Analgesics, Non-Narcotic: all 3,330 studies that test it
Page 13 of 34. Open to participants first (511), then studies with results posted, then the rest; newest registration first within each.
- Effect of Anterior Disc Displacement With Reduction on Postoperative Pain After Root Canal TreatmentCompletedNCT07329413Not applicable
- Efficacy of Oral Paracetamol Compared With Oral Ketoprofen for Pain Management in Office HysteroscopyCompletedNCT07315698Phase 4
- LAPOFAR Trial: Opioid-Free vs. Remifentanil Anesthesia in Laparoscopic CholecystectomyCompletedNCT07307625Not applicable
- Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent PatientsWithdrawnNCT07306702Phase 4
- Preemptive Intravenous Micro-dose Dexmedetomidine to Prevent Emergence Agitation in Adult Patients Undergoing Septoplasty SurgeriesCompletedNCT07302815Not applicable
- Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic LaparotomyCompletedNCT07292324Phase 4
- To Assess the Enzyme Inducing Effects of Carbamazepine on the PK of Mirdametinib in Healthy ParticipantsCompletedNCT07279233Phase 1
- Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid SurgeryCompletedNCT07274670Not applicable
- Effect of Total Intravenous Anesthesia vs Inhalational Anesthesia on the Level of Inflammatory MarkersActive, not recruitingNCT07271459Not applicable
- A Study Of Opioid Avoidance In Surgery Through Integrating SuzetrigineCompletedNCT07257133Phase 4
- Comparison of Pain Using CPOT Score With Ketamine vs. Dexmedetomidine in Post-Craniotomy ICU PatientsCompletedNCT07254936Not applicable
- Comparison b/w Carbamazepine vs Oxcarbazepine in Treatment of Trigeminal NeuralgiaActive, not recruitingNCT07252453Not applicable
- A Randomized Comparison Between 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg of Perineural Dexmedetomidine for Ultrasound-Guided Infraclavicular BlockCompletedNCT07249827Phase 2
- Effectiveness of Dexmedetomidine Versus Sufentanil on Cerebral Oxygen Saturation in Patients With Traumatic Brain InjuryCompletedNCT07244822Not applicable
- Dexmedetomidine as an Adjunct to Fentanyl for Term Neonates on Mechanical VentilationCompletedNCT07241351Phase 2/3
- Hemodynamic Effects of Fentanyl Vs Dexmedetomidine in Spine SurgeryCompletedNCT07238101Phase 4
- A Clinical Study of Connective Tissue Graft and Enamel Matrix Derivative in the Treatment of Intrabony Periodontal DefectsCompletedNCT07233733Not applicable
- Sex Differences in Neurobehavioral Response to THCTerminatedNCT07225777Phase 2
- The Effectiveness of Intracuff Dexmedetomidine in Preventing Postoperative Sore Throat Following Prone SurgeryCompletedNCT07202624Phase 2
- A Study to Learn if Multiple Doses of the Study Medicine Called Carbamazepine Changes How the Body Processes the Other Study Medicine PF-07248144CompletedNCT07198035Phase 1
- Dexmedetomidine vs Ketamine as Adjuvants to Bupivacaine in Transversus Abdominus Plane Block in Inguinal HernioplastyCompletedNCT07194694Phase 3
- Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic ProceduresCompletedNCT07190612Phase 4
- Clinical Study to Evaluate the Effects of Oral Delta-9-tetrahydrocannabinol (Δ9-THC) With and Without Alcohol on Perception and Driving Performance in Healthy AdultsCompletedNCT07176208Phase 1
- Dexmedetomidine vs Propofol in High-Risk ERCP PatientsCompletedNCT07166614Not applicable
- Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in AdultsCompletedNCT07162649Not applicable
- Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU PatientsCompletedNCT07151716Phase 4
- Role of Pericapsular Nerve Block Using Dexmedetomidine and Bupivacaine in Improving the Outcome of Patients Undergoing Hip Surgery Under Spinal AnesthesiaCompletedNCT07149168Phase 1
- Dexmedetomidine Dose-Dependent on Lung Function and AQP1 in One-Lung Ventilation SurgeryCompletedNCT07145814Not applicable
- ED50 of Dexmedetomidine as an Adjuvant to 0.5% Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Hip and Knee Surgery: An Up-and-Down Method ApproachCompletedNCT07144215Not applicable
- COMPARISON OF BUPIVACAINE WITH AND WITHOUT DEXMEDETOMIDINE IN CAUDAL BLOCK AMONG CHILDREN UNDERGOING INGUINAL HERNIOTOMYCompletedNCT07140627Phase 1
- Intravenous Regional Analgesia of DexmedetomidineActive, not recruitingNCT07131579Not applicable
- Effect of Common Analgesia on Pulp SensibilityCompletedNCT07125911Not applicable
- Postoperative Pain Relief in Children: Comparing Caudal Bupivacaine Alone Versus Bupivacaine With Dexmedetomidine for Infra-Umbilical Surgeries Under General AnesthesiaCompletedNCT07121764Phase 4
