Vaso-Occlusive Crises: all 104 studies
Page 1 of 2. Open to participants first (31), then studies with results posted, then the rest; newest registration first within each.
- Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive CrisisNot yet recruitingNCT07826988Phase 4
- Buprenorphine for the Management of Pain in Children With Sickle Cell DiseaseNot yet recruitingNCT07799571Phase 1
- Pleuropulmonary Ultrasound Imaging in Patients With Sickle Cell Disease in a Vaso-occlusive Crisis. "ECHODREP"Not yet recruitingNCT07782489
- Standard of Care Comparative Arm of Phase 1/2 Gene Therapy Trial DREPAMIR" in Severe Sickle Cell Disease PatientsNot yet recruitingNCT07752043Not applicable
- Virtual Reality for SCD VOCRecruitingNCT07674277Not applicable
- Evaluation of the Efficacy of Iloprost in the Management of Vaso-occlusive Crises in Adult Patients With Sickle Cell DiseaseNot yet recruitingNCT07498309Phase 3
- Optimal Timing of Ketamine Initiation for SCD PainNot yet recruitingNCT07450430Phase 3
- Efficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected Globin Gene and a Silencing RNA.RecruitingNCT07432867Phase 1/2
- Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young AdultsRecruitingNCT07369024Phase 2
- Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell DiseaseRecruitingNCT07274254Phase 3
- Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive CareRecruitingNCT07246265Not applicable
- Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)RecruitingNCT07224360Phase 2
- Outcomes of Vaso-occlusive Crisis in Pediatric Sickle Cell DiseaseNot yet recruitingNCT07200869
- Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive CrisisRecruitingNCT07188766Not applicable
- Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell DiseaseRecruitingNCT07001631Not applicable
- Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell PatientsRecruitingNCT07001189
- A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive CrisisNot yet recruitingNCT06989567Phase 3
- Pilot Study on the Value of Bedside Pleuropulmonary Ultrasound in Patients With Sickle Cell Disease Presenting With Vaso-occlusive CrisisNot yet recruitingNCT06755385
- Hypoxic Red Blood Cells in Sickle Cell AnemiaNot yet recruitingNCT06743113Not applicable
- Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive CrisisRecruitingNCT06699849Phase 2
- Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell DiseaseNot yet recruitingNCT06579703Phase 4
- A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)RecruitingNCT06439082Phase 3
- Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell DiseaseRecruitingNCT06399107Phase 1/2
- Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency DepartmentNot yet recruitingNCT06315920Phase 3
- Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the PediatricNot yet recruitingNCT06181695Phase 3
- Study of Erythrocyte Parameters and Hypercoagulability in Sickle Cell Disease (SCD-TGA)RecruitingNCT05376046
- Sickle Cell Improvement: Enhancing Care in the Emergency DepartmentRecruitingNCT05373771Not applicable
- Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD)RecruitingNCT05289700Phase 3
- Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab StudyRecruitingNCT04657822Phase 4
- Lidocaine Intravenous in the Emergency Department For Sickle Cell CrisisNot yet recruitingNCT04614610Phase 2
- Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell DiseaseRecruitingNCT03353584Not applicable
- A Study to Learn About Sickle Cell Disease In Adult PatientsCompletedNCT05407805Results posted
- A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive CrisesCompletedNCT04935879Phase 3Results posted
- A Study of a Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive CrisesTerminatedNCT04927247Phase 3Results posted
- An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease PatientsCompletedNCT04662931Phase 4Results posted
- Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease PatientsActive, not recruitingNCT03814746Phase 3Results posted
- Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell DiseaseTerminatedNCT03615924Phase 3Results posted
- Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises?CompletedNCT03541980Phase 4Results posted
- Ketamine for Acute Painful Crisis in Sickle Cell Disease PatientsCompletedNCT03431285Not applicableResults posted
- Hyperbaric Oxygen Therapy in Sickle Cell PainCompletedNCT03412045Not applicableResults posted
- Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive CrisisCompletedNCT03296345Phase 2Results posted
- Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC)CompletedNCT03264989Phase 2Results posted
- Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in SicklersCompletedNCT02434939Phase 4Results posted
- The Use of Warmed Saline in Vaso-occlusive EpisodesCompletedNCT02316366Not applicableResults posted
- Comparing Acute Pain Management Protocols for Patients With Sickle Cell DiseaseCompletedNCT02222246Phase 4Results posted
- Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell DiseaseCompletedNCT02187003Phase 3Results posted
- Apixaban in Patients With Sickle Cell DiseaseTerminatedNCT02179177Phase 3Results posted
- Nitrous Oxide Analgesia Vaso-occlusive CrisisCompletedNCT01891812Phase 2Results posted
