Thoracic Neoplasms clinical trials
The registry lists 115 studies for Thoracic Neoplasms across more than 10 countries. 30 are recruiting or about to start. 21 of them are mainly about Thoracic Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its 18 narrower conditions too, such as Carcinoma, Non-Small-Cell Lung: 13,109 studies, 3,378 open.
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Status
Who runs them
Revolution Medicines, Inc. (6) · AstraZeneca (6) · Fundación GECP (5) · Eli Lilly and Company (4) · Blueprint Medicines Corporation (4) · Sichuan Cancer Hospital and Research Institute (4) · Hoffmann-La Roche (3) · Syndax Pharmaceuticals (3)
What is being tested here
Drugs under test in Thoracic Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Daraxonrasib | 2 | 0 | 2 |
| Elironrasib | 1 | 0 | 2 |
| Olomorasib | 1 | 1 | 1 |
| Osimertinib | 1 | 0 | 1 |
| Tambotatug pelitecan | 1 | 0 | 1 |
| Atorvastatin | 1 | 0 | 1 |
| Lisinopril | 1 | 0 | 1 |
| AMG 757 | 1 | 0 | 1 |
| Repotrectinib | 1 | 0 | 1 |
| Budesonide | 1 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 2 open · Immune checkpoint inhibitors 2 open · Antimetabolites 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC) · Phase 3 · Qilu Pharmaceutical Co., Ltd.
- Nov 2027A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer · Phase 3 · Eli Lilly and Company
- Dec 2026Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients · Instituto Nacional de Cancerologia de Mexico
- Dec 2026Erector Spinae Block for Thoracic Surgery · George Washington University
- Feb 2027Post-operative Medium Chain Triglyceride Diet May Reduce Hospital Stay Following Lung Resection · Chinese University of Hong Kong
- Mar 2027Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors · Revolution Medicines, Inc.
- Mar 2027A Novel Tobacco Cessation Resource for Smokers With a Diagnosed or Suspected Thoracic Cancer · Ohio State University Comprehensive Cancer Center
- May 2027Understanding New Cachexia Subtypes Through Observational Epidemiological Research · Kaiser Permanente
- May 2027Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS · Revolution Medicines, Inc.
- Jun 2027TELEhealth Shared Decision-making COaching for Lung Cancer Screening in Primary Care (TELESCOPE) for Hispanics · Rutgers, The State University of New Jersey
Who these studies take
Of the 27 Thoracic Neoplasms studies recruiting now, 18 (67%) set no upper age limit and 6 (22%) stop at 75 or younger. 1 (4%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 25 (93%) | 25 (93%) |
| 30 | 25 (93%) | 25 (93%) |
| 40 | 26 (96%) | 26 (96%) |
| 50 | 27 (100%) | 27 (100%) |
| 65 | 27 (100%) | 27 (100%) |
| 75 | 25 (93%) | 25 (93%) |
| 85 | 19 (70%) | 19 (70%) |
Across all 115 studies, recruiting or not: 15% stop at 75 or younger and 2% at 65; 4% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Thoracic Neoplasms studies take
Of 22 interventional studies with no phase under Thoracic Neoplasms, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 26 mo16–66 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 115. Browse all 115 → or search them.
- A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung CancerRecruitingNCT06119581Phase 329 countries
- Veterans Affairs Lung Cancer Surgery Or Stereotactic RadiotherapyRecruitingNCT02984761Not applicable1 country
- Study of Collection and Analysis of Clinical, Anamnestic, Functional, Biological Data Through the Support of Artificial Intelligence to Evaluate the Possibility of Defining a Digital Twin of the Lung (LUCE)RecruitingNCT075173931 country
- Post-operative Medium Chain Triglyceride Diet May Reduce Hospital Stay Following Lung ResectionNot yet recruitingNCT07159659Not applicable1 country
- Osimertinib Combined With Chemotherapy in Patients Who Had Distant Recurrence After Adjuvant Osimertinib for EGFRm Resectable SIB-IIIA NSCLC.RecruitingNCT07279935Phase 41 country
- Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid TumorsRecruitingNCT06128551Phase 1/27 countries
- A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid TumorsRecruitingNCT07407933Phase 1/29 countries
- Pharmacologic Therapies to Mitigate Radiation- Associated Heart DiseaseRecruitingNCT07685938Phase 21 country
- Understanding New Cachexia Subtypes Through Observational Epidemiological ResearchRecruitingNCT077763531 country
- Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage SCLC PatientsRecruitingNCT07242547Phase 21 country
- A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsRecruitingNCT03093116Phase 1/219 countries
- Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RASRecruitingNCT05379985Phase 1/21 country
- Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With CancerRecruitingNCT05297734Not applicable1 country
- Local Radiofrequency Ablation Plus External Beam Radiation for the Treatment of Painful Thoracic and Lumbar Spine TumorsRecruitingNCT074791991 country
- Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer PatientsRecruitingNCT03803787Phase 21 country
- Erector Spinae Block for Thoracic SurgeryRecruitingNCT05521789Phase 41 country
- Clinical Study of Thiopegfilgrastim for Preventing Bone Marrow Suppression in Thoracic Tumor ChemoradiotherapyRecruitingNCT07205536Phase 21 country
- Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung CancerRecruitingNCT06758700Phase 21 country
- TELEhealth Shared Decision-making COaching for Lung Cancer Screening in Primary Care (TELESCOPE) for HispanicsRecruitingNCT07165691Not applicable1 country
- PALACE: Cemiplimab Trial According to ctDNA LevelsRecruitingNCT06917573Phase 21 country
- Early Intervention Strategies for Lung CancerRecruitingNCT06988943Not applicable1 country
- The Effects of a Family-Centered Tai Chi Exercise on Lung Function and Mental Health of Patients After Thoracoscopic SurgeryRecruitingNCT06104774Not applicable1 country
- Optimizing Radiation Dose and Utilizing Wearable Devices to Reduce Arrhythmia Risk in Patients Undergoing Thoracic Radiotherapy: A Prospective Cohort StudyNot yet recruitingNCT068971891 country
- Preoperative Paravertebral Block in Cancer Surgery of the LungRecruitingNCT04209868Phase 2/31 country
- Radiotherapy Treatments for the Treatment of Thoracic District TumorsRecruitingNCT063352901 country
- Pelvic Cancer Registry for Online Adapted RadiotherapyRecruitingNCT061850621 country
- Safety and Efficacy of SBRT in the Reirradiation for Ultra-central Thoracic Malignant TumorsRecruitingNCT051890541 country
- A Phase Ⅱ Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy for Extensive-Stage Oligometastatic SCLCRecruitingNCT06177925Phase 21 country
- Feasibility and Safety of a Wireless PalpatorNot yet recruitingNCT05321615Not applicable
- Comparison Between McGrath and Macintosh Laryngoscopes for DLT Intubation in Thoracic Surgery Patients.RecruitingNCT05988736Not applicable1 country
- Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC)Active, not recruitingNCT07162883Phase 313 countries
- A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With CancerActive, not recruitingNCT05053230Not applicable1 country
- Small/Middle Tier Cities and County Lung Cancer Quality Improvement Project (QIP) StudyActive, not recruitingNCT064942411 country
- Electronic Symptom Monitoring Program for Triggered Palliative Referrals in Patients With Thoracic CancerCompletedNCT06396598Not applicable1 country
- SPSIPB vs SAPB for Thoracoscopic SurgeryCompletedNCT06546839Not applicable1 country
- A Novel Tobacco Cessation Resource for Smokers With a Diagnosed or Suspected Thoracic CancerActive, not recruitingNCT07455513Not applicable1 country
- A Study to Investigate Efficacy and Safety of Ceralasertib Plus Durvalumab in Participants Aged ≥ 18 Years With Advanced or Metastatic Non-small Cell Lung Cancer Whose Disease Progressed on or After Prior Anti-PD-(L)1 Therapy and Platinum-based ChemotherapyActive, not recruitingNCT05941897Phase 21 country
- Osimertinib With Chemotherapy as First-line Therapy for EGFR Mutation-positive NSCLCActive, not recruitingNCT063760841 country
- Atezolizumab Plus Induction Chemotherapy Plus CT-radiotherapy. (APOLO)CompletedNCT04776447Phase 21 country
- A Study to Investigate the Effects of Durvalumab With Oleclumab Following Chemoradiation in Participants With Locally Advanced Unresectable Non-Small Cell Lung Cancer (LADOGA)Active, not recruitingNCT06606847Phase 21 country
- Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid TumorsActive, not recruitingNCT05462717Phase 113 countries
- New Adjuvant Trial of Chemotherapy vs Chemo-immunotherapyActive, not recruitingNCT04564157Phase 31 country
- Real World Registry for Use of the Ion Endoluminal SystemActive, not recruitingNCT060044401 country
- A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)Active, not recruitingNCT03157128Phase 1/216 countries
- NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid TumorsCompletedNCT04332653Phase 1/21 country
- A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)TerminatedNCT04222972Phase 322 countries
- A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) TumorsActive, not recruitingNCT03899792Phase 1/211 countries
- Expanded Access Program of Taletrectinib in Patients With Advanced or Metastatic ROS1-Positive NSCLCNo longer availableNCT06841874
- Effectiveness of an Educational Intervention Aimed at Increasing the Emotional Competencies of Patients Under Surveillance After Antineoplastic Treatment of Oesogastric or Bronchopulmonary CancerCompletedNCT04556344Not applicable1 country
- Implementing Fragmentomics Into Real World Screening IntervenTions to Evaluate Clinical Utility Among Individuals With Elevated Risk for Lung CancerCompletedNCT06145750Not applicable1 country