- Assessment of Acute Psychomotor Agitation Measures Associated With Schizophrenia and Bipolar DisorderCompletedNCT07116694Phase 2
- A Study Comparing Propranolol and Amantadine for Reducing Tremors in People With Parkinson's DiseaseCompletedNCT07113015Not applicable
- Total Intravenous Anesthesia in Patients Undergoing CraniotomyActive, not recruitingNCT07105618Not applicable
- Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous TherapiesActive, not recruitingNCT07102641Phase 4
- A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Nerandomilast in the BloodCompletedNCT07100964Phase 1
- Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve BlocksActive, not recruitingNCT07099222Phase 1/2
- Acetaminophen Before Surgery Lowers Postop Pain in Pediatric Solid Tumor Patients (ERAS)CompletedNCT07095816Phase 1
- The Effects of Dexmedetomidine and Remifentanil on Kidney Injury After Muscle Compression Injury in RatsCompletedNCT07094165Not applicable
- Impact of Adding Dexmedetomidine as an Adjuvant to The Local Anesthetic in Quadratus Lumborum Block in Patient Undergoing Caesarean SectionCompletedNCT07072650Phase 1
- Intranasal Dexmedetomidine, Ketamine or Midazolam for Anxiety and Respiratory Complications in ChildrenCompletedNCT07072117Not applicable
- Pain Control After Open Radical Nephrectomy: Thoracic Paravertebral Block Versus External Oblique Intercostal BlockCompletedNCT07071012Not applicable
- Prophylactic IV Paracetamol in Extremely Premature InfantsCompletedNCT07067177Phase 2/3
- Adding Dexmedetomidine to Mannitol to Attenuate the Increase of Intracranial PressureCompletedNCT07064720Phase 2/3
- Dexmedetomidine as an Additive for (Ipack)Block in Knee SurgeryCompletedNCT07058493Not applicable
- Effect of Different Drugs on Emergency Delirium in Preschool Age PatientActive, not recruitingNCT07057193Not applicable
- Efficacy of Nebulized Dexmedetomidine on Blunting Hemodynamic Changes During Intubation and Pneumoperitoneum in Morbid Obese Patients During Laparoscopic Bariatric SurgeryCompletedNCT07054138Not applicable
- Effect of Different Doses Of Intrathecal Dexmedetomidine In Combination With Bupivacaine On Spinal AnesthesiaCompletedNCT07051512Phase 1
- Dexmedetomidine Versus Ketamine on Laryngeal MicrosurgeryCompletedNCT07048873Not applicable
- A Comparative Bioavailability Study of Reformulated Ibuprofen 2% and 4% Oral Suspensions (Berlin Chemie AG) and Versus Ibuprofen (Nurofen®) 200 mg/5 ml Oral SuspensionCompletedNCT07036861Phase 1
- Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Open Subcostal Renal SurgeriesCompletedNCT07012590Not applicable
- Comparison Paravertebral and Serratus Anterior Plane Block in Video-assisted Thoracoscopic Surgery.Active, not recruitingNCT07002788Not applicable
- Analgesic and Sedative Effect of Fentanyl Versus Dexmedetomidine Infusion in Post-Operative Mechanically Ventilated Children After Open Abdominal SurgeriesCompletedNCT06994273Not applicable
- Effect of Dexmedetomidine on Microsurgery Reconstruction in Cancer PatientCompletedNCT06993740Not applicable
- Effectiveness of Intranasal Dexmedetomidine Premedication in Child IntubationCompletedNCT06991647Phase 3
- Efficacy of Intraoperative Magnesium Sulphate vs Dexmedetomidine on Emergence Agitation in Pediatric PatientsCompletedNCT06977425Not applicable
- Infusion of Dexmedetomidine Versus Lidocaine in Management of Acute Postoperative Pain After Modified Radical MastectomyCompletedNCT06974656Not applicable
- Pharmacodynamic Study of 100mg Suzegtrigine vs Placebo in Healthy Male AdultsCompletedNCT06972212Early Phase 1
- The Efficacy of a Smart Phone-based Test on Measuring Pupillary Light Reflex Alterations Following Cannabis Use Healthy in AdultsCompletedNCT06967051Not applicable
- Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy AdultsTerminatedNCT06965881Phase 1
- Effect of Dexmedetomidine on Hemodynamics in Cardiac SurgeryCompletedNCT06958913Not applicable
- Effect of Dexmedetomidine on Acute Kidney Injury After Ascending Aortic SurgeriesActive, not recruitingNCT06958367Phase 1
- Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block vs Bupivacaine Alone for Hemodynamics Stability in CraniotomyCompletedNCT06951256Not applicable
- Dexmedetomidine Versus Ketamine-midazolam Sedation in Awake Fiberoptic Intubation in Suspected Difficult AirwayCompletedNCT06946212Phase 4
- Using Lidocaine or Dexmedetomidine to Help Control Blood Pressure Spikes From a Tourniquet During Knee SurgeryCompletedNCT06936410Phase 2
