Leishmaniasis, Visceral clinical trials
The registry lists 68 studies for Leishmaniasis, Visceral across more than 10 countries. 7 are recruiting or about to start. 62 of them are mainly about Leishmaniasis, Visceral (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29.
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Who runs them
Drugs for Neglected Diseases (13) · Banaras Hindu University (8) · International Centre for Diarrhoeal Disease Research, Bangladesh (7) · Institute of Tropical Medicine, Belgium (6) · Foundation for Innovative New Diagnostics, Switzerland (4) · Access to Advanced Health Institute (AAHI) (3) · PATH (3) · University of Brasilia (2)
What is being tested here
Drugs under test in Leishmaniasis, Visceral studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With Leishmaniasis · Institute of Tropical Medicine, Belgium
- Dec 2026Clinical Prognostic Score to Predict Relapse in VL · Institute of Tropical Medicine, Belgium
- Apr 2027Recurrent Visceral Leishmaniasis in HIV Co-Infection · Institute of Tropical Medicine, Belgium
Who these studies take
Of the 7 Leishmaniasis, Visceral studies recruiting now, 2 (29%) set no upper age limit and 3 (43%) stop at 75 or younger. 4 (57%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (43%) | 3 (43%) |
| 18 | 6 (86%) | 6 (86%) |
| 30 | 6 (86%) | 6 (86%) |
| 40 | 6 (86%) | 6 (86%) |
| 50 | 6 (86%) | 6 (86%) |
| 65 | 6 (86%) | 6 (86%) |
| 75 | 5 (71%) | 5 (71%) |
| 85 | 4 (57%) | 4 (57%) |
Across all 68 studies, recruiting or not: 66% stop at 75 or younger and 63% at 65; 72% take children; 0% are for women only and 0% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 68. Browse all 68 → or search them.
- Diagnosis and Treatment of Leishmania InfectionsRecruitingNCT003441881 country
- Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With LeishmaniasisRecruitingNCT077832431 country
- LEISH-PED: Study on Leishmaniasis in ChildrenRecruitingNCT075047571 country
- Recurrent Visceral Leishmaniasis in HIV Co-InfectionRecruitingNCT074873501 country
- Visceral Leishmaniasis in Emilia-Romagna (Leishmania-2019)RecruitingNCT067931111 country
- Clinical Prognostic Score to Predict Relapse in VLRecruitingNCT056026101 country
- Real World Study of Classic Infectious DiseaseRecruitingNCT040205361 country
- Evaluation of Less Invasive Procedures for Visceral Leishmaniasis Treatment Efficacy Monitoring Test of CureCompletedNCT054265771 country
- A First-in-human, Safety, Tolerability, and Pharmacokinetics Study of LXE408 in Healthy SubjectsCompletedNCT07809919Phase 11 country
- Human Bioequivalence Study of Liposomal Amphotericin B for InjectionCompletedNCT06983665Not applicable1 country
- Human Bioequivalence Study of Amphotericin B Liposome for InjectionCompletedNCT06977490Not applicable1 country
- A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral LeishmaniasisCompletedNCT05593666Phase 21 country
- Ivermectin Repurposed for the Treatment of PKDLCompletedNCT07286604Early Phase 11 country
- LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept StudyCompletedNCT05957978Phase 21 country
- Repurposing Ivermectin for PKDL TreatmentCompletedNCT06251739Early Phase 11 country
- A Study to Assess Immune Response Status in Patients Before and After Treatment for Visceral LeishmaniasisActive, not recruitingNCT043427151 country
- Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South SudanCompletedNCT054497171 country
- Leishmania Antigen Rapid Diagnostic Test Proof-of-Concept and Validation StudyTerminatedNCT061187491 country
- Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern AfricaCompletedNCT03129646Phase 34 countries
