Thymoma clinical trials
The registry lists 133 studies for Thymoma across more than 10 countries. 37 are recruiting or about to start. 84 of them are mainly about Thymoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
National Cancer Institute (NCI) (15) · Fudan University (4) · Georgetown University (3) · Shanghai Pulmonary Hospital, Shanghai, China (3) · Shanghai Zhongshan Hospital (3) · Sun Yat-sen University (3) · M.D. Anderson Cancer Center (3) · Novartis Pharmaceuticals (3)
What is being tested here
Drugs under test in Thymoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Immune checkpoint inhibitors 3 open · Antimitotic agents 3 open · Antibody-drug conjugates (ADCs) 3 open · Tyrosine kinase inhibitors (TKIs) 2 open · Antimetabolites 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- May 2027Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3) · Phase 3 · Fudan University
- Jun 2027EFG vs IVIG in TAMG · Phase 3 · Shanghai Zhongshan Hospital
- Dec 2026Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic Carcinoma · Memorial Sloan Kettering Cancer Center
- Dec 2026Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic Carcinoma · The First Affiliated Hospital with Nanjing Medical University
- Dec 2026Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma · National Cancer Institute (NCI)
- Dec 2026Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial Tumors · Jian Chen
- Mar 2027A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy · National Cancer Institute (NCI)
- May 2027A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors · Georgetown University
- Jun 2027Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic Carcinoma · Beijing Biotech
- Aug 2027Artificial Intelligence Prediction Tool in Thymic Epithelial Tumors · Erasmus Medical Center
Who these studies take
Of the 25 Thymoma studies recruiting now, 10 (40%) set no upper age limit and 12 (48%) stop at 75 or younger. 3 (12%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (8%) | 2 (8%) |
| 18 | 25 (100%) | 25 (100%) |
| 30 | 25 (100%) | 25 (100%) |
| 40 | 25 (100%) | 25 (100%) |
| 50 | 25 (100%) | 25 (100%) |
| 65 | 25 (100%) | 25 (100%) |
| 75 | 24 (96%) | 24 (96%) |
| 85 | 13 (52%) | 13 (52%) |
Across all 133 studies, recruiting or not: 24% stop at 75 or younger and 2% at 65; 8% take children; 0% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Thymoma studies take
Of 32 phase 2 interventional studies under Thymoma, half reached primary completion within 59 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 59 mo36–96 · 32 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Stopped1
- HEARTS Trial for Thoracic CancersSuspendedOct 30, 2026NCT07132918
Newly registered2
- STAR0602 With Nivolumab in Non Small Cell Lung Cancer and in Metastatic Castrate-Resistant Prostate Cancer, and STAR0602 Alone in Thymic CarcinomaOct 29, 2026NCT07902921
- Phase II Trial of Hypofractionated Radiotherapy Guided by Optical Surface Imaging and Fan-beam CT for Thymoma With Pleural MetastasisOct 16, 2026NCT07879417
Studies
Recruiting first, then most recently updated. Showing 50 of 133. Browse all 133 → or search them.
- STAR0602 With Nivolumab in Non Small Cell Lung Cancer and in Metastatic Castrate-Resistant Prostate Cancer, and STAR0602 Alone in Thymic CarcinomaNot yet recruitingNCT07902921Phase 1/21 country
- Tissue Procurement and Natural History Study of Patients With Malignant MesotheliomaRecruitingNCT019505721 country
- Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaRecruitingNCT06885697Phase 11 country
- Phase II Trial of Hypofractionated Radiotherapy Guided by Optical Surface Imaging and Fan-beam CT for Thymoma With Pleural MetastasisNot yet recruitingNCT07879417Phase 2
- PT-112 in Subjects With Thymoma and Thymic CarcinomaRecruitingNCT05104736Phase 21 country
- Incidence and Predictors of Early Clinical Relapse Within Six Months After Thymectomy in Patients With Myasthenia GravisNot yet recruitingNCT07853378
- A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial TumorsRecruitingNCT06248515Phase 21 country
- Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic CarcinomaRecruitingNCT07324629Phase 21 country
- A Phase II, Investigator-Initiated Exploratory Study of Sacituzumab Tirumotecan for Previously Treated Unresectable Thymic CarcinomasNot yet recruitingNCT07750353Phase 21 country
- Hypofractionated Adjuvant Radiotherapy for Thymic Epithelial TumorsNot yet recruitingNCT07693855Not applicable1 country
- Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic CancerRecruitingNCT03295227Phase 11 country
- Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic CarcinomaRecruitingNCT07598955Phase 1/21 country