- Evaluation of the Analgesic Efficacy of the Combination of Dexketoprofen + Paracetamol and the Combination of Naproxen Sodium + Codeine in Patients With Acute Dental PainCompletedNCT06916234Phase 4
- Effect of Intraarticular Ozone, Prolotherapy or Dexmedetomidine in Pain Limitation in Knee OsteoarthritisCompletedNCT06909305Not applicable
- A Study to Evaluate the Effect of Food on the Single-Dose Pharmacokinetics and a Drug-Drug Interaction Evaluation of Itraconazole and Carbamazepine on INCB123667 When Administered Orally to Healthy Adult ParticipantsCompletedNCT06909162Phase 1
- Dexmedetomidine Enhancing the Recovery After Cardiac SurgeryCompletedNCT06907277Not applicable
- Effect of Dexmedetomidine and Total Intravenous Anesthesia on Endothelial Damage-Related BiomarkersCompletedNCT06897696Phase 4
- A Single-Arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Aesthetic or Reconstructive SurgeriesCompletedNCT06887972Phase 4
- A Single-arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Selected SurgeriesCompletedNCT06887959Phase 4
- Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled StudyCompletedNCT06884670Phase 2
- Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: The OPUS Anesthesia Pilot TrialActive, not recruitingNCT06884540Not applicable
- Comparison of Oral Dexmedetomidine, Ketamine Versus Midazolam for Premedication in Children Undergoing Injuinal SurgeriesCompletedNCT06879496Not applicable
- Dexmedetomidine Versus Magnesium Sulfate as Adjuvants to Intraperitoneal Bupivacaine for Postoperative Analgesia After Elective Laparoscopic CholecystectomyCompletedNCT06879288Not applicable
- Dexmedetomidine Infusion in Either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus SurgeryCompletedNCT06866145Phase 4
- Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute ExacerbationCompletedNCT06863636Phase 3
- Dexmedetomidine vs Tramadol for Anxiety, Pain, and Hemodynamics in HemorrhoidectomyCompletedNCT06860100Not applicable
- Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Functional Endoscopic Sinus SurgeryCompletedNCT06848764Not applicable
- A Drug-Drug Interaction Study to Evaluate the Effects of Itraconazole, Carbamazepine, Quinidine and Fluconazole on the Pharmacokinetics and Safety of EDP-323.CompletedNCT06847464Phase 1
- Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic SurgeryCompletedNCT06837519Not applicable
- Sevoflurane and Dexmedetomidine's Contrasting Renal Impacts After Non-Cardiac SurgeryCompletedNCT06835010Not applicable
- Dronabinol As an Adjunct for Reducing Pain (DARP)-Texas Children's HospitalWithdrawnNCT06834997Phase 2
- A Study of Suzetrigine (SUZ) Spray-dried Dispersion (SSD) in Healthy Adult PanelistsCompletedNCT06834009Phase 1
- Adding Amantadine to Pregabalin on Occurrence of Post-thoracotomy Pain SyndromeCompletedNCT06833203Not applicable
- Evaluation of the Effect of Suzetrigine (SUZ) on the Pharmacokinetics of Oral Contraceptives in Healthy Female ParticipantsCompletedNCT06820307Phase 1
- Effect of Pilates Exercises and TENS Acupuncture in Primary Dysmenorrhea Among Female Students At KAUCompletedNCT06808529Early Phase 1
- Postoperative Cognitive Dysfunction in Transsphenoidal Pituitary SurgeriesCompletedNCT06793150Phase 4
- Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis SurgeryCompletedNCT06789016Phase 4
- Comparative Study of Fentanyl vs Dexmedetomidine as Adjuvants to Intrathecal Bupivacaine in Cesarean SectionCompletedNCT06785285Not applicable
- Variability of Sulfotransferase Activity in Humans: an Approach to Improve Predictive Drug Response Part II: Analysis of Interindividual Variation in Hypertensive PatientsCompletedNCT06782204Phase 1
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-4729 Injection in Healthy SubjectsCompletedNCT06762600Phase 1
- DISE in Pediatric Sleep Disordered BreathingWithdrawnNCT06756971Phase 2/3
- A Drug-drug Interaction Study of S-892216 Coadministered With Carbamazepime to Healthy Adult ParticipantsCompletedNCT06751017Phase 1
- Adding Magnesium Sulfate or Dexmedetomidine to Bupivacaine in Oblique Subcostal Tap Block for Laparoscopic Cholecystectomy: A Randomized Double -Blind Controlled StudyCompletedNCT06743919Phase 4
- Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.CompletedNCT06741566Early Phase 1
- Serratus Anterior Plane Block Versus Erector Spinae Plane Block With Dexmedetomidine Added to Bupivacaine for Ultrasound-Guided Pain Management After MastectomyCompletedNCT06737458Not applicable