Leishmaniasis, Cutaneous clinical trials
The registry lists 103 studies for Leishmaniasis, Cutaneous across more than 10 countries. 18 are recruiting or about to start. 94 of them are mainly about Leishmaniasis, Cutaneous (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29. Counting its narrower condition Leishmaniasis, Mucocutaneous too: 114 studies, 20 open.
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Who runs them
U.S. Army Medical Research and Development Command (12) · Institute of Tropical Medicine, Belgium (9) · Hospital Universitário Professor Edgard Santos (9) · Drugs for Neglected Diseases (6) · Access to Advanced Health Institute (AAHI) (4) · Centro Internacional de Entrenamiento e Investigaciones Médicas (4) · Universidad de Antioquia (4) · University of York (4)
What is being tested here
Drugs under test in Leishmaniasis, Cutaneous studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- Mar 2027Antimicrobial Adjuvants to Revert the Imbalance of Skin Microbiota for Improved Outcomes of Complicated Cutaneous Leishmaniasis Treatment in Ethiopia · Phase 3 · Institute of Tropical Medicine, Belgium
- Dec 2026Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With Leishmaniasis · Institute of Tropical Medicine, Belgium
- Mar 2027Feasibility of Integrating Thermotherapy for Treatment of Cutaneous Leishmaniasis in Primary Health Care Setup · Armauer Hansen Research Institute, Ethiopia
Who these studies take
Of the 10 Leishmaniasis, Cutaneous studies recruiting now, 3 (30%) set no upper age limit and 3 (30%) stop at 75 or younger. 6 (60%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (30%) | 3 (30%) |
| 18 | 9 (90%) | 9 (90%) |
| 30 | 9 (90%) | 9 (90%) |
| 40 | 9 (90%) | 9 (90%) |
| 50 | 9 (90%) | 9 (90%) |
| 65 | 8 (80%) | 8 (80%) |
| 75 | 7 (70%) | 7 (70%) |
| 85 | 4 (40%) | 4 (40%) |
Across all 103 studies, recruiting or not: 50% stop at 75 or younger and 44% at 65; 57% take children; 0% are for women only and 2% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 103. Browse all 103 → or search them.
- Diagnosis and Treatment of Leishmania InfectionsRecruitingNCT003441881 country
- Feasibility of Integrating Thermotherapy for Treatment of Cutaneous Leishmaniasis in Primary Health Care SetupRecruitingNCT06746350Not applicable1 country
- Immersive Technology Headsets to Reduce Procedural Pain and Anxiety: Feasibility and Effects in Cutaneous Leishmaniasis Patients in PakistanNot yet recruitingNCT07858357Not applicable
- Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With LeishmaniasisRecruitingNCT077832431 country
- A Clinical Trial to Investigate Efficacy, Safety and Pharmacokinetics (PK) of Two LXE408 Oral Regimens and Oral Miltefosine as Active Control in Participants Aged ≥ 18 Years Old With Localized Cutaneous Leishmaniasis in the Region of the Americas (AMR).Not yet recruitingNCT06997159Phase 22 countries
- Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health WorkersNot yet recruitingNCT07506967Not applicable5 countries
- Arnica Tincture Fot the Treatment of Cutaneous Leishmaniasis II.RecruitingNCT06822478Phase 31 country
- LEISH-PED: Study on Leishmaniasis in ChildrenRecruitingNCT075047571 country
- Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL)Not yet recruitingNCT07463040Phase 31 country
- Intralesional Injection of Levofloxacin for the Management of Cutaneous LeishmaniasisRecruitingNCT06797544Phase 21 country
- Ciprofloxacin Intralesional Injection for the Treatment of Cutaneous Leishmaniasis Compared to Sodium StibogluconateRecruitingNCT06798402Phase 21 country
- Pilot Study: Miltefosine Gel (G-MTF) in Patients With Cutaneous LeishmaniasisNot yet recruitingNCT07149753Phase 11 country
- Intralesional Injection of Metronidazole for the Management of Cutaneous LeishmaniasisRecruitingNCT06798415Phase 21 country
- Antimicrobial Adjuvants to Revert the Imbalance of Skin Microbiota for Improved Outcomes of Complicated Cutaneous Leishmaniasis Treatment in EthiopiaNot yet recruitingNCT06695143Phase 31 country
- OPTImizing MIltefosine Treatment for Cutaneous LEISHmaniasis PatientsRecruitingNCT065145601 country
- Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous LeishmaniasisRecruitingNCT05708625Phase 31 country
