Leishmaniasis clinical trials
The registry lists 77 studies for Leishmaniasis across more than 10 countries. 10 are recruiting or about to start. 29 of them are mainly about Leishmaniasis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29. Counting its 3 narrower conditions too, such as Leishmaniasis, Cutaneous: 209 studies, 27 open.
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Who runs them
U.S. Army Medical Research and Development Command (9) · Access to Advanced Health Institute (AAHI) (8) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · Knight Therapeutics (USA) Inc (5) · Institute of Tropical Medicine, Belgium (5) · Universidad de Antioquia (4) · Fundacion Nacional de Dermatologia (3) · AB Foundation (3)
What is being tested here
Drugs under test in Leishmaniasis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Human Leishmaniasis: Antigen Recognition Pattern and Study of New Potential Biomarkers · IRCCS Sacro Cuore Don Calabria di Negrar
- Dec 2026Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With Leishmaniasis · Institute of Tropical Medicine, Belgium
- Dec 2026Clinical Prognostic Score to Predict Relapse in VL · Institute of Tropical Medicine, Belgium
- Nov 2027Treatment of Bolivian L Braziliensis Mucosal Leishmaniasis With Inhaled Pentamidine Plus Oral Miltefosine · Fundacion Nacional de Dermatologia
Who these studies take
Of the 9 Leishmaniasis studies recruiting now, 5 (56%) set no upper age limit and 2 (22%) stop at 75 or younger. 6 (67%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (33%) | 3 (33%) |
| 18 | 8 (89%) | 8 (89%) |
| 30 | 8 (89%) | 8 (89%) |
| 40 | 8 (89%) | 8 (89%) |
| 50 | 9 (100%) | 9 (100%) |
| 65 | 9 (100%) | 9 (100%) |
| 75 | 8 (89%) | 8 (89%) |
| 85 | 7 (78%) | 7 (78%) |
Across all 77 studies, recruiting or not: 49% stop at 75 or younger and 39% at 65; 43% take children; 1% are for women only and 5% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 77. Browse all 77 → or search them.
- Diagnosis and Treatment of Leishmania InfectionsRecruitingNCT003441881 country
- Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With LeishmaniasisRecruitingNCT077832431 country
- Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis II.RecruitingNCT06822478Phase 31 country
- Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health PerspectiveRecruitingNCT073589101 country
- Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne DiseasesNot yet recruitingNCT06859619Not applicable1 country
- Treatment of Bolivian L Braziliensis Mucosal Leishmaniasis With Inhaled Pentamidine Plus Oral MiltefosineRecruitingNCT06550609Phase 21 country
- Visceral Leishmaniasis in Emilia-Romagna (Leishmania-2019)RecruitingNCT067931111 country
- Human Leishmaniasis: Antigen Recognition Pattern and Study of New Potential BiomarkersRecruitingNCT06307171Not applicable1 country
- Clinical Prognostic Score to Predict Relapse in VLRecruitingNCT056026101 country
- Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the ElderlyRecruitingNCT06040489Phase 2/31 country
- Evaluation of Less Invasive Procedures for Visceral Leishmaniasis Treatment Efficacy Monitoring Test of CureCompletedNCT054265771 country
- Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy ParticipantsTerminatedNCT04504435Phase 11 country
- Evaluation of CL Detect™ Rapid Test to Detect Cutaneous LeishmaniasisCompletedNCT018650321 country
- Ivermectin Repurposed for the Treatment of PKDLCompletedNCT07286604Early Phase 11 country
- Repurposing Ivermectin for PKDL TreatmentCompletedNCT06251739Early Phase 11 country
- Treatment of Leishmaniasis With Impavido® (Miltefosine): Pregnancy RegistryWithdrawnNCT024273081 country
- Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South SudanCompletedNCT054497171 country