- Neoadjuvant Treatment For Locally Advanced Thymic CancerRecruitingNCT06019468Phase 21 country
- Thymic Disease, Autoimmunity, and Neuromuscular Junction Integrity in Myasthenia GravisNot yet recruitingNCT075715251 country
- Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)RecruitingNCT06402708Phase 31 country
- Adjuvant Radiotherapy for Stage II/III Thymoma After Complete ResectionRecruitingNCT02633553Not applicable1 country
- Randomized, Multicenter, Phase III Trial to Assess Conformal Post-operative Radiotherapy vs. Surveillance After Complete Resection of Stage II/III Thymoma (RADIO-RYTHMIC-01)RecruitingNCT04731610Not applicable1 country
- Neoadjuvant Adebrelimab Plus CRT for Locally Advanced Thymic CarcinomaNot yet recruitingNCT07479628Phase 2
- 6 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial TumorsNot yet recruitingNCT07463313Phase 2/31 country
- Electrocautery Resection Combined With HITHOC for Thymic Epithelial Tumors With Pleural MetastasisNot yet recruitingNCT073280741 country
- Molecular Analysis of Thoracic MalignanciesEnrolling by invitationNCT013857221 country
- Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic CarcinomaRecruitingNCT06838910Phase 21 country
- EFG vs IVIG in TAMGNot yet recruitingNCT07231523Phase 31 country
- Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial TumorsRecruitingNCT06186726Phase 21 country
- Molecular Analysis and Treatment Options of Thymic MalignanciesRecruitingNCT056679481 country
- Neoadjuvant Radiotherapy for Locally Advanced Unresectable ThymomaRecruitingNCT06924619Phase 21 country
- Serratus Posterior Superior Intercostal Plane Block in Robotic-Assisted ThymectomyRecruitingNCT06545409Not applicable1 country
- Glucocorticoids Combined With Concurrent Chemoradiotherapy for Unresectable ThymomaRecruitingNCT06730308Phase 21 country
- Hypofractionated Radiotherapy for Thymic Epithelial TumorsRecruitingNCT06692062Not applicable1 country
- Predictors and Prognostic Factors of Myasthenia Gravis OutcomeRecruitingNCT052146121 country
- Artificial Intelligence Prediction Tool in Thymic Epithelial TumorsRecruitingNCT063019451 country
- Robot-assisted vs VATS for ThymomaRecruitingNCT06029621Not applicable1 country
- First-line CBDCA/PTX/LEN/Pembrolizumab Combination for Previously Untreated Advanced or Recurrent Thymic Carcinomas (Artemis)RecruitingNCT05832827Phase 21 country
- Application of 68Ga-Pentixafor PET/CT for ThymomaRecruitingNCT06086327Early Phase 11 country
- Folinic Acid for Prevention of Pemetrexed-induced ToxicityRecruitingNCT06010277Phase 41 country
- The Efficacy and Safety of Nanoparticle Albumin-bound (NAB)-Paclitaxel Plus Cisolation Versus CEP (Cisplatin, Epirubicin,Cyclophosphamide) in Induction Therapy for Thymoma: a Study for a Single-center Prospective Phase II Randomized Controlled Train.Not yet recruitingNCT05816694Phase 21 country
- Study on Proton Radiotherapy of Thymic MalignanciesRecruitingNCT04822077Not applicable1 country
- HEARTS Trial for Thoracic CancersSuspendedNCT07132918Phase 21 country
- A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based ChemotherapyActive, not recruitingNCT03076554Phase 21 country
- A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersActive, not recruitingNCT05544929Phase 112 countries
- Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic CarcinomaActive, not recruitingNCT04417660Phase 21 country
- Embedded Palliative Care in Managing Symptoms in Participants With Recurrent Stage III-IV Thoracic Malignancies and Their CaregiversCompletedNCT04662645Not applicable1 country
- Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With MalignanciesCompletedNCT01242072Phase 11 country
- An Investigational Scan (MRI) in Imaging Patients With Newly-Diagnosed or Recurrent ThymomaActive, not recruitingNCT03968315Not applicable1 country
- Lucitanib (AL3810) in Patients With Advanced Thymic Carcinoma After ChemotherapyCompletedNCT07824505Phase 21 country
- SP Thoracic IDE StudyActive, not recruitingNCT05150210Not applicable1 country
- CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid TumorsSuspendedNCT07181720Phase 11 country
- Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic CancerActive, not recruitingNCT03463460Phase 21 country
- Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic CarcinomaActive, not recruitingNCT01025089Phase 21 country
- IMMUNORARE5: A National Platform of 5 Academic Phase II Trials Coordinated by Lyon University Hospital to Assess the Safety and the Efficacy of the IMMUNOtherapy With Domvanalimab + Zimberelimab Combination in Patients With Advanced RARE CancersActive, not recruitingNCT06790706Phase 21 country