Small Cell Lung Carcinoma: all 1,234 studies

Page 2 of 13. Open to participants first (350), then studies with results posted, then the rest; newest registration first within each.

• Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung CancerRecruitingNCT07226999Phase 2/3
• Engagement of Veterans With Lung CancerRecruitingNCT07219251Not applicable
• A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)RecruitingNCT07218146Phase 3
• A Study of YL201 and Ivonescimab (AK112) in Advanced Solid TumorsRecruitingNCT07208773Phase 1/2
• Penfluridol for Relapsed/Refractory Small Cell CancersNot yet recruitingNCT07206563Phase 1/2
• Adebrelimab Plus Chemoradiotherapy Followed by Adebrelimab Maintenance in Limited-Stage SCLCNot yet recruitingNCT07200154Phase 2
• 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid TumorsRecruitingNCT07189871Phase 1/2
• Study Comparing ZG006 With Investigator-Selected Chemotherapy in Participants With Relapsed Small Cell Lung CancerRecruitingNCT07189455Phase 3
• A Study of DXC014 in Patients With Advanced Solid Tumors.RecruitingNCT07177937Phase 1
• 7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)RecruitingNCT07175077
• A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung CancerRecruitingNCT07174583Phase 1/2
• Prospective Observational Study on ES-SCLCNot yet recruitingNCT07173946
• A Real-world Study of Adebrelimab-based Combination Regimens in the Treatment of Advanced Solid TumorsNot yet recruitingNCT07173244
• Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)RecruitingNCT07155200Phase 1/2
• A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung CancerRecruitingNCT07155174Phase 2
• Lurbinectedin With Osimertinib in Transformed Small Cell Lung CancerRecruitingNCT07153055Phase 1/2
• Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung CancerRecruitingNCT07149363Phase 2
• DESTINY-PANTUMOUR04RecruitingNCT07124000
• A Clinical Study of BT02 in Treating Patients With Advanced Lung CancerNot yet recruitingNCT07110363Phase 1
• Organoid-guided vs Topotecan Therapy in Relapsed Extensive-Stage Small Cell Lung CancerNot yet recruitingNCT07106528Phase 2/3
• A Study Evaluating Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade for Limited-stage Small Cell Lung CancerNot yet recruitingNCT07103408Phase 2
• A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]RecruitingNCT07099898Phase 3
• Toripalimab Combined With Chemotherapy as Adjuvant Therapy for Incidental Small Cell Lung Cancer After Radical Resection of Lung Cancer: A Single-Center, Randomized Controlled Clinical Study Protocol Number: LungMate-033Not yet recruitingNCT07097948Phase 2
• A Study of QL1706 Combined With Chemotherapy Induction on Sequential Immunotherapy Consolidation in Patients With Limited-Stage Small Cell Lung Cancer After ChemoradiotherapyRecruitingNCT07091305Phase 2
• Prophylactic Proton Pump Inhibition for Esophageal Protection in Lung Radiation TherapyNot yet recruitingNCT07076914Phase 2
• A Phase II/III Study of IBB0979 in Combination With Topotecan Versus Topotecan in Relapsed Small Cell Lung CancerNot yet recruitingNCT07076095Phase 2
• Study of GV20-0251 in Participants With Solid Tumor MalignanciesRecruitingNCT07070518Phase 1/2
• Small Extracellular Vesicle miRNAs as Predictive Biomarkers for Immunochemotherapy Efficacy in Extensive-stage Small Cell Lung CancerRecruitingNCT07070011
• A Study on the First-line Treatment of Small Cell Lung Cancer With Adebrelimab and Vunakizumab and ChemotherapyNot yet recruitingNCT07069270Phase 2
• Sintilimab Combined With Tafolecimab and Chemotherapy as First-Line Treatment for Extensive-Stage Small Cell Lung CancerRecruitingNCT07061535Phase 2
• Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung CancerRecruitingNCT07057791Phase 2
• Durvalumab as Consolidation for Patients LS-SCLCRecruitingNCT07055581Phase 2
• A Study of LY4175408 in Participants With Advanced CancerRecruitingNCT07046923Phase 1
• AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)RecruitingNCT07038343Phase 1/2
• ZG006 and ZG005 in Participants With Small Cell Lung Cancer or Neuroendocrine CarcinomaRecruitingNCT07038096Phase 1/2
• Study of CP-383 in Patients With Advanced or Metastatic Solid TumorsRecruitingNCT07030257Phase 1/2
• A Multi-omics Sequencing-based Model for Predicting Efficacy and Dynamic Monitoring of Treatment in Small Cell Lung CancerRecruitingNCT07026669