- Microvascular Blood Flow in Sickle Cell AnemiaCompletedNCT01566890Not applicableResults posted
- Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive CrisisCompletedNCT01482091Phase 4Results posted
- Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus PlaceboCompletedNCT01419977Phase 2Results posted
- A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemiaCompletedNCT01179217Phase 3Results posted
- Safety and Efficacy of Sodium Nitrite in Sickle Cell DiseaseTerminatedNCT01033227Phase 1/2Results posted
- Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell DiseaseTerminatedNCT00532883Phase 2Results posted
- Effectiveness of Arginine as a Treatment for Sickle Cell AnemiaCompletedNCT00513617Phase 2Results posted
- Steroid Treatment for Sickle Cell Pain CrisisTerminatedNCT00263562Phase 3Results posted
- Nitric Oxide Inhalation to Treat Sickle Cell Pain CrisesCompletedNCT00094887Phase 2Results posted
- Sex Hormones and Inflammatory Biomarkers in Patients With Sickle Cell DiseaseCompletedNCT06345638
- Virtual Reality as an Adjuvant Therapy for Sickle Cell Vaso-Occlusive Crisis in the Pediatric Emergency DepartmentCompletedNCT05864092Not applicable
- Lipid Balance in Adult Sickle Cell PatientsActive, not recruitingNCT05780775Not applicable
- Inflammation, Platelets and Sickle Cell DiseaseActive, not recruitingNCT05646888
- Mindfulness and Yoga Therapy for Acute Pain in Sickle Cell DiseaseCompletedNCT05572294Not applicable
- DSUVIA in Patients With SCD VOC Present in the EDStatus unknownNCT05388188
- Oral Ketamine for Treatment of Vaso-Occlusive PainCompletedNCT05378555Phase 1
- A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell DiseaseTerminatedNCT05348915Phase 3
- Interest of Famotidine in Children With Sickle Cell DiseaseCompletedNCT05084521Phase 2/3
- A Study of Etavopivat in Patients With Thalassemia or Sickle Cell DiseaseCompletedNCT04987489Phase 2
- Observational Prospective Study Measuring the Impact of the Use of a Hypnotic Script Associated With Virtual Reality on the Pain of the Child's Sickle Cell During a Vaso-occlusive CrisisCompletedNCT04917120Not applicable
- L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC)TerminatedNCT04852172Phase 1/2
- Evaluation of Virtual Reality to Save Morphinic in the Treatment of Vaso-occlusive Seizures of Sickle Cell Patients Consulting in the Emergency RoomCompletedNCT04756375Not applicable
- A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)Active, not recruitingNCT04624659Phase 3
- Low Dose Ketamine and Acute Pain CrisisCompletedNCT04330183Phase 4
- Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell AnemiaCompletedNCT04301336Phase 2/3
- Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease.WithdrawnNCT04293172Phase 3
- Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PEDTerminatedNCT04150757Phase 3
- Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults.TerminatedNCT04076748Phase 3
- Ketamine Infusion for Sickle Cell Pain CrisisWithdrawnNCT04005209Phase 4
- Music Therapy: Sickle Cell and Pain CrisisCompletedNCT03901560
- Sleep Apnea in Sickle Cell DiseaseTerminatedNCT03753854Not applicable
- Music Therapy in Sickle Cell Disease Vaso-occlusive CrisisStatus unknownNCT03639805Not applicable
- Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest ImagingCompletedNCT03478917
- Transillumination Device for Peripheral Intravenous Placement in Patients With Sickle Cell Disease (PERFID)CompletedNCT03477552Not applicable
- Implication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia:CompletedNCT03368924Not applicable
- Hydroxyurea in the Emergency Room to Lessen Pain in Sickle Cell CrisisStatus unknownNCT03062501Phase 2
- Validation of a Predictive Score of Acute Chest SyndromeStatus unknownNCT03032055
- A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive CrisesTerminatedNCT02698761Not applicable
- A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease PatientsCompletedNCT02672540Phase 2
- Sleep Study in Adult Patients With Major Sickle Cell Disease With Paroxysmal Nocturnal EventsCompletedNCT02539771Not applicable
- Evaluation of Repeat Administration of Purified Poloxamer 188CompletedNCT02449616Phase 3
- Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell DiseaseTerminatedNCT02433158Phase 3
- Single-center Prospective Evaluation of Sickle Cell Patient Care in the CHU Brugmann Emergency DepartmentCompletedNCT02386657
- Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain CrisisWithdrawnNCT01932554Phase 2
- Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle CrisisWithdrawnNCT01925001Phase 2
- Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC)CompletedNCT01737814Phase 3
- A Study of Varespladib Infusion in Subjects With Sickle Cell Disease.TerminatedNCT01522196Phase 2
- Non Invasive Positive Pressure Ventilation for Prevention of Acute Chest Syndrome in Sickle Cell DiseaseTerminatedNCT01501643Not applicable
- Safety Study of MP4CO in Adult Sickle Cell PatientsCompletedNCT01356485Phase 1
- Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell DiseaseCompletedNCT01319448Phase 1/2
- Study of GMI-1070 for the Treatment of Sickle Cell Pain CrisisCompletedNCT01119833Phase 2
- Comparison of Patient Controlled Analgesia (PCA) Versus Bolus Narcotic Therapy for the Treatment of Vaso-Occlusive Crisis (VOC)WithdrawnNCT00711698Phase 2