Abacavir clinical trials
Also written Ziagen.
Counted the way a researcher would: Abacavir with its salts, dosage forms, brands and biosimilars. Looking for a trial to join? Including related medicines shows more you could take part in.
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How each study uses Abacavir is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- 17 Dec 1998 · ZIAGEN · NDA 020977 (FDA, Drugs@FDA)
- European Union
- 8 Jul 1999 · Ziagen · EMEA/H/C/000252 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
56 studies that test it; most in 1999 (9)
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1997 | 1 |
| 1999 | 9 |
| 2000 | 2 |
| 2001 | 2 |
| 2002 | 1 |
| 2003 | 1 |
| 2004 | 3 |
| 2005 | 5 |
| 2006 | 3 |
| 2007 | 5 |
| 2008 | 2 |
| 2009 | 2 |
| 2010 | 3 |
| 2011 | 1 |
| 2012 | 3 |
| 2013 | 3 |
| 2014 | 2 |
| 2015 | 1 |
| 2016 | 1 |
| 2022 | 2 |
| 2024 | 1 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 33 · Other 44
Glaxo Wellcome (17) · National Institute of Allergy and Infectious Diseases (NIAID) (14) · ViiV Healthcare (5) · GlaxoSmithKline (5) · Germans Trias i Pujol Hospital (3) · Kirby Institute (2) · Gilead Sciences (2) · Central Institute of Epidemiology, Moscow, Russia (1)
Often tested with
Tested in the same studies.
Lamivudine (32) · Efavirenz (15) · Zidovudine (13) · Ritonavir (11) · Amprenavir (11) · Dolutegravir (8) · Tenofovir (6) · Emtricitabine (5)
Related medicines
As reviewed, each with the page that says it.
Studies
Open first, then newest update. How each study uses Abacavir is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 77
- An Adaptive Platform Trial for Evaluation of Novel Treatment Regimens in Children and Adolescents With HIV in AfricaNot yet recruitingPhase 3University College, LondonNCT07792096Written as Abacavir (ABC)
- STARLITE for Unresectable High-Grade GliomasRecruitingPhase 1University of MiamiNCT06428045Written as Abacavir
- Efficacy and Tolerance of Abacavir/Lamivudine Treatment in Patients With Systemic Lupus ErythematosusNot yet recruitingPhase 2Hospices Civils de LyonNCT06356740Written as Treatment :Abacavir 600 mg/lamivudine 300 mg
- Triumeq in Amyotrophic Lateral SclerosisTerminatedPhase 3Macquarie University, AustraliaNCT05193994Written as Dolutegravir, Abacavir and Lamivudine
- Raltegravir + Lamivudine/Abacavir in HIV/Tuberculosis Co-Infected PatientsCompletedPhase 4Central Institute of Epidemiology, Moscow, RussiaNCT01059422Written as Raltegravir; Abacavir/Lamivudine
- Inhibition of Reverse Transcription in Aicardi-Goutières SyndromeCompletedPhase 2University of EdinburghNCT04731103Written as Abacavir (ABC)
- Triumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject DrugsTerminatedPhase 4University College DublinNCT02659761Written as dolutegravir/abacavir/lamivudine
- A Study to Determine Safety and Efficacy of Dolutegravir/Abacavir/Lamivudine (DTG/ABC/3TC) in Human Immunodeficiency Virus (HIV)-1 Infected Antiretroviral Therapy (ART) Naïve Women (ARIA)CompletedPhase 3ViiV HealthcareNCT01910402Written as Dolutegravir/abacavir/lamivudine FDC
- Safety and Efficacy of Fixed Dose Combination Dolutegravir/Abacavir/Lamivudine FDC Initiated During Acute HIV InfectionCompletedNot applicableUniversity of North Carolina, Chapel HillNCT02384395Written as Abacavir 600 mg
- Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at BirthCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00102960Written as Abacavir sulfate
- A Study of Abacavir Plus Indinavir Sulfate Plus Efavirenz in HIV-Infected PatientsCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00001086Written as Abacavir sulfate
- Blood Levels of Abacavir After One Dose in HIV-Infected Children and AdolescentsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT00011479Written as Abacavir sulfate
- Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients Who Have Never Received Anti-HIV DrugsCompletedNot applicableNational Institute of Allergy and Infectious Diseases (NIAID)NCT00004855Written as Abacavir sulfate
- Mycophenolate Mofetil and Abacavir Treatment in HIV Patients With Failed Anti-HIV TreatmentWithdrawnPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00021489Written as Abacavir sulfate
- Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected With HIVCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000940Written as Abacavir sulfate
