Thymoma: all 127 studies

Page 1 of 2. Open to participants first (37), then studies with results posted, then the rest; newest registration first within each.

• Phase II Trial of Hypofractionated Radiotherapy Guided by Optical Surface Imaging and Fan-beam CT for Thymoma With Pleural MetastasisNot yet recruitingNCT07879417Phase 2
• Incidence and Predictors of Early Clinical Relapse Within Six Months After Thymectomy in Patients With Myasthenia GravisNot yet recruitingNCT07853378
• A Phase II, Investigator-Initiated Exploratory Study of Sacituzumab Tirumotecan for Previously Treated Unresectable Thymic CarcinomasNot yet recruitingNCT07750353Phase 2
• Hypofractionated Adjuvant Radiotherapy for Thymic Epithelial TumorsNot yet recruitingNCT07693855Not applicable
• Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic CarcinomaRecruitingNCT07598955Phase 1/2
• Thymic Disease, Autoimmunity, and Neuromuscular Junction Integrity in Myasthenia GravisNot yet recruitingNCT07571525
• Neoadjuvant Adebrelimab Plus CRT for Locally Advanced Thymic CarcinomaNot yet recruitingNCT07479628Phase 2
• 6 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial TumorsNot yet recruitingNCT07463313Phase 2/3
• Electrocautery Resection Combined With HITHOC for Thymic Epithelial Tumors With Pleural MetastasisNot yet recruitingNCT07328074
• Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic CarcinomaRecruitingNCT07324629Phase 2
• HEARTS Trial for Thoracic CancersRecruitingNCT07132918Phase 2
• Neoadjuvant Radiotherapy for Locally Advanced Unresectable ThymomaRecruitingNCT06924619Phase 2
• Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaRecruitingNCT06885697Phase 1
• Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic CarcinomaRecruitingNCT06838910Phase 2
• Glucocorticoids Combined With Concurrent Chemoradiotherapy for Unresectable ThymomaRecruitingNCT06730308Phase 2
• Hypofractionated Radiotherapy for Thymic Epithelial TumorsRecruitingNCT06692062Not applicable
• Myasthenia Gravis Foundation of America Global MG Patient RegistryRecruitingNCT06617741
• Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)RecruitingNCT06402708Phase 3
• Artificial Intelligence Prediction Tool in Thymic Epithelial TumorsRecruitingNCT06301945
• A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial TumorsRecruitingNCT06248515Phase 2
• Perioperative Efgartigimod for Thymoma and Myasthenia GravisNot yet recruitingNCT06221501Phase 2
• Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial TumorsRecruitingNCT06186726Phase 2
• Application of 68Ga-Pentixafor PET/CT for ThymomaRecruitingNCT06086327Early Phase 1
• Robot-assisted vs VATS for ThymomaRecruitingNCT06029621Not applicable
• Neoadjuvant Treatment For Locally Advanced Thymic CancerRecruitingNCT06019468Phase 2
• Folinic Acid for Prevention of Pemetrexed-induced ToxicityRecruitingNCT06010277Phase 4
• First-line CBDCA/PTX/LEN/Pembrolizumab Combination for Previously Untreated Advanced or Recurrent Thymic Carcinomas (Artemis)RecruitingNCT05832827Phase 2
• The Efficacy and Safety of Nanoparticle Albumin-bound (NAB)-Paclitaxel Plus Cisolation Versus CEP (Cisplatin, Epirubicin,Cyclophosphamide) in Induction Therapy for Thymoma: a Study for a Single-center Prospective Phase II Randomized Controlled Train.Not yet recruitingNCT05816694Phase 2
• A Study of KC1036 in Patients with Advanced Thymic TumorsRecruitingNCT05683886Phase 2
• Molecular Analysis and Treatment Options of Thymic MalignanciesRecruitingNCT05667948
• Predictors and Prognostic Factors of Myasthenia Gravis OutcomeRecruitingNCT05214612
• PT-112 in Subjects With Thymoma and Thymic CarcinomaRecruitingNCT05104736Phase 2
• Study on Proton Radiotherapy of Thymic MalignanciesRecruitingNCT04822077Not applicable
• Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic CancerRecruitingNCT03295227Phase 1
• Adjuvant Radiotherapy for Stage II/III Thymoma After Complete ResectionRecruitingNCT02633553Not applicable