- Mediterranean Visceral Leishmaniasis With Leishmania InfantumActive, not recruitingNCT037842481 country
- Arnica Tincture Fot the Treatment of Cutaneous LeishmaniasisActive, not recruitingNCT05094908Phase 11 country
- Spatial Analysis of Host-parasite Interactions in Cutaneous Leishmaniasis in EthiopiaCompletedNCT053320931 country
- Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy AdultsTerminatedNCT06124144Phase 11 country
- The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in BrazilActive, not recruitingNCT02530697Phase 21 country
- A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand FliesCompletedNCT04512742Not applicable1 country
- Cutaneous Leishmaniasis Diagnostic StudyCompletedNCT038374311 country
- Safety, Tolerability and Pharmacokinetics (PKs) Investigation of GSK3186899 in Healthy SubjectsTerminatedNCT03874234Phase 11 country
- A Study to Assess Safety and Efficacy of a Leishmania Vaccine to Prevent Post Kala Azar Dermal Leishmaniasis (PKDL)WithdrawnNCT04107961Phase 2
- Predicting Visceral Leishmaniasis in HIV Infected PatientsTerminatedNCT030136731 country
- Evaluation of the Safety and Clinical Activity of Curaleish in the Topical Treatment of Cutaneous Leishmaniasis.WithdrawnNCT04072874Phase 1/21 country
- Topical Liposomal Amphotericin B Gel Treatment for Cutaneous LeishmaniasisCompletedNCT02656797Phase 21 country
- Defining Skin Immunity of a Bite of Key Insect Vectors in HumansCompletedNCT03641339Not applicable1 country
- Sodium Stibogluconate Treatment of LeishmaniasisCompletedNCT00662012Phase 21 country
- Intralesional Antimony for Bolivian Cutaneous LeishmaniasisCompletedNCT01300975Phase 21 country
- Topical Paromomycin for Cutaneous Leishmaniasis in BoliviaCompletedNCT03096457Phase 2/31 country
- Miltefosine to Treat Mucocutaneous LeishmaniasisCompletedNCT01050907Phase 21 country
- Dedicated QT Study in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous LeishmaniasisCompletedNCT024295181 country
- Treatment of Leishmaniasis With Impavido® (Miltefosine): Higher-Weight Patient RegistryWithdrawnNCT024295051 country
- Th1/Th2 Polarization and Linkage to L. Viannia Infection OutcomesCompletedNCT004012971 country
- Expression of Mif Alleles in Individuals With LeishmaniasisCompletedNCT004013491 country
- Mechanisms Relating to the Distinct in Vitro Susceptibility of Human Macrophages to L. Viannia InfectionCompletedNCT004015571 country
- Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART CentreCompletedNCT039930931 country
- Use of Sodium Stibogluconate as a Treatment for LeishmaniasisCompletedNCT00657618Phase 1/21 country
- Safety, Efficacy, and PK of Topical Paromomycin/Gentamicin Cream for Treatment of Cutaneous LeishmaniasisTerminatedNCT01140191Phase 21 country
- Spermiogram Assessment in Bolivian Patients Taking Impavido® (Miltefosine) for Mucocutaneous LeishmaniasisCompletedNCT024314291 country
- Topical Treatment of Recalcitrant Ulcerative Old World Leishmaniasis With WR 279,396TerminatedNCT00657917Phase 21 country
- Efficacy and Safety of Miltefosine or Thermotherapy for Cutaneous Leishmaniasis in Colombia.CompletedNCT00471705Phase 31 country
- Immune Responses After Human Subject Challenge With Sand Fly BitesCompletedNCT012899771 country
- Phase 3 Study of Walter Reed (WR) 279,396 and Paromomycin Alone for the Treatment of Cutaneous Leishmaniasis in PanamaCompletedNCT01790659Phase 31 country
- Fourth-generation Immucillin Derivative DI4G Associated Therapy in Cutaneous LeishmaniasisCompletedNCT03294161Phase 21 country
- Evaluation of a Rapid Diagnostic Device, CL Detect, for the Diagnosis of Cutaneous Leishmaniasis in TunisiaCompletedNCT017696121 country
- Fractional CO2 Laser With Topical Pentostam Treatment for Cutaneous Leishmaniasis.Status unknownNCT03009422Not applicable