An interventional study of Artificial saliva containing cumin and ginger extract and Placebo in Xerostomia, sponsored by Chulalongkorn University. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-06-24.
Sponsored by Chulalongkorn University · Not applicable, Interventional, and Treatment
The objectives of this study are to evaluate efficacy and safety of artificial saliva containing cumin and ginger extract in head and neck cancer patients with xerostomia.
There are 52 patients in this study. They are divided into 2 groups which are artificial saliva containing cumin and ginger extract group (test group) 26 patients and placebo group 26 patients. The patients spray the sample into the mouth 3 times/day for 14 day. Amount of saliva, pH of saliva, xerostomia questionnaires, WHO Oral Mucositis Grading Scale, quality of life, adverse events, and satisfaction were assessed.
2,344 studies on the registry are indexed under Head and Neck Neoplasms; 551 are open to participants now.
This study's planned enrollment of 52 is above the median of 47 across 1,751 interventional studies indexed under Head and Neck Neoplasms.
Browse Head and Neck Neoplasms studies →Chulalongkorn University is the lead sponsor of 312 studies on the registry; 59 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Artificial saliva containing cumin and ginger extract in spray bottle
Other: Artificial saliva containing cumin and ginger extract
Placebo containing composition close to the test group without cumin and ginger extract in spray bottle
Other: Placebo
Artificial saliva containing cumin and ginger extract in spray bottle
Placebo containing composition close to the test group without cumin and ginger extract in spray bottle
Amount of saliva
Spit saliva to the bottle for 5 min
Time frame: 14 days
Acid and base characteristic of saliva
Spit saliva to the bottle, then take 1 piece of pH strip and dip it into the saliva for 30 seconds. Compare the color of the dipped pH strip to the color chart on pH strip box. The result shows value at pH 1-14.
Time frame: 14 days
Xerostomia questionnaires
Assessment xerostomia symptom by patient (scoring 1 to 10 point (low to high xerostomia severity)).
Time frame: 14 days
Oral Mucositis Grading Scale
Evaluate oral mucosa by physician (scoring 0 to 4 point (none to life-threatening)).
Time frame: 14 days
Adverse reaction: Skin reaction
Found or not found
Time frame: 14 days
Adverse reaction: Respiratory reaction
Found or not found
Time frame: 14 days
Adverse reaction: Gastrointestinal trat reaction
Found or not found
Time frame: 14 days
Quality of life of the patient
Assessment quality of life by patient (scoring 1 to 120 point (high to low quality of life)).
Time frame: 14 days
Satisfaction of the patient
Assessment satisfaction by patient (scoring 1 to 10 point (low to high satisfaction)).
Time frame: 14 days
No study locations are listed for this record.
This study is not yet recruiting, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Chulalongkorn University