Syphilis: all 126 studies
Page 1 of 2. Open to participants first (34), then studies with results posted, then the rest; newest registration first within each.
- Daily, Weekly, or Event-driven Doxycycline for STI Prevention Among Men Who Have Sex With Men (MSM) Engaging in Chemsex: The DOSE Non-inferiority TrialNot yet recruitingNCT07925255Phase 4
- A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African WomenNot yet recruitingNCT07884240Phase 3
- Pilot HIV Self-Testing And Self-collected STI Testing Strategy for Sex Worker Empowerment StudyNot yet recruitingNCT07829133Not applicable
- Strengthening, Guidance, Health, EmpowermentNot yet recruitingNCT07788599Not applicable
- A Randomized Controlled Trial of Doxycycline Post Exposure Prophylaxis to Prevent Incident Bacterial STIs Among Women in the United StatesNot yet recruitingNCT07704957Phase 4
- Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, SwitzerlandNot yet recruitingNCT07516912
- Doxi-Rio: Study on the Use of Doxycycline to Prevent Sexually Transmitted Infections in Rio de JaneiroRecruitingNCT07500415Not applicable
- The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand.RecruitingNCT07397403Phase 4
- MAGIA H3S Point of Care Test Performance for HIV, HBV, HCV, and Syphilis Screening in Pregnant Women in DR CongoNot yet recruitingNCT07388979
- Feasibility and Acceptability of Point of Care Rapid Syphilis Testing Among Patients Seeking Family Planning Services in Hawai'iRecruitingNCT07358949
- Rapid HIV, Hep C, and Syphilis Screening in a Rural Street Medicine ClinicRecruitingNCT07317687
- Treponemal Shedding, Load, and Viability, in Women and Men-who-have-sex-with-women-only With Early Infectious Syphilis: Implications for TransmissionRecruitingNCT07300254
- Improving Maternal and Child Health Through Point-of-care STI TestingRecruitingNCT07290439Not applicable
- Study of Ceftriaxone and Benzathine Penicillin G During PregnancyRecruitingNCT07207876
- Congenital and Maternal Point of Care Rapid Testing for Syphilis Study, UgandaNot yet recruitingNCT07173764
- Clinical Performance Evaluation of MagIA IVD-MD Multiplex Testing (HIV/HBV/HCV/Syphilis)RecruitingNCT07170748
- This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.RecruitingNCT07089836
- The Feasibility of Implementing Syphilis Point-of-care Testing Into a Prenatal Clinic for People Facing Barriers to CareRecruitingNCT06829602Not applicable
- Peer Delivered HIV/Syphilis Self-Testing with Assisted Partner Notification ServicesEnrolling by invitationNCT06791928Phase 2
- Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in VeteransNot yet recruitingNCT06766331Not applicable
- Doxycycline Prophylaxis for Prevention of Sexually Transmitted InfectionsRecruitingNCT06738407Phase 4
- Daily Doxycycline for Early SyphillisRecruitingNCT06683638Phase 2
- Offering Routine and Rapid Point of Care (POC) Syphilis Testing in Pregnant Patients Presenting to the Emergency DepartmentRecruitingNCT06645106Not applicable
- A Cross-sectional Investigational Study to Evaluate the Sensitivity, Specificity, and Utility of the MedMira Inc. Multiplo® Complete Syphilis (TP/nTP) Antibody Test (POCT) to Diagnose Infectious Syphilis in Participants Attending the Sexual Health Clinic in Ottawa, Ontario.RecruitingNCT06586905Not applicable
- Evaluation of the Diagnostic Sensitivity and Specificity of the Determine™ Syphilis Advanced Test.Not yet recruitingNCT06584214Not applicable
- A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis DisparitiesRecruitingNCT06428643Not applicable
- LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum TreatmentRecruitingNCT06391125Phase 3
- Modernizing Perinatal Syphilis TestingRecruitingNCT06082453Not applicable
- Comparisons of Treatment Responses of Early Syphilis to Benzathine Penicillin G With or Without DoxycyclineRecruitingNCT06069141Not applicable