• Sintilimab Plus Anlotinib as Second or Further-line Therapy for ES-SCLC Who Have Progressed After Anti-PD-1/L1 TherapyNot yet recruitingNCT07022301Phase 2
• Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized TrialRecruitingNCT07015892Phase 3
• A Study of AK112 as Consolidation Treatment for Patients With Limited Stage Small-cell Lung Cancer Who Have Not Progressed Following Concurrent Chemoradiation TherapyRecruitingNCT07010263Phase 3
• Evaluation of the Value of [68Ga]Ga-PENTIXAFOR PET-CT in Patients With Metastatic Small Cell Lung Cancer (SCLC)Not yet recruitingNCT07007325Early Phase 1
• Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid TumorsRecruitingNCT07006727Phase 1
• Efficacy and Biomarkers of the Second-line Treatment of Adebelizumab Combined With Irinotecan Liposome in Advanced Small Cell Lung CancerNot yet recruitingNCT07004712Phase 2
• Limertinib Plus Carboplatin and Etoposide for EGFR-mutant NSCLC With SCLC Transformation After EGFR-TKI ProgressionNot yet recruitingNCT07001995Phase 2
• This is a Two-cohort, Exploratory Clinical Study Assessing the Activity of Benmelstobart Combined With Chemotherapy With or Without Anlotinib in Resectable Limited-Stage Small Cell Lung CancerNot yet recruitingNCT06978153Phase 2
• A Study of SYS6040 for Injection in Patients With Advanced Solid TumorsRecruitingNCT06970795Phase 1
• Nano-crystalline Megestrol Acetate Combined With Standard Treatment Versus Standard Treatment for First-line Extensive-stage Small Cell Lung Cancer in the Cachexia PhaseNot yet recruitingNCT06961201Phase 3
• A Study of Hospital-at-Home for People Receiving TarlatamabRecruitingNCT06957314Not applicable
• A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung CancerRecruitingNCT06954246Phase 3
• Prospective, Single-arm, Phase II Clinical Study of Irinotecan Hydrochloride Liposome Injection Combined With Platinum and Immune Checkpoint Inhibitors Combined With Anlotinib for the Maintenance of Extensive Small Cell Lung Cancer After First-line InductionNot yet recruitingNCT06951841Phase 4
• A Phase I Study of HS-20108 in Participants With Advanced Solid TumorsRecruitingNCT06936735Phase 1
• Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung CancerRecruitingNCT06931626Phase 1
• Benmelstobart, Anlotinib and Chemotherapy as First-line Treatment for Extensive-stage Small-cell Lung CancerNot yet recruitingNCT06931145Phase 4
• Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung CancerRecruitingNCT06922539Phase 1
• Hypofractionated Radiotherapy Followed by Chemo-immunotherapy Induction TherapyNot yet recruitingNCT06914050Phase 2
• Study of Serplulimab Plus Chemotherapy as Neoadjuvant Therapy for Limited-stage Small Cell Lung Cancer (LS-SCLC)RecruitingNCT06911606Phase 2
• Nanocrystalline Megestrol Acetate for the Treatment of Anorexia-Cachexia Syndrome in Extensive-Stage Small Cell Lung Cancer: A Prospective, Open-Label, Single-Arm Phase II Clinical StudyNot yet recruitingNCT06909383Phase 2
• Safety, Pharmacokinetics and Preliminary Efficacy of CS231295 in Advanced Solid TumorsRecruitingNCT06902350Phase 1
• A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung CancerRecruitingNCT06892548Phase 1/2
• A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) ProductsEnrolling by invitationNCT06885424
• A Study of DC05F01 in Chinese Patients With Recurrent/Refractory Ovarian Cancer and Other Advanced Solid TumorsRecruitingNCT06873555Phase 1/2
• Prediction of Response to PD-L1 Inhibitor After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer Using Multi-omics-based Liquid BiopsyRecruitingNCT06869239
• Second-line Immunotherapy for ES-SCLCRecruitingNCT06853678Not applicable
• Tislelizumab in Combination with Chemotherapy ± Radiotherapy for Extensive-Stage Oligometastatic Small Cell Lung Cancer.Not yet recruitingNCT06851819Phase 2
• Immunonutrition Reduces Acute Esophagitis After Thoracic Radiotherapy in Lung CancerRecruitingNCT06840704Phase 3
• Tislelizumab Combined With Chemotherapy and Relayed Radiotherapy in First-line Treatment of ES-SCLCRecruitingNCT06838208Phase 2
• Clinical Trial for Safety and Effectiveness Evaluation of Tarlatamab (AMG757) With Etoposide, Carboplatin and Atezolizumab in Transformed Small Cell Lung Cancer Patients From Adenocarcinoma After EGFR TKI TreatmentRecruitingNCT06830694Phase 2
