lowering in ICH.Not yet recruitingNCT07695220Not applicable
- Efficacy of Non-opioid Drugs in Addition to Opioid Therapy for Cancer Pain ManagementNot yet recruitingNCT07682558Phase 3
- Comparing Sedatives for Intracranial Pressure Control in Traumatic Brain InjuryNot yet recruitingNCT07678216Not applicable
- Preoperative Nebulized Dexmedetomidine Versus Nebulized Magnesium Sulphate in Reducing Emergence Agitation in FESSEnrolling by invitationNCT07677917Phase 1
- ACB and iPACK Blocks With Intravenous Dexamethasone and Perineural Dexmedetomidine in Total Knee ArthroplastyNot yet recruitingNCT07677215Not applicable
- Hemodynamic Effect of Dexmedetomidine Versus Magnesium Sulphate as an Adjuvant to Lidocaine in Preemptive Peribulbar Block in Patients Undergoing Dacryocystorhinostomy Under General AnesthesiaRecruitingNCT07675616Not applicable
- Precision Pain Management - A Randomized Clinical Trial Assessing the Efficacy of Suzetrigine on Postoperative Analgesia Among Surgical Patients at Higher Risk for Persistent Postoperative Opioid Use (POU)RecruitingNCT07672015Phase 4
- a Comparive Study of Ketamine-Propofol Versus Dexmedetomidine-Propofol Sedation in Pediatric Patients Undergoing Cardiac Catheterization for Device Closure of Simple Left-to-right ShuntsRecruitingNCT07669012Phase 1
- Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic ShockNot yet recruitingNCT07657715Not applicable
- Challenging the Endocannabinoid System in Sleep Restricted Healthy Volunteers to Modulate Physiological Arousal (CANISLEEP) StudyRecruitingNCT07656350Not applicable
- Assessing Suzetrigine for Pain Reduction Following Ureteroscopic SurgeryNot yet recruitingNCT07654296Phase 3
- Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's DiseaseRecruitingNCT07651319Phase 1/2
- The Effects of Different Anesthetics on the Brain's Neural NetworksNot yet recruitingNCT07644663Phase 4
- The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .RecruitingNCT07640516Not applicable
- Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle ReleaseNot yet recruitingNCT07640061Phase 1
- DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.RecruitingNCT07635563Phase 2
- Intravenous Metoclopramide Versus Intravenous Acetaminophen for Acute Concussion TreatmentNot yet recruitingNCT07634393Phase 4
- Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After Total Knee ArthroplastyNot yet recruitingNCT07624526Phase 4
- Opiranserin for Minimally Invasive CholecystectomyRecruitingNCT07620665Not applicable
- Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled TrialRecruitingNCT07611890Phase 4
- Low-dose Interleukin-2 After Myocardial Infarction to Investigate Effects on Tissue-resident Regulatory T CellsRecruitingNCT07610538Not applicable
- Intranasal Dexmedetomidine-esketamine on Sleep and Cognition in Older Adults With Mild-to-moderate Cognitive ImpairmentNot yet recruitingNCT07610343Phase 4
- The Effect of Different Intra-canal Medications on Postoperative PainRecruitingNCT07603934Early Phase 1
- The Pharmacokinetics of a Hemp-Based Topical ProductRecruitingNCT07603518Phase 1
- Dexmedetomidine vs Propofol-lidocaine Mixture in Preventing the Post Operative Emergence Agitation Following Sevoflurane AnasthesiaNot yet recruitingNCT07601698Phase 4
- Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive SurgeryNot yet recruitingNCT07600697Phase 4
- Comparing Pain Improvement for Intravenous Versus Oral Acetaminophen in Acute Pelvic PainNot yet recruitingNCT07595302Phase 4
- Dexmedetomidine Nasal Spray on Postoperative Delirium in Elderly Thoracoscopic Lung Resection PatientsNot yet recruitingNCT07579806Phase 4
- Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After SurgeryNot yet recruitingNCT07576543Phase 4
- Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After SurgeryNot yet recruitingNCT07576517Phase 4
- Impact of Preemptive Analgesia on Postoperative Pain in Orthognathic SurgeryRecruitingNCT07571252Phase 4
- A Study Of Synthetic THC And SleepNot yet recruitingNCT07570953Phase 2/3
- Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in ChildrenNot yet recruitingNCT07570160Phase 4
- Efficacy of the Alpha 2 Agonist Dexmedetomidine for Sympathetic Deactivation in REfractory Septic ShockNot yet recruitingNCT07569536Phase 3
- Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean DeliveryNot yet recruitingNCT07567495Phase 4
- Intranasal Dexmedetomidine vs Oral Midazolam for Premedication in Pediatric SurgeryRecruitingNCT07565116Not applicable
- Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft SurgeryRecruitingNCT07557576Not applicable
- Amitriptyline for IBS-like Symptoms in Quiescent Crohn's DiseaseRecruitingNCT07556718Phase 2
- Patient Quality of Recovery After TAVR With Different Sedation RegimensRecruitingNCT07556523Phase 4
- Dexmedetomidine and Propofol for Sedation in Cataract Surgery.RecruitingNCT07556133Not applicable
- Intranasal Dexmedetomidine for Acute Anxiety State in AdultsRecruitingNCT07550881Phase 2
- Intranasal Dexmedetomidine and Perioperative Myocardial InjuryNot yet recruitingNCT07549282Phase 4
- Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAINRecruitingNCT07548385Phase 3
- Impact on Delirium of the Use of DEXmedetomidine as First-line Sedation in PEDIAtric Intensive CareNot yet recruitingNCT07542990Phase 3
- Paracetamol and Ibuprofen With or Without Famotidine for Calcific Tendinitis of the ShoulderNot yet recruitingNCT07539961Not applicable