- MENJAGA: Continuous Quality Improvement for Antenatal HIV, Syphilis and Hepatitis B Testing in IndonesiaNot yet recruitingNCT06058286Not applicable
- The TRIple Elimination Model Of Mother-to-child Transmission Program (TRI-MOM)RecruitingNCT05951751Not applicable
- Syphilis and HIV Point of Care Testing (POCT) in SaskatchewanRecruitingNCT05863117Not applicable
- Vienna HIV Infection Via Sex StudyRecruitingNCT05326061
- Cefixime Clinical TrialRecruitingNCT04958122Phase 3
- Spotting Syphilis: A Dual Point-of-Care Syphilis Screening Initiative in a Low-Resource Healthcare SettingCompletedNCT07498153Not applicableResults posted
- Combination Primary Care and Prevention Services for Women Who Inject Drugs and Exchange Sex in Seattle, WashingtonCompletedNCT06187064Not applicableResults posted
- Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection ScreeningCompletedNCT06100250Not applicableResults posted
- mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) InterventionCompletedNCT06059443Not applicableResults posted
- Treatment Responses of Early Syphilis to Ceftriaxone Plus DoxycyclineTerminatedNCT05980871Phase 4Results posted
- Ending the HIV Epidemic Through Point-of-Care Technologies (EHPOC)CompletedNCT04793750Not applicableResults posted
- Syphilis Self-testing to Expand Test Uptake Among Men Who Have Sex With Men (SST)CompletedNCT04480749Phase 4Results posted
- Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With MenCompletedNCT03980223Phase 4Results posted
- Building Mobile HIV Prevention and Mental Health Support in Low-resource SettingsCompletedNCT03912753Not applicableResults posted
- A Trial to Compare Antibacterial vs. Placebo Mouthwash to Reduce the Incidence of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men (MSM) Taking HIV Pre-Exposure Prophylaxis (PrEP)TerminatedNCT03881007Not applicableResults posted
- Cefixime for Alternative Syphilis TreatmentCompletedNCT03660488Phase 2Results posted
- Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV InfectionCompletedNCT03637660Phase 4Results posted
- Syphilis Response to Higher Penicillin Dosage: The 2.4 Versus 7.2 StudyCompletedNCT02611765Phase 4Results posted
- Lumbar Puncture and Syphilis OutcomeCompletedNCT02031146Not applicableResults posted
- Impact of Covid-19 on SyphilisActive, not recruitingNCT07150871
- Validation of Self Testing Using the INSTI Multiplex HIV1/2 Syphilis Antibody TestTerminatedNCT06953024Not applicable
- Investigational Study to Evaluate the DPP® Syphilis Screen & Confirm Antibody Point-of-care Test (POCT) to Diagnose Infectious SyphilisCompletedNCT06927843
- Cefixime Versus Benzathine Penicillin G in Treatment of Early SyphilisTerminatedNCT06907316Phase 4
- Ayaangwaamiziwin Initiative: Carefulness and PreparednessActive, not recruitingNCT06893159Not applicable
- Periodic Presumptive Treatment vs. doxyPEP for STI Control in Kenyan MSMActive, not recruitingNCT06468462Phase 4
- Retrospective Study of iStatis Syphilis Ab Test (POC)CompletedNCT06367621
- Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis Syphilis Ab Test at the Point- Of-Care SitesCompletedNCT06365606Not applicable
- Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSMActive, not recruitingNCT06188442Phase 4
- HPV Infection, Sexually Transmitted Infections and Anal Dysplasia in the Transgender PopulationCompletedNCT05981807
- Evaluation of the Sensitivity, Specificity, and Utility of the Reveal® TP (Syphilis) Antibody POCTCompletedNCT05831098Not applicable
- Linezolid for Syphilis Pilot StudyCompletedNCT05548426Phase 2
- Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in ZimbabweCompletedNCT05541081Not applicable
- Integrating Enhanced HIV PrEP Into a STI Clinic in LilongweCompletedNCT05307991
- Alternative Antibiotics for SyphilisCompletedNCT05069974Phase 3
- NOWDx Test for the Diagnosis of SyphilisCompletedNCT05063344
- Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the CommunityCompletedNCT04947475Not applicable