- LAMP Assay for the Diagnosis of Visceral LeishmaniasisCompletedNCT040035321 country
- Evaluation to Assess the Usability of rK28 for the Diagnosis of Visceral Leishmaniasis in KenyaStatus unknownNCT053868751 country
- Single Oral Dose Escalation Study of DNDI-0690 in Healthy SubjectsCompletedNCT03929016Phase 11 country
- A Study to Assess Safety and Efficacy of a Leishmania Vaccine to Prevent Post Kala Azar Dermal Leishmaniasis (PKDL)WithdrawnNCT04107961Phase 2
- Predicting Visceral Leishmaniasis in HIV Infected PatientsTerminatedNCT030136731 country
- Evaluation of Antibody Detection Tests for Visceral Leishmaniasis Diagnosis in Eastern AfricaCompletedNCT036469812 countries
- Short Course Regimens for Treatment of PKDL (Sudan)Status unknownNCT03399955Phase 21 country
- Improved Case Detection and Vector Control for Visceral LeishmaniasisCompletedNCT03269006Not applicable1 country
- Steady State Global Bioequivalence Study of Amphotericin B Liposome for Injection 50 mg/ Vial in Fed ConditionCompletedNCT03636659Phase 12 countries
- Miltefosine for Children With PKDLCompletedNCT02193022Phase 31 country
- Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.CompletedNCT02011958Phase 31 country
- Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort StudyCompletedNCT01360762Phase 31 country
- Asymptomatic Leishmania Infection in HIV PatientsTerminatedNCT028396031 country
- A Pilot Study for Capacity Building for a Multi-centre, Randomized Trial for Treatment of Kala Azar in BangladeshCompletedNCT01240473Not applicable1 country
- Safety and Effectiveness of Short-course AmBisome in the Treatment of PKDL in BangladeshCompletedNCT03311607Phase 4
- A Study Evaluating Sitamaquine Compared With Amphotericin B In The Treatment Of Visceral Leishmaniasis.CompletedNCT00381394Phase 21 country
- Amphotericin B to Treat Visceral Leishmaniasis in Brazilian ChildrenCompletedNCT01032187Phase 41 country
- Efficacy and Safety Study of Drugs for Treatment of Visceral Leishmaniasis in BrazilTerminatedNCT01310738Phase 41 country
- Replacement of Insecticides to Control Visceral Leishmaniasis (VL)CompletedNCT01644682Phase 31 country
- Immunogenetics of Visceral LeishmaniasisCompletedNCT003428231 country
- Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern AfricaCompletedNCT01067443Phase 22 countries
- Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)CompletedNCT01766830Not applicable4 countries
- Pharmacokinetics/Safety of Miltefosine Allometric Dose for the Treatment of Visceral Leishmaniasis in Children in Eastern AfricaCompletedNCT02431143Phase 22 countries
- Miltefosine for Brazilian Visceral LeishmaniasisTerminatedNCT00378495Phase 1/21 country
- Efficacy/Safety of Sodium Stibogluconate (SSG) Versus Paromomycin (PM) and SSG/PM Combination to Treat V LeishmaniasisCompletedNCT00255567Phase 34 countries
- Phase 1 LEISH-F3 + SLA-SE Vaccine Trial in Healthy Adult VolunteersCompletedNCT02071758Phase 11 country
- Phase III, Study of Three Short Course Combo (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome for the Treatment of VL in BangladeshCompletedNCT01122771Phase 31 country
- Open-Label, Sequential Step, Safety and Efficacy Study to Determine the Optimal Single Dose of Ambisome for Patients With VLTerminatedNCT00832208Phase 22 countries
- Trial to Determine Efficacy of Fexinidazole in Visceral Leihmaniasis Patients in SudanTerminatedNCT01980199Phase 21 country
- Open-Label Safety Study of Three-Antigen Leishmania Polyprotein With Adjuvant MPL-SE in Healthy Adults in IndiaCompletedNCT00486382Phase 11 country
- Expand Access/Assess Safety and Efficacy of Paromomycin IM Injection for the Treatment of Visceral LeishmaniasisCompletedNCT00604955Phase 41 country