- A Study on Amprenavir in Combination With Other Anti-HIV Drugs in HIV-Positive PatientsCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000912Written as Abacavir sulfate
- A Study to Test the Safety, Tolerance, and Metabolism of Abacavir (1592U89, ABC) With Standard Zidovudine (ZDV) Therapy in Newborn Infants Born to HIV-1 Infected WomenCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT00000864Written as Abacavir sulfate
- Viral Dynamics and Pharmacokinetics of Abacavir and TenofovirCompletedPhase 2University of California, San DiegoNCT00214890Written as Abacavir
- Study of Options for Second-Line Effective Combination Therapy (SELECT)CompletedPhase 3Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNCT01352715Written as Abacavir
- A HIV Study Of A Fixed-Dose Combination Tablet In Antiretroviral Experienced PatientsCompletedPhase 3ViiV HealthcareNCT00046176Written as abacavir
See all 77 studies that test Abacavir →
Given beside what is tested · 7 — Abacavir is usual care or a partner of the new treatment
- Clinical Trial to Evaluate the Efficacy, Pharmacokinetics (PK) Interactions and Safety of Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV-1-Infected Solid Organ Transplant PatientsCompletedPhase 4Fundacion Clinic per a la Recerca BiomédicaNCT03360682Written as Abacavir 600 MG
- A Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Antiviral Activity of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 YearsCompletedPhase 2Janssen Sciences Ireland UCNCT00799864Written as Abacavir
- Treatment of Hepatitis B Virus (HBV) Before Beginning Anti-HIV Drugs in Patients With Both HBV and HIVWithdrawnNot applicableNational Institute of Allergy and Infectious Diseases (NIAID)NCT00051090Written as Abacavir
- A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV InfectionCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00006154Written as Abacavir sulfate
- A Study to Evaluate Antiviral Activity of Darunavir + Ritonavir in HIV-1 Infected AdolescentsCompletedPhase 2Tibotec Pharmaceuticals, IrelandNCT00915655Written as abacavir
- Anti-HIV Drugs for Ugandan Patients With HIV and TuberculosisCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00078247Written as Abacavir
- Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected SubjectsCompletedPhase 1St Stephens Aids TrustNCT00765271Written as Abacavir
As the comparator · 5 — what is tested is compared with Abacavir
- Neurological Monitoring in Patients Switching From Dolutegravir Based Regimen to Bictegravir Based RegimenStatus unknownPhase 3Azienda Ospedaliera Universitaria SeneseNCT04155554Written as Dolutegravir/lamivudine/abacavir
- Switching From Tenofovir Disoproxil Fumarate to Abacavir or Tenofovir AlafenamideStatus unknownPhase 4Erasmus Medical CenterNCT02957864Written as abacavir
- Bioequivalence and Pharmacokinetic Study of Prurisol™ and Abacavir Sulfate in Healthy VolunteersCompletedPhase 1Cellceutix CorporationNCT02101216Written as Ziagen
- FREE Study: Efficacy and Toxicity of TrizivirCompletedPhase 3Rijnstate HospitalNCT00405925Written as zidovudine,lamivudine,abacavir
- Study to Evaluate Changes in Limb Fat When Switching From a Thymidine AnalogueCompletedPhase 2Gilead SciencesNCT00647946Written as abacavir 300mg twice daily
Codes
What other systems call Abacavir · ClinicalTrials.gg INT006891
- MeSH (NLM) D000099227AbacavirConfirmed NLM, Wikidata
- UNII (FDA) WR2TIP26VSABACAVIRConfirmed FDA, NLM, Wikidata
- UNII (FDA) X9A7099R51ABACAVIR, (+)-One source NLM
- RxNorm 190521Confirmed FDA, Wikidata
- Wikidata Q304330abacavirConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61523AbacavirOne source FDA
- DrugBank DB01048One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000099227 | Abacavir | Confirmed NLM, Wikidata |
| UNII (FDA) | WR2TIP26VS | ABACAVIR | Confirmed FDA, NLM, Wikidata |
| UNII (FDA) | X9A7099R51 | ABACAVIR, (+)- | One source NLM |
| RxNorm | 190521 | — | Confirmed FDA, Wikidata |
| Wikidata | Q304330 | abacavir | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61523 | Abacavir | One source FDA |
| DrugBank | DB01048 | — | One source Wikidata |
Also registered as abacavir hydrochloride monohydrate (UNII GZP7A66C3C), abacavir succinate (UNII 40FH6D8CHK), abacavir sulfate (UNII J220T4J9Q2 · RxNorm 221052) and abacavir sulfate, (+)- (UNII PMA9EH08PM).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.