• Tissue Procurement and Natural History Study of Patients With Malignant MesotheliomaRecruitingNCT01950572
• Molecular Analysis of Thoracic MalignanciesEnrolling by invitationNCT01385722
• SP Thoracic IDE StudyActive, not recruitingNCT05150210Not applicableResults posted
• A Study of KN046 in Patients With Thymic Carcinoma Who Failed Immune Checkpoint InhibitorsTerminatedNCT04925947Phase 2Results posted
• Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by SurgeryCompletedNCT03694002Phase 2Results posted
• Phase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic TumorsCompletedNCT03583086Phase 1/2Results posted
• Selinexor in Patients With Advanced Thymic Epithelial Tumor Progressing After Primary ChemotherapyTerminatedNCT03193437Phase 2Results posted
• Ribociclib in Treating Patients With Advanced Neuroendocrine Tumors of Foregut OriginCompletedNCT02420691Phase 2Results posted
• Pembrolizumab and Epacadostat in Patients With Thymic CarcinomaStatus unknownNCT02364076Phase 2Results posted
• A Study of BKM120 (Buparlisib) in Relapsed or Refractory ThymomasCompletedNCT02220855Phase 2Results posted
• Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without ChemotherapyTerminatedNCT02062632Phase 2Results posted
• Efficacy of Medical Treatment With SOM230 LAR in Patients With Primary Inoperable Thymoma and/or With Local Recurrent Thymoma to Reduce Tumor SizeCompletedNCT02021942Phase 2Results posted
• Sunitinib for Advanced Thymus Cancer Following Earlier TreatmentCompletedNCT01621568Phase 2Results posted
• A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic MalignanciesCompletedNCT01364727Phase 2Results posted
• Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic MalignanciesCompletedNCT01306045Phase 2Results posted
• Study Of Oral PHA-848125AC In Patients With Malignant Thymoma Previously Treated With Multiple Lines Of ChemotherapyTerminatedNCT01301391Phase 2Results posted
• A Phase 1/2 Study of PXD101 (Belinostat) in Combination With Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic, MalignanciesTerminatedNCT01100944Phase 1/2Results posted
• Phase II Study Of Oral PHA-848125AC In Patients With Thymic CarcinomaTerminatedNCT01011439Phase 2Results posted
• Multicenter Phase II Study of IMC-A12 in Patients With Thymoma and Thymic Carcinoma Who Have Been Previously Treated With ChemotherapyCompletedNCT00965250Phase 2Results posted
• Saracatinib in Treating Patients With Relapsed or Refractory Thymoma or Thymic CancerTerminatedNCT00718809Phase 2Results posted
• Belinostat (PXD101) to Treat Tumors of the Thymus at an Advanced StageCompletedNCT00589290Phase 2Results posted
• Phase II Study of Alimta (Pemetrexed) Treatment of Advanced Thymoma and Thymic CarcinomaCompletedNCT00198133Phase 2Results posted
• Carboplatin Combined With Paclitaxel in Treating Patients With Advanced ThymomaCompletedNCT00010257Phase 2Results posted
• Lucitanib (AL3810) in Patients With Advanced Thymic Carcinoma After ChemotherapyCompletedNCT07824505Phase 2
• Depressive Tendency and Counseling Outcomes in Thymoma-Associated MGCompletedNCT07649187Not applicable
• CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid TumorsSuspendedNCT07181720Phase 1
• Survival Nomogram for Patients With Thymic CarcinomaCompletedNCT07179341Not applicable
• IMMUNORARE5: A National Platform of 5 Academic Phase II Trials Coordinated by Lyon University Hospital to Assess the Safety and the Efficacy of the IMMUNOtherapy With Domvanalimab + Zimberelimab Combination in Patients With Advanced RARE CancersActive, not recruitingNCT06790706Phase 2
• Clinical Investigation of the da Vinci Surgical SystemActive, not recruitingNCT05682742Not applicable
• A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersActive, not recruitingNCT05544929Phase 1
• Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)CompletedNCT05461430
