Drug
Miltefosine clinical trials
Also written Impavido.
- studies test it
- 35
- open now
- 4
- in phase 3
- 14
- first study started
- 2004
Keep track of what changes. Save the miltefosine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
33 studies that test it; most in 2007 (5); 1 more planned to start later
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2005 | 3 |
| 2006 | 2 |
| 2007 | 5 |
| 2008 | 3 |
| 2009 | 1 |
| 2010 | 3 |
| 2011 | 1 |
| 2014 | 2 |
| 2015 | 2 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2019 | 1 |
| 2021 | 1 |
| 2022 | 2 |
| 2023 | 1 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 4
- Phase 2
- 20
- Phase 3
- 14
- Phase 4
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 34
Drugs for Neglected Diseases (8) · AB Foundation (5) · Banaras Hindu University (3) · University of Brasilia (2) · International Centre for Diarrhoeal Disease Research, Bangladesh (2) · Fundacion Nacional de Dermatologia (2) · Centro Internacional de Entrenamiento e Investigaciones Médicas (2) · Foundation Fader (2)
Often tested with
Tested in the same studies.
Liposomal amphotericin B (7) · Amphotericin B (7) · Paromomycin (5) · Meglumine Antimoniate (2) · Thermotherapy (1) · Ivermectin (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Imiquimod (1)
Studies
Open first, then newest update. How each study uses miltefosine is read from its arms, and is right about nine times in ten.
Testing it · 35
- Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL)Not yet recruitingPhase 3Institute of Tropical Medicine, BelgiumNCT07463040Written as Miltefosine
- Pilot Study: Miltefosine Gel (G-MTF) in Patients With Cutaneous LeishmaniasisNot yet recruitingPhase 1Universidad Industrial de SantanderNCT07149753Written as MILTEFOSINE gel
- Treatment of Bolivian L Braziliensis Mucosal Leishmaniasis With Inhaled Pentamidine Plus Oral MiltefosineRecruitingPhase 2Fundacion Nacional de DermatologiaNCT06550609Written as Miltefosine Oral Capsule
- Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the ElderlyRecruitingPhase 2/3University of BrasiliaNCT06040489Written as Miltefosine 50mg
- Randomised Clinical Trial in Treatment Modalities for Cutaneous Leishmaniasis Caused by Leishmania Tropica, in PakistanCompletedPhase 3Medecins Sans Frontieres, NetherlandsNCT04268524Written as drug: miltefosine with thermotherapy
- Repurposing Ivermectin for PKDL TreatmentCompletedEarly Phase 1International Centre for Diarrhoeal Disease Research, BangladeshNCT06251739Written as Miltefosine Oral Capsule
- Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New WorldCompletedPhase 3Drugs for Neglected DiseasesNCT04515186Written as Miltefosine
- Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern AfricaCompletedPhase 3Drugs for Neglected DiseasesNCT03129646Written as Miltefosine
- The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in BrazilActive, not recruitingPhase 2University of BrasiliaNCT02530697Written as Miltefosine
- Oral Miltefosine Plus Topical Paromomycin In American Cutaneous LeishmaniasisCompletedPhase 2/3Fundacion Nacional de DermatologiaNCT03829917Written as Miltefosine and Paromomycin
- Miltefosine to Treat Mucocutaneous LeishmaniasisCompletedPhase 2Knight Therapeutics (USA) IncNCT01050907Written as Miltefosine
- Miltefosine and GM-CSF in Cutaneous LeishmaniasisCompletedPhase 3Hospital Universitário Professor Edgard SantosNCT03023111Written as Miltefosine plus GM-CSF
- Thermotherapy + a Short Course of Miltefosine for the Treatment of Uncomplicated Cutaneous Leishmaniasis in the New World¨CompletedPhase 2Drugs for Neglected DiseasesNCT02687971Written as Miltefosine
- Miltefosine for Children With PKDLCompletedPhase 3International Centre for Diarrhoeal Disease Research, BangladeshNCT02193022Written as Miltefosine
- Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.CompletedPhase 3Drugs for Neglected DiseasesNCT02011958Written as Miltefosine
- Efficacy and Safety of Miltefosine or Thermotherapy for Cutaneous Leishmaniasis in Colombia.CompletedPhase 3Universidad de AntioquiaNCT00471705Written as Miltefosine
- Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern AfricaCompletedPhase 2Drugs for Neglected DiseasesNCT01067443Written as Liposomal amphotericin B + miltefosine
- Efficacy and Safety of Miltefosine in Antihistamine Resistant Chronic UrticariaTerminatedPhase 2Marcus MaurerNCT01170949Written as Miltefosine
- Pharmacokinetics/Safety of Miltefosine Allometric Dose for the Treatment of Visceral Leishmaniasis in Children in Eastern AfricaCompletedPhase 2Drugs for Neglected DiseasesNCT02431143Written as Miltefosine
- Pharmacokinetics of Miltefosine in Children and AdultsCompletedPhase 4Centro Internacional de Entrenamiento e Investigaciones MédicasNCT01462500Written as Miltefosine
See all 35 studies that test miltefosine →
Given in every arm · 1 — miltefosine is usual care beside what is tested
As the comparator · 2 — what is tested is compared with miltefosine
- A Clinical Trial to Investigate Efficacy, Safety and Pharmacokinetics (PK) of Two LXE408 Oral Regimens and Oral Miltefosine as Active Control in Participants Aged ≥ 18 Years Old With Localized Cutaneous Leishmaniasis in the Region of the Americas (AMR).Not yet recruitingPhase 2Drugs for Neglected DiseasesNCT06997159Written as Miltefosine 50 MG Oral Capsule [Impavido]
- Treatment of Mucosal Bolivian LeishmaniasisRecruitingPhase 3Fundacion Nacional de DermatologiaNCT04799236Written as Group 1: Miltefosine
Codes
What other systems call miltefosine · ClinicalTrials.gg INT003115
- MeSH (NLM) C039128miltefosineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 53EY29W7ECMILTEFOSINEConfirmed FDA, NLM, Wikidata
- RxNorm 1494066Confirmed FDA, Wikidata
- Wikidata Q411787miltefosineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1170MiltefosineOne source FDA
- DrugBank DB09031One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C039128 | miltefosine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 53EY29W7EC | MILTEFOSINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1494066 | — | Confirmed FDA, Wikidata |
| Wikidata | Q411787 | miltefosine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1170 | Miltefosine | One source FDA |
| DrugBank | DB09031 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.