- Tofacitinib Associated With Meglumine Antimoniate in Cutaneous LeishmaniasisNot yet recruitingNCT06011343Phase 2/31 country
- Pilot Study Using a Heat Pack to Treat Cutaneous LeishmaniasisAvailableNCT01277796
- Randomised Clinical Trial in Treatment Modalities for Cutaneous Leishmaniasis Caused by Leishmania Tropica, in PakistanCompletedNCT04268524Phase 31 country
- Complex Cutaneous Leishmaniasis Healing Study in AlgeriaTerminatedNCT032928351 country
- Combination, Miltefosine Monotherapy for Cutaneous Leishmaniasis in New WorldCompletedNCT04515186Phase 34 countries
- Enhancing Protection Against Vector-borne Diseases in Forcibly Displaced Communities: Evaluating the Efficacy of Spatial Repellents for Cutaneous Leishmaniasis Control in North-East SyriaCompletedNCT06917040Phase 31 country
- Arnica Tincture Fot the Treatment of Cutaneous LeishmaniasisActive, not recruitingNCT05094908Phase 11 country
- Spatial Analysis of Host-parasite Interactions in Cutaneous Leishmaniasis in EthiopiaCompletedNCT053320931 country
- Epidemiology of Cutaneous Leishmaniasis in Niger, Mali, Togo : Mapping of Clinical Cases, Species, Reservoirs and Vectors of the DiseaseCompletedNCT066929853 countries
- Treatment of Cutaneous Leishmaniasis With Liposomal Amphotericin B in the ElderlyCompletedNCT06449040Phase 1/21 country
- Documentation of Patient Outcomes for SSG/Allopurinol Combination Treatment in EthiopiaCompletedNCT046993831 country
- Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World LeishmaniasisNo longer availableNCT005089631 country
- A Clinical Study to Develop a Controlled Human Infection Model Using Leishmania Major-infected Sand FliesCompletedNCT04512742Not applicable1 country
- Topical Sm29 in Combination With Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis.CompletedNCT06000514Phase 1/21 country
- A Study to Assess the Safety, Efficacy and Immunogenicity of Leishmania Vaccine ChAd63-KH in PKDLCompletedNCT03969134Phase 21 country
- Cutaneous Leishmaniasis Diagnostic StudyCompletedNCT038374311 country
- Single Oral Dose Escalation Study of DNDI-0690 in Healthy SubjectsCompletedNCT03929016Phase 11 country
- A Clinical Study to Develop an Uninfected Sand Fly Biting ProtocolCompletedNCT03999970Not applicable1 country
- Study of Cases of Cutaneous Leishmaniasis Treated With Miltefosine in French Guiana, Retrospective StudyStatus unknownNCT05493059
- Evaluation of the Safety and Clinical Activity of Curaleish in the Topical Treatment of Cutaneous Leishmaniasis.WithdrawnNCT04072874Phase 1/21 country
- ASYMPTOMATIC CARRIER OF LEISHMANIA INFANTUM, MEDISERRANEAN VISCERAL LEISHMANIOSIS AGENT: STUDY OF IMMUNE RESPONSE -CompletedNCT03303898Not applicable1 country
- Investigation of an Outbreak Situation of Cutaneous Leishmaniasis Among Military Personnel in French Guiana (CEFELEISH)CompletedNCT048881301 country
- Development of Topical Herbal Formulations for Treatment of Cutaneous LeishmaniasisCompletedNCT04841239Not applicable1 country
- Diagnosis of Cutaneous Leishmaniasis Using the CL-detect Rapid Test in Travelers and Migrants in BelgiumTerminatedNCT040013351 country
- A Study to Evaluate the Efficacy and Tolerance of WR279,396 for Old World Cutaneous LeishmaniasisCompletedNCT01536795Phase 21 country
- Intralesional Antimony for Bolivian Cutaneous LeishmaniasisCompletedNCT01300975Phase 21 country
- Topical Paromomycin for Cutaneous Leishmaniasis in BoliviaCompletedNCT03096457Phase 2/31 country
- Miltefosine to Treat Mucocutaneous LeishmaniasisCompletedNCT01050907Phase 21 country
- Performance of RPA-LF for Cutaneous LeishmaniasisCompletedNCT045008731 country
- Outcomes of Complicated CL in Ethiopia Treated With MiltefosineCompletedNCT040047541 country
- Paromomycin for Individuals With Uncomplicated Cutaneous LeishmaniasisNo longer availableNCT016417961 country
- Efficacy of Intra-lesional Injections of Glucantime Once a Week or Twice a Week in the Treatment of Anthroponotic Cutaneous Leishmaniasis (ACL)CompletedNCT04340128Phase 31 country
- Miltefosine and GM-CSF in Cutaneous LeishmaniasisCompletedNCT03023111Phase 31 country
- A Study of a New Leishmania Vaccine Candidate ChAd63-KHCompletedNCT02894008Phase 21 country