- Clinical Trial of Doxycycline VS BPG for Early Syphilis (SY-DOXY)CompletedNCT04838717Phase 3
- Impact of COVID-19 on Provision and Uptake of Prevention of Mother-to-child Transmission of HIV Services in ZimbabweCompletedNCT04782739
- Interventions for Enhancing Adherence to Syphilis Treatment and Follow-up: Study Protocol for the Health Information and Monitoring of Sexually Transmitted Infections (SIM) Randomized Controlled TrialStatus unknownNCT04753125Not applicable
- STI/HIV Intervention Behavioral Intervention ProgramCompletedNCT04547413Not applicable
- Point of Care Tests for Syphilis and HIVCompletedNCT04514848Not applicable
- Acquired Syphlis by Non Sexual ContactCompletedNCT04455425
- Pre-exposure Prophylaxis: A Miracle Drug or a Moral HazardCompletedNCT04325555
- The University of Zimbabwe College of Health Science (UZ-CHS) BIRTH COHORT StudyActive, not recruitingNCT04087239
- Implementation Strategy of Bio-molecular Techniques for Early Diagnose of Congenital Syphilis and Chagas DiseasesStatus unknownNCT04084379
- Sexual Risks in Prep UsersCompletedNCT03975517
- Point-Of-Care Testing for Congenital Syphilis in Mothers and NewbornsWithdrawnNCT03814096Not applicable
- Finding the Latent Treponema PallidumStatus unknownNCT03754517
- Trial Evaluating the Clinical Efficacy of Cefixime for Treatment of Early Syphilis in Non-pregnant WomenStatus unknownNCT03752112Phase 1/2
- Global Syphilis SequencingCompletedNCT03709862
- Impact of the Daily Doxycycline Pre-exposure Prophylaxis (PrEP) on the Incidence of Syphilis, Gonorrhoea and ChlamydiaActive, not recruitingNCT03709459
- Transcriptomic and Next Generation Sequencing Approaches to Infection With Treponema PallidumActive, not recruitingNCT03310424
- Feasibility of Introducing an Onsite Test for Syphilis in the Package of Antenatal Care in Burkina FasoCompletedNCT03156751
- Prevalence of Sexually Transmitted Infections Among People Attending the Sexual Assault Centre in Oslo, Norway.CompletedNCT03132389
- Serological Response to Retreatment of Serofast Early Syphilis Cases With Benzathine PenicillinStatus unknownNCT02884115Phase 4
- The Association Between Molecular Typing of Treponema Pallidum and Treatment Efficacy and Clinical FindingsStatus unknownNCT02871505Phase 4
- Oral Doxycycline for the Prevention of Syphilis in Men Who Have Sex with Men (DaDHS)CompletedNCT02864550Phase 4
- One Dose Versus Three Weekly Doses of Benzathine Penicillin G for Patients With Early SyphilisStatus unknownNCT02857959Phase 4
- Tenofovir/Emtricitabine With Doxycycline for Combination HIV and Syphilis Pre-exposure Prophylaxis in HIV-negative MSMCompletedNCT02844634Phase 4
- The Serum Angiotensin Converting Enzyme and Lysozyme Levels in Patients Non-infectious and Infectious UveitisStatus unknownNCT02627209Not applicable
- Introduction Study of Dual HIV & Syphilis Rapid Diagnostic Tests in Antenatal Clinics in ColombiaCompletedNCT02454816Not applicable
- Texting Intervention to Sustain HIV Prevention in Women in High-drug-use ContextsCompletedNCT02447484Not applicable
- Dual Rapid HIV & Syphilis Tests in ZambiaCompletedNCT02445846
- Syphilis Treatment of Partners TrialStatus unknownNCT02262390Not applicable
- Efficacy of Doxycycline Prophylaxis to Reduce Syphilis in High-Risk, HIV-Positive MSMCompletedNCT02257658Not applicable
- Evaluating the Effectiveness of Point-of-care Diagnostic Technologies in MCH Services in MozambiqueCompletedNCT02191527Not applicable
- Implementation of a Sexual Health Intervention for Young Men Who Have Sex With Men (MSM) in Two Vietnamese CitiesCompletedNCT02122094Not applicable
- Treponema Pallidum-specific Proteomic Changes in Patients With Incident Syphilis InfectionCompletedNCT02059525
- Evaluation of Enhanced Syphilis Screening Among HIV-positive MenCompletedNCT02019043Not applicable
- Comparisons of Serologic Response of Early SyphilisCompletedNCT01944358
- Partner Notification Strategies for MSM in PeruCompletedNCT01720641Not applicable