• Etoposide Plus Benmelstobart Followed by Maintenance Therapy of Benmelstobart Plus Anlotinib in First-line Treatment of Elderly Patients with Extensive Stage Small Cell Lung Cancer: a Single-arm, Prospective TrialNot yet recruitingNCT06825208
• Irinotecan Liposome(II) Combined with Ivonescimab As Second-line Treatment for Small Cell Lung Cancer : a Prospective, Single-arm, Multicenter Clinical StudyNot yet recruitingNCT06820762Phase 2
• Chemotherapy-immunotherapy-based Split-course Adaptive Hypofractionated Radiotherapy for Extensive-stage SCLCEnrolling by invitationNCT06816966Phase 2
• A Study of Valemetostat in Combination With Atezolizumab in People With Lung CancerRecruitingNCT06807632Phase 1
• A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-KitRecruitingNCT06805825Phase 1
• a Study of QL1706 or QL1604 in Patients With Limited-stage Small Cell Lung Cancer After Chemoradiotherapy.Not yet recruitingNCT06789796Phase 3
• A Single-arm, Multicenter, Prospective Phase II Clinical Study of Apatinib in Combination With Adebrelimab and EC Regimen in the First-line Treatment of Extensive Small Cell Lung CancerNot yet recruitingNCT06786312Phase 2
• Adebrelimab Maintenance Therapy After Concurrent Chemoradiotherapy with Hyperfractionated Radiotherapy in Limited-Stage Small Cell Lung CancerNot yet recruitingNCT06784206Phase 2
• A Study on the Efficacy of Atezolizumab Combined with ChemotherapyRecruitingNCT06780826
• A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)RecruitingNCT06780137Phase 1/2
• SERS-Based Serum Molecular Spectral Screening for Lung Cancer TypeNot yet recruitingNCT06775002
• Adjuvant Adebrelimab Plus Apatinib After Chemoradiation in Limited-Stage Small Cell Lung CancerEnrolling by invitationNCT06773156Phase 2
• Association of Thoraco-mediastinal Radiotherapy With Maintenance Immunotherapy Treatment With AtezolizumabRecruitingNCT06771518Phase 2
• Phase II Study of Ivonescimab and Cadonilimab in Combination with Chemotherapy in Patients with ES-SCLCRecruitingNCT06769971Phase 2
• Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM StudyRecruitingNCT06769126Phase 2
• Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung CancerRecruitingNCT06758700Phase 2
• Liposomal Irinotecan and Apatinib in ES-SCLCRecruitingNCT06749691Phase 2
• INK Cells As Maintenance Therapy After Chemoradiotherapy for Small Cell Lung CancerEnrolling by invitationNCT06747832Early Phase 1
• Irinotecan Liposome (II) or Etoposide Combined With Adebrelimab and Carboplatin in the Treatment of ES-SCLCRecruitingNCT06739928Phase 2
• The Diagnostic Value of Bronchoscopic Needle-based Confocal Laser Endomicroscopy (nCLE) As a Real-time Detection Tool for Diagnosing Peripheral Lung Cancer: a Multi-centre Randomised Controlled TrialNot yet recruitingNCT06739421Not applicable
• Sarcopenia and Cachexia in Patients With Lung CancerEnrolling by invitationNCT06730685
• Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid TumorsRecruitingNCT06726148Phase 1/2
• A Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in the Treatment of Advanced Malignant Solid TumorsNot yet recruitingNCT06724263Phase 2
• Concurrent Chemoradiotherapy Combined With Toripalimab and Surufatinib in the Treatment of Limited-Stage Small Cell Lung CancerRecruitingNCT06719700Phase 2
• Addition of Thoracic Consolidation Radiotherapy to the Maintenance Immunotherapy for ES-SCLC (STONE-001)Not yet recruitingNCT06719336Phase 3
• Genomic and Methylation Markers in SCLC and LCNEC for Chemo-Immunotherapy Resistance Prediction (STRATUS)RecruitingNCT06717243
• Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung CancerRecruitingNCT06712355Phase 3
• Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and CarboplatinRecruitingNCT06698965Phase 2
• Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLCRecruitingNCT06681220Phase 1/2
• Adebrelimab Combined with Chemotherapy and Thoracic Radiotherapy for First-line Treatment of ES-SCLCNot yet recruitingNCT06672133Phase 3
• Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC).RecruitingNCT06663098Phase 2
• A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).RecruitingNCT06646276Phase 3
• A Phase II Study of Ivonescimab Combined with Cadonilimab and Chemotherapy in Extensive-stage Small Cell Lung CancerNot yet recruitingNCT06620796Phase 2

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