CClinicalTrials.gg
Sign In
CompletedNCT03288662Updated Sep 20, 2017

Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial Tumors

An interventional study of CT and histopathological classification in Thymoma, sponsored by Military Hospital 103. Completed. Open to participants aged 21 Years to 71 Years. Per ClinicalTrials.gov, last updated 2017-09-20.

Sponsored by Military Hospital 103 · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
2
Allocation
Not applicable
Ages
21 Years to 71 Years
Sex
All
01

Study summary

the World Health Organization (WHO) has proposed a classification of histopathological thymic tumor and it significance in prognosis. Chest computed tomography (CT) is the most common method to evaluate thymic epithelial tumors before operation. Therefore, the question is to predict the histopathological type of thymic epithelial tumors before surgery based on CT-scan images , to help determine treatment strategy and prognosis. In Vietnam, there are no published literature on this issue.

Read the detailed description
  1. Introduction: the World Health Organization (WHO) has proposed a classification of histopathological thymic tumor and it significance in prognosis. Chest computed tomography (CT) is the most common method to evaluate thymic epithelial tumors before operation. Therefore, the question is to predict the histopathological type of thymic epithelial tumors before surgery based on CT-scan images , to help determine treatment strategy and prognosis. In Vietnam, there are no published literature on this issue.

  2. Materials and methods:

    2.1. Cross-sectional descriptive study on 53 patients with diagnosed of thymoma by CT and had postoperative histopathology results as thymic epithelial tumors

    2.2. Time and Place: in Departement of CTVS, Military Hospital 103, Vietnam from 10/2013 to 7/2017.

    2.3. methods:

    • study in chest CT scan:

      • Measure the maximun diameter of the tumor
      • The contour: smooth contour or irregular contour
      • The shape: round, oval and plaque base on the ratio between long axis and short axis of the tumor
      • Some other characteristics: Degree of enhancement, Level of drug absorbed, Calcification, Invasion the local organs and Capsular destruction.

    • Histopathological study: based on the 2004 WHO classification:

      • Thymoma: type A, AB, B1, B2, B3
      • Thymic carcinoma
    • Data processing: use software Epi Info 2000.

  3. Expectation of results

    • Relationship between the size and histopathological type of thymic epithelial tumors.
    • Comparison of some characteristics of the tumor on preoperative chest CT scans and histopathological type of thymic epithelial tumors
02

Conditions studied

  • Thymoma

Browse trials for

Keywords

  • Computed tomography
  • thymic epithelial tumors
03

Who can participate

Ages eligible
21 Years to 71 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • All of patient have a chest CT scan pre-operation and a result of thymic epithelial tumors postoperative histopathology

Exclusion criteria

Exclusion Criteria:

  • Incomplete or loss the CT and postoperative histopathology
04

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
2 participants (actual)

Study arms

  • Experimental
    CT and histopathological classification

    With each histopathological type of thymic epithelial tumors, we measure the maximun diameter in chest CT scan. Comparison of some characteristics of the tumor on preoperative chest CT scans and histopathological type of thymic epithelial tumors .

    Other: CT and histopathological classification

Interventions

  • OtherCT and histopathological classification

    Cross-sectional descriptive study on 53 patients with diagnosed of thymoma by CT and had postoperative histopathology results as thymic epithelial tumors. Base on the characteristics in Chest CT scan in each postoperative histopathology results.

05

What researchers measure

Primary outcomes

  1. maximun diameter of the tumor

    Measure the maximun diameter of the tumor in chest CT scan

    Time frame: 1 month

06

Study locations

No study locations are listed for this record.

07

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03288662
Lead sponsor
Military Hospital 103
Collaborators
Nguyen Truong Giang
Responsible party
Le Viet Anh, MD (Principal Investigator, Military Hospital 103) — Principal investigator
First posted
Sep 20, 2017
Start date
Oct 1, 2013
Primary completion
Jul 1, 2017
Completion
Jul 31, 2017
Last update
Sep 20, 2017

Study contacts

Truong Giang Nguyen, PhD
study chair · VMMU

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2017. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Thymoma→

Other studies from this sponsor

Military Hospital 103

Start the discussion