• A Prospective, Single-Center Investigation of the da Vinci SP® Surgical System in Anterior Mediastinal DiseaseActive, not recruitingNCT05455840Not applicable
• Abscopal Effect of Radiotherapy in Combination With rhGM-CSF for Advanced Thymic Epithelial TumoursStatus unknownNCT05407649Phase 2
• Comparison of Single Port and Two Ports Robotic Assisted Thoracic Surgery for ThymectomyStatus unknownNCT05262582Not applicable
• IL-8+ naïve T Cells as a Biomarker for Thymoma IdentificationCompletedNCT05255965
• Surgery for Masaoka-Koga I-II ThymomaCompletedNCT05001113Not applicable
• Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to DrugsWithdrawnNCT04985357
• Combination of Pembrolizumab and Lenvatinib, in Pre-treated Thymic CArcinoma paTIentsCompletedNCT04710628Phase 2
• Embedded Palliative Care in Managing Symptoms in Participants With Recurrent Stage III-IV Thoracic Malignancies and Their CaregiversCompletedNCT04662645Not applicable
• Prognostic Factors in Patients Submitted to Surgical Treatment for ThymomaCompletedNCT04577495
• Chemotherapy Combined With Pembrolizumab in Treating Patients With Thymoma and Thymic CarcinomaStatus unknownNCT04554524Phase 4
• KN046 (a Humanized PD-L1/CTLA4 Bispecific Single Domain Fc Fusion Protein Antibody) in Subjects With Thymic CarcinomaTerminatedNCT04469725Phase 2
• Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072SCompletedNCT04430842Phase 1
• Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic CarcinomaActive, not recruitingNCT04417660Phase 2
• 177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive TumoursCompletedNCT04375267Phase 1
• Thymectomy With and Without Povidone-iodine Pleural Lavage in Stage IVA Thymic MalignanciesWithdrawnNCT04371458Phase 1/2
• A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic CarcinomaCompletedNCT04321330Phase 2
• Single Cell Sequencing Analysis of ThymomaStatus unknownNCT04162691
• Cardiac Rehabilitation for Patients Receiving Radiation Therapy for Thoracic CancersTerminatedNCT04072393Not applicable
• An Investigational Scan (MRI) in Imaging Patients With Newly-Diagnosed or Recurrent ThymomaActive, not recruitingNCT03968315Not applicable
• Ramucirumab and Carbo-Paclitaxel for Untreated Thymic Carcinoma / B3 Thymoma With Carcinoma (RELEVENT)Active, not recruitingNCT03921671Phase 2
• Hypofractionated Chemoradiotherapy and Thymosin α1 in Unresectable or Recurrent Thymic Epithelial TumorStatus unknownNCT03663764Phase 2
• The Curative Effect of Extended Thymectomy Performed Through Subxiphoid-right VATS Approach With Elevation of SternumStatus unknownNCT03613272Not applicable
• A Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsCompletedNCT03517488Phase 1
• Early Versus Late Extubation in Myasthenia Gravis PatientsCompletedNCT03468452
• Selinexor in Patients With Advanced Thymoma and Thymic CarcinomaStatus unknownNCT03466827Phase 2
• Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic CancerActive, not recruitingNCT03463460Phase 2
• Trial of Sunitinib in Patients With Type B3 Thymoma or Thymic Carcinoma in Second and Further Lines (Style Trial)Status unknownNCT03449173Phase 2
• Confocal Laser Endomicroscopy in Pleural MalignanciesStatus unknownNCT03290183
• Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial TumorsCompletedNCT03288662Not applicable
• Genomic Profiling of Nodular Thyroid Disease and Thyroid CancerStatus unknownNCT03170804
• Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM)Active, not recruitingNCT03134118Phase 2
• Prospective Study of Stereotactic Body Radiation Therapy for Thymoma Inoma: Therapeutic Effect and Toxicity AssessmentCompletedNCT03078699Not applicable
• A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based ChemotherapyActive, not recruitingNCT03076554Phase 2
• Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid TumorsCompletedNCT03023319Phase 1

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