Drug
Olomorasib clinical trials
Also written LY3537982.
- studies test it
- 15
- open now
- 5
- in phase 3
- 2
- first study started
- 2023
Keep track of what changes. Save the olomorasib studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Studies by the year they started
15 studies that test it; most in 2026 (5)
| Year | Studies |
|---|---|
| 2023 | 4 |
| 2024 | 2 |
| 2025 | 4 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 11
- Phase 2
- 3
- Phase 3
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 14 · Other 1
Eli Lilly and Company (13) · Janssen Research & Development, LLC (1) · UNC Lineberger Comprehensive Cancer Center (1)
Often tested with
Tested in the same studies.
Pembrolizumab (2) · Fluconazole (1) · Digoxin (1) · Rosuvastatin (1) · Midazolam (1) · Cetuximab (1) · Pemetrexed (1) · Durvalumab (1)
Studies
Open first, then newest update. How each study uses olomorasib is read from its arms, and is right about nine times in ten.
Testing it · 15
- A Study of Olomorasib (LY3537982) in Participants With Advanced Colorectal Cancer and a KRAS G12C MutationNot yet recruitingPhase 2Eli Lilly and CompanyNCT07814417Written as Olomorasib
- A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung CancerRecruitingPhase 3Eli Lilly and CompanyNCT06119581Written as LY3537982
- Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung CancerRecruitingPhase 3Eli Lilly and CompanyNCT06890598Written as Olomorasib
- A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung CancerRecruitingPhase 1/2Janssen Research & Development, LLCNCT07227025Written as Olomorasib
- A Study Comparing Two Ways of Taking Olomorasib (LY3537982) in Healthy ParticipantsRecruitingPhase 1Eli Lilly and CompanyNCT07794592Written as Olomorasib test
- Olomorasib + Pembrolizumab KRAS G12C Mutant, PD-L1 TPS 1-49% Locally Advanced or Metastatic NSCLCSuspendedPhase 2UNC Lineberger Comprehensive Cancer CenterNCT07639242Written as Olomorasib
- A Study of LY3537982 in Chinese Participants With Advanced Solid TumorsCompletedPhase 1Eli Lilly and CompanyNCT06235983Written as LY3537982
- A Study of Multiple Olomorasib (LY3537982) Capsules in Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT07044271Written as Olomorasib
- A Study of Olomorasib (LY3537982) in Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT07439250Written as Olomorasib
- A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney FunctionCompletedPhase 1Eli Lilly and CompanyNCT07137689Written as LY3537982
- A Study of Olomorasib (LY3537982) in Healthy Japanese ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT07124013Written as Olomorasib
- A Study of Olomorasib (LY3537982) in Participants With Hepatic Impairment and Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT06719128Written as Olomorasib
- A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT06111521Written as LY3537982
- A Study of [14C]-LY3537982 in Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT05901311Written as LY3537982
- A Study of the Effect of Food on LY3537982 in Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT05824858Written as LY3537982
Given in every arm · 3 — olomorasib is usual care beside what is tested
- A Study of Dato-DXd in Participants With Solid Tumors [TROPION-PanTumor04 (TP04)]RecruitingPhase 1/2Daiichi SankyoNCT07890714Written as Olomorasib
- Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)Active, not recruitingPhase 1/2Eli Lilly and CompanyNCT04956640Written as LY3537982
- A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy ParticipantsCompletedPhase 1Eli Lilly and CompanyNCT05860933Written as LY3537982
Codes
What other systems call olomorasib · ClinicalTrials.gg INT016158
- UNII (FDA) C2VJ83PSN7OLOMORASIBConfirmed FDA, Wikidata
- Wikidata Q133445577olomorasibConfirmed FDA, Wikidata
- NCI Thesaurus C181751OlomorasibOne source FDA
- DrugBank DB21697One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | C2VJ83PSN7 | OLOMORASIB | Confirmed FDA, Wikidata |
| Wikidata | Q133445577 | olomorasib | Confirmed FDA, Wikidata |
| NCI Thesaurus | C181751 | Olomorasib | One source FDA |
| DrugBank | DB21697 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.